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The map label for this gene is htpX

Identifier: 161869763

GI number: 161869763

Start: 790034

End: 790873

Strand: Reverse

Name: htpX

Synonym: NMCC_0783

Alternate gene names: 161869763

Gene position: 790873-790034 (Counterclockwise)

Preceding gene: 161869771

Following gene: 161869757

Centisome position: 36.73

GC content: 55.83

Gene sequence:

>840_bases
GTGAAACGAATTTTTCTGTTTTTGGCTACCAATATCGCTGTTTTGGTCGTAATCAACATTGTTTTGGCGGTTTTGGGCAT
CAACAGCCGGGGCGGCGCGGGCAGCCTGTTGGCGTATTCCGCCGTCGTCGGCTTCACTGGTTCGATTATTTCGCTGCTGA
TGTCCAAATTCATCGCCAAACAATCGGTCGGCGCGGAAGTTATCGACACGCCGCGCACCGAAGAAGAAGCCTGGCTTTTG
AACACTGTCGAAGCCCAAGCGCGGCAATGGAACCTGAAAACACCCGAGGTCGCCATCTACCACTCCCCCGAACCCAATGC
CTTTGCCACGGGCGCATCGAGAAACAGCTCCCTGATCGCCGTCAGCACCGGTTTGCTCGACCATATGACGCGCGACGAAG
TGGAAGCCGTATTGGCGCACGAAATGGCACACGTCGGCAACGGCGATATGGTTACGCTGACGCTGATTCAAGGCGTGGTC
AATACCTTTGTCGTGTTCCTGTCGCGCATTATTGCCAACCTGATTGCCCGAAACAACGACGGCAGCCAGTCCCAGGGAAC
TTATTTCCTGGTCAGCATGGTATTCCAAATCCTGTTCGGCTTCCTTGCCAGCTTAATTGTCATGTGGTTCAGCCGACAAC
GCGAATACCGCGCCGATGCGGGCGCGGCAAAACTGGTCGGCGCGCCGAAAATGATTTCCGCCCTGCAAAGGCTCAAAGGC
AACCCGGTCGATTTGCCCGAAGAAATGAACGCAATGGGCATCGCCGGAGATACGCGCGACTCCCTGCTCAGCACCCACCC
TTCGCTGGACAACCGAATCGCCCGCCTCAAATCGCTTTAA

Upstream 100 bases:

>100_bases
TTTTGCATACCTTTGCCGAGTCTGATATTCACAAGCCGGCAACTTTTTGGGACAATCCCCAAAATTTCAAAACATCACAC
CCTACCAAAAAGGAACATCC

Downstream 100 bases:

>100_bases
ACCGATTTGAAACGGCAAAAACCGTACGCGCAAGCAGTACGGTTTTTTGTATATGCTGTCTGAAAACATCAGGTTTCCAT
ACCGACACCAACCGTATCCA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKRIFLFLATNIAVLVVINIVLAVLGINSRGGAGSLLAYSAVVGFTGSIISLLMSKFIAKQSVGAEVIDTPRTEEEAWLL
NTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRNSSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVV
NTFVVFLSRIIANLIARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPKMISALQRLKG
NPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARLKSL

Sequences:

>Translated_279_residues
MKRIFLFLATNIAVLVVINIVLAVLGINSRGGAGSLLAYSAVVGFTGSIISLLMSKFIAKQSVGAEVIDTPRTEEEAWLL
NTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRNSSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVV
NTFVVFLSRIIANLIARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPKMISALQRLKG
NPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARLKSL
>Mature_279_residues
MKRIFLFLATNIAVLVVINIVLAVLGINSRGGAGSLLAYSAVVGFTGSIISLLMSKFIAKQSVGAEVIDTPRTEEEAWLL
NTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRNSSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVV
NTFVVFLSRIIANLIARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPKMISALQRLKG
NPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARLKSL

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family

Homologues:

Organism=Escherichia coli, GI1788133, Length=291, Percent_Identity=54.9828178694158, Blast_Score=299, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HTPX_NEIG1 (Q5F9J4)

Other databases:

- EMBL:   AE004969
- RefSeq:   YP_207555.1
- ProteinModelPortal:   Q5F9J4
- SMR:   Q5F9J4
- STRING:   Q5F9J4
- MEROPS:   M48.002
- EnsemblBacteria:   EBNEIT00000002079
- GeneID:   3283010
- GenomeReviews:   AE004969_GR
- KEGG:   ngo:NGO0399
- NMPDR:   fig|242231.4.peg.793
- eggNOG:   COG0501
- GeneTree:   EBGT00050000020861
- HOGENOM:   HBG739460
- OMA:   KMISALE
- PhylomeDB:   Q5F9J4
- ProtClustDB:   PRK05457
- BioCyc:   NGON242231:NGO0399-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00188
- InterPro:   IPR022919
- InterPro:   IPR001915

Pfam domain/function: PF01435 Peptidase_M48

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30172; Mature: 30172

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 141-141

Signals:

None

Transmembrane regions:

HASH(0x1585b06c)-; HASH(0x15373c10)-; HASH(0x164c4894)-; HASH(0x164c47d4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIFLFLATNIAVLVVINIVLAVLGINSRGGAGSLLAYSAVVGFTGSIISLLMSKFIAK
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRNSSLIA
HHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEECCCCCCCCEEE
VSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVVNTFVVFLSRIIANLIARNND
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPKMISALQRLKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCC
NPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARLKSL
CCCCCCHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCH
>Mature Secondary Structure
MKRIFLFLATNIAVLVVINIVLAVLGINSRGGAGSLLAYSAVVGFTGSIISLLMSKFIAK
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRNSSLIA
HHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEECCCCCCCCEEE
VSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVVNTFVVFLSRIIANLIARNND
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPKMISALQRLKG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCC
NPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARLKSL
CCCCCCHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA