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The map label for this gene is xerC [H]

Identifier: 161869347

GI number: 161869347

Start: 353145

End: 354062

Strand: Direct

Name: xerC [H]

Synonym: NMCC_0353

Alternate gene names: 161869347

Gene position: 353145-354062 (Clockwise)

Preceding gene: 161869337

Following gene: 161869348

Centisome position: 16.4

GC content: 62.2

Gene sequence:

>918_bases
ATGGTTTTGGACGGGTTTGCGGCGCATTTTGACGCTTATTTGGAAAATATCGTGCGCGAGGGCAAGTCGGAGCACACGGT
GGCGGCATACCGGCGCGATTTGGAAGAACTGTTTGCGCTGTTGGCACAAATGCCGTCTGAAGCTGAAGGCGGCGTGCCGC
AGGGCTTGTCGCGGCGCGATTTTACGGCGGCGTTGCGGCGGCTGTCGCAGCGCGGTTTGAATGCGCGGACGCTGGCGCGC
AAGCTGTCGTCTTGGCGGCAGTATTGTGTTTGGCTGGTGGAACGCGGTCTGCTGCATACCGACCCGACCGCCGACATCAA
ACCGCCGAAGCAGCCCGAGCGCGTACCCAAAGCCCTGCCGCAGGAATGGCTGAACCGGATGCTGGATTTGCCCGTGGACG
GCGGCGACCCGCTGGCGGTGCGCGATCACGCCCTGTTCGAGCTGATGTACGGCAGCGGTTTGCGCGTGAGCGAGATACAC
GGCTTGAATGCAGATGATGTCTATTTGGACGAGGCGTGGGTACACGTTACCGGCAAAGGGCGCAAGCAGCGGCAGGTGCC
GCTGACCGGCAAAAGCGTGGAAGCCCTGAAAAACTATCTGCCGCTGCGTCAGACGGCATCGGACGGCAAAGCCCTGTTTA
CCGGCAGGAACGGCACGCGCCTGAGCCAACGCCAAATCCAAAAACGTTTGGCGCAATGGGCGGCGCAAAACGGCGACGGC
AGGCACGTTTCGCCGCATATGATGCGCCACAGCTACGCCGGACACCTGTTGCAGGCTTCGCGCGACATCCGGGCGGTGCA
GGAGCTGCTCGGGCACAGCAGCCTTTCGACCACGCAGATTTACACCAAACTCGATTTCGACCACATCGCCCGCCTGTATG
ACGAAGCCCACCCGCGCGCCAAGCGGCAGGACGAATGA

Upstream 100 bases:

>100_bases
AACGGCGGGCGGACGGGTCGGATTTTGGGCAGTTCGGGGTTTTGGTGTGTCGTTTATGATAATGTTTTCACTGTTTTTTT
GATATTTGTGTGGGGCGGTT

Downstream 100 bases:

>100_bases
CATACGGCAAAATCAGCCGTCAGCCGCACGCTCTTGATATATAATTGGTCGTTGCACCTGGACGACACATAAAAAAGACA
CACCATGAACCCAAGCCCCC

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQMPSEAEGGVPQGLSRRDFTAALRRLSQRGLNARTLAR
KLSSWRQYCVWLVERGLLHTDPTADIKPPKQPERVPKALPQEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIH
GLNADDVYLDEAWVHVTGKGRKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNGTRLSQRQIQKRLAQWAAQNGDG
RHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLSTTQIYTKLDFDHIARLYDEAHPRAKRQDE

Sequences:

>Translated_305_residues
MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQMPSEAEGGVPQGLSRRDFTAALRRLSQRGLNARTLAR
KLSSWRQYCVWLVERGLLHTDPTADIKPPKQPERVPKALPQEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIH
GLNADDVYLDEAWVHVTGKGRKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNGTRLSQRQIQKRLAQWAAQNGDG
RHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLSTTQIYTKLDFDHIARLYDEAHPRAKRQDE
>Mature_305_residues
MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQMPSEAEGGVPQGLSRRDFTAALRRLSQRGLNARTLAR
KLSSWRQYCVWLVERGLLHTDPTADIKPPKQPERVPKALPQEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIH
GLNADDVYLDEAWVHVTGKGRKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNGTRLSQRQIQKRLAQWAAQNGDG
RHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLSTTQIYTKLDFDHIARLYDEAHPRAKRQDE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=280, Percent_Identity=44.2857142857143, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1789261, Length=299, Percent_Identity=35.1170568561873, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790767, Length=169, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790768, Length=160, Percent_Identity=28.75, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34508; Mature: 34508

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQMPSEAEGGVPQGLSRRD
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FTAALRRLSQRGLNARTLARKLSSWRQYCVWLVERGLLHTDPTADIKPPKQPERVPKALP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
QEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIHGLNADDVYLDEAWVHVTGKG
HHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHCCCCCCCEEECCEEEEEECCC
RKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNGTRLSQRQIQKRLAQWAAQNGDG
CCCCCCCCCCHHHHHHHHHCCCHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
RHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLSTTQIYTKLDFDHIARLYDEAHPRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCC
KRQDE
CCCCC
>Mature Secondary Structure
MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQMPSEAEGGVPQGLSRRD
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FTAALRRLSQRGLNARTLARKLSSWRQYCVWLVERGLLHTDPTADIKPPKQPERVPKALP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
QEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIHGLNADDVYLDEAWVHVTGKG
HHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHCCCCCCCEEECCEEEEEECCC
RKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNGTRLSQRQIQKRLAQWAAQNGDG
CCCCCCCCCCHHHHHHHHHCCCHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
RHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLSTTQIYTKLDFDHIARLYDEAHPRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCC
KRQDE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA