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The map label for this gene is pyrR [H]

Identifier: 161525691

GI number: 161525691

Start: 2742039

End: 2742551

Strand: Reverse

Name: pyrR [H]

Synonym: Bmul_2522

Alternate gene names: 161525691

Gene position: 2742551-2742039 (Counterclockwise)

Preceding gene: 161525692

Following gene: 161525690

Centisome position: 79.53

GC content: 73.1

Gene sequence:

>513_bases
ATGAGCCCCATTGACGCCGAGGCGCTGTACCGCGCCCTGCTCGACCAGATCCGTGCCGCGTACGGCACCGCGTTCGCCGA
ACCGGGCGGCCCGCGGCTCGCCGGCATCTACAGCGGCGGGGCCTGGCTCGCCGAGCGTCTCGCGCGCGATCTCGGCGCGC
CGGCGTTCGGCGTCGTCAACGTCGCGCTGCATCGCGACGACTACGCGAAGAAGGGGTTGCACAGCCAGGCGAGCCCGACG
TCGCTGCCGTTCGACGTCGACGGCGCGCGCATCGTGCTCGTCGACGACGTGCTGTACACCGGCCGCACCGTGCGCGCCGC
GCTGAACGAACTGTTCGACTACGGCCGTCCGGCTGCCGTCGAACTCGCCGTGCTCGCCGATCGCGGCGGACGCGAGCTGC
CGGTCGCCGCGCGCTTTGCCGGCGGCACGCTGGACGTGCCGGCCGGCGCGACGCTCGTGCTCGCGCGCGACGATTCGCAG
TTCACGCTGAACGTCGAGGCGCAAGCCGCCTGA

Upstream 100 bases:

>100_bases
ATGCGCGAGCGCAACGTGCGCGGCCGCGCACGCACCGACATGCTCGACGCCGAAGCCGCGCGCGTGATCCTTCAACAGTA
TCTCGATCAATTGTCCGACC

Downstream 100 bases:

>100_bases
ACGACCGCGAAACCGTATCCCGGGCCGCCGGTTCGCGCCGCGGCCCGTTTGCATAGTTGGAATCACGCACACCATGACCA
CCGACACCACTGGCCGCACC

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSPIDAEALYRALLDQIRAAYGTAFAEPGGPRLAGIYSGGAWLAERLARDLGAPAFGVVNVALHRDDYAKKGLHSQASPT
SLPFDVDGARIVLVDDVLYTGRTVRAALNELFDYGRPAAVELAVLADRGGRELPVAARFAGGTLDVPAGATLVLARDDSQ
FTLNVEAQAA

Sequences:

>Translated_170_residues
MSPIDAEALYRALLDQIRAAYGTAFAEPGGPRLAGIYSGGAWLAERLARDLGAPAFGVVNVALHRDDYAKKGLHSQASPT
SLPFDVDGARIVLVDDVLYTGRTVRAALNELFDYGRPAAVELAVLADRGGRELPVAARFAGGTLDVPAGATLVLARDDSQ
FTLNVEAQAA
>Mature_169_residues
SPIDAEALYRALLDQIRAAYGTAFAEPGGPRLAGIYSGGAWLAERLARDLGAPAFGVVNVALHRDDYAKKGLHSQASPTS
LPFDVDGARIVLVDDVLYTGRTVRAALNELFDYGRPAAVELAVLADRGGRELPVAARFAGGTLDVPAGATLVLARDDSQF
TLNVEAQAA

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 17850; Mature: 17719

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIDAEALYRALLDQIRAAYGTAFAEPGGPRLAGIYSGGAWLAERLARDLGAPAFGVVN
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHEEE
VALHRDDYAKKGLHSQASPTSLPFDVDGARIVLVDDVLYTGRTVRAALNELFDYGRPAAV
EEEECCHHHHHCCCCCCCCCCCCEECCCCEEEEEECCHHCCHHHHHHHHHHHHCCCCCCE
ELAVLADRGGRELPVAARFAGGTLDVPAGATLVLARDDSQFTLNVEAQAA
EEEEEECCCCCCCCEEEEECCCEEECCCCEEEEEEECCCEEEEEEEEECC
>Mature Secondary Structure 
SPIDAEALYRALLDQIRAAYGTAFAEPGGPRLAGIYSGGAWLAERLARDLGAPAFGVVN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHEEE
VALHRDDYAKKGLHSQASPTSLPFDVDGARIVLVDDVLYTGRTVRAALNELFDYGRPAAV
EEEECCHHHHHCCCCCCCCCCCCEECCCCEEEEEECCHHCCHHHHHHHHHHHHCCCCCCE
ELAVLADRGGRELPVAARFAGGTLDVPAGATLVLARDDSQFTLNVEAQAA
EEEEEECCCCCCCCEEEEECCCEEECCCCEEEEEEECCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]