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The map label for this gene is acoC [H]

Identifier: 161524609

GI number: 161524609

Start: 1580253

End: 1581368

Strand: Direct

Name: acoC [H]

Synonym: Bmul_1436

Alternate gene names: 161524609

Gene position: 1580253-1581368 (Clockwise)

Preceding gene: 161524608

Following gene: 161524610

Centisome position: 45.82

GC content: 70.16

Gene sequence:

>1116_bases
ATGTCGATTCACATGATCACGATGCCCAAGTGGGGGCTGTCGATGGAGCAGGGGCAGGTCAACGGCTGGCTGAAGTCGGT
CGGCGAACGCGTGTCGAAGGGCGACGAGGTGCTCGACGTCGAAACCGACAAGATCTCGTCGGGCGTCGAATGCGCATTCG
ACGGCACGCTGCGCCGGCAGGTCGCTCAGGAGGGCGAAACGCTGCCGGTCGGGGCGCTGCTCGGCGTGGTCGCCGCGGCC
GACGTGAGCGATGCCGACATCGACGCGGCGATCGCGGCATTCCAGCGCGACTACACGCCGAGCGCGGCGGCCGACGAAGC
GGCCGGCCCGCAACCGGAGAAGGCGCAGATCGGCGGCCGCACGATGCGCTTCCTGAAGCTCGGCGACGGCGCCGGGACGC
CGGCCGTGCTGATCCACGGCTTCGGCGGCGACCTGAACAACTGGCTGTTCAATCATGCGGAACTGGCGGCGCACCGGCCG
GTGTGGGCGCTCGATCTGCCCGGTCACGGCGAGTCGGGCAAGGCGGTCGAGCGCGGCAGCCTCGACGAGCTCGCCGACGC
CGTGCTGGCGCTGCTCGACGCGAAGGACATCGAACGCGCGCACCTGATCGGCCATTCGATGGGCGGCGCGGTCGCGATGA
CGGTCGCCGAGCGTGCGCCGGCGCGCGTCGCGTCGCTGACGCTGATCGCGAGCGCGGGCCTCGGTGCCGAGATCAACCGC
GACTACATCGACGGCTTCGTCGCCGGCAACAGCCGCAATACGCTGAAGCCGCATCTCGGCGCGCTGTTCGCGGACAGCGC
GCTCGTCACGCGACAGCTCGTCGACGATCTCGTCAAATACAAGCGGCTCGAAGGCGTGCAGGCCGCGCTCGAGAAGATCG
CGAACGCCGCGTTCGACGGCGCGACGCAGCGGCGCGTGTTCCGCGACCGGCTTGCGTCGCTCGCGCCGCGCACGCTCGTG
ATCTGGGGCGAGCGCGACCAGGTGATTCCGGCGCAGCACGCGCACGGCTTGCCGGACGGCGTGCGCACCGAGCTGATCGC
CGGCAGCGGGCACATGGTGCAGATGGAAGCGGCGGCCGACGTGAACCGGCTGATCGTCGCGTTTCTCGGAGACTGA

Upstream 100 bases:

>100_bases
CCGCATACGCCCGCGCCGTTCGCCGGCGTGCTCGAGGATTTGTATATCCCGTCTGCCGATGCGATCGCGCAGGCCGTGCT
GAAAACGAGGAGCTGAGACG

Downstream 100 bases:

>100_bases
CGATGGCTGCCGCGCTCGAACGACCCAGCCTCACCGCGCTCGGCCAGCCGGGCGCGCGCAGCCGCGACAAGCTCGCGCGC
ATTCCCGTGCGCGTCGAGCC

Product: branched-chain alpha-keto acid dehydrogenase subunit E2

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSIHMITMPKWGLSMEQGQVNGWLKSVGERVSKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAA
DVSDADIDAAIAAFQRDYTPSAAADEAAGPQPEKAQIGGRTMRFLKLGDGAGTPAVLIHGFGGDLNNWLFNHAELAAHRP
VWALDLPGHGESGKAVERGSLDELADAVLALLDAKDIERAHLIGHSMGGAVAMTVAERAPARVASLTLIASAGLGAEINR
DYIDGFVAGNSRNTLKPHLGALFADSALVTRQLVDDLVKYKRLEGVQAALEKIANAAFDGATQRRVFRDRLASLAPRTLV
IWGERDQVIPAQHAHGLPDGVRTELIAGSGHMVQMEAAADVNRLIVAFLGD

Sequences:

>Translated_371_residues
MSIHMITMPKWGLSMEQGQVNGWLKSVGERVSKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAA
DVSDADIDAAIAAFQRDYTPSAAADEAAGPQPEKAQIGGRTMRFLKLGDGAGTPAVLIHGFGGDLNNWLFNHAELAAHRP
VWALDLPGHGESGKAVERGSLDELADAVLALLDAKDIERAHLIGHSMGGAVAMTVAERAPARVASLTLIASAGLGAEINR
DYIDGFVAGNSRNTLKPHLGALFADSALVTRQLVDDLVKYKRLEGVQAALEKIANAAFDGATQRRVFRDRLASLAPRTLV
IWGERDQVIPAQHAHGLPDGVRTELIAGSGHMVQMEAAADVNRLIVAFLGD
>Mature_370_residues
SIHMITMPKWGLSMEQGQVNGWLKSVGERVSKGDEVLDVETDKISSGVECAFDGTLRRQVAQEGETLPVGALLGVVAAAD
VSDADIDAAIAAFQRDYTPSAAADEAAGPQPEKAQIGGRTMRFLKLGDGAGTPAVLIHGFGGDLNNWLFNHAELAAHRPV
WALDLPGHGESGKAVERGSLDELADAVLALLDAKDIERAHLIGHSMGGAVAMTVAERAPARVASLTLIASAGLGAEINRD
YIDGFVAGNSRNTLKPHLGALFADSALVTRQLVDDLVKYKRLEGVQAALEKIANAAFDGATQRRVFRDRLASLAPRTLVI
WGERDQVIPAQHAHGLPDGVRTELIAGSGHMVQMEAAADVNRLIVAFLGD

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=290, Percent_Identity=26.551724137931, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 39206; Mature: 39075

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHMITMPKWGLSMEQGQVNGWLKSVGERVSKGDEVLDVETDKISSGVECAFDGTLRRQ
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHCCCCCEEEECHHHHHH
VAQEGETLPVGALLGVVAAADVSDADIDAAIAAFQRDYTPSAAADEAAGPQPEKAQIGGR
HHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCC
TMRFLKLGDGAGTPAVLIHGFGGDLNNWLFNHAELAAHRPVWALDLPGHGESGKAVERGS
EEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
LDELADAVLALLDAKDIERAHLIGHSMGGAVAMTVAERAPARVASLTLIASAGLGAEINR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHCCHHHHHHHEEECCCCCCCCCH
DYIDGFVAGNSRNTLKPHLGALFADSALVTRQLVDDLVKYKRLEGVQAALEKIANAAFDG
HHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATQRRVFRDRLASLAPRTLVIWGERDQVIPAQHAHGLPDGVRTELIAGSGHMVQMEAAAD
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCCCHHHHEEECCCCEEEEHHHCC
VNRLIVAFLGD
CCCEEEEEECC
>Mature Secondary Structure 
SIHMITMPKWGLSMEQGQVNGWLKSVGERVSKGDEVLDVETDKISSGVECAFDGTLRRQ
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHCCCCCEEEECHHHHHH
VAQEGETLPVGALLGVVAAADVSDADIDAAIAAFQRDYTPSAAADEAAGPQPEKAQIGGR
HHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCC
TMRFLKLGDGAGTPAVLIHGFGGDLNNWLFNHAELAAHRPVWALDLPGHGESGKAVERGS
EEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
LDELADAVLALLDAKDIERAHLIGHSMGGAVAMTVAERAPARVASLTLIASAGLGAEINR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHCCHHHHHHHEEECCCCCCCCCH
DYIDGFVAGNSRNTLKPHLGALFADSALVTRQLVDDLVKYKRLEGVQAALEKIANAAFDG
HHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATQRRVFRDRLASLAPRTLVIWGERDQVIPAQHAHGLPDGVRTELIAGSGHMVQMEAAAD
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCCCHHHHEEECCCCEEEEHHHCC
VNRLIVAFLGD
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]