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The map label for this gene is bioD [H]

Identifier: 161523552

GI number: 161523552

Start: 408956

End: 409675

Strand: Reverse

Name: bioD [H]

Synonym: Bmul_0372

Alternate gene names: 161523552

Gene position: 409675-408956 (Counterclockwise)

Preceding gene: 161523553

Following gene: 161523551

Centisome position: 11.88

GC content: 71.67

Gene sequence:

>720_bases
ATGAGCACACCGCTTTCGCTGTTCGTCACGGGCACCGACACCGAGATCGGCAAGACCTTCGTGTCGGCCGCGCTGCTGCA
CGGCTTCGCACGGCACGGGCTGCGCGCGGCCGCGATGAAGCCGGTCGCGGCCGGCGCCTATGAGCGCGACGGCGTGTGGC
GCAACGAAGACGCCGATCAGCTCGATGCGGCCGCGAGCGTCGTGCTGCCGCCCGAGCTGCGCACCCCCTTCCTGCTGAAG
GCCCCCGCCGCGCCGCACATCGTCGCCGCGCACGAGCACGTGACGCTCGACATCGACACGATCGTCGCATGCCATCGCGA
CGCGCTGACGCGTGCGGACATCGTCGTCGTCGAAGGCGTCGGCGGCTTTCGCGTGCCGCTGAACGACACGCAGGACACCG
CCGATCTCGCGGTCGCGCTCGGCCTGCCGGTCGTGCTCGTGGTCGGCATGCGGCTCGGCTGCATCAGCCATGCGCTGCTG
ACCGCCGACGCGATCGCGGCGCGCGGGCTCACGCTTGCCGGTTGGGTCGCGAACCACGTCGATCCGGCGATGACTTACGC
CGACGAGAACGTCGCGACGATTCGCGACTGGCTCGCGCGCGAGCATCGCGCACCGCTCCTCGGCCGCATCGCCCACATGG
CGCCGGCCGACCCCGAATCCGCCGCGGCGACGCTCGACATCGCCGCGCTCGTCGACACGTTGCGCGCCGCGCAGCGTTGA

Upstream 100 bases:

>100_bases
CCGGCACCTCGCGGCTACGCATCTCGCTGTCGGCCGCGCATTCGTTCGACGATCTCGCGCGGCTCGAAACCGCGCTGCTG
CGCGCAAGCGAGGAGGCCGC

Downstream 100 bases:

>100_bases
CTCCCCGATCTCACCCCTCCAGTCAGGACAGGAAAACGAAATGACCCAAGCCCAGACCGCCGCCGCGCAACCCGACGCGA
TTCCCGTGGCAGCGCCGTCG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSTPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAYERDGVWRNEDADQLDAAASVVLPPELRTPFLLK
APAAPHIVAAHEHVTLDIDTIVACHRDALTRADIVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGMRLGCISHALL
TADAIAARGLTLAGWVANHVDPAMTYADENVATIRDWLAREHRAPLLGRIAHMAPADPESAAATLDIAALVDTLRAAQR

Sequences:

>Translated_239_residues
MSTPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAYERDGVWRNEDADQLDAAASVVLPPELRTPFLLK
APAAPHIVAAHEHVTLDIDTIVACHRDALTRADIVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGMRLGCISHALL
TADAIAARGLTLAGWVANHVDPAMTYADENVATIRDWLAREHRAPLLGRIAHMAPADPESAAATLDIAALVDTLRAAQR
>Mature_238_residues
STPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAYERDGVWRNEDADQLDAAASVVLPPELRTPFLLKA
PAAPHIVAAHEHVTLDIDTIVACHRDALTRADIVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGMRLGCISHALLT
ADAIAARGLTLAGWVANHVDPAMTYADENVATIRDWLAREHRAPLLGRIAHMAPADPESAAATLDIAALVDTLRAAQR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=215, Percent_Identity=45.1162790697674, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI87081944, Length=228, Percent_Identity=38.1578947368421, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324385, Length=171, Percent_Identity=35.0877192982456, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25155; Mature: 25024

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAYERDGVWRNEDADQ
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCHHCCCCCCCCCCCCCCHHH
LDAAASVVLPPELRTPFLLKAPAAPHIVAAHEHVTLDIDTIVACHRDALTRADIVVVEGV
HHHHHEEEECCCCCCCEEEECCCCCCEEEECCEEEEEHHHHHHHHHHHHCCCCEEEEECC
GGFRVPLNDTQDTADLAVALGLPVVLVVGMRLGCISHALLTADAIAARGLTLAGWVANHV
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
DPAMTYADENVATIRDWLAREHRAPLLGRIAHMAPADPESAAATLDIAALVDTLRAAQR
CHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAAMKPVAAGAYERDGVWRNEDADQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCHHCCCCCCCCCCCCCCHHH
LDAAASVVLPPELRTPFLLKAPAAPHIVAAHEHVTLDIDTIVACHRDALTRADIVVVEGV
HHHHHEEEECCCCCCCEEEECCCCCCEEEECCEEEEEHHHHHHHHHHHHCCCCEEEEECC
GGFRVPLNDTQDTADLAVALGLPVVLVVGMRLGCISHALLTADAIAARGLTLAGWVANHV
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
DPAMTYADENVATIRDWLAREHRAPLLGRIAHMAPADPESAAATLDIAALVDTLRAAQR
CHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA