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The map label for this gene is glpD

Identifier: 161486609

GI number: 161486609

Start: 2655438

End: 2656979

Strand: Direct

Name: glpD

Synonym: VV2626

Alternate gene names: 161486609

Gene position: 2655438-2656979 (Clockwise)

Preceding gene: 37680809

Following gene: 37680811

Centisome position: 79.16

GC content: 51.43

Gene sequence:

>1542_bases
ATGAAGAACAACTCCTCCACACCTACATCAACACTCGACATCTTGGTTGTCGGGGGTGGTATCAATGGCGCAGGCATCGC
AGCAGATGCGGCAGGACGTGGCCTTAGTGTCGCGCTTTTTGAAGCCAAAGATTTTGCCTCGGCGACCTCTTCAGCCAGCT
CGAAACTGATCCATGGTGGTCTGCGCTATTTGGAACATTATGAGTTTCGTTTGGTCTCCGAAGCTCTGGCGGAACGCGAA
GTGCTGATCAAAAAAGCGCCGCACATTGCCTTTCCAATGCGTTTTCGCTTGCCGCACCGCTCCTATCTTCGCCCCGCGTG
GATGATTCGTTGCGGGCTGTTTTTGTATGATCACTTAGGTAAGCGCACCACACTGCCTAGCAGCCATAAGGTGAACCTTG
CCGAAACCGGGCTGCTGAAAGAGGAAATGAAAATTGGCTTTGAGTATTCCGATTGTTGGGTCGACGATGCTCGCCTCACG
TTACTGAATGCCATCAGTGCCAAACGCAATGGAGCAGAGGTGCGTAATTACTGCAAAGTGAGCAAAGCTGAGCGTGTTGA
CGGCCTTTGGAAAGTCACCATTGAAGATCAGCAAAATGGTGAACAGTTTGTGCGTTACGCCAAAGCCTTGGTCAACGCGG
CGGGCCCTTGGGTGAAACAATTTTATGATGACAGTTTAGATGGCCCATCACCACGCAACATTCGTTTGATCAAAGGTTCA
CACATTGTCGTGCCACGCGTACATCCCGATCCGCAAGCTTACATCCTGCAAAACAACGATGGGCGGATTGTGTTTGTGAT
TCCTTATCTGGATAAGTTCTCAATTGTCGGCACAACGGACGTCGAATACACCGGTGACCCTCGCCACGTGGCGATTTCAG
AACAGGAAGTTGACTACTTAATTGATATTGTTAATCAGCATTTTGTCCACCAACTGAGCAAACAAGATGTGGTGTGGACT
TACAGTGGTGTCCGACCGCTGTGCGATGATGAATCCGATTCCCCCCAAGCCATCACGCGTGATTACACCATCGAGCTGGA
GCAAGAACTTGACCAAGCACCGCTGCTCTCTATTTTCGGTGGCAAACTGACGACATATCGCAAGTTGGCGGAGTCTGCCA
TGCGTAAACTCGCGCCCTATTTCGACCATATGGGCACACCGTGGACGGCGCAACAAACGCTCCCCGGCGGTGATTTTAGC
TGTACACGAGAACAGCTCGCCCACGCGTTGCGCCAACAATACCCTTGGTTGAGTGCAACCTTAGCCTACCGTTATGTCTG
CCAATACGGCAGCGATGCACGCCAATTGCTCGCGGGGGCAGAAGAGGTATCAGCAATGGGCATCGAACTTGCCCCAGAGG
TTTACCAGCGAGAATTGGATTACCTGATGGCGCATGAATTTGCGCAATGCAGCGAAGATATTTTATGGCGTCGAACCAAA
CTGGGCCTCTACCTCACTCCAGAGCAAGTGCAAAGTGTGGAAAACTACATCGCAAAAAAGCATACCACCGCTCAGTCGCC
TCAATTGCAACAGGCGAGCTGA

Upstream 100 bases:

>100_bases
ACAAACGAAAATAATAGCTGATCTCATTCGAAACTTAAGTTATGCTCATTTAAGTTTCAAAATGCTCGTTCGAACAAAAA
ATAACATTAGGTCAGCTCAA

Downstream 100 bases:

>100_bases
TCTTTCCCTAAGATATTTGCACAATGATTAGAGTAGCCAAACTCCCCCAAGTCGCGTAACTTGGGGTGAGTTTCATTCAC
CAAAGCGACTCTTTGTTATG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKNNSSTPTSTLDILVVGGGINGAGIAADAAGRGLSVALFEAKDFASATSSASSKLIHGGLRYLEHYEFRLVSEALAERE
VLIKKAPHIAFPMRFRLPHRSYLRPAWMIRCGLFLYDHLGKRTTLPSSHKVNLAETGLLKEEMKIGFEYSDCWVDDARLT
LLNAISAKRNGAEVRNYCKVSKAERVDGLWKVTIEDQQNGEQFVRYAKALVNAAGPWVKQFYDDSLDGPSPRNIRLIKGS
HIVVPRVHPDPQAYILQNNDGRIVFVIPYLDKFSIVGTTDVEYTGDPRHVAISEQEVDYLIDIVNQHFVHQLSKQDVVWT
YSGVRPLCDDESDSPQAITRDYTIELEQELDQAPLLSIFGGKLTTYRKLAESAMRKLAPYFDHMGTPWTAQQTLPGGDFS
CTREQLAHALRQQYPWLSATLAYRYVCQYGSDARQLLAGAEEVSAMGIELAPEVYQRELDYLMAHEFAQCSEDILWRRTK
LGLYLTPEQVQSVENYIAKKHTTAQSPQLQQAS

Sequences:

>Translated_513_residues
MKNNSSTPTSTLDILVVGGGINGAGIAADAAGRGLSVALFEAKDFASATSSASSKLIHGGLRYLEHYEFRLVSEALAERE
VLIKKAPHIAFPMRFRLPHRSYLRPAWMIRCGLFLYDHLGKRTTLPSSHKVNLAETGLLKEEMKIGFEYSDCWVDDARLT
LLNAISAKRNGAEVRNYCKVSKAERVDGLWKVTIEDQQNGEQFVRYAKALVNAAGPWVKQFYDDSLDGPSPRNIRLIKGS
HIVVPRVHPDPQAYILQNNDGRIVFVIPYLDKFSIVGTTDVEYTGDPRHVAISEQEVDYLIDIVNQHFVHQLSKQDVVWT
YSGVRPLCDDESDSPQAITRDYTIELEQELDQAPLLSIFGGKLTTYRKLAESAMRKLAPYFDHMGTPWTAQQTLPGGDFS
CTREQLAHALRQQYPWLSATLAYRYVCQYGSDARQLLAGAEEVSAMGIELAPEVYQRELDYLMAHEFAQCSEDILWRRTK
LGLYLTPEQVQSVENYIAKKHTTAQSPQLQQAS
>Mature_513_residues
MKNNSSTPTSTLDILVVGGGINGAGIAADAAGRGLSVALFEAKDFASATSSASSKLIHGGLRYLEHYEFRLVSEALAERE
VLIKKAPHIAFPMRFRLPHRSYLRPAWMIRCGLFLYDHLGKRTTLPSSHKVNLAETGLLKEEMKIGFEYSDCWVDDARLT
LLNAISAKRNGAEVRNYCKVSKAERVDGLWKVTIEDQQNGEQFVRYAKALVNAAGPWVKQFYDDSLDGPSPRNIRLIKGS
HIVVPRVHPDPQAYILQNNDGRIVFVIPYLDKFSIVGTTDVEYTGDPRHVAISEQEVDYLIDIVNQHFVHQLSKQDVVWT
YSGVRPLCDDESDSPQAITRDYTIELEQELDQAPLLSIFGGKLTTYRKLAESAMRKLAPYFDHMGTPWTAQQTLPGGDFS
CTREQLAHALRQQYPWLSATLAYRYVCQYGSDARQLLAGAEEVSAMGIELAPEVYQRELDYLMAHEFAQCSEDILWRRTK
LGLYLTPEQVQSVENYIAKKHTTAQSPQLQQAS

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=512, Percent_Identity=32.2265625, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI285002231, Length=512, Percent_Identity=32.2265625, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI2367226, Length=465, Percent_Identity=60.8602150537634, Blast_Score=594, Evalue=1e-171,
Organism=Escherichia coli, GI1788574, Length=390, Percent_Identity=27.9487179487179, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17509253, Length=397, Percent_Identity=33.7531486146096, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI115534726, Length=508, Percent_Identity=30.7086614173228, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322036, Length=560, Percent_Identity=29.2857142857143, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI161077125, Length=390, Percent_Identity=34.1025641025641, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24653942, Length=390, Percent_Identity=34.1025641025641, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24653944, Length=390, Percent_Identity=34.1025641025641, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI20130025, Length=390, Percent_Identity=34.1025641025641, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24586295, Length=393, Percent_Identity=31.5521628498728, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19921278, Length=513, Percent_Identity=26.9005847953216, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI45550977, Length=377, Percent_Identity=23.6074270557029, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57680; Mature: 57680

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNSSTPTSTLDILVVGGGINGAGIAADAAGRGLSVALFEAKDFASATSSASSKLIHGG
CCCCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
LRYLEHYEFRLVSEALAEREVLIKKAPHIAFPMRFRLPHRSYLRPAWMIRCGLFLYDHLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCHHHHHHHHHHHHHHCC
KRTTLPSSHKVNLAETGLLKEEMKIGFEYSDCWVDDARLTLLNAISAKRNGAEVRNYCKV
CCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCEECCHHHHHHHHHHHCCCCHHHHHHHHH
SKAERVDGLWKVTIEDQQNGEQFVRYAKALVNAAGPWVKQFYDDSLDGPSPRNIRLIKGS
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEECC
HIVVPRVHPDPQAYILQNNDGRIVFVIPYLDKFSIVGTTDVEYTGDPRHVAISEQEVDYL
EEEEECCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCEECCCCCEEEECHHHHHHH
IDIVNQHFVHQLSKQDVVWTYSGVRPLCDDESDSPQAITRDYTIELEQELDQAPLLSIFG
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEECCCEEEEEHHHCCCCCCHHHHC
GKLTTYRKLAESAMRKLAPYFDHMGTPWTAQQTLPGGDFSCTREQLAHALRQQYPWLSAT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
LAYRYVCQYGSDARQLLAGAEEVSAMGIELAPEVYQRELDYLMAHEFAQCSEDILWRRTK
HHHHHHHHCCCHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYLTPEQVQSVENYIAKKHTTAQSPQLQQAS
CCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKNNSSTPTSTLDILVVGGGINGAGIAADAAGRGLSVALFEAKDFASATSSASSKLIHGG
CCCCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
LRYLEHYEFRLVSEALAEREVLIKKAPHIAFPMRFRLPHRSYLRPAWMIRCGLFLYDHLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCHHHHHHHHHHHHHHCC
KRTTLPSSHKVNLAETGLLKEEMKIGFEYSDCWVDDARLTLLNAISAKRNGAEVRNYCKV
CCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCEECCHHHHHHHHHHHCCCCHHHHHHHHH
SKAERVDGLWKVTIEDQQNGEQFVRYAKALVNAAGPWVKQFYDDSLDGPSPRNIRLIKGS
HHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEECC
HIVVPRVHPDPQAYILQNNDGRIVFVIPYLDKFSIVGTTDVEYTGDPRHVAISEQEVDYL
EEEEECCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCEECCCCCEEEECHHHHHHH
IDIVNQHFVHQLSKQDVVWTYSGVRPLCDDESDSPQAITRDYTIELEQELDQAPLLSIFG
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEECCCEEEEEHHHCCCCCCHHHHC
GKLTTYRKLAESAMRKLAPYFDHMGTPWTAQQTLPGGDFSCTREQLAHALRQQYPWLSAT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
LAYRYVCQYGSDARQLLAGAEEVSAMGIELAPEVYQRELDYLMAHEFAQCSEDILWRRTK
HHHHHHHHCCCHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYLTPEQVQSVENYIAKKHTTAQSPQLQQAS
CCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]