| Definition | Agrobacterium tumefaciens str. C58 plasmid Ti, complete sequence. |
|---|---|
| Accession | NC_003065 |
| Length | 214,233 |
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The map label for this gene is kduD [H]
Identifier: 16119876
GI number: 16119876
Start: 73926
End: 74696
Strand: Direct
Name: kduD [H]
Synonym: Atu6062
Alternate gene names: 16119876
Gene position: 73926-74696 (Clockwise)
Preceding gene: 16119875
Following gene: 16119877
Centisome position: 34.51
GC content: 60.31
Gene sequence:
>771_bases ATGACATATCCTTCGCAAATCCCCAACATCTCGAAGCTGTTTGACCTTTCCGGTCGGAGGGCCGTCATCACGGGCGGCGC TCGGGGGATCGGGCGCGCTATCGCTGACGGCTTCTTAGAAGTGGGAGCTGATGTCGTCTGCATCGACCGTGGATGGGAAA GCTCTGACCTCCCGGCCGATAACCGGCAGATTGTCACGGCCGATCTTAGCGACCGCAGCGACCTGAAGCGCGGATTCGAT GAAGCTGTGGAGCGACTGGGGGGCCAGATCGATGTCCTTGTCAACAACGCAGGCATCTGGGACGACACGCCGTCGCTCCA TATGGAGCTTGAGATGTGGGACAGGATCATCGAGGTCAATCTGACTGCGGCCTTCGCGCTGAGCAGGCATGCAGCCAGGC TGATGCTTCCCCGAGGCCGCGGACGAATAATAAACATTGGCTCCATCCGCAGTCTGAGGGGAGGCCACAATGCGGCTGCC TATGCAGCCAGCAAGGGAGGGATCGCCTTGCTCACTCAGACCTTGTCGAATGAATGGGCACCTTCAGGACTAAGGGTCAA TGCCATAGCGCCCGGCGCTATGGTCACCGTCCTGACTGAAAAGCTGCGCCACGATCCTGAAGTGGTCACCCGCTTCATCG AGCGCATCCCTGCCAGAAGATGGGGATCGCCCGCCGATGTGGCGGGCCTGGCGATCTTCCTGGCCAGCGACGCCTCCGAT TATGTCACTGGTGCAATCATCCCCTGCGACGGGGGGTTCCTTGCCGGTTAA
Upstream 100 bases:
>100_bases ATGTTCGGGATACGCACGTCTTTAAAGACCTGTCCGTCGATTACGGACTTGCAAGCGGCGTGCAGGGCCCGCGTTCGCAT CCCATGATGGTGGGCCTGTC
Downstream 100 bases:
>100_bases TCGAGCGAAACACGTTTTTCTGGAAAAGCAGAGACCGGACCAAAGGAAAACAGGAACTGATGAAGTGGTCTCAATCCACG CAGCGCTGGCTCGTTCGAGG
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 256; Mature: 255
Protein sequence:
>256_residues MTYPSQIPNISKLFDLSGRRAVITGGARGIGRAIADGFLEVGADVVCIDRGWESSDLPADNRQIVTADLSDRSDLKRGFD EAVERLGGQIDVLVNNAGIWDDTPSLHMELEMWDRIIEVNLTAAFALSRHAARLMLPRGRGRIINIGSIRSLRGGHNAAA YAASKGGIALLTQTLSNEWAPSGLRVNAIAPGAMVTVLTEKLRHDPEVVTRFIERIPARRWGSPADVAGLAIFLASDASD YVTGAIIPCDGGFLAG
Sequences:
>Translated_256_residues MTYPSQIPNISKLFDLSGRRAVITGGARGIGRAIADGFLEVGADVVCIDRGWESSDLPADNRQIVTADLSDRSDLKRGFD EAVERLGGQIDVLVNNAGIWDDTPSLHMELEMWDRIIEVNLTAAFALSRHAARLMLPRGRGRIINIGSIRSLRGGHNAAA YAASKGGIALLTQTLSNEWAPSGLRVNAIAPGAMVTVLTEKLRHDPEVVTRFIERIPARRWGSPADVAGLAIFLASDASD YVTGAIIPCDGGFLAG >Mature_255_residues TYPSQIPNISKLFDLSGRRAVITGGARGIGRAIADGFLEVGADVVCIDRGWESSDLPADNRQIVTADLSDRSDLKRGFDE AVERLGGQIDVLVNNAGIWDDTPSLHMELEMWDRIIEVNLTAAFALSRHAARLMLPRGRGRIINIGSIRSLRGGHNAAAY AASKGGIALLTQTLSNEWAPSGLRVNAIAPGAMVTVLTEKLRHDPEVVTRFIERIPARRWGSPADVAGLAIFLASDASDY VTGAIIPCDGGFLAG
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=34, Blast_Score=130, Evalue=2e-30, Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=34.5381526104418, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=30.1587301587302, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=32.2033898305085, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=31.0204081632653, Blast_Score=105, Evalue=6e-23, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=32.9411764705882, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=31.6964285714286, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=30.4878048780488, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=30.7377049180328, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=28.6384976525822, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=27.5471698113208, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=30.5882352941176, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.9156626506024, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI4504505, Length=219, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI209862901, Length=214, Percent_Identity=29.9065420560748, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI19923983, Length=214, Percent_Identity=29.9065420560748, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI226371731, Length=198, Percent_Identity=28.2828282828283, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503301, Length=191, Percent_Identity=27.2251308900524, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI109715829, Length=254, Percent_Identity=27.5590551181102, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=180, Percent_Identity=27.2222222222222, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=31.1224489795918, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=40.7258064516129, Blast_Score=169, Evalue=1e-43, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=38.4, Blast_Score=166, Evalue=1e-42, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=38.3399209486166, Blast_Score=159, Evalue=1e-40, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=35.2459016393443, Blast_Score=140, Evalue=8e-35, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=35.6, Blast_Score=124, Evalue=9e-30, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=34.1463414634146, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=33.739837398374, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=31.8548387096774, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.8775510204082, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=32.6359832635983, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=28.7449392712551, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=28.740157480315, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=27.1653543307087, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=27.9329608938547, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=36.5853658536585, Blast_Score=136, Evalue=8e-33, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=34.0163934426229, Blast_Score=134, Evalue=4e-32, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.4354838709677, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=32.156862745098, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=30.8300395256917, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=28.9156626506024, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=32.520325203252, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.9693486590038, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=29.6992481203008, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=28.0769230769231, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=31.3953488372093, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=30.8270676691729, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=28.1746031746032, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.8973384030418, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17561272, Length=252, Percent_Identity=29.7619047619048, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=29.296875, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=29.1187739463602, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.5862068965517, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=28.5171102661597, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=31.7829457364341, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=30.3846153846154, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71997099, Length=211, Percent_Identity=30.8056872037915, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=26.0536398467433, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=31.9444444444444, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.4681647940075, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=26.171875, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=30.0518134715026, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17564282, Length=161, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI86565303, Length=260, Percent_Identity=25, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203117, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193203115, Length=171, Percent_Identity=29.2397660818713, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=25.6704980842912, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=250, Percent_Identity=29.2, Blast_Score=88, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=23.7903225806452, Blast_Score=80, Evalue=3e-16, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=32.2709163346614, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.9236947791165, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI28571526, Length=243, Percent_Identity=31.2757201646091, Blast_Score=114, Evalue=7e-26, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=30.2788844621514, Blast_Score=114, Evalue=8e-26, Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=31.0204081632653, Blast_Score=112, Evalue=4e-25, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=31.8725099601594, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=29.8387096774194, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=29.2490118577075, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=32.2751322751323, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24584752, Length=207, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI221331218, Length=228, Percent_Identity=29.3859649122807, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=228, Percent_Identity=29.3859649122807, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584744, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28574402, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584748, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI161076933, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI281364892, Length=188, Percent_Identity=29.2553191489362, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=229, Percent_Identity=30.1310043668122, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665247, Length=229, Percent_Identity=30.1310043668122, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581726, Length=210, Percent_Identity=29.5238095238095, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007236, Length=240, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=29.2929292929293, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 27399; Mature: 27267
Theoretical pI: Translated: 6.13; Mature: 6.13
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYPSQIPNISKLFDLSGRRAVITGGARGIGRAIADGFLEVGADVVCIDRGWESSDLPAD CCCCCCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC NRQIVTADLSDRSDLKRGFDEAVERLGGQIDVLVNNAGIWDDTPSLHMELEMWDRIIEVN CCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHH LTAAFALSRHAARLMLPRGRGRIINIGSIRSLRGGHNAAAYAASKGGIALLTQTLSNEWA HHHHHHHHHHHHHEECCCCCCCEEEECCCCCCCCCCCHHEEEECCCCCEEEEEHHCCCCC PSGLRVNAIAPGAMVTVLTEKLRHDPEVVTRFIERIPARRWGSPADVAGLAIFLASDASD CCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCHHCCCCCCHHHHEEEEEECCCCC YVTGAIIPCDGGFLAG HHEEEEEECCCCCCCC >Mature Secondary Structure TYPSQIPNISKLFDLSGRRAVITGGARGIGRAIADGFLEVGADVVCIDRGWESSDLPAD CCCCCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC NRQIVTADLSDRSDLKRGFDEAVERLGGQIDVLVNNAGIWDDTPSLHMELEMWDRIIEVN CCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHH LTAAFALSRHAARLMLPRGRGRIINIGSIRSLRGGHNAAAYAASKGGIALLTQTLSNEWA HHHHHHHHHHHHHEECCCCCCCEEEECCCCCCCCCCCHHEEEECCCCCEEEEEHHCCCCC PSGLRVNAIAPGAMVTVLTEKLRHDPEVVTRFIERIPARRWGSPADVAGLAIFLASDASD CCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCHHCCCCCCHHHHEEEEEECCCCC YVTGAIIPCDGGFLAG HHEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8760912; 9384377 [H]