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The map label for this gene is dnaN [H]

Identifier: 160902631

GI number: 160902631

Start: 1256316

End: 1257428

Strand: Direct

Name: dnaN [H]

Synonym: Pmob_1171

Alternate gene names: 160902631

Gene position: 1256316-1257428 (Clockwise)

Preceding gene: 160902630

Following gene: 160902632

Centisome position: 57.91

GC content: 34.5

Gene sequence:

>1113_bases
ATGTCTTTTGAAATAGATACAAGGGTTTTAAAAAATGCTGTTCAATTAACCAGTAATGCTGTTTCAAGAAAAACAGCTAA
CCCTATTTTGAAAGGAATAAAATTGGCTGTAGAAGACGATGAGTTACACATTTATGCTACAGATTTGCAGACCGGTTTTC
ACAAATGGCTGAAGGTTAAAGATAGTGATGAAAACTTTTCTACAGTGGTGGAACAGACGATATTCTTGGAAATTCTATCG
AATCTCACTTCTGACACAATTACGATCACTTTGGATGGAGTCTTGAAGATTTCAGGTGGCAATTCTGTATTTCGATTACC
TACCATGGACCCTGATGAATTTCCTTCTCTTGCTTTCGAGGTTACAGGGAATTCAATTTTGTTAGATAGAACAATTATTA
CTAATATGATCGATAAGGTTGTTTTTTGTGCTTTAAAAGATTCTTCTTCCCTTTCGCGCAATTTAAATGCCGTTTACTGG
GATTTTAGACAAGGTGGCTTTTTGAACTTAGTCGCAACCGATTCATATAGATTAGCCCTTTCTGAAAGTAAGTTGGAAGA
TGATAATATTCTTTCACCATTCCTTTTATCCCTAAAAAGTATGGATGAATTAAAAACGATACTTTCTTCCGCAAAAACGG
AGAAGGTAAGAGTGGTCCAAAGTGGTTCTCAAATTCTCTTTGATTTTGAAGAAGATAATAACCAGCTGATTTATAACGTT
ATAGATGCTGAATTTCCTAATTATTTGAGTATAATTCCCGAGAGTTTTATCACAAAGATCAAGGCTAAGACCTCAGAATT
TTTGGCTATTATGAAAAGGATGTCTATAACAGCCGGAAGTGAGGAATATACTTTATTAAATATTGAAGATGGAAGAATAC
AGTTTTATGCGAGTTCTCCGGATGTTGGTGAAGCAAAAGAAGAGATTGATGTCGAACAAGAGGGTAAAAATATTGAGATT
GCTTATTCCCCAAGATATTTCAGGGAAGCGTTAGAAAGAATAGAGACAGTGGAATTTGAATTTGATATATCCGATGAGGA
AAAACCTACCATTTTAAAACCTTTGGAAGACAACAGTTACATGTTCATAATAATGCCAAAAAGGAAAAGTTGA

Upstream 100 bases:

>100_bases
AAACGAATAATTTTTAATTAATTTATTCTTGCTTTAAATTTTTTTTTAGTGTAAAATTGAGATAGTGAAACCCTAATTCT
TCCAAAGGGAGGAAAACTTG

Downstream 100 bases:

>100_bases
AACATGTTAAAAATTGGGTTTGGTTACGATGTTCATCCTTTTGCTGAAAATAGAAGATTAATATTGGGTGGAGTTGTAAT
TAATCATCCAAAAGGTTATG

Product: DNA polymerase III subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSFEIDTRVLKNAVQLTSNAVSRKTANPILKGIKLAVEDDELHIYATDLQTGFHKWLKVKDSDENFSTVVEQTIFLEILS
NLTSDTITITLDGVLKISGGNSVFRLPTMDPDEFPSLAFEVTGNSILLDRTIITNMIDKVVFCALKDSSSLSRNLNAVYW
DFRQGGFLNLVATDSYRLALSESKLEDDNILSPFLLSLKSMDELKTILSSAKTEKVRVVQSGSQILFDFEEDNNQLIYNV
IDAEFPNYLSIIPESFITKIKAKTSEFLAIMKRMSITAGSEEYTLLNIEDGRIQFYASSPDVGEAKEEIDVEQEGKNIEI
AYSPRYFREALERIETVEFEFDISDEEKPTILKPLEDNSYMFIIMPKRKS

Sequences:

>Translated_370_residues
MSFEIDTRVLKNAVQLTSNAVSRKTANPILKGIKLAVEDDELHIYATDLQTGFHKWLKVKDSDENFSTVVEQTIFLEILS
NLTSDTITITLDGVLKISGGNSVFRLPTMDPDEFPSLAFEVTGNSILLDRTIITNMIDKVVFCALKDSSSLSRNLNAVYW
DFRQGGFLNLVATDSYRLALSESKLEDDNILSPFLLSLKSMDELKTILSSAKTEKVRVVQSGSQILFDFEEDNNQLIYNV
IDAEFPNYLSIIPESFITKIKAKTSEFLAIMKRMSITAGSEEYTLLNIEDGRIQFYASSPDVGEAKEEIDVEQEGKNIEI
AYSPRYFREALERIETVEFEFDISDEEKPTILKPLEDNSYMFIIMPKRKS
>Mature_369_residues
SFEIDTRVLKNAVQLTSNAVSRKTANPILKGIKLAVEDDELHIYATDLQTGFHKWLKVKDSDENFSTVVEQTIFLEILSN
LTSDTITITLDGVLKISGGNSVFRLPTMDPDEFPSLAFEVTGNSILLDRTIITNMIDKVVFCALKDSSSLSRNLNAVYWD
FRQGGFLNLVATDSYRLALSESKLEDDNILSPFLLSLKSMDELKTILSSAKTEKVRVVQSGSQILFDFEEDNNQLIYNVI
DAEFPNYLSIIPESFITKIKAKTSEFLAIMKRMSITAGSEEYTLLNIEDGRIQFYASSPDVGEAKEEIDVEQEGKNIEIA
YSPRYFREALERIETVEFEFDISDEEKPTILKPLEDNSYMFIIMPKRKS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790136, Length=374, Percent_Identity=22.4598930481283, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001001
- InterPro:   IPR022635
- InterPro:   IPR022637
- InterPro:   IPR022634 [H]

Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41911; Mature: 41780

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEIDTRVLKNAVQLTSNAVSRKTANPILKGIKLAVEDDELHIYATDLQTGFHKWLKVK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEEEEECHHHHHHHHEEEE
DSDENFSTVVEQTIFLEILSNLTSDTITITLDGVLKISGGNSVFRLPTMDPDEFPSLAFE
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEECCCCCCCCCCCEEEE
VTGNSILLDRTIITNMIDKVVFCALKDSSSLSRNLNAVYWDFRQGGFLNLVATDSYRLAL
ECCCEEEEHHHHHHHHHHHHEEEEECCCCHHHCCCCEEEEECCCCCEEEEEEECCEEEEE
SESKLEDDNILSPFLLSLKSMDELKTILSSAKTEKVRVVQSGSQILFDFEEDNNQLIYNV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCEEEEEE
IDAEFPNYLSIIPESFITKIKAKTSEFLAIMKRMSITAGSEEYTLLNIEDGRIQFYASSP
ECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCC
DVGEAKEEIDVEQEGKNIEIAYSPRYFREALERIETVEFEFDISDEEKPTILKPLEDNSY
CCCCHHHHCCHHHCCCEEEEEECCHHHHHHHHHHHEEEEEEECCCCCCCCEEECCCCCCE
MFIIMPKRKS
EEEEEECCCC
>Mature Secondary Structure 
SFEIDTRVLKNAVQLTSNAVSRKTANPILKGIKLAVEDDELHIYATDLQTGFHKWLKVK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEEEEECHHHHHHHHEEEE
DSDENFSTVVEQTIFLEILSNLTSDTITITLDGVLKISGGNSVFRLPTMDPDEFPSLAFE
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEECCCCCCCCCCCEEEE
VTGNSILLDRTIITNMIDKVVFCALKDSSSLSRNLNAVYWDFRQGGFLNLVATDSYRLAL
ECCCEEEEHHHHHHHHHHHHEEEEECCCCHHHCCCCEEEEECCCCCEEEEEEECCEEEEE
SESKLEDDNILSPFLLSLKSMDELKTILSSAKTEKVRVVQSGSQILFDFEEDNNQLIYNV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCEEEEEE
IDAEFPNYLSIIPESFITKIKAKTSEFLAIMKRMSITAGSEEYTLLNIEDGRIQFYASSP
ECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCC
DVGEAKEEIDVEQEGKNIEIAYSPRYFREALERIETVEFEFDISDEEKPTILKPLEDNSY
CCCCHHHHCCHHHCCCEEEEEECCHHHHHHHHHHHEEEEEEECCCCCCCCEEECCCCCCE
MFIIMPKRKS
EEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2987847; 7584024; 9384377; 2846289 [H]