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The map label for this gene is clpB [H]

Identifier: 160901847

GI number: 160901847

Start: 389153

End: 391645

Strand: Direct

Name: clpB [H]

Synonym: Pmob_0363

Alternate gene names: 160901847

Gene position: 389153-391645 (Clockwise)

Preceding gene: 160901837

Following gene: 160901848

Centisome position: 17.94

GC content: 36.18

Gene sequence:

>2493_bases
ATGTTTGATAATTTTACTGAAAGAGCTGCGAAAGTTTTTATTGAGGCTCAAAATGAAGCAAAACAGATGGGACATCCCTA
TGTGGGGACAGAACACATTTTATTAGGATTGTTGAAAGTTGGAGGAGGCCATTTAGATACCGTATTTGAAGAATTTAATT
TGTACTATAATTCTATAAAGATGGAAATAACAAATGTTGTTGGTACGAATTCAACACAGGGAATAATAGGTTCTCCACAA
CCAACTCCTAGAGCAAAAAGAATATTAGAGTTGGCATATGATGAATCTGAGCTTATGGGTTTCAATAAGATAGATGCGGA
ACATCTTCTTTTAGGCATTTGTAGGGAAGCCGAAGGGATAGCCTCTCATATATTGAAACGTTCAGGAATAAATCTAACTT
TGATGAGAAAAGAATTAACGGATATGATGATTAAGGGTAGATCAACCGGGAGGATGGAGATTGCTAAAACTGAAGAGTTA
GAAGAAAGAAAGCGTCAAAAACAGAATGCGCTAAAACAGCTCGAAGAATACGGAACTGATTTAACTGCTCAAGCTGAGAA
CCGCAAACTGGATCCTATAATTGGAAGAGAAATAGAAATTAATCGCATAATGGAAATATTGGCGAGACGAAAAAAGAACA
ATCCTGTTTTGATTGGTGAGGCAGGTGTAGGTAAAAGTGCAGTGGTCGAGGGTCTGGCACAAAGAATTGTTGAAGGCCGA
GTACCTGAAATATTAAAAAATAAAACTATTTTTTCCTTAGATATTACCTCAATAGTAGCGGGAACAAAATATCGTGGAGA
ATTTGAGAAACGAATGAAAAAATTGATGCAGATATTACAAAAGACTGAAGATATTATTCTTTTTATCGACGAATTGCATA
TGATTGTAGAGGCTGGTGCGGCTGAAGGTTCTTCCATGGACGCAGCAAATGTTTTAAAACCGGCTTTAGCAAACGGAGAA
ATAACCGTAATAGGGTCCACCACAGCGAATGAGTACAGGAAATTCATCGAAAAAGATCCAGCCCTCGAAAGACGTTTCCA
AAAGATATATGTAACTGAACCAACTATCGAAGAAACTATAAATATATTATCTGGAATCAAATTCAAATACGAGGAACATC
ACAAAGTCAAATATAACCATGGTGCAATTCAATCAGCTGTTCAACTCTCGGTAAGGTATATTACAGATAGACACCTACCA
GATAAAGCGATAGATGTTATCGATGAAGCTGGAGCTAAAGCCCGTTTAAGTGCTCTAACGCTCCCTGATAAATTAAAAAT
TCAATATGAAAAGATTGCAGATATCGAAAGTAAAAGAAACGATCCCAATTCTAAAGAAAACGTTGAAGAAAAACTAAAAA
AGATGAAAGAAAAGTATGAAGAAGAATATTCAAAATGGAGATCTGAAGCAGAAAATAAAATAATTCAAATAACCGAAGAG
GATATAGCTGAAATAATATCTAATTGGACTGGTGTTCCGCTCAGACAGTTGCGTGCAGAAGAGATGGAAAAATTATTGAA
TTTAGAGGCTGTCTTACACGAACGAGTGGTAGGGCAGGATGAAGCAATAAAATCAGTTGCAAAAGCTATAAGAAGAGCGC
GAAGTGGATTAAAAGACCCTAGAAGACCAACAGGTGTATTTATGTTTTTAGGCCCGACCGGTGTTGGGAAAACTGAACTA
GCTAAGACTCTAGCAACTTATCTTTTTGGAAACGAAACGCATTTAGTAAGAATAGATATGAGTGAATACATGGAAAAATT
CAGTGTCTCCAGACTTGTGGGTGCTCCCCCGGGGTATGTCGGCTACGATGAAGGTGGGCAATTAACAGAAATAGTAAGAA
GAAGACCTTATTCCGTAATTTTGCTGGACGAAATAGAAAAAGCTCATACAGACGTATACAATATTTTGTTGCAAATAATG
GATGAAGGAAGATTGACTGATTCTCAAGGGAGAACGGTTGACTTTAGAAACACAATAATTATTATGACCTCTAACCTCGG
TTCTGAACAGATTAGCAAAACTAAAAGAAGCTTAGGTTTTGTAGAAGAAGGTACAATAGAAAGCGAATACAAAGATATCA
AAGAACAGGTGATGTCTGCGGTAAAGGCGGCATTCAAACCTGAATTCATAAACAGATTAGATGATGTCATTGTATTTCAC
CCGCTCACTAAAAATCAACTTAAAAATATTATATCTATTCAACTTAGCGACCTAAAAAGCCGATTGGAAGAAAGGAATCT
TACATTATCCGTGAAAGAAAGTGCCATTGATTTCTTACTGGAAAAGGGTTATGATTCTGTCTTTGGAGCTAGGCCATTGA
AAAGAGCTATACAAAGATATATTGAAGATCCTTTGTCCGAAGAATTATTAAAAGGAAAATACGAAGAAGGAGATAAGATA
TTAGTTACTCACCAAAAATCTAAAGAAAGTCTTTCTTTTAGAAGAGTTCCTAAGGATAAGAAGCAAATGGAAAAGAAAGT
GGTCAATAGTTGA

Upstream 100 bases:

>100_bases
AAGTATAAAAAATGGCTAATAATAATATTTCTATATAAAGCGACGCGAACTAATCGGTAGTTTCTGTTGCTTAGATGTAC
GGTAAAGGAGGAGAGTAGAC

Downstream 100 bases:

>100_bases
GAAAATCTGAGAAACACTATGTCTGCAGTAATTGTGGCTATGAATCCGATAAATGGTTCGCAAAATGTCCTATGTGTAAT
GAATTAGAATCCGCGGTAGA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 830; Mature: 830

Protein sequence:

>830_residues
MFDNFTERAAKVFIEAQNEAKQMGHPYVGTEHILLGLLKVGGGHLDTVFEEFNLYYNSIKMEITNVVGTNSTQGIIGSPQ
PTPRAKRILELAYDESELMGFNKIDAEHLLLGICREAEGIASHILKRSGINLTLMRKELTDMMIKGRSTGRMEIAKTEEL
EERKRQKQNALKQLEEYGTDLTAQAENRKLDPIIGREIEINRIMEILARRKKNNPVLIGEAGVGKSAVVEGLAQRIVEGR
VPEILKNKTIFSLDITSIVAGTKYRGEFEKRMKKLMQILQKTEDIILFIDELHMIVEAGAAEGSSMDAANVLKPALANGE
ITVIGSTTANEYRKFIEKDPALERRFQKIYVTEPTIEETINILSGIKFKYEEHHKVKYNHGAIQSAVQLSVRYITDRHLP
DKAIDVIDEAGAKARLSALTLPDKLKIQYEKIADIESKRNDPNSKENVEEKLKKMKEKYEEEYSKWRSEAENKIIQITEE
DIAEIISNWTGVPLRQLRAEEMEKLLNLEAVLHERVVGQDEAIKSVAKAIRRARSGLKDPRRPTGVFMFLGPTGVGKTEL
AKTLATYLFGNETHLVRIDMSEYMEKFSVSRLVGAPPGYVGYDEGGQLTEIVRRRPYSVILLDEIEKAHTDVYNILLQIM
DEGRLTDSQGRTVDFRNTIIIMTSNLGSEQISKTKRSLGFVEEGTIESEYKDIKEQVMSAVKAAFKPEFINRLDDVIVFH
PLTKNQLKNIISIQLSDLKSRLEERNLTLSVKESAIDFLLEKGYDSVFGARPLKRAIQRYIEDPLSEELLKGKYEEGDKI
LVTHQKSKESLSFRRVPKDKKQMEKKVVNS

Sequences:

>Translated_830_residues
MFDNFTERAAKVFIEAQNEAKQMGHPYVGTEHILLGLLKVGGGHLDTVFEEFNLYYNSIKMEITNVVGTNSTQGIIGSPQ
PTPRAKRILELAYDESELMGFNKIDAEHLLLGICREAEGIASHILKRSGINLTLMRKELTDMMIKGRSTGRMEIAKTEEL
EERKRQKQNALKQLEEYGTDLTAQAENRKLDPIIGREIEINRIMEILARRKKNNPVLIGEAGVGKSAVVEGLAQRIVEGR
VPEILKNKTIFSLDITSIVAGTKYRGEFEKRMKKLMQILQKTEDIILFIDELHMIVEAGAAEGSSMDAANVLKPALANGE
ITVIGSTTANEYRKFIEKDPALERRFQKIYVTEPTIEETINILSGIKFKYEEHHKVKYNHGAIQSAVQLSVRYITDRHLP
DKAIDVIDEAGAKARLSALTLPDKLKIQYEKIADIESKRNDPNSKENVEEKLKKMKEKYEEEYSKWRSEAENKIIQITEE
DIAEIISNWTGVPLRQLRAEEMEKLLNLEAVLHERVVGQDEAIKSVAKAIRRARSGLKDPRRPTGVFMFLGPTGVGKTEL
AKTLATYLFGNETHLVRIDMSEYMEKFSVSRLVGAPPGYVGYDEGGQLTEIVRRRPYSVILLDEIEKAHTDVYNILLQIM
DEGRLTDSQGRTVDFRNTIIIMTSNLGSEQISKTKRSLGFVEEGTIESEYKDIKEQVMSAVKAAFKPEFINRLDDVIVFH
PLTKNQLKNIISIQLSDLKSRLEERNLTLSVKESAIDFLLEKGYDSVFGARPLKRAIQRYIEDPLSEELLKGKYEEGDKI
LVTHQKSKESLSFRRVPKDKKQMEKKVVNS
>Mature_830_residues
MFDNFTERAAKVFIEAQNEAKQMGHPYVGTEHILLGLLKVGGGHLDTVFEEFNLYYNSIKMEITNVVGTNSTQGIIGSPQ
PTPRAKRILELAYDESELMGFNKIDAEHLLLGICREAEGIASHILKRSGINLTLMRKELTDMMIKGRSTGRMEIAKTEEL
EERKRQKQNALKQLEEYGTDLTAQAENRKLDPIIGREIEINRIMEILARRKKNNPVLIGEAGVGKSAVVEGLAQRIVEGR
VPEILKNKTIFSLDITSIVAGTKYRGEFEKRMKKLMQILQKTEDIILFIDELHMIVEAGAAEGSSMDAANVLKPALANGE
ITVIGSTTANEYRKFIEKDPALERRFQKIYVTEPTIEETINILSGIKFKYEEHHKVKYNHGAIQSAVQLSVRYITDRHLP
DKAIDVIDEAGAKARLSALTLPDKLKIQYEKIADIESKRNDPNSKENVEEKLKKMKEKYEEEYSKWRSEAENKIIQITEE
DIAEIISNWTGVPLRQLRAEEMEKLLNLEAVLHERVVGQDEAIKSVAKAIRRARSGLKDPRRPTGVFMFLGPTGVGKTEL
AKTLATYLFGNETHLVRIDMSEYMEKFSVSRLVGAPPGYVGYDEGGQLTEIVRRRPYSVILLDEIEKAHTDVYNILLQIM
DEGRLTDSQGRTVDFRNTIIIMTSNLGSEQISKTKRSLGFVEEGTIESEYKDIKEQVMSAVKAAFKPEFINRLDDVIVFH
PLTKNQLKNIISIQLSDLKSRLEERNLTLSVKESAIDFLLEKGYDSVFGARPLKRAIQRYIEDPLSEELLKGKYEEGDKI
LVTHQKSKESLSFRRVPKDKKQMEKKVVNS

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=341, Percent_Identity=36.3636363636364, Blast_Score=214, Evalue=3e-55,
Organism=Escherichia coli, GI1787109, Length=799, Percent_Identity=39.6745932415519, Blast_Score=577, Evalue=1e-165,
Organism=Escherichia coli, GI1788943, Length=325, Percent_Identity=57.5384615384615, Blast_Score=401, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320464, Length=704, Percent_Identity=44.6022727272727, Blast_Score=582, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6323002, Length=887, Percent_Identity=35.6257046223224, Blast_Score=515, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94214; Mature: 94214

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDNFTERAAKVFIEAQNEAKQMGHPYVGTEHILLGLLKVGGGHLDTVFEEFNLYYNSIK
CCCCHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MEITNVVGTNSTQGIIGSPQPTPRAKRILELAYDESELMGFNKIDAEHLLLGICREAEGI
EEEEEHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHH
ASHILKRSGINLTLMRKELTDMMIKGRSTGRMEIAKTEELEERKRQKQNALKQLEEYGTD
HHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
LTAQAENRKLDPIIGREIEINRIMEILARRKKNNPVLIGEAGVGKSAVVEGLAQRIVEGR
CEECCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCC
VPEILKNKTIFSLDITSIVAGTKYRGEFEKRMKKLMQILQKTEDIILFIDELHMIVEAGA
CHHHHCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHCC
AEGSSMDAANVLKPALANGEITVIGSTTANEYRKFIEKDPALERRFQKIYVTEPTIEETI
CCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCHHHHHHHHEEEECCCCHHHHH
NILSGIKFKYEEHHKVKYNHGAIQSAVQLSVRYITDRHLPDKAIDVIDEAGAKARLSALT
HHHHCCCEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCC
LPDKLKIQYEKIADIESKRNDPNSKENVEEKLKKMKEKYEEEYSKWRSEAENKIIQITEE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHH
DIAEIISNWTGVPLRQLRAEEMEKLLNLEAVLHERVVGQDEAIKSVAKAIRRARSGLKDP
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
RRPTGVFMFLGPTGVGKTELAKTLATYLFGNETHLVRIDMSEYMEKFSVSRLVGAPPGYV
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCC
GYDEGGQLTEIVRRRPYSVILLDEIEKAHTDVYNILLQIMDEGRLTDSQGRTVDFRNTII
CCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEE
IMTSNLGSEQISKTKRSLGFVEEGTIESEYKDIKEQVMSAVKAAFKPEFINRLDDVIVFH
EEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEC
PLTKNQLKNIISIQLSDLKSRLEERNLTLSVKESAIDFLLEKGYDSVFGARPLKRAIQRY
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
IEDPLSEELLKGKYEEGDKILVTHQKSKESLSFRRVPKDKKQMEKKVVNS
HHCCHHHHHHCCCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MFDNFTERAAKVFIEAQNEAKQMGHPYVGTEHILLGLLKVGGGHLDTVFEEFNLYYNSIK
CCCCHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MEITNVVGTNSTQGIIGSPQPTPRAKRILELAYDESELMGFNKIDAEHLLLGICREAEGI
EEEEEHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHH
ASHILKRSGINLTLMRKELTDMMIKGRSTGRMEIAKTEELEERKRQKQNALKQLEEYGTD
HHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
LTAQAENRKLDPIIGREIEINRIMEILARRKKNNPVLIGEAGVGKSAVVEGLAQRIVEGR
CEECCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCC
VPEILKNKTIFSLDITSIVAGTKYRGEFEKRMKKLMQILQKTEDIILFIDELHMIVEAGA
CHHHHCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHCC
AEGSSMDAANVLKPALANGEITVIGSTTANEYRKFIEKDPALERRFQKIYVTEPTIEETI
CCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCHHHHHHHHEEEECCCCHHHHH
NILSGIKFKYEEHHKVKYNHGAIQSAVQLSVRYITDRHLPDKAIDVIDEAGAKARLSALT
HHHHCCCEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCC
LPDKLKIQYEKIADIESKRNDPNSKENVEEKLKKMKEKYEEEYSKWRSEAENKIIQITEE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHH
DIAEIISNWTGVPLRQLRAEEMEKLLNLEAVLHERVVGQDEAIKSVAKAIRRARSGLKDP
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
RRPTGVFMFLGPTGVGKTELAKTLATYLFGNETHLVRIDMSEYMEKFSVSRLVGAPPGYV
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCC
GYDEGGQLTEIVRRRPYSVILLDEIEKAHTDVYNILLQIMDEGRLTDSQGRTVDFRNTII
CCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEE
IMTSNLGSEQISKTKRSLGFVEEGTIESEYKDIKEQVMSAVKAAFKPEFINRLDDVIVFH
EEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEC
PLTKNQLKNIISIQLSDLKSRLEERNLTLSVKESAIDFLLEKGYDSVFGARPLKRAIQRY
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
IEDPLSEELLKGKYEEGDKILVTHQKSKESLSFRRVPKDKKQMEKKVVNS
HHCCHHHHHHCCCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]