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The map label for this gene is livH [H]

Identifier: 160901752

GI number: 160901752

Start: 283001

End: 283915

Strand: Direct

Name: livH [H]

Synonym: Pmob_0266

Alternate gene names: 160901752

Gene position: 283001-283915 (Clockwise)

Preceding gene: 160901751

Following gene: 160901753

Centisome position: 13.04

GC content: 38.47

Gene sequence:

>915_bases
TTGACTATCCAAATGTTCTTTCAACATCTAGCAAATGCCATCTCTCTTGGCAGCATATACGCACTTATTGCCATAGGTTA
TACTATGGTTTATGGGATACTCAATTTAATAAATTTTGCTCATGGTGACATTTTTACTTTTAGCATGTATTTTGCTTTTT
ATGCAGTTACTCTCTTTTTATTTCCATGGTGGGCAGCTTTTATTTTTGCGATTGTTTTAACGACTCTACTAGGTGCTACA
ATCGAACGAGTTGCTTACAGACCATTAAGAAAGGCTAATGCCCCCAAGATCTCAGCATTAATCACAGCTATTGGTGTATC
GTTCTTCCTACAAAACTTCGCAATAGTTGTCTTTGGTGGAAGAGCAAAATCATTCAATCCCCAATTAGGAGTTTACCCAA
CACAATTTGCACAAGTACTAACTTTTGGAGATGTAAGGATACCTTTATTAACCTTCATTATTATAGGTGTTTCTATTCTT
GCACTTTTTGTATTGGTTTGGATAGTTTATAGAACAAAAGCCGGCATGGCGATGAGGGCAGTTTCTAAAGATGTTACTGC
AGCAAAATTAATGGGCATAAACACCGACAGAACTATTTCTCAAACATTTATGTTGGGGTCCGCCTTAGCAGCTGTGGGAG
GTATTCTTTGGGCTATGAAATACCCTCAAATCTATCCTTATACCGGCATGATCCCCGGTTTAAAGGCATTTATAGCTGCA
GTTGTCGGAGGAATTGGAAGTATTCCAGGAGCTATGCTTGGAGGTTTTATTTTAGGGGTTGCCGAAATAATGATAGTCGC
ATTCTTACCCGCTTTGGCAGGATATAGAGACGCTATTGCTTATATTATTTTGATAGTTATTCTTTTAGTAAAACCAAACG
GGCTTCTCGGTGTGGAAATAGGGGAGAAGGTGTGA

Upstream 100 bases:

>100_bases
GTACCGTTATAAAACCCAGGATGTAATATTTAACTATATTAAAGCCATCTCACAAAATGAGATGGCTATACTTTCTTGGA
TCCAGAAAGGGGGCTCATAA

Downstream 100 bases:

>100_bases
ATATGGAAAAAACGCTATCTTTTAAGACTAAATTCTTTTTGACAATTCTTTTTATATTGGCAATCTTTCTATTACTGTTG
ACAGCTAATAACAAAGCTAG

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTIQMFFQHLANAISLGSIYALIAIGYTMVYGILNLINFAHGDIFTFSMYFAFYAVTLFLFPWWAAFIFAIVLTTLLGAT
IERVAYRPLRKANAPKISALITAIGVSFFLQNFAIVVFGGRAKSFNPQLGVYPTQFAQVLTFGDVRIPLLTFIIIGVSIL
ALFVLVWIVYRTKAGMAMRAVSKDVTAAKLMGINTDRTISQTFMLGSALAAVGGILWAMKYPQIYPYTGMIPGLKAFIAA
VVGGIGSIPGAMLGGFILGVAEIMIVAFLPALAGYRDAIAYIILIVILLVKPNGLLGVEIGEKV

Sequences:

>Translated_304_residues
MTIQMFFQHLANAISLGSIYALIAIGYTMVYGILNLINFAHGDIFTFSMYFAFYAVTLFLFPWWAAFIFAIVLTTLLGAT
IERVAYRPLRKANAPKISALITAIGVSFFLQNFAIVVFGGRAKSFNPQLGVYPTQFAQVLTFGDVRIPLLTFIIIGVSIL
ALFVLVWIVYRTKAGMAMRAVSKDVTAAKLMGINTDRTISQTFMLGSALAAVGGILWAMKYPQIYPYTGMIPGLKAFIAA
VVGGIGSIPGAMLGGFILGVAEIMIVAFLPALAGYRDAIAYIILIVILLVKPNGLLGVEIGEKV
>Mature_303_residues
TIQMFFQHLANAISLGSIYALIAIGYTMVYGILNLINFAHGDIFTFSMYFAFYAVTLFLFPWWAAFIFAIVLTTLLGATI
ERVAYRPLRKANAPKISALITAIGVSFFLQNFAIVVFGGRAKSFNPQLGVYPTQFAQVLTFGDVRIPLLTFIIIGVSILA
LFVLVWIVYRTKAGMAMRAVSKDVTAAKLMGINTDRTISQTFMLGSALAAVGGILWAMKYPQIYPYTGMIPGLKAFIAAV
VGGIGSIPGAMLGGFILGVAEIMIVAFLPALAGYRDAIAYIILIVILLVKPNGLLGVEIGEKV

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=312, Percent_Identity=44.2307692307692, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32877; Mature: 32746

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQMFFQHLANAISLGSIYALIAIGYTMVYGILNLINFAHGDIFTFSMYFAFYAVTLFL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FPWWAAFIFAIVLTTLLGATIERVAYRPLRKANAPKISALITAIGVSFFLQNFAIVVFGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECC
RAKSFNPQLGVYPTQFAQVLTFGDVRIPLLTFIIIGVSILALFVLVWIVYRTKAGMAMRA
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSKDVTAAKLMGINTDRTISQTFMLGSALAAVGGILWAMKYPQIYPYTGMIPGLKAFIAA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
VVGGIGSIPGAMLGGFILGVAEIMIVAFLPALAGYRDAIAYIILIVILLVKPNGLLGVEI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GEKV
CCCC
>Mature Secondary Structure 
TIQMFFQHLANAISLGSIYALIAIGYTMVYGILNLINFAHGDIFTFSMYFAFYAVTLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]