Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 160877556

GI number: 160877556

Start: 5264063

End: 5266216

Strand: Reverse

Name: atoS [H]

Synonym: Sbal195_4455

Alternate gene names: 160877556

Gene position: 5266216-5264063 (Counterclockwise)

Preceding gene: 160877557

Following gene: 160877553

Centisome position: 98.48

GC content: 48.75

Gene sequence:

>2154_bases
GTGTCATTCTTCACTCACTTTTTTGGTGTCAGTTGGCAGCAAATGCAGGCCAAGGTGCGCTATCGCATATTAATCCTGAC
ATTACTGCCTATTCTGCTGACACTGGTGAGTTTAGTGTTTATCACTATTTACTGGAATATCAGTTACACAGGTAAGCAGC
TGTTTATGAAGGTTAAAGCTGACTTGTCTGTTGCCGAAAATACCTTGCAGCAAGTGCAAGTTCGCCAAGAAAAGCAACTC
GAACGTGTGGTAACGTCTTGGACCTTTCAAAATGATTTTAGGCCACTTTTCAGTGGTAAAGAATTAACTGGTGAAGTCAT
CCACAGAGCCAGTCTCGACGCATTTCTCCTCGAACAGAAAAAACAACTTAACCTCGATTATCTGCGTCTCGTCACTGTCG
CCGAAGCGGCCGCTGACCCTGATTTACGGCAGATCCTCCCAAAGATAAACGGGTTATTACCTTATTCCGGCTTGATGGTG
TTGCCGCCCGAACGTTTATCACGCATCGACCCAGAATTAGCGGTCACAGCGAGCATCCCGATAGTCGCGACTTTGCGGGC
GCAGAGCCCGACAAAAACCGTTGAAGAACGCGGTTTATTGAGCCGTAGTCTACTGCCCGTGCCTGATATGCAAGGTAAAG
TGGCGTGGTATCTGGATGGCGGGATTCTATTCAATCGTGACATTCGGATTGTCGACCACATTCGTGATCTGGTGTACGAC
AAGGGCACCTTGCCCGAGCGCTCCATCGGCACTGTAACCATCTTCTTAGATAACATCCGTATCTCCACTAACGTGCCGCT
GCACTTTTATCCGACGGGCAACGAGACGCAAGGTCGCGCGCTGGGCAGTTTAGTGTCGGAGGAAGTTAAGGAGAAAGTGT
TAACCCAAGGCGAGCAATGGGTCGATCGTGCCTTCGTGTTTAACGATTGGTTTATATCCGCTTATGCTCCCTTGGAAGAT
ATTCGTGGCCAGCGTGTTGGCATGATCTATACGGGGTTTTCTGAGTCGCCTTTTATCCATAATTATTTATTAAATATCAT
AGAGCTGGGCACGATTCTAATGTTGGTGCTGTTGGTGTCGGGCTTGCTGGTTTATCGCGGCGCCTATAGCTTGTTGCAGC
CGATTGAGCGTATCCATCACGTGGTGCAAGCAGTACAGTCGGGGCGCAATATTCGTATTGGCGCCTTAGGGTTAGATAGG
GATAACGAGTTATCGAACTTGGCCGAGCAGTTCGACAGTATGCTCGATCTGCTGCAGCGCCGAAATGCTCAGATCCAAGC
GGCGGCAGAGCAGCTTGAAATGAAGGTTGAAGAACGTACCCGCAGTTTGCAGGACAAAACCTTAGAGTTGCAACGTAACG
TGGCGTTACTGAATGAAACGCGTCAACAGCTCGTCACCAACGAAAAGCTCACCGCTCTGGGCGAGTTGACCGCTGGTATT
GCCCACGAAATCAATAATCCGACCGCCGTTATCCTCGGCAACATGGAGTTACTGCGCTACGAACTTGGCGATAATGCGGA
AGTGGTAAAAGAAGAAATTGATCTCGTTATTCAGCAGGTGGGACGGATCAGCACCATTATCCGTAGCCTGTTGCAGTACA
GTCGTCCGGGCGAATTTAACGCCCCGTTAGAAATGCATCCGATTACCCCCATTATTGAAGAAATGTTGGTGTTAGTGCGG
CATTCGATTCAGAAACAAGAAGTGGTATTGATCACTGAGTTAAACGCCAGTTGTCCAGTGCAGGTTAATCGACCGCAGTT
GCTGCAAGTCTTGATTAATCTGGTAGTAAACGCGGCGCATGCGATGGACGGTAAAGGACGTATCTGGGTGCGAACCTATG
ACTGGGTGCAGCAAGATATGCCGATTGGCGTCAAAATCGAAGTGGAAGATGAAGGTTCTGGAATAGCACCAGAGCAGCTA
GGGCGGATTTTCGACCCCTTTTACACCACGCGTAAGGATGGTACTGGTTTAGGGCTTTCGCTCAGTTACGGCATTATTAA
GCGGATTGGTGGCACGATAGAAGTGAGTTCAACCTTAGGTAAAGGTACGTTATTTACAATAGGCTTGTACCATGAGGCGA
AGGAAGATCAGCAAAACAATCCCTACGAGGGATTACACATTGCGGGCAACTACAGCGATATGTCTGCCGATTAG

Upstream 100 bases:

>100_bases
AATAAGTCTGCCGCAGCGAGGGATTTAGGCGTTTCGCGTAAAACTTTAGATCGTAAGTATAAAGAGTGGTTTGATTTCAG
CGGCGATCAGGAGTCATAGG

Downstream 100 bases:

>100_bases
CTTACCGATGAGTTTTGCCGAGTGAGATATGGCAGCTTGCCGTATTCGATTGATTACGTGTCATTAAAATATGGCTGCAG
TTGTTGGTTCTACTTTATGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MSFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLSVAENTLQQVQVRQEKQL
ERVVTSWTFQNDFRPLFSGKELTGEVIHRASLDAFLLEQKKQLNLDYLRLVTVAEAAADPDLRQILPKINGLLPYSGLMV
LPPERLSRIDPELAVTASIPIVATLRAQSPTKTVEERGLLSRSLLPVPDMQGKVAWYLDGGILFNRDIRIVDHIRDLVYD
KGTLPERSIGTVTIFLDNIRISTNVPLHFYPTGNETQGRALGSLVSEEVKEKVLTQGEQWVDRAFVFNDWFISAYAPLED
IRGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVYRGAYSLLQPIERIHHVVQAVQSGRNIRIGALGLDR
DNELSNLAEQFDSMLDLLQRRNAQIQAAAEQLEMKVEERTRSLQDKTLELQRNVALLNETRQQLVTNEKLTALGELTAGI
AHEINNPTAVILGNMELLRYELGDNAEVVKEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHPITPIIEEMLVLVR
HSIQKQEVVLITELNASCPVQVNRPQLLQVLINLVVNAAHAMDGKGRIWVRTYDWVQQDMPIGVKIEVEDEGSGIAPEQL
GRIFDPFYTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTLGKGTLFTIGLYHEAKEDQQNNPYEGLHIAGNYSDMSAD

Sequences:

>Translated_717_residues
MSFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLSVAENTLQQVQVRQEKQL
ERVVTSWTFQNDFRPLFSGKELTGEVIHRASLDAFLLEQKKQLNLDYLRLVTVAEAAADPDLRQILPKINGLLPYSGLMV
LPPERLSRIDPELAVTASIPIVATLRAQSPTKTVEERGLLSRSLLPVPDMQGKVAWYLDGGILFNRDIRIVDHIRDLVYD
KGTLPERSIGTVTIFLDNIRISTNVPLHFYPTGNETQGRALGSLVSEEVKEKVLTQGEQWVDRAFVFNDWFISAYAPLED
IRGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVYRGAYSLLQPIERIHHVVQAVQSGRNIRIGALGLDR
DNELSNLAEQFDSMLDLLQRRNAQIQAAAEQLEMKVEERTRSLQDKTLELQRNVALLNETRQQLVTNEKLTALGELTAGI
AHEINNPTAVILGNMELLRYELGDNAEVVKEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHPITPIIEEMLVLVR
HSIQKQEVVLITELNASCPVQVNRPQLLQVLINLVVNAAHAMDGKGRIWVRTYDWVQQDMPIGVKIEVEDEGSGIAPEQL
GRIFDPFYTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTLGKGTLFTIGLYHEAKEDQQNNPYEGLHIAGNYSDMSAD
>Mature_716_residues
SFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLSVAENTLQQVQVRQEKQLE
RVVTSWTFQNDFRPLFSGKELTGEVIHRASLDAFLLEQKKQLNLDYLRLVTVAEAAADPDLRQILPKINGLLPYSGLMVL
PPERLSRIDPELAVTASIPIVATLRAQSPTKTVEERGLLSRSLLPVPDMQGKVAWYLDGGILFNRDIRIVDHIRDLVYDK
GTLPERSIGTVTIFLDNIRISTNVPLHFYPTGNETQGRALGSLVSEEVKEKVLTQGEQWVDRAFVFNDWFISAYAPLEDI
RGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVYRGAYSLLQPIERIHHVVQAVQSGRNIRIGALGLDRD
NELSNLAEQFDSMLDLLQRRNAQIQAAAEQLEMKVEERTRSLQDKTLELQRNVALLNETRQQLVTNEKLTALGELTAGIA
HEINNPTAVILGNMELLRYELGDNAEVVKEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHPITPIIEEMLVLVRH
SIQKQEVVLITELNASCPVQVNRPQLLQVLINLVVNAAHAMDGKGRIWVRTYDWVQQDMPIGVKIEVEDEGSGIAPEQLG
RIFDPFYTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTLGKGTLFTIGLYHEAKEDQQNNPYEGLHIAGNYSDMSAD

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=36.5217391304348, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=36.283185840708, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081816, Length=269, Percent_Identity=29.7397769516729, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=31.4893617021277, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=28.125, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=272, Percent_Identity=26.8382352941176, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789808, Length=209, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789149, Length=456, Percent_Identity=21.4912280701754, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=28.0334728033473, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=27.3092369477912, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80783; Mature: 80652

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHH
DLSVAENTLQQVQVRQEKQLERVVTSWTFQNDFRPLFSGKELTGEVIHRASLDAFLLEQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
KQLNLDYLRLVTVAEAAADPDLRQILPKINGLLPYSGLMVLPPERLSRIDPELAVTASIP
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEECHHHHHHCCCCEEEEECCC
IVATLRAQSPTKTVEERGLLSRSLLPVPDMQGKVAWYLDGGILFNRDIRIVDHIRDLVYD
EEEEEECCCCHHHHHHHCCHHCCCCCCCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHC
KGTLPERSIGTVTIFLDNIRISTNVPLHFYPTGNETQGRALGSLVSEEVKEKVLTQGEQW
CCCCCCCCCCEEEEEEECEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHH
VDRAFVFNDWFISAYAPLEDIRGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVS
HHHHHEEECHHHEECCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLLVYRGAYSLLQPIERIHHVVQAVQSGRNIRIGALGLDRDNELSNLAEQFDSMLDLLQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
RNAQIQAAAEQLEMKVEERTRSLQDKTLELQRNVALLNETRQQLVTNEKLTALGELTAGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AHEINNPTAVILGNMELLRYELGDNAEVVKEEIDLVIQQVGRISTIIRSLLQYSRPGEFN
HHHCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
APLEMHPITPIIEEMLVLVRHSIQKQEVVLITELNASCPVQVNRPQLLQVLINLVVNAAH
CCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHH
AMDGKGRIWVRTYDWVQQDMPIGVKIEVEDEGSGIAPEQLGRIFDPFYTTRKDGTGLGLS
HCCCCCEEEEEEHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
LSYGIIKRIGGTIEVSSTLGKGTLFTIGLYHEAKEDQQNNPYEGLHIAGNYSDMSAD
HHHHHHHHCCCCEEEECCCCCCEEEEEEEEHHHHCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
SFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKA
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHH
DLSVAENTLQQVQVRQEKQLERVVTSWTFQNDFRPLFSGKELTGEVIHRASLDAFLLEQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
KQLNLDYLRLVTVAEAAADPDLRQILPKINGLLPYSGLMVLPPERLSRIDPELAVTASIP
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEECHHHHHHCCCCEEEEECCC
IVATLRAQSPTKTVEERGLLSRSLLPVPDMQGKVAWYLDGGILFNRDIRIVDHIRDLVYD
EEEEEECCCCHHHHHHHCCHHCCCCCCCCCCCCEEEEEECCEEEECCHHHHHHHHHHHHC
KGTLPERSIGTVTIFLDNIRISTNVPLHFYPTGNETQGRALGSLVSEEVKEKVLTQGEQW
CCCCCCCCCCEEEEEEECEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHH
VDRAFVFNDWFISAYAPLEDIRGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVS
HHHHHEEECHHHEECCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLLVYRGAYSLLQPIERIHHVVQAVQSGRNIRIGALGLDRDNELSNLAEQFDSMLDLLQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
RNAQIQAAAEQLEMKVEERTRSLQDKTLELQRNVALLNETRQQLVTNEKLTALGELTAGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AHEINNPTAVILGNMELLRYELGDNAEVVKEEIDLVIQQVGRISTIIRSLLQYSRPGEFN
HHHCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
APLEMHPITPIIEEMLVLVRHSIQKQEVVLITELNASCPVQVNRPQLLQVLINLVVNAAH
CCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHH
AMDGKGRIWVRTYDWVQQDMPIGVKIEVEDEGSGIAPEQLGRIFDPFYTTRKDGTGLGLS
HCCCCCEEEEEEHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
LSYGIIKRIGGTIEVSSTLGKGTLFTIGLYHEAKEDQQNNPYEGLHIAGNYSDMSAD
HHHHHHHHCCCCEEEECCCCCCEEEEEEEEHHHHCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]