Click here to switch to the map view.

The map label for this gene is atoC [H]

Identifier: 160877557

GI number: 160877557

Start: 5266218

End: 5267600

Strand: Reverse

Name: atoC [H]

Synonym: Sbal195_4456

Alternate gene names: 160877557

Gene position: 5267600-5266218 (Counterclockwise)

Preceding gene: 160877566

Following gene: 160877556

Centisome position: 98.51

GC content: 49.46

Gene sequence:

>1383_bases
ATGAGCCAGATAGATAATAACCTCAAGCCTCTTCCATCGGCAGTATCGGTACTGATTGTTGATGATGAACCCGGAATGCG
CAGTTTTTTAAATAAGGCACTCTCGAAGAAATTCGCCTTAGTCGAAACAGCGGGCAGTATCGAAGATGCGGAGCAGCTAC
GTAGCCGCTGCCATTTCGATTTGCTGATCGTCGACATTCGCCTCCCTGGCCGCTCGGGTATCGAATGGCATGAAGCGTTG
GATGAGCAGGGTCGTCGTTCGGACATCATTTTTATGACCGGCTATGCTGACATGGAAGTGGCGATTACCGCGCTGCGCGC
GGGTGCGTCTGACTTCATCATGAAACCTTTCCACCTTGAGCAGATGATGACAGCGGTCGATCGTTGTATCGAACGCCGCC
TGCTCAAACGCGAAAACTTGATGCTGCGCCGTGAGGTTTCAATCGGTTACTCATCGACCATTATTGGCAGCAGTGAGGCC
ATGAAGTCGGTGAAACATATTATCGAACGTGTGGCGCCGACCAATGCGGTTGTGCTGATCCAAGGTGAGTCGGGTACGGG
TAAGGAATTAGTTGCACGCCAATTGCATTTGCTCAGTGGACGTCAGGGACCTTTTGTCCCAGTCAACTGTGGCTCTATCG
CTCCTGAATTGCTCGAAAGTGAACTGTTTGGTCATACCGCAGGTGCATTTACGGGGGCGAAAGGCAATCGTGAAGGTTTA
TTCAGTTTTGCCTCGGGCGGGACGATTTTCCTCGATGAAATTGGCGAAATGCCACTGAAAATGCAAACGGCATTGCTCAG
AGTATTAGAGCAAAAAGCGATTCGCCCAGTGGGCAGCGAGAAAGAAGTGAACATTGATGTGCGAGTGATCGCGGCCACCA
ACCGCACTCTGATTGATGAAGTGGATGCGGGGAATTTCCGCCGTGATTTATATTATCGACTGAATGTGCTCGATATTTTA
ATCCCGCCATTACGTGACAGACCCGAAGATGTGGTCGAGTTAACCCATCATTTCACCCGTCAACTCGCTGCCGAATTAGG
GGTTAGAGAAGTCGTGTGGAGCCATGAGGACATGGTGAAGTTGCAACAACACGAGTGGCCGGGCAATATTCGTGAGCTGC
GCAATATGATTGAGCGCTGTATTTTACTGGGTAAACCACCGGCGGAATATTGGAAACAACAACTAAAGAGTGAGTCTTTA
TCGACATCGGGCTATCCATTGGATTGGCCGTTAAAAGAAGTCGAAAAACACCATGTGACTAGCGTTGTGGACTTACATTC
TGGCAATAAGTCTGCCGCAGCGAGGGATTTAGGCGTTTCGCGTAAAACTTTAGATCGTAAGTATAAAGAGTGGTTTGATT
TCAGCGGCGATCAGGAGTCATAG

Upstream 100 bases:

>100_bases
TGTCTCAGCACCTACTTCCTGTGGTTCATAGTGACCTATTCATCTATTTTCAGTGCTAGAATTGGTCGCAAATGAGTCAA
AATGTCCAGAAGCAGACAAT

Downstream 100 bases:

>100_bases
GGTGTCATTCTTCACTCACTTTTTTGGTGTCAGTTGGCAGCAAATGCAGGCCAAGGTGCGCTATCGCATATTAATCCTGA
CATTACTGCCTATTCTGCTG

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSQIDNNLKPLPSAVSVLIVDDEPGMRSFLNKALSKKFALVETAGSIEDAEQLRSRCHFDLLIVDIRLPGRSGIEWHEAL
DEQGRRSDIIFMTGYADMEVAITALRAGASDFIMKPFHLEQMMTAVDRCIERRLLKRENLMLRREVSIGYSSTIIGSSEA
MKSVKHIIERVAPTNAVVLIQGESGTGKELVARQLHLLSGRQGPFVPVNCGSIAPELLESELFGHTAGAFTGAKGNREGL
FSFASGGTIFLDEIGEMPLKMQTALLRVLEQKAIRPVGSEKEVNIDVRVIAATNRTLIDEVDAGNFRRDLYYRLNVLDIL
IPPLRDRPEDVVELTHHFTRQLAAELGVREVVWSHEDMVKLQQHEWPGNIRELRNMIERCILLGKPPAEYWKQQLKSESL
STSGYPLDWPLKEVEKHHVTSVVDLHSGNKSAAARDLGVSRKTLDRKYKEWFDFSGDQES

Sequences:

>Translated_460_residues
MSQIDNNLKPLPSAVSVLIVDDEPGMRSFLNKALSKKFALVETAGSIEDAEQLRSRCHFDLLIVDIRLPGRSGIEWHEAL
DEQGRRSDIIFMTGYADMEVAITALRAGASDFIMKPFHLEQMMTAVDRCIERRLLKRENLMLRREVSIGYSSTIIGSSEA
MKSVKHIIERVAPTNAVVLIQGESGTGKELVARQLHLLSGRQGPFVPVNCGSIAPELLESELFGHTAGAFTGAKGNREGL
FSFASGGTIFLDEIGEMPLKMQTALLRVLEQKAIRPVGSEKEVNIDVRVIAATNRTLIDEVDAGNFRRDLYYRLNVLDIL
IPPLRDRPEDVVELTHHFTRQLAAELGVREVVWSHEDMVKLQQHEWPGNIRELRNMIERCILLGKPPAEYWKQQLKSESL
STSGYPLDWPLKEVEKHHVTSVVDLHSGNKSAAARDLGVSRKTLDRKYKEWFDFSGDQES
>Mature_459_residues
SQIDNNLKPLPSAVSVLIVDDEPGMRSFLNKALSKKFALVETAGSIEDAEQLRSRCHFDLLIVDIRLPGRSGIEWHEALD
EQGRRSDIIFMTGYADMEVAITALRAGASDFIMKPFHLEQMMTAVDRCIERRLLKRENLMLRREVSIGYSSTIIGSSEAM
KSVKHIIERVAPTNAVVLIQGESGTGKELVARQLHLLSGRQGPFVPVNCGSIAPELLESELFGHTAGAFTGAKGNREGLF
SFASGGTIFLDEIGEMPLKMQTALLRVLEQKAIRPVGSEKEVNIDVRVIAATNRTLIDEVDAGNFRRDLYYRLNVLDILI
PPLRDRPEDVVELTHHFTRQLAAELGVREVVWSHEDMVKLQQHEWPGNIRELRNMIERCILLGKPPAEYWKQQLKSESLS
TSGYPLDWPLKEVEKHHVTSVVDLHSGNKSAAARDLGVSRKTLDRKYKEWFDFSGDQES

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=450, Percent_Identity=39.3333333333333, Blast_Score=314, Evalue=7e-87,
Organism=Escherichia coli, GI1790437, Length=439, Percent_Identity=39.4077448747153, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1790299, Length=465, Percent_Identity=38.2795698924731, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1788905, Length=446, Percent_Identity=35.4260089686099, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1786524, Length=321, Percent_Identity=44.2367601246106, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789233, Length=318, Percent_Identity=40.251572327044, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082117, Length=254, Percent_Identity=46.8503937007874, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1789087, Length=276, Percent_Identity=47.1014492753623, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI87082152, Length=235, Percent_Identity=47.6595744680851, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=37.987012987013, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI87081872, Length=261, Percent_Identity=39.463601532567, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1789828, Length=223, Percent_Identity=39.9103139013453, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=30.6122448979592, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=29.9145299145299, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51675; Mature: 51544

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIDNNLKPLPSAVSVLIVDDEPGMRSFLNKALSKKFALVETAGSIEDAEQLRSRCHFD
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
LLIVDIRLPGRSGIEWHEALDEQGRRSDIIFMTGYADMEVAITALRAGASDFIMKPFHLE
EEEEEEECCCCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCHHHH
QMMTAVDRCIERRLLKRENLMLRREVSIGYSSTIIGSSEAMKSVKHIIERVAPTNAVVLI
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEE
QGESGTGKELVARQLHLLSGRQGPFVPVNCGSIAPELLESELFGHTAGAFTGAKGNREGL
ECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
FSFASGGTIFLDEIGEMPLKMQTALLRVLEQKAIRPVGSEKEVNIDVRVIAATNRTLIDE
EEECCCCEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCHHHHC
VDAGNFRRDLYYRLNVLDILIPPLRDRPEDVVELTHHFTRQLAAELGVREVVWSHEDMVK
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHH
LQQHEWPGNIRELRNMIERCILLGKPPAEYWKQQLKSESLSTSGYPLDWPLKEVEKHHVT
HHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SVVDLHSGNKSAAARDLGVSRKTLDRKYKEWFDFSGDQES
HEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SQIDNNLKPLPSAVSVLIVDDEPGMRSFLNKALSKKFALVETAGSIEDAEQLRSRCHFD
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
LLIVDIRLPGRSGIEWHEALDEQGRRSDIIFMTGYADMEVAITALRAGASDFIMKPFHLE
EEEEEEECCCCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCHHHH
QMMTAVDRCIERRLLKRENLMLRREVSIGYSSTIIGSSEAMKSVKHIIERVAPTNAVVLI
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEE
QGESGTGKELVARQLHLLSGRQGPFVPVNCGSIAPELLESELFGHTAGAFTGAKGNREGL
ECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
FSFASGGTIFLDEIGEMPLKMQTALLRVLEQKAIRPVGSEKEVNIDVRVIAATNRTLIDE
EEECCCCEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCHHHHC
VDAGNFRRDLYYRLNVLDILIPPLRDRPEDVVELTHHFTRQLAAELGVREVVWSHEDMVK
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHH
LQQHEWPGNIRELRNMIERCILLGKPPAEYWKQQLKSESLSTSGYPLDWPLKEVEKHHVT
HHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SVVDLHSGNKSAAARDLGVSRKTLDRKYKEWFDFSGDQES
HEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]