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The map label for this gene is dinF [H]

Identifier: 160877424

GI number: 160877424

Start: 5103904

End: 5105271

Strand: Direct

Name: dinF [H]

Synonym: Sbal195_4322

Alternate gene names: 160877424

Gene position: 5103904-5105271 (Clockwise)

Preceding gene: 160877422

Following gene: 160877425

Centisome position: 95.45

GC content: 48.46

Gene sequence:

>1368_bases
ATGAATACTGCTAAATCAACTTGGCTCGACCTAATGCTTAACGGCGCGAAAAATCGTCAATTACTGGCGCTTGCCCTGCC
GATGATACTCTCCAATATCACTATCCCACTTTTGGGCTTAGTCGATACGGCTGTCATAGGTCATCTGAGTGAAGCCTATT
ATTTAGGGGGAGTCGCTGTCGGGTCAACGATTATCACATTAATCATTTGGTTATTGGGATTTTTGCGTATGGCGACCACA
GGTTTAGTCGCGCAGGCCTATGGTGCAAATGATCTTCACGCCCAGCATAAACTCTTAGTCCAAGGCGCTATGCTAGCTGT
GTTATTGGGCGCTGGCGTTATCGCGCTGCAAGTCCCGATATTAAATTTAGCGCTAGGATTATCCGAAGCGAGTAGCGAAG
TCGAGCGCTATTGCCGCGAGTATTTTCAGGTACGAATTTGGTCAACGCCCTTCGCCCTACTCAACCTCGTAATGCTTGGC
TGGCTATTGGGACGTCAGCAACCTAAAGCCGCCATGTGGCAGCTGATATTAGCCAACCTTGCCAATATTATTCTCGATGT
GGTGTTTGTCCTCGGCTTAGGCTGGGGCGTTAAGGGCGCCGCCCTCGCCTCAGTCTTTGCCGATATCACCGCTTTCTCAG
TCGCACTCACTATGGTGTTACAGCAACTCAAGCGCGAAGCCGATTTTCACTTATCCCAGCTATTACCCCATGTCACCCTG
ACAGGGTATGGCAAATTACTGAGGCTCAACACAGATATTTTTATCCGTAGCCTCTGCCTGCAAGCGGCCTTTGCCTTTAT
GACTTTTCATGGTGCTGGTCTGGGTGATAATACCGTTGCCGCCAATGCCGTGTTACTGAATTTACTGCTGTTAATCTCCT
ATGCACTCGATGGCATTGCCTATTATGCCGAGGCAGAAGTCGGCCGAGCCTATGGCCAAAAACAGGCGGAGCAATTACGG
GAAGCAGTGATCTTAGCCTGGAGCTGGTCGGCCATTACTGCGTTAGGGTTCTGCGCTGTATTCAGTCTTTTTGGCAGTAA
TATTATCGCGTTACTGACCAGCATTAATGAGGTCAGAGCCACAGCACAGACCTATCTTATCTGGCTGATATTTTTGCCTT
TATGGTCTTTTAGCTCGTATTTATTCGACGGGGTTTATATCGGTGCAGCTAAAGGCAAAGTGATGCGCAATAGCATGATA
CTCGCCACCTTCGGTGCATTTTTCCCGACATGGTATTTGCTGCAGCAACTGTTATTGCCTGAGCAAGGTAACCACGCCCT
TTGGGCCGCCATGAGTGTCTTTATGATCGCCAGAAGCCTAACGCTTGCGGGGCACTATTATTTCAGCAAAGACTTTTTGA
ATAAATAA

Upstream 100 bases:

>100_bases
GTGATATTGCAGAATGACCACGGCATGGGCAGAAAACGTCATTAGCCCTATGAGTGCCAACAGCACACGTTTAACCATAA
TGTGAACACCTCTGAAATTA

Downstream 100 bases:

>100_bases
ATCTGTAAAGACAGTAGTTTACAAATATCAAAATCACTATGATGTTGATTTTACAATTGTAACAAAGATGTGATTCTATA
ATGAAATGGATTTTACCGCT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNTAKSTWLDLMLNGAKNRQLLALALPMILSNITIPLLGLVDTAVIGHLSEAYYLGGVAVGSTIITLIIWLLGFLRMATT
GLVAQAYGANDLHAQHKLLVQGAMLAVLLGAGVIALQVPILNLALGLSEASSEVERYCREYFQVRIWSTPFALLNLVMLG
WLLGRQQPKAAMWQLILANLANIILDVVFVLGLGWGVKGAALASVFADITAFSVALTMVLQQLKREADFHLSQLLPHVTL
TGYGKLLRLNTDIFIRSLCLQAAFAFMTFHGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKQAEQLR
EAVILAWSWSAITALGFCAVFSLFGSNIIALLTSINEVRATAQTYLIWLIFLPLWSFSSYLFDGVYIGAAKGKVMRNSMI
LATFGAFFPTWYLLQQLLLPEQGNHALWAAMSVFMIARSLTLAGHYYFSKDFLNK

Sequences:

>Translated_455_residues
MNTAKSTWLDLMLNGAKNRQLLALALPMILSNITIPLLGLVDTAVIGHLSEAYYLGGVAVGSTIITLIIWLLGFLRMATT
GLVAQAYGANDLHAQHKLLVQGAMLAVLLGAGVIALQVPILNLALGLSEASSEVERYCREYFQVRIWSTPFALLNLVMLG
WLLGRQQPKAAMWQLILANLANIILDVVFVLGLGWGVKGAALASVFADITAFSVALTMVLQQLKREADFHLSQLLPHVTL
TGYGKLLRLNTDIFIRSLCLQAAFAFMTFHGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKQAEQLR
EAVILAWSWSAITALGFCAVFSLFGSNIIALLTSINEVRATAQTYLIWLIFLPLWSFSSYLFDGVYIGAAKGKVMRNSMI
LATFGAFFPTWYLLQQLLLPEQGNHALWAAMSVFMIARSLTLAGHYYFSKDFLNK
>Mature_455_residues
MNTAKSTWLDLMLNGAKNRQLLALALPMILSNITIPLLGLVDTAVIGHLSEAYYLGGVAVGSTIITLIIWLLGFLRMATT
GLVAQAYGANDLHAQHKLLVQGAMLAVLLGAGVIALQVPILNLALGLSEASSEVERYCREYFQVRIWSTPFALLNLVMLG
WLLGRQQPKAAMWQLILANLANIILDVVFVLGLGWGVKGAALASVFADITAFSVALTMVLQQLKREADFHLSQLLPHVTL
TGYGKLLRLNTDIFIRSLCLQAAFAFMTFHGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKQAEQLR
EAVILAWSWSAITALGFCAVFSLFGSNIIALLTSINEVRATAQTYLIWLIFLPLWSFSSYLFDGVYIGAAKGKVMRNSMI
LATFGAFFPTWYLLQQLLLPEQGNHALWAAMSVFMIARSLTLAGHYYFSKDFLNK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=428, Percent_Identity=46.4953271028037, Blast_Score=291, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49704; Mature: 49704

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAKSTWLDLMLNGAKNRQLLALALPMILSNITIPLLGLVDTAVIGHLSEAYYLGGVAV
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSTIITLIIWLLGFLRMATTGLVAQAYGANDLHAQHKLLVQGAMLAVLLGAGVIALQVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LNLALGLSEASSEVERYCREYFQVRIWSTPFALLNLVMLGWLLGRQQPKAAMWQLILANL
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ANIILDVVFVLGLGWGVKGAALASVFADITAFSVALTMVLQQLKREADFHLSQLLPHVTL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
TGYGKLLRLNTDIFIRSLCLQAAFAFMTFHGAGLGDNTVAANAVLLNLLLLISYALDGIA
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YYAEAEVGRAYGQKQAEQLREAVILAWSWSAITALGFCAVFSLFGSNIIALLTSINEVRA
HHHHHHHHHHHCHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQTYLIWLIFLPLWSFSSYLFDGVYIGAAKGKVMRNSMILATFGAFFPTWYLLQQLLLP
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQGNHALWAAMSVFMIARSLTLAGHYYFSKDFLNK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MNTAKSTWLDLMLNGAKNRQLLALALPMILSNITIPLLGLVDTAVIGHLSEAYYLGGVAV
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSTIITLIIWLLGFLRMATTGLVAQAYGANDLHAQHKLLVQGAMLAVLLGAGVIALQVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LNLALGLSEASSEVERYCREYFQVRIWSTPFALLNLVMLGWLLGRQQPKAAMWQLILANL
HHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ANIILDVVFVLGLGWGVKGAALASVFADITAFSVALTMVLQQLKREADFHLSQLLPHVTL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
TGYGKLLRLNTDIFIRSLCLQAAFAFMTFHGAGLGDNTVAANAVLLNLLLLISYALDGIA
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YYAEAEVGRAYGQKQAEQLREAVILAWSWSAITALGFCAVFSLFGSNIIALLTSINEVRA
HHHHHHHHHHHCHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQTYLIWLIFLPLWSFSSYLFDGVYIGAAKGKVMRNSMILATFGAFFPTWYLLQQLLLP
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQGNHALWAAMSVFMIARSLTLAGHYYFSKDFLNK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]