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The map label for this gene is hlyB [H]

Identifier: 160877335

GI number: 160877335

Start: 5009119

End: 5010696

Strand: Direct

Name: hlyB [H]

Synonym: Sbal195_4233

Alternate gene names: 160877335

Gene position: 5009119-5010696 (Clockwise)

Preceding gene: 160877332

Following gene: 160877336

Centisome position: 93.68

GC content: 48.42

Gene sequence:

>1578_bases
ATGGGATTAGACCAGAACACTCTGACGGCTTTGCCCTCGGTGATCGCGAGTATTCTACTCATCATCATAGGTATCTCATC
CTATCGTAGCTTTACCGATCTCGGTGAAACTAGCCGTCGCTTAGTCAACAATACCCAACTGGCAGAAACCTTTACCAATA
TACGTGCTGAATTCTTTGAAATTCGTTTAGCGACGCTAGTCCATAATGAGAAAGGCATTACCGAACATCAACAGAACATT
GGCCAGCTAGTCGCTAAACTCTCTGAATTTAATACCAATTTCATGGGCCAAAATGCGCGTAACATTCAGACTTTACAGCC
ACAGATAGAGCAATATGTCCGCCTCTACCGACAAGAAGTCGCCCTTGCTGAGCGCACCGCCACAGAAGCGGAATTAACTC
AGGAACGTCGTGAACTCGGTCCTAAAGTCAGCGATCAAATTAATCAACTCGTTTCACTAATCACTATCCGTAACCATGAG
TTAGGAACTCAGGCAGGAAGTAAGATTGCTATCGCAGAAAGCTTGTTACTGGGCCTGATCTTATTTGCCATCATCGCCTC
TCTCCTCAGCGCGCTCTTTATGAGCAAACGCTTAGTTCGGATAGTCAATGACATTAAGCTGGTAATGGAACGCCTAGCCA
ATGGCGACCTGACACATAAGACAAACATAAAGGGTGACAACGAACTCTGCTCACTCGCCACCGATCTCGATCGCGTTATC
GATAATCTACGCCATATCATCTCAGATATTACCCAAGCCTCAGATCACATGTCTGACCAAATTGGCCAACTGAATGTGCA
ATCCAATACTAATAGTGGTGCGCTACAAACTCACGCAGTCGAAACCGACCAAGTCGTAACGGCCATGACAGAAATGAGCG
CGACTGCCCATAACGTTGCAGGTGATGCCGCGTCTGCAGCCCAGTTTACTCAGCAAGCCAATGAACAAGCTGATAAATCG
AAGAAAGCCGTTGAACAGGCCGCCAACACTGTGATTGCCTTGGTGACTAAAGTCGATGTAGCAGCCGATGCGATTAATGA
TATGAACGAAAACACTCGTCATATCGCCGCTATTTTAAATGTAATAGGCGAGATTGCCGATCAGACCAATCTGCTCGCGC
TTAATGCGGCCATCGAAGCCGCCCGTGCAGGTGAACAAGGTCGAGGCTTTGCCGTTGTCGCCGATGAAGTGCGTACATTG
GCCGCTCGTACTCAAGCCAGTACATCCGAGATTAATCAGATGCTTGAACGTTTACGCCGCGGTGCCGATGCAGCCGTGAC
CGCAATGGAGCACACCAAACACAGTTGCCAACAAGCCGCCGACACAACCACTCTGGTAACGGAAAACCTCGATACCCTGA
CCGCTTATGTGTTCGATATTAATGGGCTCAGCACTCAAATCGCCACCGCCGCCGAAGAGCAAAGCGCCGTGACCGAAGAA
ATAAACCGTAATCTGACCACCATTCGTGAAATGGTCGATGAACTGAATCAAAGCGGTAAAGCCACACTTAACAGCGCTAC
AGCTTTAGCCGCGACGAAGGAACAACTCGTCGGCGTGGTATCGCATTTTAAGCTTTAG

Upstream 100 bases:

>100_bases
CTTCATCTTTAAATGCCTGCGGATAACTCTTATGTGATTTTTTCAGACTCATATAGACCTCTTAATTTATTGACCATACT
GTCTCAAAATTAAGTGTCCG

Downstream 100 bases:

>100_bases
GTTTAGGTTCACTGAAAAAAGCTTTTAAATCTGCGGCCTAAAAACAAAAATTATTAGGCCGCAGATTTTTAGATCAGATA
TAAAGCGAGTCACGCACCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MGLDQNTLTALPSVIASILLIIIGISSYRSFTDLGETSRRLVNNTQLAETFTNIRAEFFEIRLATLVHNEKGITEHQQNI
GQLVAKLSEFNTNFMGQNARNIQTLQPQIEQYVRLYRQEVALAERTATEAELTQERRELGPKVSDQINQLVSLITIRNHE
LGTQAGSKIAIAESLLLGLILFAIIASLLSALFMSKRLVRIVNDIKLVMERLANGDLTHKTNIKGDNELCSLATDLDRVI
DNLRHIISDITQASDHMSDQIGQLNVQSNTNSGALQTHAVETDQVVTAMTEMSATAHNVAGDAASAAQFTQQANEQADKS
KKAVEQAANTVIALVTKVDVAADAINDMNENTRHIAAILNVIGEIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTL
AARTQASTSEINQMLERLRRGADAAVTAMEHTKHSCQQAADTTTLVTENLDTLTAYVFDINGLSTQIATAAEEQSAVTEE
INRNLTTIREMVDELNQSGKATLNSATALAATKEQLVGVVSHFKL

Sequences:

>Translated_525_residues
MGLDQNTLTALPSVIASILLIIIGISSYRSFTDLGETSRRLVNNTQLAETFTNIRAEFFEIRLATLVHNEKGITEHQQNI
GQLVAKLSEFNTNFMGQNARNIQTLQPQIEQYVRLYRQEVALAERTATEAELTQERRELGPKVSDQINQLVSLITIRNHE
LGTQAGSKIAIAESLLLGLILFAIIASLLSALFMSKRLVRIVNDIKLVMERLANGDLTHKTNIKGDNELCSLATDLDRVI
DNLRHIISDITQASDHMSDQIGQLNVQSNTNSGALQTHAVETDQVVTAMTEMSATAHNVAGDAASAAQFTQQANEQADKS
KKAVEQAANTVIALVTKVDVAADAINDMNENTRHIAAILNVIGEIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTL
AARTQASTSEINQMLERLRRGADAAVTAMEHTKHSCQQAADTTTLVTENLDTLTAYVFDINGLSTQIATAAEEQSAVTEE
INRNLTTIREMVDELNQSGKATLNSATALAATKEQLVGVVSHFKL
>Mature_524_residues
GLDQNTLTALPSVIASILLIIIGISSYRSFTDLGETSRRLVNNTQLAETFTNIRAEFFEIRLATLVHNEKGITEHQQNIG
QLVAKLSEFNTNFMGQNARNIQTLQPQIEQYVRLYRQEVALAERTATEAELTQERRELGPKVSDQINQLVSLITIRNHEL
GTQAGSKIAIAESLLLGLILFAIIASLLSALFMSKRLVRIVNDIKLVMERLANGDLTHKTNIKGDNELCSLATDLDRVID
NLRHIISDITQASDHMSDQIGQLNVQSNTNSGALQTHAVETDQVVTAMTEMSATAHNVAGDAASAAQFTQQANEQADKSK
KAVEQAANTVIALVTKVDVAADAINDMNENTRHIAAILNVIGEIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLA
ARTQASTSEINQMLERLRRGADAAVTAMEHTKHSCQQAADTTTLVTENLDTLTAYVFDINGLSTQIATAAEEQSAVTEEI
NRNLTTIREMVDELNQSGKATLNSATALAATKEQLVGVVSHFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=433, Percent_Identity=24.2494226327945, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=30.4918032786885, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=27.8089887640449, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788195, Length=278, Percent_Identity=30.2158273381295, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789453, Length=324, Percent_Identity=28.0864197530864, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57001; Mature: 56870

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLDQNTLTALPSVIASILLIIIGISSYRSFTDLGETSRRLVNNTQLAETFTNIRAEFFE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLATLVHNEKGITEHQQNIGQLVAKLSEFNTNFMGQNARNIQTLQPQIEQYVRLYRQEV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALAERTATEAELTQERRELGPKVSDQINQLVSLITIRNHELGTQAGSKIAIAESLLLGLI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LFAIIASLLSALFMSKRLVRIVNDIKLVMERLANGDLTHKTNIKGDNELCSLATDLDRVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DNLRHIISDITQASDHMSDQIGQLNVQSNTNSGALQTHAVETDQVVTAMTEMSATAHNVA
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
GDAASAAQFTQQANEQADKSKKAVEQAANTVIALVTKVDVAADAINDMNENTRHIAAILN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VIGEIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAARTQASTSEINQMLERLRR
HHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHC
GADAAVTAMEHTKHSCQQAADTTTLVTENLDTLTAYVFDINGLSTQIATAAEEQSAVTEE
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
INRNLTTIREMVDELNQSGKATLNSATALAATKEQLVGVVSHFKL
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLDQNTLTALPSVIASILLIIIGISSYRSFTDLGETSRRLVNNTQLAETFTNIRAEFFE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLATLVHNEKGITEHQQNIGQLVAKLSEFNTNFMGQNARNIQTLQPQIEQYVRLYRQEV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALAERTATEAELTQERRELGPKVSDQINQLVSLITIRNHELGTQAGSKIAIAESLLLGLI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LFAIIASLLSALFMSKRLVRIVNDIKLVMERLANGDLTHKTNIKGDNELCSLATDLDRVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DNLRHIISDITQASDHMSDQIGQLNVQSNTNSGALQTHAVETDQVVTAMTEMSATAHNVA
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
GDAASAAQFTQQANEQADKSKKAVEQAANTVIALVTKVDVAADAINDMNENTRHIAAILN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VIGEIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAARTQASTSEINQMLERLRR
HHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHC
GADAAVTAMEHTKHSCQQAADTTTLVTENLDTLTAYVFDINGLSTQIATAAEEQSAVTEE
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
INRNLTTIREMVDELNQSGKATLNSATALAATKEQLVGVVSHFKL
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]