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The map label for this gene is gltT [H]

Identifier: 160875724

GI number: 160875724

Start: 3097331

End: 3098653

Strand: Direct

Name: gltT [H]

Synonym: Sbal195_2612

Alternate gene names: 160875724

Gene position: 3097331-3098653 (Clockwise)

Preceding gene: 160875722

Following gene: 160875725

Centisome position: 57.92

GC content: 44.07

Gene sequence:

>1323_bases
ATGGCAATTTCGATAAAAAATAAACTCGGCCTTACAAGTAAAATTCTGATCGGTATGGGAACAGGTATTGCCTTAGGTCT
CTTACTCCGCAATGCCTTTCCAGAAAGCGATATCGTAAAAGACTATATTACCGAAGGTTTCTTACATGTTATCGGCACCA
TTTTCATCTCCAGCTTAAAAATGTTAGTGGTTCCTTTAGTCTTTATTTCATTAGTTTGTGGAACTTGCTCACTGAGTGAG
CCTTCAAAATTGGGCCGTTTAGGGGGCAAAACCCTCGCCTTCTATTTATTCACCACCGCTATTGCTCTCGTGGTTGCGAT
TGTCAGTGCAGTCCTTATTCATCCTGGGAACGCTTCACTGGCTACAGAGAAAATGGAGTACATCGCCAAAGAAGCGCCAA
GTCTTTCAAGTGTCCTAATCAATATAGTGCCCACTAATCCGATGCAGGCATTGAGTGAGGGCAATATGCTGCAAATCATT
ATTTTTGCGGTGATTTTTGGCTTTGCCATTGCCCATATAGGTGAGCGTGGTAAACGCGTGGCGGCTTTGTTTGAAGATTT
AAATGAAGTCATCATGCGTGTCGTAACACTGATCATGCAGCTTGCACCTTATGGGGTGTTTGCGCTGATGGCAAAACTTG
CATTAACGCTCGGTTTAGGAACCTTTGAGAGTGTCGTCAAATATTTCTTCGTGGTTCTCGGTGTATTACTGGTCCATGCG
TTTATTGTTTACCCTACACTTCTAAAACTTTTCTCTGGCCTCAATCCGTTAATATTTATCCGTAAAATGCGCGATGTGCA
GCTGTTTGCCTTTTCAACAGCAAGTTCAAATGCCACTTTACCGATTACCATAGAAGCCTCTGAACATAGATTAGGTGTCG
ATAATAAGATTGCCGCCTTTACACTCCCCTTAGGTGCAACCATTAACATGGATGGCACCGCAATCATGCAAGGTGTGGCA
ACTGTATTTATCGCTCAGGTTTTTGGCATTGAACTCTCGCTCACCGATTATGCCGCCGTCGTAGTGACAGCGACATTGGC
ATCAATTGGTACCGCAGGCGTACCGGGTGTCGGACTTATCATGCTGGCCATGGTACTGAATCAAGTTGGTTTACCAGTTG
AAGGTATTGCACTGATTATCGGTGTTGATCGCCTACTCGACATGGTACGTACTGCAGTAAACGTCACCGGTGATTGTGTG
GCGACCGTGGTCATTGCGAAATCTGAAGGTGAATTTAACGAGCAAGTGTTTAACGACACTCAAGCGGGTAAGGTTGCTAG
AAATTTTGATGAGCAAGTTCATCATTCAAATAGCTCTAACTAG

Upstream 100 bases:

>100_bases
TAAATACTTTAACGCTATTTGTCATTTCATCTTCGCCGTTTTCTTGCTAGTCTTGTGAGCGCCAAAAAATAGAATGTATA
AAAAACACACAGGACTCCCC

Downstream 100 bases:

>100_bases
CCTTAGTTAAATACCCATCACGCCCAGCCTCTGTGTTGGGCGTTTTTGTTTGCGCTTTTTGTTTATACTTTTATCTGTAC
TTAGCCCAATTAATTTTTCT

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSE
PSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASLATEKMEYIAKEAPSLSSVLINIVPTNPMQALSEGNMLQII
IFAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLGVLLVHA
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAFTLPLGATINMDGTAIMQGVA
TVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCV
ATVVIAKSEGEFNEQVFNDTQAGKVARNFDEQVHHSNSSN

Sequences:

>Translated_440_residues
MAISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSE
PSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASLATEKMEYIAKEAPSLSSVLINIVPTNPMQALSEGNMLQII
IFAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLGVLLVHA
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAFTLPLGATINMDGTAIMQGVA
TVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCV
ATVVIAKSEGEFNEQVFNDTQAGKVARNFDEQVHHSNSSN
>Mature_439_residues
AISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSEP
SKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASLATEKMEYIAKEAPSLSSVLINIVPTNPMQALSEGNMLQIII
FAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLGVLLVHAF
IVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAFTLPLGATINMDGTAIMQGVAT
VFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVA
TVVIAKSEGEFNEQVFNDTQAGKVARNFDEQVHHSNSSN

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=409, Percent_Identity=35.4523227383863, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI40254478, Length=511, Percent_Identity=30.7240704500978, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI66773030, Length=405, Percent_Identity=33.3333333333333, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4827012, Length=332, Percent_Identity=37.6506024096386, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI194239697, Length=430, Percent_Identity=32.3255813953488, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI21314632, Length=444, Percent_Identity=31.5315315315315, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI5032093, Length=371, Percent_Identity=36.9272237196765, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI223468566, Length=252, Percent_Identity=38.8888888888889, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI223468564, Length=246, Percent_Identity=39.4308943089431, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI262359914, Length=342, Percent_Identity=33.0409356725146, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI301601644, Length=170, Percent_Identity=40.5882352941176, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790514, Length=443, Percent_Identity=34.7629796839729, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1789947, Length=432, Percent_Identity=30.787037037037, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1788024, Length=420, Percent_Identity=32.3809523809524, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789473, Length=274, Percent_Identity=31.021897810219, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71983099, Length=434, Percent_Identity=33.6405529953917, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI71983106, Length=434, Percent_Identity=33.6405529953917, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17537407, Length=487, Percent_Identity=34.4969199178645, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI193206505, Length=395, Percent_Identity=36.2025316455696, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI71996953, Length=446, Percent_Identity=32.9596412556054, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI193206654, Length=432, Percent_Identity=32.4074074074074, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17541374, Length=392, Percent_Identity=32.3979591836735, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24583025, Length=435, Percent_Identity=32.4137931034483, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17137668, Length=435, Percent_Identity=32.4137931034483, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24583023, Length=435, Percent_Identity=32.4137931034483, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281360481, Length=452, Percent_Identity=30.9734513274336, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281360483, Length=452, Percent_Identity=30.9734513274336, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI17137666, Length=452, Percent_Identity=30.9734513274336, Blast_Score=149, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 46774; Mature: 46643

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLK
CEEEECCCCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ATEKMEYIAKEAPSLSSVLINIVPTNPMQALSEGNMLQIIIFAVIFGFAIAHIGERGKRV
HHHHHHHHHHCCCCHHHHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLGVLLVHA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAF
HHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEE
TLPLGATINMDGTAIMQGVATVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLI
EECCCCEECCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHH
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNEQVFNDT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCC
QAGKVARNFDEQVHHSNSSN
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLK
EEEECCCCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ATEKMEYIAKEAPSLSSVLINIVPTNPMQALSEGNMLQIIIFAVIFGFAIAHIGERGKRV
HHHHHHHHHHCCCCHHHHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLGVLLVHA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAF
HHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEE
TLPLGATINMDGTAIMQGVATVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLI
EECCCCEECCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHH
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNEQVFNDT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCC
QAGKVARNFDEQVHHSNSSN
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]