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The map label for this gene is pyrH [H]

Identifier: 160874600

GI number: 160874600

Start: 1785367

End: 1786104

Strand: Direct

Name: pyrH [H]

Synonym: Sbal195_1483

Alternate gene names: 160874600

Gene position: 1785367-1786104 (Clockwise)

Preceding gene: 160874599

Following gene: 160874601

Centisome position: 33.39

GC content: 48.24

Gene sequence:

>738_bases
ATGAGCACCAATCCAAAACCCGCATTTAGACGCATTCTTCTTAAATTAAGTGGCGAAGCACTGATGGGCGACGAAGGCTT
CGGCATCGATCCCAAAGTATTAGATCGCATGGCTCAGGAAGTGAAAGAGCTGGTTGAGCTGGGTATTCAGGTGGGTGTGG
TTATTGGTGGTGGTAATCTGTTTCGCGGTGAAGGCCTAGCAAAAGCAGGCATGAACCGTGTGGTGGGCGATCACATGGGT
ATGCTGGCAACGGTTATGAACGGCTTGGCAATGCGCGACGCCTTGCACCGTGCCTATGTTAATGCCCGTCTGATGTCAGC
TATCCCGTTAAAGGGTGTGTGTGACGATTACAATTGGGCTGAAGCGATCAGCTTGCTAAAATCTGGCCGAGTGGTTATTT
TTGCTGCCGGTACAGGTAATCCATTCTGCACGACCGATTCTGCGGCCTGTTTACGCGGCATTGAAATCGAAGCTGAAGTT
GTGTTGAAAGGCACTAAAGTCGACGGTGTATACTCCGAAGACCCAATGAAGAACCCAGACGCCGTTAAGTATGATGAAGT
GACTTATGCGGAAATTCTGGAAAAAGAATTAAAAGTAATGGACTTAGCAGCCTTTACTATGGCGCGTGATCACGACATGC
CTATTTTAGTCTTCAACATGAACAAGCCTGGCGCTCTTCGCCGCGTTATCATGGGTGAAGAAGAAGGCACGCTGATCAGA
GCGAAAAAAGTTATTTAA

Upstream 100 bases:

>100_bases
CTGCTCAAATCGCTGCTTCTAAAAAGGCTTAATCGCCAACGCTAAATACCCCCAAGACCGCGGCAATAGCTGCGGTCTTG
TTATGACCAGGATAAAAATT

Downstream 100 bases:

>100_bases
TGACCAAGAAGGACATTTAACGTGATTGAGAACATTAAGAAAGATGCGCAAGAACGCATGGGTAAATGTGTAGACGCAAC
TAAAAACCAAATGGCAAAAG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEV
VLKGTKVDGVYSEDPMKNPDAVKYDEVTYAEILEKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVIMGEEEGTLIR
AKKVI

Sequences:

>Translated_245_residues
MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEV
VLKGTKVDGVYSEDPMKNPDAVKYDEVTYAEILEKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVIMGEEEGTLIR
AKKVI
>Mature_244_residues
STNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMGM
LATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVV
LKGTKVDGVYSEDPMKNPDAVKYDEVTYAEILEKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVIMGEEEGTLIRA
KKVI

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=239, Percent_Identity=82.4267782426778, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26602; Mature: 26470

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNL
CCCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSEDPMKNPD
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEECCEECCEECCCCCCCCC
AVKYDEVTYAEILEKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVIMGEEEGTLIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEE
AKKVI
EECCC
>Mature Secondary Structure 
STNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNL
CCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSEDPMKNPD
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEECCEECCEECCCCCCCCC
AVKYDEVTYAEILEKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVIMGEEEGTLIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEE
AKKVI
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA