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The map label for this gene is frr [H]

Identifier: 160874601

GI number: 160874601

Start: 1786126

End: 1786683

Strand: Direct

Name: frr [H]

Synonym: Sbal195_1484

Alternate gene names: 160874601

Gene position: 1786126-1786683 (Clockwise)

Preceding gene: 160874600

Following gene: 160874602

Centisome position: 33.4

GC content: 44.8

Gene sequence:

>558_bases
GTGATTGAGAACATTAAGAAAGATGCGCAAGAACGCATGGGTAAATGTGTAGACGCAACTAAAAACCAAATGGCAAAAGT
ACGTACAGGTCGTGCCCACCCAAGCCTGCTTGATTCAATTCAAGTGTCTTACTACGGTACTATGACACCACTGAACCAAG
TGGCAAATGTCGGTGTTGAAGATTCACGCACTCTGTCTGTGACTGTATTCGATCGTAGTGCTATCCAAGCCGTTGAAAAG
GCCATTATGAGCTCAGATTTAGGTCTGAACCCTATGTCTGCTGGCGCGACCTTGCGTATTCCATTACCTGCGCTGACGGA
AGAGCGTCGTAAAGACTTCATCAAAGTTGTGCGTAACGAAGCTGAAAACGGTCGTATCGCTATCCGTAACGTACGTCGTG
ATGCCATTTCTGAAGTGAAAAAACTTGAGAAAGCCAAAGCTTGTACTGAAGATGATGTTCGTCGCAGCGAAGAAGAGGTA
CAAAAGTTCACCGATGCTCACATTAAAAAGGTCGATGAGATTTTAGCGGCCAAAGAAATTGAGTTGATGGAAGTCTAA

Upstream 100 bases:

>100_bases
GAACAAGCCTGGCGCTCTTCGCCGCGTTATCATGGGTGAAGAAGAAGGCACGCTGATCAGAGCGAAAAAAGTTATTTAAT
GACCAAGAAGGACATTTAAC

Downstream 100 bases:

>100_bases
TCTCAAGTTCGATAAGCTAGAGTTGATGCGCCGTGTAGGGGTATACTACACGGCGTTTGTCTATTTTAAAGGGCTGTATT
AGATGTCATCCACAGTGGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEV
QKFTDAHIKKVDEILAAKEIELMEV

Sequences:

>Translated_185_residues
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEV
QKFTDAHIKKVDEILAAKEIELMEV
>Mature_185_residues
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEV
QKFTDAHIKKVDEILAAKEIELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=27.5167785234899, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=65.2173913043478, Blast_Score=241, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=29.4797687861272, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20684; Mature: 20684

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DSRTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNE
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCC
AENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEVQKFTDAHIKKVDEILAAKEI
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DSRTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNE
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCC
AENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEVQKFTDAHIKKVDEILAAKEI
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA