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The map label for this gene is hlyB [H]

Identifier: 160874196

GI number: 160874196

Start: 1273220

End: 1275241

Strand: Reverse

Name: hlyB [H]

Synonym: Sbal195_1076

Alternate gene names: 160874196

Gene position: 1275241-1273220 (Counterclockwise)

Preceding gene: 160874197

Following gene: 160874188

Centisome position: 23.85

GC content: 46.83

Gene sequence:

>2022_bases
ATGAAATTTAACGTAGCCACCAGAGTGATTGGCGGTTTTGGTATTGTCACACTTTTGCTCGTGGTGCTAGGATTTACATC
CTACTTAACCAACAACAGCCTAAAAGCAAGCTCGGCGATGATGCAAGAATTAAGCTTGCCCGCGCTTAAGTCGACCAATC
ACCTCAGTGAAACCTTGAGCGAGCAACAAAGACAAATCCTGATTGCCTATCACACACCTAAATCGGCCAATATTCCCAGT
ATTCGCAAAGTGTTCGATGATCATGGAACTCAGTTCAAAAACGAAATAGCTAACATCACCCAATTAGTGAAAAGCCAGCC
AGAGCTTACCTCCTTAATCAGCCAATTAAGCGGTAGCTTCTCAAGCTTTGAACGAGACAGCCTTGCTATGATCGCCGAAC
GTGAAGCTTCATTAAGCAAGCAAGAACAGTTAGTTAATCTAAAGAAAAAACTCGAAAATGCCGCCGATGATGCCTCATCG
GAACTGCTCGATATTGTTGATTTAGAAAGCAGTCAAAATCCCGATGAGCAGAGTCTGGCCGCGTCAGCCAGCGCGATTGA
TACTAGCCTCGGGAATATCATCACCACTATCGCAGACTTAGTCACCAATGAAGAAGACAGTAAGCACGAACTAATCTCTA
AAGAACTTGACTACATTATCAGCGAAACCAAGAACAAACTTGAATATGTGAATCGTCACGGTCAAGGTATCGTCGAAGCG
AATACCTTAAGTTCAGTCACTAAAGATATTGAAAAAGTTTTAGCGCTAGTTACCGGCCCGCAATCTATGTTACAGCTGAA
GTCGAGCCAGCTTTCCCATGCTAAAGAAGCCGTGGTCAAACTCGGTATTATCGAAAAAGACGTGAAAGTCATTAACACGA
ACATGGATGATGTGAGTAATAACATCGAACTTGTTGCCGCCAACATGAGTAACGACACCATAGCTAAGATTGACTCTGCT
AGCATACAAACAATGATTGTGGTGTTAGTTGCCATTATTGTCGCTGTTATTGTGAGTTTTGCTGTAGTGAACCCGCTCAA
ACGCTCACTCAGCCAAGTGAACAATGCCCTTAACGTCTTAGCCTCAGGCAACCTTACCCATAAGCTTGATGACTCTGGAC
ACGATGAATTTGCAGAGCTGGCGAAAAACTGCAACCGTCTCGTCGATAGCTTACGCAGTTTGATTATCGGTATCTTGGAT
AGATCGAACCAACTGGCCGCGGCAGCTGAACAAACGTCGGCAATCACAGCGCAAACCACTTCGGGCATTCAAGAGCAAAA
AAGCCAAGTGGACCAAGTGGCCACTGCAACCACAGAACTGAGCTCTAGCGCGCAGCAGGTGTCCTTAAGTGCTGATCAAG
CCCTTGAGCAAATCAAGCAAGCCGACCAAGAAACTCAGCATATGCGAGCCATTGCCGAAGAGAACAAACTGACGATTTTG
GCTTTAGCCGATGAAGTGGCCAAGGCAGGCGTTGTGATCAATAAAGTGCAGTCTGATAGCGCCTCAATTGGCTCAATTTT
GGATGTGATCCGCGGCATTGCAGAGCAGACTAACCTACTCGCCCTTAACGCCGCCATTGAAGCTGCTAGAGCCGGTGAAC
AAGGTCGTGGCTTTGCGGTGGTTGCCGATGAAGTCCGTAGCTTAGCCTCACGCACTCAGGTATCGACCCGAGAGATCCAA
CAGATGATCGAAGTGTTGCAACAAGGTGCAGAGCAAGCCGTTGCCGCCATGGATATGGGACGTGCTCAGGCAAATGCCTG
TGTTGAAAAAACTGAGCAAGCCAACATTGCCCTCGAAACCATTAGCCAGTCTGTGCATAAGGCCTATGACTCAGGCACTC
ATATCGCCCATGCAGCTCAAGAGCAGAATTTAGTGAGTCAGCAAGTGTCTGAGAAACTCGAGCATATTGCTGCCATTTCG
GAAGAAACGGCCATCGGTGCAGATCAAACGGCTCAGTCTAGCCATCAAGTCGCCAAACTAGCCGAAGAACTTCAAGCCTC
AGTTGGTGAATTTAGAGTCTAA

Upstream 100 bases:

>100_bases
TTAAACTAAAACAGCTTAAAGTCGATAACAGACTGAGCCGCCTAACCCTGAAATCGCCCTGTTTTCATTTGGAAAAATAT
AATAAAAATCGGAGTATCCT

Downstream 100 bases:

>100_bases
ATGTTAATTGTTAAAATCCACTAAACCAAGGGTCGCATAGCGGCCCTTTATTTTGGGCCAAATTTACTTTCCCTATCATA
CCAATCACTCGCTCTGACCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MKFNVATRVIGGFGIVTLLLVVLGFTSYLTNNSLKASSAMMQELSLPALKSTNHLSETLSEQQRQILIAYHTPKSANIPS
IRKVFDDHGTQFKNEIANITQLVKSQPELTSLISQLSGSFSSFERDSLAMIAEREASLSKQEQLVNLKKKLENAADDASS
ELLDIVDLESSQNPDEQSLAASASAIDTSLGNIITTIADLVTNEEDSKHELISKELDYIISETKNKLEYVNRHGQGIVEA
NTLSSVTKDIEKVLALVTGPQSMLQLKSSQLSHAKEAVVKLGIIEKDVKVINTNMDDVSNNIELVAANMSNDTIAKIDSA
SIQTMIVVLVAIIVAVIVSFAVVNPLKRSLSQVNNALNVLASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRSLIIGILD
RSNQLAAAAEQTSAITAQTTSGIQEQKSQVDQVATATTELSSSAQQVSLSADQALEQIKQADQETQHMRAIAEENKLTIL
ALADEVAKAGVVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQVSTREIQ
QMIEVLQQGAEQAVAAMDMGRAQANACVEKTEQANIALETISQSVHKAYDSGTHIAHAAQEQNLVSQQVSEKLEHIAAIS
EETAIGADQTAQSSHQVAKLAEELQASVGEFRV

Sequences:

>Translated_673_residues
MKFNVATRVIGGFGIVTLLLVVLGFTSYLTNNSLKASSAMMQELSLPALKSTNHLSETLSEQQRQILIAYHTPKSANIPS
IRKVFDDHGTQFKNEIANITQLVKSQPELTSLISQLSGSFSSFERDSLAMIAEREASLSKQEQLVNLKKKLENAADDASS
ELLDIVDLESSQNPDEQSLAASASAIDTSLGNIITTIADLVTNEEDSKHELISKELDYIISETKNKLEYVNRHGQGIVEA
NTLSSVTKDIEKVLALVTGPQSMLQLKSSQLSHAKEAVVKLGIIEKDVKVINTNMDDVSNNIELVAANMSNDTIAKIDSA
SIQTMIVVLVAIIVAVIVSFAVVNPLKRSLSQVNNALNVLASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRSLIIGILD
RSNQLAAAAEQTSAITAQTTSGIQEQKSQVDQVATATTELSSSAQQVSLSADQALEQIKQADQETQHMRAIAEENKLTIL
ALADEVAKAGVVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQVSTREIQ
QMIEVLQQGAEQAVAAMDMGRAQANACVEKTEQANIALETISQSVHKAYDSGTHIAHAAQEQNLVSQQVSEKLEHIAAIS
EETAIGADQTAQSSHQVAKLAEELQASVGEFRV
>Mature_673_residues
MKFNVATRVIGGFGIVTLLLVVLGFTSYLTNNSLKASSAMMQELSLPALKSTNHLSETLSEQQRQILIAYHTPKSANIPS
IRKVFDDHGTQFKNEIANITQLVKSQPELTSLISQLSGSFSSFERDSLAMIAEREASLSKQEQLVNLKKKLENAADDASS
ELLDIVDLESSQNPDEQSLAASASAIDTSLGNIITTIADLVTNEEDSKHELISKELDYIISETKNKLEYVNRHGQGIVEA
NTLSSVTKDIEKVLALVTGPQSMLQLKSSQLSHAKEAVVKLGIIEKDVKVINTNMDDVSNNIELVAANMSNDTIAKIDSA
SIQTMIVVLVAIIVAVIVSFAVVNPLKRSLSQVNNALNVLASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRSLIIGILD
RSNQLAAAAEQTSAITAQTTSGIQEQKSQVDQVATATTELSSSAQQVSLSADQALEQIKQADQETQHMRAIAEENKLTIL
ALADEVAKAGVVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQVSTREIQ
QMIEVLQQGAEQAVAAMDMGRAQANACVEKTEQANIALETISQSVHKAYDSGTHIAHAAQEQNLVSQQVSEKLEHIAAIS
EETAIGADQTAQSSHQVAKLAEELQASVGEFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=30.9210526315789, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=29.8360655737705, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788194, Length=353, Percent_Identity=27.7620396600567, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787690, Length=354, Percent_Identity=28.5310734463277, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=335, Percent_Identity=29.5522388059701, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72199; Mature: 72199

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNVATRVIGGFGIVTLLLVVLGFTSYLTNNSLKASSAMMQELSLPALKSTNHLSETLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCHHHHHHHHH
EQQRQILIAYHTPKSANIPSIRKVFDDHGTQFKNEIANITQLVKSQPELTSLISQLSGSF
HHHHEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCH
SSFERDSLAMIAEREASLSKQEQLVNLKKKLENAADDASSELLDIVDLESSQNPDEQSLA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHH
ASASAIDTSLGNIITTIADLVTNEEDSKHELISKELDYIISETKNKLEYVNRHGQGIVEA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEH
NTLSSVTKDIEKVLALVTGPQSMLQLKSSQLSHAKEAVVKLGIIEKDVKVINTNMDDVSN
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
NIELVAANMSNDTIAKIDSASIQTMIVVLVAIIVAVIVSFAVVNPLKRSLSQVNNALNVL
CCEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRSLIIGILDRSNQLAAAAEQTSAITAQTT
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SGIQEQKSQVDQVATATTELSSSAQQVSLSADQALEQIKQADQETQHMRAIAEENKLTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ALADEVAKAGVVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAV
EEHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
VADEVRSLASRTQVSTREIQQMIEVLQQGAEQAVAAMDMGRAQANACVEKTEQANIALET
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISQSVHKAYDSGTHIAHAAQEQNLVSQQVSEKLEHIAAISEETAIGADQTAQSSHQVAKL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AEELQASVGEFRV
HHHHHHHHHCCCC
>Mature Secondary Structure
MKFNVATRVIGGFGIVTLLLVVLGFTSYLTNNSLKASSAMMQELSLPALKSTNHLSETLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCHHHHHHHHH
EQQRQILIAYHTPKSANIPSIRKVFDDHGTQFKNEIANITQLVKSQPELTSLISQLSGSF
HHHHEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCH
SSFERDSLAMIAEREASLSKQEQLVNLKKKLENAADDASSELLDIVDLESSQNPDEQSLA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHH
ASASAIDTSLGNIITTIADLVTNEEDSKHELISKELDYIISETKNKLEYVNRHGQGIVEA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEH
NTLSSVTKDIEKVLALVTGPQSMLQLKSSQLSHAKEAVVKLGIIEKDVKVINTNMDDVSN
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
NIELVAANMSNDTIAKIDSASIQTMIVVLVAIIVAVIVSFAVVNPLKRSLSQVNNALNVL
CCEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRSLIIGILDRSNQLAAAAEQTSAITAQTT
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SGIQEQKSQVDQVATATTELSSSAQQVSLSADQALEQIKQADQETQHMRAIAEENKLTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ALADEVAKAGVVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAV
EEHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
VADEVRSLASRTQVSTREIQQMIEVLQQGAEQAVAAMDMGRAQANACVEKTEQANIALET
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISQSVHKAYDSGTHIAHAAQEQNLVSQQVSEKLEHIAAISEETAIGADQTAQSSHQVAKL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AEELQASVGEFRV
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]