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The map label for this gene is apaH [H]

Identifier: 160874197

GI number: 160874197

Start: 1275338

End: 1276162

Strand: Reverse

Name: apaH [H]

Synonym: Sbal195_1077

Alternate gene names: 160874197

Gene position: 1276162-1275338 (Counterclockwise)

Preceding gene: 160874198

Following gene: 160874196

Centisome position: 23.87

GC content: 45.21

Gene sequence:

>825_bases
GTGGCGCATTATTTTGTTGGTGATATTCAAGGCTGTTTCGCTGAATTACAAAAATTACTCGCTAAGGTCGATTTTAATCC
CTCCCGTGATGAACTCTGGGCTGTAGGTGATCTTGTTGCTCGCGGACCAGATTCCTTAGCTACACTACGTTTTTTTCGTT
CTTTAGGTGATTCCGCTAAAACGGTTTTAGGCAATCACGATCTCCACTTAATGGCGTTACACGGCAAGCTCAAACGCGCT
AAGCCCAGCGATAATTTAACTGAAATTCTTGAATCGCCCGATATTTCAGCCTCAATTGATTGGCTGAGACAGCAACCCCT
AATGCGTGAATTACCCGAACACCAACTCATCATGAGTCATGCGGGTGTGCCACCGCAGTGGTCGCTTGAAGTATTAAGAG
AAGAAGCCGCACTCGTCAGTTGCGCACTCAAACAAGATGATTATCTTGAGGCACTGATAAGCCAAATGTATTCGGATAGT
GCCGAACAATGGGACCCAAGTGCAATTGGCATAGAGCGCCTACGTTACTGCATCAACGCATTAACACGCATGCGCTACCT
CTATGTCGATGGCCGACTCGATTTTGATTGTAAACAACCTCCTGAAAACTGTACTAATCCACAACTCAAACCTTGGTTTG
AGTTTGCTTCGCCCCTGCGCCAGAGCCACACCTTGGTTTTCGGCCATTGGGCAGCACTGATGGGCAATGTCGGCGATAGT
AAATTAAAGGCTTTAGATACAGGTTGTTGCTGGGGTGAACACTTAACCCTATGGCATCTTGAAAAAGACCAAAAAATTAC
GCAAAAAAAGTTAAAAAAGAGTTAA

Upstream 100 bases:

>100_bases
TATGGTCAGCGAATCGGGTGAGCATTTCCAAGCGACGATCCGTCCCTTCCGTTTAACGACCCCAGGCTTACTACATTAAT
ATCGTTAGGAAAGGGGTACT

Downstream 100 bases:

>100_bases
ACTAAAACAGCTTAAAGTCGATAACAGACTGAGCCGCCTAACCCTGAAATCGCCCTGTTTTCATTTGGAAAAATATAATA
AAAATCGGAGTATCCTATGA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MAHYFVGDIQGCFAELQKLLAKVDFNPSRDELWAVGDLVARGPDSLATLRFFRSLGDSAKTVLGNHDLHLMALHGKLKRA
KPSDNLTEILESPDISASIDWLRQQPLMRELPEHQLIMSHAGVPPQWSLEVLREEAALVSCALKQDDYLEALISQMYSDS
AEQWDPSAIGIERLRYCINALTRMRYLYVDGRLDFDCKQPPENCTNPQLKPWFEFASPLRQSHTLVFGHWAALMGNVGDS
KLKALDTGCCWGEHLTLWHLEKDQKITQKKLKKS

Sequences:

>Translated_274_residues
MAHYFVGDIQGCFAELQKLLAKVDFNPSRDELWAVGDLVARGPDSLATLRFFRSLGDSAKTVLGNHDLHLMALHGKLKRA
KPSDNLTEILESPDISASIDWLRQQPLMRELPEHQLIMSHAGVPPQWSLEVLREEAALVSCALKQDDYLEALISQMYSDS
AEQWDPSAIGIERLRYCINALTRMRYLYVDGRLDFDCKQPPENCTNPQLKPWFEFASPLRQSHTLVFGHWAALMGNVGDS
KLKALDTGCCWGEHLTLWHLEKDQKITQKKLKKS
>Mature_273_residues
AHYFVGDIQGCFAELQKLLAKVDFNPSRDELWAVGDLVARGPDSLATLRFFRSLGDSAKTVLGNHDLHLMALHGKLKRAK
PSDNLTEILESPDISASIDWLRQQPLMRELPEHQLIMSHAGVPPQWSLEVLREEAALVSCALKQDDYLEALISQMYSDSA
EQWDPSAIGIERLRYCINALTRMRYLYVDGRLDFDCKQPPENCTNPQLKPWFEFASPLRQSHTLVFGHWAALMGNVGDSK
LKALDTGCCWGEHLTLWHLEKDQKITQKKLKKS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=268, Percent_Identity=47.0149253731343, Blast_Score=261, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31128; Mature: 30997

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHYFVGDIQGCFAELQKLLAKVDFNPSRDELWAVGDLVARGPDSLATLRFFRSLGDSAK
CCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
TVLGNHDLHLMALHGKLKRAKPSDNLTEILESPDISASIDWLRQQPLMRELPEHQLIMSH
HHHCCCCEEEEEECCHHHCCCCCCHHHHHHCCCCCCHHHHHHHCCCHHHHCCHHHHHHHH
AGVPPQWSLEVLREEAALVSCALKQDDYLEALISQMYSDSAEQWDPSAIGIERLRYCINA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
LTRMRYLYVDGRLDFDCKQPPENCTNPQLKPWFEFASPLRQSHTLVFGHWAALMGNVGDS
HHHHHEEEECCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHCCCCCH
KLKALDTGCCWGEHLTLWHLEKDQKITQKKLKKS
HHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure 
AHYFVGDIQGCFAELQKLLAKVDFNPSRDELWAVGDLVARGPDSLATLRFFRSLGDSAK
CCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
TVLGNHDLHLMALHGKLKRAKPSDNLTEILESPDISASIDWLRQQPLMRELPEHQLIMSH
HHHCCCCEEEEEECCHHHCCCCCCHHHHHHCCCCCCHHHHHHHCCCHHHHCCHHHHHHHH
AGVPPQWSLEVLREEAALVSCALKQDDYLEALISQMYSDSAEQWDPSAIGIERLRYCINA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
LTRMRYLYVDGRLDFDCKQPPENCTNPQLKPWFEFASPLRQSHTLVFGHWAALMGNVGDS
HHHHHEEEECCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHCCCCCH
KLKALDTGCCWGEHLTLWHLEKDQKITQKKLKKS
HHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA