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The map label for this gene is argD [H]

Identifier: 159901066

GI number: 159901066

Start: 5830900

End: 5832114

Strand: Direct

Name: argD [H]

Synonym: Haur_4554

Alternate gene names: 159901066

Gene position: 5830900-5832114 (Clockwise)

Preceding gene: 159901064

Following gene: 159901067

Centisome position: 91.87

GC content: 50.95

Gene sequence:

>1215_bases
ATGACACAAAGCGAACACGAAGCGATTATTGCGCAGAGTGATACATTTTTGTTGCCGCTTTACAAACGAGCCAAACTCGC
TTTAGTTGGTGGCGAAGGCGCATGGTTACATGCTGCCGATGGACGACGTTTGTTGGATGCAACCGCAGGGATTGCGGTCA
ATGCCTTGGGTTATGGCGATGCTGAAGTGGTGGCTGCAATTCAACAAGCAGCAACAGGCTTGCTGCATACTTCAAATTTG
TATTACACTGCGTCGGTCGCCGAATTGGCCCAACGTTTGGTTGATTTAACCCCATGGGCTAGTAAGGCCTTTTTCTGCAA
TTCGGGTACCGAGGCGATTGAAGCTAGCCTGAAATTTGCCCGCCGCTATACCTACAACCAACGCCCTGAGCAACAAACGG
GCTTTGTGGCCTTTAACGATGCATTCCATGGTCGTTCGATGGGCGCGTTATCAGTTACCTCACGCGAGGCCTACCGTACT
CCTTTTAATCCATTAATCCCAGGCGTGCGCTTTATCAATCTTGAATGCGATCAAGCGACGCTCGAAGCGACAATCGATGC
GAGTGTTGCTGCCGTGATTGTTGAGCCAATTCAAGGTGAGGGCGGAATTCGGCCAATTAGCCCTGAATTTGCCCAGGCCT
TGCGCCGCCGTTGCGATCAAGTCGATGCCTTATTGATTTTCGATGAAATTCAATGTGGCATGGGCCGAACTGGCGATGTT
TGGGCACACCAAGCTTTGGGGGTCAATCCTGATATTATGGCGCTTGCCAAGCCGCTTGGTGGTGGTTTGCCGATTGGCGC
AGTCTTGGTTAACGAACGGGCAGCCAAAGCGTTGAATTATGGTGATCATGGCACAACCTTTGGTGGCAACCCCTTTATTT
GTAGCGTTGCCAACGTTGTTTTGCAAAAAGTTACCCATCCCACCATGTTGGATCATGTGCGCTCAGTTGGCGCAGAATTA
GGGGCAGGCCTGCGCGATTTAGGCGAACGCTTTGATGTAATTAGTGCTGTACGTGGGCGTGGCTTAATGTGGGGTGTTGA
ATTCCAAGGCCCAACGGCGGCCCACATTACCGAAGCAGCGTTTGATCAAGGCTTGTTGTTGGTTGGTTCGGGCGCTGATG
TCGTGCGGGTTATTCCACCATTGGTTATTGGACATAATGATGTTGAGCAGCTCATCACCCGTTTGGGCGATGCAATTAGC
CAAGTTGTGAGCTAA

Upstream 100 bases:

>100_bases
TCGGCTTTATGCTGACCTTGCCTTTTGATTTTTGGCTTTCAAGAAAGTGCTACAATGCACGCCAATTGATTGTTTGCTAG
CACGGGATGGAATCTAGGCC

Downstream 100 bases:

>100_bases
ATCTGGCTGAATGAAGGCACTCGGCTATCGGAATATTTTGGGGAATTGTAATGACTCCAACATCCGATAGCCAATGTGCT
TTTTTGATGGATCAGTAGAA

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTQSEHEAIIAQSDTFLLPLYKRAKLALVGGEGAWLHAADGRRLLDATAGIAVNALGYGDAEVVAAIQQAATGLLHTSNL
YYTASVAELAQRLVDLTPWASKAFFCNSGTEAIEASLKFARRYTYNQRPEQQTGFVAFNDAFHGRSMGALSVTSREAYRT
PFNPLIPGVRFINLECDQATLEATIDASVAAVIVEPIQGEGGIRPISPEFAQALRRRCDQVDALLIFDEIQCGMGRTGDV
WAHQALGVNPDIMALAKPLGGGLPIGAVLVNERAAKALNYGDHGTTFGGNPFICSVANVVLQKVTHPTMLDHVRSVGAEL
GAGLRDLGERFDVISAVRGRGLMWGVEFQGPTAAHITEAAFDQGLLLVGSGADVVRVIPPLVIGHNDVEQLITRLGDAIS
QVVS

Sequences:

>Translated_404_residues
MTQSEHEAIIAQSDTFLLPLYKRAKLALVGGEGAWLHAADGRRLLDATAGIAVNALGYGDAEVVAAIQQAATGLLHTSNL
YYTASVAELAQRLVDLTPWASKAFFCNSGTEAIEASLKFARRYTYNQRPEQQTGFVAFNDAFHGRSMGALSVTSREAYRT
PFNPLIPGVRFINLECDQATLEATIDASVAAVIVEPIQGEGGIRPISPEFAQALRRRCDQVDALLIFDEIQCGMGRTGDV
WAHQALGVNPDIMALAKPLGGGLPIGAVLVNERAAKALNYGDHGTTFGGNPFICSVANVVLQKVTHPTMLDHVRSVGAEL
GAGLRDLGERFDVISAVRGRGLMWGVEFQGPTAAHITEAAFDQGLLLVGSGADVVRVIPPLVIGHNDVEQLITRLGDAIS
QVVS
>Mature_403_residues
TQSEHEAIIAQSDTFLLPLYKRAKLALVGGEGAWLHAADGRRLLDATAGIAVNALGYGDAEVVAAIQQAATGLLHTSNLY
YTASVAELAQRLVDLTPWASKAFFCNSGTEAIEASLKFARRYTYNQRPEQQTGFVAFNDAFHGRSMGALSVTSREAYRTP
FNPLIPGVRFINLECDQATLEATIDASVAAVIVEPIQGEGGIRPISPEFAQALRRRCDQVDALLIFDEIQCGMGRTGDVW
AHQALGVNPDIMALAKPLGGGLPIGAVLVNERAAKALNYGDHGTTFGGNPFICSVANVVLQKVTHPTMLDHVRSVGAELG
AGLRDLGERFDVISAVRGRGLMWGVEFQGPTAAHITEAAFDQGLLLVGSGADVVRVIPPLVIGHNDVEQLITRLGDAISQ
VVS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=31.7829457364341, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=34.5514950166113, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=27.8801843317972, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=25.5980861244019, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=25.1219512195122, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI226442705, Length=409, Percent_Identity=24.9388753056235, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI226442709, Length=372, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=26.3888888888889, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=26.3888888888889, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=26.3888888888889, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1788044, Length=395, Percent_Identity=40.253164556962, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1789759, Length=396, Percent_Identity=37.3737373737374, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI145693181, Length=366, Percent_Identity=38.7978142076503, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=34.0050377833753, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=32.8282828282828, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=30.3827751196172, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786349, Length=333, Percent_Identity=28.5285285285285, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=30.6701030927835, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI25144274, Length=253, Percent_Identity=33.9920948616601, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32564660, Length=442, Percent_Identity=28.5067873303167, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=25.9615384615385, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=410, Percent_Identity=29.5121951219512, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=168, Percent_Identity=25.5952380952381, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324432, Length=407, Percent_Identity=41.2776412776413, Blast_Score=312, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6323470, Length=389, Percent_Identity=30.0771208226221, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=307, Percent_Identity=28.0130293159609, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=424, Percent_Identity=21.6981132075472, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357415, Length=393, Percent_Identity=30.7888040712468, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574759, Length=459, Percent_Identity=30.0653594771242, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI161085790, Length=456, Percent_Identity=30.2631578947368, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21356575, Length=429, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281366494, Length=292, Percent_Identity=27.7397260273973, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667139, Length=292, Percent_Identity=27.7397260273973, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667143, Length=292, Percent_Identity=27.7397260273973, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43022; Mature: 42891

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSEHEAIIAQSDTFLLPLYKRAKLALVGGEGAWLHAADGRRLLDATAGIAVNALGYGD
CCCCCCCEEEECCCCEEEECCCCCEEEEECCCCCEEECCCCCEEHHHHCCEEEEECCCCH
AEVVAAIQQAATGLLHTSNLYYTASVAELAQRLVDLTPWASKAFFCNSGTEAIEASLKFA
HHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
RRYTYNQRPEQQTGFVAFNDAFHGRSMGALSVTSREAYRTPFNPLIPGVRFINLECDQAT
HHHCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCHHHCCCCCHHCCCEEEEEEECCCHH
LEATIDASVAAVIVEPIQGEGGIRPISPEFAQALRRRCDQVDALLIFDEIQCGMGRTGDV
HHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHCCCCCCCCH
WAHQALGVNPDIMALAKPLGGGLPIGAVLVNERAAKALNYGDHGTTFGGNPFICSVANVV
HHHHHCCCCCHHHHHHHHCCCCCCCHHEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LQKVTHPTMLDHVRSVGAELGAGLRDLGERFDVISAVRGRGLMWGVEFQGPTAAHITEAA
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
FDQGLLLVGSGADVVRVIPPLVIGHNDVEQLITRLGDAISQVVS
HCCCEEEEECCCCHHHHCCCCEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQSEHEAIIAQSDTFLLPLYKRAKLALVGGEGAWLHAADGRRLLDATAGIAVNALGYGD
CCCCCCEEEECCCCEEEECCCCCEEEEECCCCCEEECCCCCEEHHHHCCEEEEECCCCH
AEVVAAIQQAATGLLHTSNLYYTASVAELAQRLVDLTPWASKAFFCNSGTEAIEASLKFA
HHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
RRYTYNQRPEQQTGFVAFNDAFHGRSMGALSVTSREAYRTPFNPLIPGVRFINLECDQAT
HHHCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCHHHCCCCCHHCCCEEEEEEECCCHH
LEATIDASVAAVIVEPIQGEGGIRPISPEFAQALRRRCDQVDALLIFDEIQCGMGRTGDV
HHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHCCCCCCCCH
WAHQALGVNPDIMALAKPLGGGLPIGAVLVNERAAKALNYGDHGTTFGGNPFICSVANVV
HHHHHCCCCCHHHHHHHHCCCCCCCHHEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LQKVTHPTMLDHVRSVGAELGAGLRDLGERFDVISAVRGRGLMWGVEFQGPTAAHITEAA
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
FDQGLLLVGSGADVVRVIPPLVIGHNDVEQLITRLGDAISQVVS
HCCCEEEEECCCCHHHHCCCCEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]