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The map label for this gene is yybE [H]

Identifier: 159899971

GI number: 159899971

Start: 4343842

End: 4344738

Strand: Direct

Name: yybE [H]

Synonym: Haur_3454

Alternate gene names: 159899971

Gene position: 4343842-4344738 (Clockwise)

Preceding gene: 159899969

Following gene: 159899978

Centisome position: 68.44

GC content: 56.08

Gene sequence:

>897_bases
ATGGAATTAAGCCAATTGCGCTATTTTGAGGCGGTGGCTCGCTTGGGCAATGTGACGAAGGCCGCCCACGAACAACACAT
CGCCCAACCATCGCTAAGCAAAGCCTTACGAGCGCTTGAGCAAGAATTAGGGGTACATTTGTTTGATCGGGTTGGCCGAG
GGGTTGAATTAAGCGATGCTGGCAAATTATTGTTGCCCTATGCGCGACGCGTCTTGGCCGAACTTCAAGCAGCCCGCCAT
GCCTTACAATCTCGTGCTGATCTGACGGTGGGCCATGTCTCGTTGGGAGTTACGCCAACCGTGGGCACGCGGCTCATTCC
CCAAGCCTTGGCCGCTTTCAATCGGCGCTATCGCGGGATTCAGCTTGAATTGCACGAGGCCGGAGCCAGCGAGTTGGTCG
AATTGCTCAATGCTGGGGTGGTCGATTTGGCGATTGTTTCGGCCTTGGTGCATGGAGTTGAATCAACAACCTTGATGAGC
GAGCCGTTGGTGGTGGCGGTTGGTTTACAACATCGTTTTGCCCAACGCCAGAGCATTGCCGCCAACGAGCTACGTGATGA
GGGCTTTATTTTGTTTCCGCAGGGCTACGAGCTGCGCAATTATACCTTGCAACTTTGCGAGCAAGCAGGCTTCGCCCCGC
GAATTGTGCTCGATGGCGGCGAGATGGATACGGTGGTGAGTTTGGTTGCCGCAGGCTTGGGCGTGGCGGTTGTGCCTCAA
TTAGCCATCGATCAGCGCATGGGCTTGCATGCCTTGATGATCGACGCTGGCGGATTGCAACGCACCTTGCGGCTGATCCG
CCATAGTCAACGCCAACCCTCGCCTGCTGCCGCCGCCCTACATCGGGTGCTGCACGAATGGGTCAGCCAACATTATCCCA
GTGCTTCAGCAAATTGA

Upstream 100 bases:

>100_bases
TTGTTGTTGTTAAACACTCTACCGTTAACAAATCGCTACGTCTAAGATATGATTGCTCTAGGAATCATAGCCTTGGGCTA
TCAATTATCAAGGAGCAACC

Downstream 100 bases:

>100_bases
CGTGAAAGCGCTTTGGCTCCTTGACTCATCCATGGCTTGACTGGAGTGAATTTTAATATTTCCAACGGTGCAGGAATATA
GCCGCCGCACATTCGGTTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MELSQLRYFEAVARLGNVTKAAHEQHIAQPSLSKALRALEQELGVHLFDRVGRGVELSDAGKLLLPYARRVLAELQAARH
ALQSRADLTVGHVSLGVTPTVGTRLIPQALAAFNRRYRGIQLELHEAGASELVELLNAGVVDLAIVSALVHGVESTTLMS
EPLVVAVGLQHRFAQRQSIAANELRDEGFILFPQGYELRNYTLQLCEQAGFAPRIVLDGGEMDTVVSLVAAGLGVAVVPQ
LAIDQRMGLHALMIDAGGLQRTLRLIRHSQRQPSPAAAALHRVLHEWVSQHYPSASAN

Sequences:

>Translated_298_residues
MELSQLRYFEAVARLGNVTKAAHEQHIAQPSLSKALRALEQELGVHLFDRVGRGVELSDAGKLLLPYARRVLAELQAARH
ALQSRADLTVGHVSLGVTPTVGTRLIPQALAAFNRRYRGIQLELHEAGASELVELLNAGVVDLAIVSALVHGVESTTLMS
EPLVVAVGLQHRFAQRQSIAANELRDEGFILFPQGYELRNYTLQLCEQAGFAPRIVLDGGEMDTVVSLVAAGLGVAVVPQ
LAIDQRMGLHALMIDAGGLQRTLRLIRHSQRQPSPAAAALHRVLHEWVSQHYPSASAN
>Mature_298_residues
MELSQLRYFEAVARLGNVTKAAHEQHIAQPSLSKALRALEQELGVHLFDRVGRGVELSDAGKLLLPYARRVLAELQAARH
ALQSRADLTVGHVSLGVTPTVGTRLIPQALAAFNRRYRGIQLELHEAGASELVELLNAGVVDLAIVSALVHGVESTTLMS
EPLVVAVGLQHRFAQRQSIAANELRDEGFILFPQGYELRNYTLQLCEQAGFAPRIVLDGGEMDTVVSLVAAGLGVAVVPQ
LAIDQRMGLHALMIDAGGLQRTLRLIRHSQRQPSPAAAALHRVLHEWVSQHYPSASAN

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=282, Percent_Identity=35.1063829787234, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=31.3008130081301, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787879, Length=244, Percent_Identity=31.5573770491803, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787530, Length=263, Percent_Identity=27.3764258555133, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=28.5211267605634, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788887, Length=250, Percent_Identity=32.4, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=27.9166666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=32.4, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787806, Length=255, Percent_Identity=29.4117647058824, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788748, Length=288, Percent_Identity=28.4722222222222, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789204, Length=247, Percent_Identity=27.1255060728745, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=28.9655172413793, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788296, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788481, Length=288, Percent_Identity=28.125, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081904, Length=214, Percent_Identity=26.6355140186916, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790208, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790262, Length=303, Percent_Identity=22.4422442244224, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787949, Length=140, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=137, Percent_Identity=28.4671532846715, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994962, Length=152, Percent_Identity=30.9210526315789, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32340; Mature: 32340

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSQLRYFEAVARLGNVTKAAHEQHIAQPSLSKALRALEQELGVHLFDRVGRGVELSDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCCCCEECCC
GKLLLPYARRVLAELQAARHALQSRADLTVGHVSLGVTPTVGTRLIPQALAAFNRRYRGI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCE
QLELHEAGASELVELLNAGVVDLAIVSALVHGVESTTLMSEPLVVAVGLQHRFAQRQSIA
EEEEHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
ANELRDEGFILFPQGYELRNYTLQLCEQAGFAPRIVLDGGEMDTVVSLVAAGLGVAVVPQ
HHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHH
LAIDQRMGLHALMIDAGGLQRTLRLIRHSQRQPSPAAAALHRVLHEWVSQHYPSASAN
HHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELSQLRYFEAVARLGNVTKAAHEQHIAQPSLSKALRALEQELGVHLFDRVGRGVELSDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCCCCCEECCC
GKLLLPYARRVLAELQAARHALQSRADLTVGHVSLGVTPTVGTRLIPQALAAFNRRYRGI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCE
QLELHEAGASELVELLNAGVVDLAIVSALVHGVESTTLMSEPLVVAVGLQHRFAQRQSIA
EEEEHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
ANELRDEGFILFPQGYELRNYTLQLCEQAGFAPRIVLDGGEMDTVVSLVAAGLGVAVVPQ
HHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHH
LAIDQRMGLHALMIDAGGLQRTLRLIRHSQRQPSPAAAALHRVLHEWVSQHYPSASAN
HHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]