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The map label for this gene is csd [H]

Identifier: 159899693

GI number: 159899693

Start: 4012946

End: 4014424

Strand: Direct

Name: csd [H]

Synonym: Haur_3175

Alternate gene names: 159899693

Gene position: 4012946-4014424 (Clockwise)

Preceding gene: 159899688

Following gene: 159899694

Centisome position: 63.23

GC content: 51.39

Gene sequence:

>1479_bases
ATGCACGAACTTGCTAGCCACTTCGCAGCTTTTCGCCGTCAGATTGTTGGTATTGATCAGCATTTTATGACACCTTATGG
CTCGCTGCCAATAGTTTATGCCGATTGGACAGCAAGTGGGCGTTTGTATGCGCCAATCGAGTTGCAAATGCTGAATGTGT
TTGGGCCGTTTGTCGGCAATACCCACTCCGAATCGAATATCACTGGAACCTCGATGACCGAAGCCTACCATTTTGCCCAA
CGTTTGATCAAGCAGCATGTTAACGCCGCCAGCGATGATGTGTTGATTTTAGCTGGCTCAGGCATGACTGCTGTGGTCAA
TAAGTTTCAGCGGATTTTGGGTTTGCGCATGCCCGAACAATGGGCTGAGCAGATTAAGTTCTCGAAAAACGAGCGGCCTG
TTGTGTTCATCTCACATATGGAGCATCACTCCAACCATACCTCATGGCTCGAAACCATCGCCGAGGTCGTGGTTGTGCCG
CCCGATGATCAAGGGCTGATCGATCCAGCCAATTTGGAAGCCTTGCTGCCTGCCTATGCTGAACGCAGCGTTAAAATCGG
AGCCTTCACTGCTTGCTCAAATGTGACTGGTGTGCGCACGCTCTACCACGAGTTGGCGCGGGTGATGCATGCTCACGGTG
GGGTTTGTTTTATTGATTTTGCGGCTTCAGCGCCCTATGTTGAAATCGATATGCACCCAGCCGACCCAGCCGCCGCGCTT
GATGCGATTTATTTCTCGCCGCATAAATGTTTGGGCGGCCCGGCCACGCCTGGGGTTTTGATTTTTAGCAGCAAACTCTA
CCACAATCGGGTACCTGATCAGCCTGGCGGTGGCACGGTCAACTGGACGAACCCGTGGATGGGCCATAGTTTTGTCAGCG
ATATCGAAGCACGTGAAGATGGTGGTACTCCCGCCTTTTTACAAACGATCAAAGCGGCGCTGGCCTTCCAACTCAAGCAA
ACCATGGGCGTTGAGCAGATCGAAGCCCGCGAAGCCCAATTGACCAAACGTCTATTCCAAGGCTTGCGCTCAATCGATGG
CATTCATCTGCTAGCTGATCACTTGGAACAAAGACAAGGGATCTTTTCGTTCTACATTGAGAATTTGCACTACAACTTGA
TTGTACAATTGCTGAACGATCGTTTTGGGGTGCAAGTGCGTGGCGGATGTTCCTGCGCTGGAACCTATGGCCATTATCTC
TTGCACGTCGATCCGCAGCGCTCCAAACGCATCACCGATTTAATCGATCAAGGCGATTTATCGGATAAACCAGGCTGGGT
ACGGCTTTCGATCCACCCAACCACCACCGATCACGAGGCCGATTATCTGATCGATGCGCTGGATCAAGTGGTGCGCAATG
GCTCGGCGTGGGCCGACGATTATCAATATTCGAATAAAACCAATGAATGGCGGCATCGCCGACCAGTTCAGCAGGATATA
GGAGCGTGGTTTCAGTGTTGCGATTTGGTCGAGCATTAA

Upstream 100 bases:

>100_bases
ATAGCATAGCCCTCTTGTCGCTAGCAGGGTTCGCCGTCTATAATTCAGGCATTGGGCAAACAACCAGCGATGGTCGCAAC
GAGGCGACTAAGGAGCATGT

Downstream 100 bases:

>100_bases
TTGAATTTGGGCGAGGCTTGGTTGGTTGGCTGGGGCTATTTAATTTGCTGAGTGCGCTCGCCAACCTGCCCAACCTTGGC
TGGCTAGCGCAACGTCGGCG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MHELASHFAAFRRQIVGIDQHFMTPYGSLPIVYADWTASGRLYAPIELQMLNVFGPFVGNTHSESNITGTSMTEAYHFAQ
RLIKQHVNAASDDVLILAGSGMTAVVNKFQRILGLRMPEQWAEQIKFSKNERPVVFISHMEHHSNHTSWLETIAEVVVVP
PDDQGLIDPANLEALLPAYAERSVKIGAFTACSNVTGVRTLYHELARVMHAHGGVCFIDFAASAPYVEIDMHPADPAAAL
DAIYFSPHKCLGGPATPGVLIFSSKLYHNRVPDQPGGGTVNWTNPWMGHSFVSDIEAREDGGTPAFLQTIKAALAFQLKQ
TMGVEQIEAREAQLTKRLFQGLRSIDGIHLLADHLEQRQGIFSFYIENLHYNLIVQLLNDRFGVQVRGGCSCAGTYGHYL
LHVDPQRSKRITDLIDQGDLSDKPGWVRLSIHPTTTDHEADYLIDALDQVVRNGSAWADDYQYSNKTNEWRHRRPVQQDI
GAWFQCCDLVEH

Sequences:

>Translated_492_residues
MHELASHFAAFRRQIVGIDQHFMTPYGSLPIVYADWTASGRLYAPIELQMLNVFGPFVGNTHSESNITGTSMTEAYHFAQ
RLIKQHVNAASDDVLILAGSGMTAVVNKFQRILGLRMPEQWAEQIKFSKNERPVVFISHMEHHSNHTSWLETIAEVVVVP
PDDQGLIDPANLEALLPAYAERSVKIGAFTACSNVTGVRTLYHELARVMHAHGGVCFIDFAASAPYVEIDMHPADPAAAL
DAIYFSPHKCLGGPATPGVLIFSSKLYHNRVPDQPGGGTVNWTNPWMGHSFVSDIEAREDGGTPAFLQTIKAALAFQLKQ
TMGVEQIEAREAQLTKRLFQGLRSIDGIHLLADHLEQRQGIFSFYIENLHYNLIVQLLNDRFGVQVRGGCSCAGTYGHYL
LHVDPQRSKRITDLIDQGDLSDKPGWVRLSIHPTTTDHEADYLIDALDQVVRNGSAWADDYQYSNKTNEWRHRRPVQQDI
GAWFQCCDLVEH
>Mature_492_residues
MHELASHFAAFRRQIVGIDQHFMTPYGSLPIVYADWTASGRLYAPIELQMLNVFGPFVGNTHSESNITGTSMTEAYHFAQ
RLIKQHVNAASDDVLILAGSGMTAVVNKFQRILGLRMPEQWAEQIKFSKNERPVVFISHMEHHSNHTSWLETIAEVVVVP
PDDQGLIDPANLEALLPAYAERSVKIGAFTACSNVTGVRTLYHELARVMHAHGGVCFIDFAASAPYVEIDMHPADPAAAL
DAIYFSPHKCLGGPATPGVLIFSSKLYHNRVPDQPGGGTVNWTNPWMGHSFVSDIEAREDGGTPAFLQTIKAALAFQLKQ
TMGVEQIEAREAQLTKRLFQGLRSIDGIHLLADHLEQRQGIFSFYIENLHYNLIVQLLNDRFGVQVRGGCSCAGTYGHYL
LHVDPQRSKRITDLIDQGDLSDKPGWVRLSIHPTTTDHEADYLIDALDQVVRNGSAWADDYQYSNKTNEWRHRRPVQQDI
GAWFQCCDLVEH

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=332, Percent_Identity=25.3012048192771, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789175, Length=410, Percent_Identity=25.3658536585366, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211090, Length=478, Percent_Identity=30.3347280334728, Blast_Score=229, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 54977; Mature: 54977

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELASHFAAFRRQIVGIDQHFMTPYGSLPIVYADWTASGRLYAPIELQMLNVFGPFVGN
CCHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEECCCCEEECCCEEEEHHHHCCCCCC
THSESNITGTSMTEAYHFAQRLIKQHVNAASDDVLILAGSGMTAVVNKFQRILGLRMPEQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHH
WAEQIKFSKNERPVVFISHMEHHSNHTSWLETIAEVVVVPPDDQGLIDPANLEALLPAYA
HHHHHHCCCCCCCEEEEECCHHCCCHHHHHHHHHCEEEECCCCCCCCCCCCHHHHHHHHH
ERSVKIGAFTACSNVTGVRTLYHELARVMHAHGGVCFIDFAASAPYVEIDMHPADPAAAL
HCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHH
DAIYFSPHKCLGGPATPGVLIFSSKLYHNRVPDQPGGGTVNWTNPWMGHSFVSDIEARED
HHHHCCCHHHCCCCCCCCEEEEECHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHCC
GGTPAFLQTIKAALAFQLKQTMGVEQIEAREAQLTKRLFQGLRSIDGIHLLADHLEQRQG
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
IFSFYIENLHYNLIVQLLNDRFGVQVRGGCSCAGTYGHYLLHVDPQRSKRITDLIDQGDL
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCEEEEEECCHHHHHHHHHHHCCCC
SDKPGWVRLSIHPTTTDHEADYLIDALDQVVRNGSAWADDYQYSNKTNEWRHRRPVQQDI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHH
GAWFQCCDLVEH
HHHHHHHHHHCC
>Mature Secondary Structure
MHELASHFAAFRRQIVGIDQHFMTPYGSLPIVYADWTASGRLYAPIELQMLNVFGPFVGN
CCHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEECCCCEEECCCEEEEHHHHCCCCCC
THSESNITGTSMTEAYHFAQRLIKQHVNAASDDVLILAGSGMTAVVNKFQRILGLRMPEQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHH
WAEQIKFSKNERPVVFISHMEHHSNHTSWLETIAEVVVVPPDDQGLIDPANLEALLPAYA
HHHHHHCCCCCCCEEEEECCHHCCCHHHHHHHHHCEEEECCCCCCCCCCCCHHHHHHHHH
ERSVKIGAFTACSNVTGVRTLYHELARVMHAHGGVCFIDFAASAPYVEIDMHPADPAAAL
HCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHH
DAIYFSPHKCLGGPATPGVLIFSSKLYHNRVPDQPGGGTVNWTNPWMGHSFVSDIEARED
HHHHCCCHHHCCCCCCCCEEEEECHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHCC
GGTPAFLQTIKAALAFQLKQTMGVEQIEAREAQLTKRLFQGLRSIDGIHLLADHLEQRQG
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
IFSFYIENLHYNLIVQLLNDRFGVQVRGGCSCAGTYGHYLLHVDPQRSKRITDLIDQGDL
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCEEEEEECCHHHHHHHHHHHCCCC
SDKPGWVRLSIHPTTTDHEADYLIDALDQVVRNGSAWADDYQYSNKTNEWRHRRPVQQDI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHH
GAWFQCCDLVEH
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA