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The map label for this gene is hetI [H]

Identifier: 159899648

GI number: 159899648

Start: 3956053

End: 3956766

Strand: Direct

Name: hetI [H]

Synonym: Haur_3130

Alternate gene names: 159899648

Gene position: 3956053-3956766 (Clockwise)

Preceding gene: 159899647

Following gene: 159899649

Centisome position: 62.33

GC content: 55.04

Gene sequence:

>714_bases
ATGATCCTATGTTCTATGCTCTTAAGCCCTAACACTATCGACATTTGGTTGCTTGATTTGACGCGGCTGCGACCCCAACG
TAGCCGCTTTTGGGCTGTGCTCAACGTCGAGGAGCAAGCGCGGGCCTTGCGCTTTCACTTCGAGCATGATCAAGTGCGCT
ACACGATTTGCCGTGGAGCAATGCGCCTGATTTTGGCCGAATACCTTGGCCGCGACCCAAGCAGCCTCGAATTTAGCCAA
AACAACTATGGCAAGCCCTTATTGGCCGATGTCGATTTGAGCTTTAACCTCTCACATGCTGGCAACTACGGCATGCTTGG
CCTCAGCCAACTTGCCACCATCGGCGTGGATATCGAAGAACAACGCCAGCTTGACGATTTGGCAGGGATTGCTCAGCATT
ATTTTGCCCCCAGCGAACGCCAAGCAGTGCTGAATGCTGATGATCAGACCGCCGCCTTTTTTCGCTGTTGGACGCGCAAA
GAAGCCTATATCAAAGCCCATGGAATGGGCTTGTCGCTACCACTCTCCAGCTTTGCCGTCTCGATCGAGCCAGAAATTGC
CCAAGCCCTCGAATGGAACCGCGAAAACACCGTCGCTCAATGGCATGTCCAGCCGCTCAGTGCGCCCGCTGGCTACGCCG
CCGCGCTCGCTTGCCCTCGCTCGACCGAAGAAATATTTGTGCAGCAGCGTGAGTGGCTGGGCTTGGCTGAGTAA

Upstream 100 bases:

>100_bases
AAATCAAAAAAGCTCAGTTATAACCGCGAAGAACGCGAAGTTGCGCTAAGAGATAAAAAATTAAACATTCTTCGTGCGCT
TCGTGTCCTTCGTGGATCAA

Downstream 100 bases:

>100_bases
ATCGTCGAAGCCTGATTTTTTGTCAAGCCGCCAGCCCTGTGTTAAAATGCGCTATTGCGTTGAACACGCACTAGCTTGAA
GGGCTTTTGATGCAGCGGTT

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MILCSMLLSPNTIDIWLLDLTRLRPQRSRFWAVLNVEEQARALRFHFEHDQVRYTICRGAMRLILAEYLGRDPSSLEFSQ
NNYGKPLLADVDLSFNLSHAGNYGMLGLSQLATIGVDIEEQRQLDDLAGIAQHYFAPSERQAVLNADDQTAAFFRCWTRK
EAYIKAHGMGLSLPLSSFAVSIEPEIAQALEWNRENTVAQWHVQPLSAPAGYAAALACPRSTEEIFVQQREWLGLAE

Sequences:

>Translated_237_residues
MILCSMLLSPNTIDIWLLDLTRLRPQRSRFWAVLNVEEQARALRFHFEHDQVRYTICRGAMRLILAEYLGRDPSSLEFSQ
NNYGKPLLADVDLSFNLSHAGNYGMLGLSQLATIGVDIEEQRQLDDLAGIAQHYFAPSERQAVLNADDQTAAFFRCWTRK
EAYIKAHGMGLSLPLSSFAVSIEPEIAQALEWNRENTVAQWHVQPLSAPAGYAAALACPRSTEEIFVQQREWLGLAE
>Mature_237_residues
MILCSMLLSPNTIDIWLLDLTRLRPQRSRFWAVLNVEEQARALRFHFEHDQVRYTICRGAMRLILAEYLGRDPSSLEFSQ
NNYGKPLLADVDLSFNLSHAGNYGMLGLSQLATIGVDIEEQRQLDDLAGIAQHYFAPSERQAVLNADDQTAAFFRCWTRK
EAYIKAHGMGLSLPLSSFAVSIEPEIAQALEWNRENTVAQWHVQPLSAPAGYAAALACPRSTEEIFVQQREWLGLAE

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Drosophila melanogaster, GI24663173, Length=244, Percent_Identity=27.4590163934426, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 26796; Mature: 26796

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILCSMLLSPNTIDIWLLDLTRLRPQRSRFWAVLNVEEQARALRFHFEHDQVRYTICRGA
CEEEEEECCCCEEEEEEEEHHHCCCCCCCEEEEEEHHHHHHHEEEEECCCHHHHHHHHHH
MRLILAEYLGRDPSSLEFSQNNYGKPLLADVDLSFNLSHAGNYGMLGLSQLATIGVDIEE
HHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHCCCHHH
QRQLDDLAGIAQHYFAPSERQAVLNADDQTAAFFRCWTRKEAYIKAHGMGLSLPLSSFAV
HHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCEECCHHHEEE
SIEPEIAQALEWNRENTVAQWHVQPLSAPAGYAAALACPRSTEEIFVQQREWLGLAE
EECHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MILCSMLLSPNTIDIWLLDLTRLRPQRSRFWAVLNVEEQARALRFHFEHDQVRYTICRGA
CEEEEEECCCCEEEEEEEEHHHCCCCCCCEEEEEEHHHHHHHEEEEECCCHHHHHHHHHH
MRLILAEYLGRDPSSLEFSQNNYGKPLLADVDLSFNLSHAGNYGMLGLSQLATIGVDIEE
HHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHCCCHHH
QRQLDDLAGIAQHYFAPSERQAVLNADDQTAAFFRCWTRKEAYIKAHGMGLSLPLSSFAV
HHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCEECCHHHEEE
SIEPEIAQALEWNRENTVAQWHVQPLSAPAGYAAALACPRSTEEIFVQQREWLGLAE
EECHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]