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The map label for this gene is lgrB [H]

Identifier: 159899647

GI number: 159899647

Start: 3950482

End: 3955932

Strand: Direct

Name: lgrB [H]

Synonym: Haur_3129

Alternate gene names: 159899647

Gene position: 3950482-3955932 (Clockwise)

Preceding gene: 159899646

Following gene: 159899648

Centisome position: 62.25

GC content: 53.09

Gene sequence:

>5451_bases
ATGACCGAAGTCGCACGCCAGCTTGAAGATCTTTCGCCCGAACGCCGCGCCTTGTTGGCCCAACGTCTGCGCCAACGCCA
AGCCGCCAAGCCAGTGCCCAGCATTCCAGCGCTGGCTCGGATCGGCGAACATCCAGCCTTTGAACTTTCGTTTGCCCAAC
AACGGCTGTGGTTTTTAAGCCAGTGGCAACCAGAAAGCGCCGCCTATCACATTCCAGCCACATTTAGCATTGCTGGTGAA
ATTAATGTTTCTGTATTGCAAACTTGTCTTGATAAAATTATTCAGCGCCATGAAGTGCTGCGTAGCACGATCGAAGTGCT
CAACGACCAGCCAATGCAGGTTATTCAGCCATTCCGCAGCCTTGATTTGGAGCTTGTTGATCTCCGTGGGCTGAGCAATG
AGCAACAAGCCAGTCAACGCCAGCAGCAGATCGAACGCCACAGTCAGCAGCCGTTTGATCTCAGCAAAGATTTAATGCTA
CGCGGATTGTTGCTGCACACGGCTGCTGATCACGCTGAATTGGTATTGACGATTCACCATATTGCCTGCGATGGTTGGTC
GATTGGGGTCTTGTTGCGTGAGCTAGGCCAACTTTACGAAGCTGGGCTACGCGGCGAGCAACTTGAGCTACCAGCGCTGC
CAATTCAATATGCCGATTTTGCGGTTTGGCATAAACGTTATGTGCTTGAGCAAGTGTATCAGCAACATTTAAATTTTTGG
CAAGAACAATTAAGCGGCACGCTACCCTTGCTCAATTTGCCAACCGACCATGCGCGACCAGCGGTCAAACGCGACCTTGG
GGCAACCGTCGAATATCATCTACCTTGGAGTTTGGTCGAGGCGGTTGAGCGCTTGAGCCGCCAAGAGCGAGCCACGCCGT
TTATGCTGTTTATGGCGGCTTTTCAGGTTTTGCTCTATCGCTATTCAGGCCAAAGCGATCTGATTATTGGTACGCCGATT
GCCAATCGCACCCGCCGCGAAATCGAAAATCTGATTGGATTTTTCGTCAATACCTTGCCAATTCGGGTCAATTTGGCTGG
CTCGCCTAGCTTTCGTAGCCTAATTGCCCAAGTGCGCCAAACCTCGTTGGCCGCTTTCGAGCATCAAGATATGCCGCTCG
AACACTTGATTGATGTGCTCAAAGTCGAACGCAGTTTGAGCCATAACCCACTGTTTCAAGCCCTGTTTGTGCATCAAACC
ACCAGCATCCAAACTGTCGATTCAGGTGAATTTGGCTTGCAATTTGGCGGGGCAATTGAAACTGGCAGCGCTAAATTTGA
TATTAATCTGAATTTGGCCGCCAATCGTGCCACTTTTGAATACAATACCGATCTGTTTGAGCGCAGCACGATCGAACGCA
TGGCCAGCCATTTCCATAGCTTGTTGGAATATGCGGTGACCAATCCCGATGCCAGCATCGAGCATTTGCCTTTGCTGAGC
AGCAGCGAACGCCAACAATTGCTGCAAACCTGGAACAGCACCAGCGCCAATTATCCTGCGGTTGATTCGATTGTGCGTTT
GTTCGAAGCTCAAGCGGCGCGAGTCCCAGAGCGCACGGCCTTGCATTTTGAAGGCCAAACCCTGAGCTACGCCGAATTGA
ATCAACGCGCCAACCAACTAGCACATAGCTTGCGCCAACGCGGCATCGGCTGCGATATGCGAGTAGGCTTGTTTATCGAT
CGCTCGTTGGATTTATTGGTTGGCGCGTTGGGAATTCTCAAAGCGGGCGCGGCCTATGTGCCAATCGACCCAATTTACCC
CCAAGATCGCATCAGCGCTATGCTCGAAGATGGTGCAGTGAGTTTGCTGCTTACCCACGCTGAGCTAGCCGCCGAATTGC
CAAAACTTGATCTTGAGGTGCTGTGCCTCGACCAAGCATGGCCGACGATTGCCCAAGCGCCAACGCACAACTTGAATTTG
GCGCTTGAGCCGCGCAGTTTGATGTATGTGCTGTTTACCTCTGGCTCGACTGGCCGCCCCAAAGGTGTGGCAATCGAACA
CCATAATTATGTCAACTATATTCAAGGCTTATTGCAACGAATTGAAGCCGAAGATGGCTGGAGCTATGCCTTGGTTTCGA
CCTTCGCGGCAGATCTTGGCACAACCAATGTGTATGGAGCCTTGTGCAGCGGCGGCGAATTACATATCGTGGCCTATGAA
CGCGCCACTGATCCCGAAGCGTTTGCAGCCTACTTTCGCCAGCATCGCATCGATGTGATGAAACTTGTACCCAGCCATTT
CGAGGCCATGCGCGGCTTGAACAACTTGGCCGATGTCATTCCCAAGCAGCGCTTGATTTTGGCGGGCGAAGCCAGCCTTT
GGGAGCAGCTTAGCGATATTCGCCAACTTCAGCCTAGCGTGCAACTGCAAAACCACTATGGACCAACCGAAACCACGGTT
TCCATGCTGACCTATCCAATTCCCAGCCAACCACACTACCCCAGCAGCACCGTGCCACTTGGCAGGCCATTGGGCAATGT
GCAAATTTATGTGCTCGATCGCCGAATGCAGCCAACGCCGCAAGGTGTACCAGGCGAACTCTACGTTGGCGGCGCTGGTG
TGGGGCGTGGCTACATCGGGCGGCCCGATCTGACCGCCGAGCGTTTTGTGCCCAATCCATTTAGTACCGAAGCTGGAGCG
CGGCTCTATCGCAGCGGCGATTTGGTGCGCTATCAGCCTGATGGCGCGATTGAATTTTTGGGTCGGATCGATCTACAAGT
CAAAATTCGTGGCTATCGGGTTGAGTTAAGCGAGATCGAAACCGCGATTCAAGCTCAGGCACAGGTTGCCAATAGTGTAG
TGATTTTGCGCGAAGACACGCCAGGTGATAAGCGCTTGGTCGCCTATATCGTGCCAGAAGCAGGCCAAAGCCTGAATATT
GGCAGCATTCGCGAGGCCTTGCGCAATAGTTTGCCCGATTATATGGTGCCAACCGCCTTTGTTGAATTAGATGGATTGCC
GTTGAACCCCAATGGCAAAATCGAACGCCGCGCCTTGCCCGCCCCCAGCAACGAGCGCAATCTCGATAGTTACGTTGCGC
CACAAACCGCCACTGAACATGAATTGGCAGGAATTTGGGCCGAGGTTTTGGGGCTTGATCAGGTTGGCATCGACGATAAT
TTCTTCGATTTAGGCGGCGAATCATTTAAAGCGATTCGGGTGGTGCGCAAAATTGGCAGCCATATCAGCGTTATGACGCT
GTTCAAATATCCGACAGTGCGTGAATTGGCCGCTCATCTCTCGGGTGCAAGCAGCGCTGAGAGCGGCGGCATGCTCTATG
AATTGAGCAAAGCACAGGCTAAACAGCACACCACGATTGTGGCAATTCCCTATGGTGGCGGCAGCGCGATCACCTATCAA
CCATTGGCCCAAGCCATGCCCAAGGGCTATCGGTTATTGGCCGCCGAGCTACCTGGCCACGATTTCAGCCGCCCCGACGA
GCCATTGCAAGCCTTAGAAGTCGTGGCGAGTCAGCTTGCCAGCGAAATTCAAACCAAAACCCAAGGGCCAATTGTGTTGT
ATGGCCATTGTGTGGGCAGCGCCATGACCGTGGAAATTGGCCGTTTGTTGGAGCAAGCAGGCCGCGACGTTCAGGGGATT
GTGCTCGGTGGCAATTTTCCGGCGGCTCGCGTGCCAGGCCGCTTCTTTGAATGGCTCAACAAACTTATGCCCGCCGATCG
TTGGATGTCGGATCGGACATATCGCGATTTTCTCCGCGCGTTGGGTGGCTTCACCGAAATTGTCGATCAAGCTGAACAAA
CCTTTGTGATGCGCAGTTTGCGCCATGATGCGCGTGAAGTTGAGCGCTATTTCACCCAAGCCTTTGCCCAAAAACAGTCG
CAACAACTCAAAGCTCCAATCGCCTGTATCATCGGCGAGATGGATCGAGCGACCGAATATTACCAAGAGCGCTACCGCGA
ATGGGAATATTTCAGCAACAATGTGACGCTGCATGTAATTCCCCACGCTGGCCATTATTTTCTCAAACATCAGGCCAGCG
AATTGGGCCAAATTATCGAGCAACAAACCGAGCAATGGCAACAACCACGGCCAATTCAGCCAACTGCCGCCAAATCAAAA
TCGCATAAAACCAGCATGCCCAGCCTACGAATTTTCTTTATGGTTGCGTTAGGCCAATTGGTTTCGATGCTTGGCTCAAG
TTTATCAAGTTTCGCCTTGGGCATTTGGATCTATCAACGAACTGGCACGGTCAGCGATTTTGCCTTTACCGCGATTGCCT
CGATGCTGCCAAGTTTGCTGGTTTCGCCATTGGCTGGAGCAATTGCCGACCGCTGGGATCGGCGCTGGATTATGATTATT
GCTGATACAATTTCGGCGCTTTCGACAATTGTGATTGCAATGTTGCTGTGGGCCAATAAACTTGAGGTTTGGCATATTTA
CCTCACGGCGGCAATTAGCTCGATTGCCGGAACCTTCCAGCGCCCAGCGTATGCCGCAGCCATGACCCAGCTTGTGCCCA
AACAATATCTGGGCCATGCCAACGGCGTGATTCAGCTTGGCTCGGCTACGGGCGGACTGATTGCACCGTTTATTGCTGGC
GGCATGGTGGCCTTCTTTGGCTTGGGCGGGGTCTTTTTGCTCGACTTCATCTCGTTCAGCTTGGGAATTGGAGTATTGTT
CTTGGTGCGCTTCCCCAACACGCTCTATCACAAGCGCGAGGAGCCATTGCTGCGCGAAATTGTGCGCGGCTGGGAATATA
TCATCAAGCGCCCAAGTTTGGTGGCGATGGTGCTGTTTTTCGCCTTGGGCAACATCTGGTTTGGCATCGCCAGTATCAGC
ATGAGTCCGTTGGTGCTTTCGTTTGGCGGGCCTGCCGAATTAGGCATTGTCAGCGCAGCTTGTGCTTTGGGCGGCTTCCT
CGGCGGCTTATTTATGAGCTTATGGGGCGGTTTGCAGCGTCGTGCCGAAGGCATGGTTGGCTTCGTCATTCTCGAAGGCT
TTTTCATTGCCTTGGCCGGGTTGCGGCCTTCGGTATGGTTGGTAGCCTTAGCGATGTTTGGAATGTGGTTTGCGATTTCG
CTGGTCAACGCCCACTGGCAAGTGCTCATTCAAACCAAAGTTGGCCTGGAGCTACAAGGGCGGGTGCAAGCAACCAACCA
AATGCTGGCCATGCTCAGCATCCCGCTGGGCTATTGGCTGGCTGGGCCATTGGCTGATAACTTGTTTGGCCCTTTGCTCG
AACCAAACGGCGCACTCAGCAGCAGTTTGGGTTGGCTCTTCGGGGTCGGGCCTGATCGCGGGATTGGCCTGTTGATGGTG
GTGGTTGGCTTAGGTGCAGCAATTTGGGCCTTGATTGGCTTCAACTATCGCCCCTTGCGCTACATGGAAGATGCCCTGCC
CGATGCCATCCCTGATGCTGAAATCGCCAGCGACCGCGATACGATTCAAGCCCAAGCCGATGGTATAATCGCTGTGACAG
CAAAAGGCTAA

Upstream 100 bases:

>100_bases
CCGACCCCAAAGTGCAACGAGCCGCTCAGTTGGCAGCCCTGCCCGCTGAACAACGAGCGCTCTTAGCTCAACGCTTGAAA
CAACGCCGAGGTGAGCAAGT

Downstream 100 bases:

>100_bases
AATCAAAAGTCAGAAGGCAAAAATCAAAAAAGCTCAGTTATAACCGCGAAGAACGCGAAGTTGCGCTAAGAGATAAAAAA
TTAAACATTCTTCGTGCGCT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1816; Mature: 1815

Protein sequence:

>1816_residues
MTEVARQLEDLSPERRALLAQRLRQRQAAKPVPSIPALARIGEHPAFELSFAQQRLWFLSQWQPESAAYHIPATFSIAGE
INVSVLQTCLDKIIQRHEVLRSTIEVLNDQPMQVIQPFRSLDLELVDLRGLSNEQQASQRQQQIERHSQQPFDLSKDLML
RGLLLHTAADHAELVLTIHHIACDGWSIGVLLRELGQLYEAGLRGEQLELPALPIQYADFAVWHKRYVLEQVYQQHLNFW
QEQLSGTLPLLNLPTDHARPAVKRDLGATVEYHLPWSLVEAVERLSRQERATPFMLFMAAFQVLLYRYSGQSDLIIGTPI
ANRTRREIENLIGFFVNTLPIRVNLAGSPSFRSLIAQVRQTSLAAFEHQDMPLEHLIDVLKVERSLSHNPLFQALFVHQT
TSIQTVDSGEFGLQFGGAIETGSAKFDINLNLAANRATFEYNTDLFERSTIERMASHFHSLLEYAVTNPDASIEHLPLLS
SSERQQLLQTWNSTSANYPAVDSIVRLFEAQAARVPERTALHFEGQTLSYAELNQRANQLAHSLRQRGIGCDMRVGLFID
RSLDLLVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAVSLLLTHAELAAELPKLDLEVLCLDQAWPTIAQAPTHNLNL
ALEPRSLMYVLFTSGSTGRPKGVAIEHHNYVNYIQGLLQRIEAEDGWSYALVSTFAADLGTTNVYGALCSGGELHIVAYE
RATDPEAFAAYFRQHRIDVMKLVPSHFEAMRGLNNLADVIPKQRLILAGEASLWEQLSDIRQLQPSVQLQNHYGPTETTV
SMLTYPIPSQPHYPSSTVPLGRPLGNVQIYVLDRRMQPTPQGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFSTEAGA
RLYRSGDLVRYQPDGAIEFLGRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNI
GSIREALRNSLPDYMVPTAFVELDGLPLNPNGKIERRALPAPSNERNLDSYVAPQTATEHELAGIWAEVLGLDQVGIDDN
FFDLGGESFKAIRVVRKIGSHISVMTLFKYPTVRELAAHLSGASSAESGGMLYELSKAQAKQHTTIVAIPYGGGSAITYQ
PLAQAMPKGYRLLAAELPGHDFSRPDEPLQALEVVASQLASEIQTKTQGPIVLYGHCVGSAMTVEIGRLLEQAGRDVQGI
VLGGNFPAARVPGRFFEWLNKLMPADRWMSDRTYRDFLRALGGFTEIVDQAEQTFVMRSLRHDAREVERYFTQAFAQKQS
QQLKAPIACIIGEMDRATEYYQERYREWEYFSNNVTLHVIPHAGHYFLKHQASELGQIIEQQTEQWQQPRPIQPTAAKSK
SHKTSMPSLRIFFMVALGQLVSMLGSSLSSFALGIWIYQRTGTVSDFAFTAIASMLPSLLVSPLAGAIADRWDRRWIMII
ADTISALSTIVIAMLLWANKLEVWHIYLTAAISSIAGTFQRPAYAAAMTQLVPKQYLGHANGVIQLGSATGGLIAPFIAG
GMVAFFGLGGVFLLDFISFSLGIGVLFLVRFPNTLYHKREEPLLREIVRGWEYIIKRPSLVAMVLFFALGNIWFGIASIS
MSPLVLSFGGPAELGIVSAACALGGFLGGLFMSLWGGLQRRAEGMVGFVILEGFFIALAGLRPSVWLVALAMFGMWFAIS
LVNAHWQVLIQTKVGLELQGRVQATNQMLAMLSIPLGYWLAGPLADNLFGPLLEPNGALSSSLGWLFGVGPDRGIGLLMV
VVGLGAAIWALIGFNYRPLRYMEDALPDAIPDAEIASDRDTIQAQADGIIAVTAKG

Sequences:

>Translated_1816_residues
MTEVARQLEDLSPERRALLAQRLRQRQAAKPVPSIPALARIGEHPAFELSFAQQRLWFLSQWQPESAAYHIPATFSIAGE
INVSVLQTCLDKIIQRHEVLRSTIEVLNDQPMQVIQPFRSLDLELVDLRGLSNEQQASQRQQQIERHSQQPFDLSKDLML
RGLLLHTAADHAELVLTIHHIACDGWSIGVLLRELGQLYEAGLRGEQLELPALPIQYADFAVWHKRYVLEQVYQQHLNFW
QEQLSGTLPLLNLPTDHARPAVKRDLGATVEYHLPWSLVEAVERLSRQERATPFMLFMAAFQVLLYRYSGQSDLIIGTPI
ANRTRREIENLIGFFVNTLPIRVNLAGSPSFRSLIAQVRQTSLAAFEHQDMPLEHLIDVLKVERSLSHNPLFQALFVHQT
TSIQTVDSGEFGLQFGGAIETGSAKFDINLNLAANRATFEYNTDLFERSTIERMASHFHSLLEYAVTNPDASIEHLPLLS
SSERQQLLQTWNSTSANYPAVDSIVRLFEAQAARVPERTALHFEGQTLSYAELNQRANQLAHSLRQRGIGCDMRVGLFID
RSLDLLVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAVSLLLTHAELAAELPKLDLEVLCLDQAWPTIAQAPTHNLNL
ALEPRSLMYVLFTSGSTGRPKGVAIEHHNYVNYIQGLLQRIEAEDGWSYALVSTFAADLGTTNVYGALCSGGELHIVAYE
RATDPEAFAAYFRQHRIDVMKLVPSHFEAMRGLNNLADVIPKQRLILAGEASLWEQLSDIRQLQPSVQLQNHYGPTETTV
SMLTYPIPSQPHYPSSTVPLGRPLGNVQIYVLDRRMQPTPQGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFSTEAGA
RLYRSGDLVRYQPDGAIEFLGRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNI
GSIREALRNSLPDYMVPTAFVELDGLPLNPNGKIERRALPAPSNERNLDSYVAPQTATEHELAGIWAEVLGLDQVGIDDN
FFDLGGESFKAIRVVRKIGSHISVMTLFKYPTVRELAAHLSGASSAESGGMLYELSKAQAKQHTTIVAIPYGGGSAITYQ
PLAQAMPKGYRLLAAELPGHDFSRPDEPLQALEVVASQLASEIQTKTQGPIVLYGHCVGSAMTVEIGRLLEQAGRDVQGI
VLGGNFPAARVPGRFFEWLNKLMPADRWMSDRTYRDFLRALGGFTEIVDQAEQTFVMRSLRHDAREVERYFTQAFAQKQS
QQLKAPIACIIGEMDRATEYYQERYREWEYFSNNVTLHVIPHAGHYFLKHQASELGQIIEQQTEQWQQPRPIQPTAAKSK
SHKTSMPSLRIFFMVALGQLVSMLGSSLSSFALGIWIYQRTGTVSDFAFTAIASMLPSLLVSPLAGAIADRWDRRWIMII
ADTISALSTIVIAMLLWANKLEVWHIYLTAAISSIAGTFQRPAYAAAMTQLVPKQYLGHANGVIQLGSATGGLIAPFIAG
GMVAFFGLGGVFLLDFISFSLGIGVLFLVRFPNTLYHKREEPLLREIVRGWEYIIKRPSLVAMVLFFALGNIWFGIASIS
MSPLVLSFGGPAELGIVSAACALGGFLGGLFMSLWGGLQRRAEGMVGFVILEGFFIALAGLRPSVWLVALAMFGMWFAIS
LVNAHWQVLIQTKVGLELQGRVQATNQMLAMLSIPLGYWLAGPLADNLFGPLLEPNGALSSSLGWLFGVGPDRGIGLLMV
VVGLGAAIWALIGFNYRPLRYMEDALPDAIPDAEIASDRDTIQAQADGIIAVTAKG
>Mature_1815_residues
TEVARQLEDLSPERRALLAQRLRQRQAAKPVPSIPALARIGEHPAFELSFAQQRLWFLSQWQPESAAYHIPATFSIAGEI
NVSVLQTCLDKIIQRHEVLRSTIEVLNDQPMQVIQPFRSLDLELVDLRGLSNEQQASQRQQQIERHSQQPFDLSKDLMLR
GLLLHTAADHAELVLTIHHIACDGWSIGVLLRELGQLYEAGLRGEQLELPALPIQYADFAVWHKRYVLEQVYQQHLNFWQ
EQLSGTLPLLNLPTDHARPAVKRDLGATVEYHLPWSLVEAVERLSRQERATPFMLFMAAFQVLLYRYSGQSDLIIGTPIA
NRTRREIENLIGFFVNTLPIRVNLAGSPSFRSLIAQVRQTSLAAFEHQDMPLEHLIDVLKVERSLSHNPLFQALFVHQTT
SIQTVDSGEFGLQFGGAIETGSAKFDINLNLAANRATFEYNTDLFERSTIERMASHFHSLLEYAVTNPDASIEHLPLLSS
SERQQLLQTWNSTSANYPAVDSIVRLFEAQAARVPERTALHFEGQTLSYAELNQRANQLAHSLRQRGIGCDMRVGLFIDR
SLDLLVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAVSLLLTHAELAAELPKLDLEVLCLDQAWPTIAQAPTHNLNLA
LEPRSLMYVLFTSGSTGRPKGVAIEHHNYVNYIQGLLQRIEAEDGWSYALVSTFAADLGTTNVYGALCSGGELHIVAYER
ATDPEAFAAYFRQHRIDVMKLVPSHFEAMRGLNNLADVIPKQRLILAGEASLWEQLSDIRQLQPSVQLQNHYGPTETTVS
MLTYPIPSQPHYPSSTVPLGRPLGNVQIYVLDRRMQPTPQGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFSTEAGAR
LYRSGDLVRYQPDGAIEFLGRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNIG
SIREALRNSLPDYMVPTAFVELDGLPLNPNGKIERRALPAPSNERNLDSYVAPQTATEHELAGIWAEVLGLDQVGIDDNF
FDLGGESFKAIRVVRKIGSHISVMTLFKYPTVRELAAHLSGASSAESGGMLYELSKAQAKQHTTIVAIPYGGGSAITYQP
LAQAMPKGYRLLAAELPGHDFSRPDEPLQALEVVASQLASEIQTKTQGPIVLYGHCVGSAMTVEIGRLLEQAGRDVQGIV
LGGNFPAARVPGRFFEWLNKLMPADRWMSDRTYRDFLRALGGFTEIVDQAEQTFVMRSLRHDAREVERYFTQAFAQKQSQ
QLKAPIACIIGEMDRATEYYQERYREWEYFSNNVTLHVIPHAGHYFLKHQASELGQIIEQQTEQWQQPRPIQPTAAKSKS
HKTSMPSLRIFFMVALGQLVSMLGSSLSSFALGIWIYQRTGTVSDFAFTAIASMLPSLLVSPLAGAIADRWDRRWIMIIA
DTISALSTIVIAMLLWANKLEVWHIYLTAAISSIAGTFQRPAYAAAMTQLVPKQYLGHANGVIQLGSATGGLIAPFIAGG
MVAFFGLGGVFLLDFISFSLGIGVLFLVRFPNTLYHKREEPLLREIVRGWEYIIKRPSLVAMVLFFALGNIWFGIASISM
SPLVLSFGGPAELGIVSAACALGGFLGGLFMSLWGGLQRRAEGMVGFVILEGFFIALAGLRPSVWLVALAMFGMWFAISL
VNAHWQVLIQTKVGLELQGRVQATNQMLAMLSIPLGYWLAGPLADNLFGPLLEPNGALSSSLGWLFGVGPDRGIGLLMVV
VGLGAAIWALIGFNYRPLRYMEDALPDAIPDAEIASDRDTIQAQADGIIAVTAKG

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=543, Percent_Identity=24.4935543278085, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI187761343, Length=543, Percent_Identity=24.4935543278085, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI157311624, Length=533, Percent_Identity=23.0769230769231, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI157311622, Length=533, Percent_Identity=23.0769230769231, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI58082049, Length=537, Percent_Identity=22.7188081936685, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI38505220, Length=503, Percent_Identity=22.2664015904573, Blast_Score=74, Evalue=1e-12,
Organism=Escherichia coli, GI1786801, Length=1204, Percent_Identity=26.9102990033223, Blast_Score=335, Evalue=1e-92,
Organism=Escherichia coli, GI221142682, Length=494, Percent_Identity=24.8987854251012, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786810, Length=499, Percent_Identity=23.6472945891784, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI145693145, Length=527, Percent_Identity=24.0986717267552, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1790505, Length=550, Percent_Identity=22.9090909090909, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=1084, Percent_Identity=22.2324723247232, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17556356, Length=619, Percent_Identity=24.232633279483, Blast_Score=139, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17558820, Length=505, Percent_Identity=25.7425742574257, Blast_Score=95, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32563687, Length=523, Percent_Identity=23.5181644359465, Blast_Score=81, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=966, Percent_Identity=25.776397515528, Blast_Score=250, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6319699, Length=358, Percent_Identity=22.3463687150838, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648676, Length=679, Percent_Identity=27.2459499263623, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24581924, Length=526, Percent_Identity=24.3346007604563, Blast_Score=94, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582852, Length=452, Percent_Identity=25.4424778761062, Blast_Score=86, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355181, Length=520, Percent_Identity=21.3461538461538, Blast_Score=74, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 200886; Mature: 200755

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVARQLEDLSPERRALLAQRLRQRQAAKPVPSIPALARIGEHPAFELSFAQQRLWFLS
CCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHH
QWQPESAAYHIPATFSIAGEINVSVLQTCLDKIIQRHEVLRSTIEVLNDQPMQVIQPFRS
CCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDLELVDLRGLSNEQQASQRQQQIERHSQQPFDLSKDLMLRGLLLHTAADHAELVLTIHH
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHEEEEEEE
IACDGWSIGVLLRELGQLYEAGLRGEQLELPALPIQYADFAVWHKRYVLEQVYQQHLNFW
HHCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEQLSGTLPLLNLPTDHARPAVKRDLGATVEYHLPWSLVEAVERLSRQERATPFMLFMAA
HHHHCCCCCEEECCCCCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHH
FQVLLYRYSGQSDLIIGTPIANRTRREIENLIGFFVNTLPIRVNLAGSPSFRSLIAQVRQ
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHH
TSLAAFEHQDMPLEHLIDVLKVERSLSHNPLFQALFVHQTTSIQTVDSGEFGLQFGGAIE
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCEEECCEEE
TGSAKFDINLNLAANRATFEYNTDLFERSTIERMASHFHSLLEYAVTNPDASIEHLPLLS
CCCEEEEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SSERQQLLQTWNSTSANYPAVDSIVRLFEAQAARVPERTALHFEGQTLSYAELNQRANQL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
AHSLRQRGIGCDMRVGLFIDRSLDLLVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAV
HHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCC
SLLLTHAELAAELPKLDLEVLCLDQAWPTIAQAPTHNLNLALEPRSLMYVLFTSGSTGRP
EEEHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCCCCCEEEECCCEEEEEEEECCCCCCC
KGVAIEHHNYVNYIQGLLQRIEAEDGWSYALVSTFAADLGTTNVYGALCSGGELHIVAYE
CCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEE
RATDPEAFAAYFRQHRIDVMKLVPSHFEAMRGLNNLADVIPKQRLILAGEASLWEQLSDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
RQLQPSVQLQNHYGPTETTVSMLTYPIPSQPHYPSSTVPLGRPLGNVQIYVLDRRMQPTP
HHHCCCHHHHCCCCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
QGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFSTEAGARLYRSGDLVRYQPDGAIEFL
CCCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHH
GRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNI
HEEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCCH
GSIREALRNSLPDYMVPTAFVELDGLPLNPNGKIERRALPAPSNERNLDSYVAPQTATEH
HHHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHH
ELAGIWAEVLGLDQVGIDDNFFDLGGESFKAIRVVRKIGSHISVMTLFKYPTVRELAAHL
HHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHH
SGASSAESGGMLYELSKAQAKQHTTIVAIPYGGGSAITYQPLAQAMPKGYRLLAAELPGH
CCCCCCCCCCEEEEEHHHHHHCCCEEEEEECCCCCCEEECHHHHHCCCCEEEEEEECCCC
DFSRPDEPLQALEVVASQLASEIQTKTQGPIVLYGHCVGSAMTVEIGRLLEQAGRDVQGI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEE
VLGGNFPAARVPGRFFEWLNKLMPADRWMSDRTYRDFLRALGGFTEIVDQAEQTFVMRSL
EEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RHDAREVERYFTQAFAQKQSQQLKAPIACIIGEMDRATEYYQERYREWEYFSNNVTLHVI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
PHAGHYFLKHQASELGQIIEQQTEQWQQPRPIQPTAAKSKSHKTSMPSLRIFFMVALGQL
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VSMLGSSLSSFALGIWIYQRTGTVSDFAFTAIASMLPSLLVSPLAGAIADRWDRRWIMII
HHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ADTISALSTIVIAMLLWANKLEVWHIYLTAAISSIAGTFQRPAYAAAMTQLVPKQYLGHA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
NGVIQLGSATGGLIAPFIAGGMVAFFGLGGVFLLDFISFSLGIGVLFLVRFPNTLYHKRE
CCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
EPLLREIVRGWEYIIKRPSLVAMVLFFALGNIWFGIASISMSPLVLSFGGPAELGIVSAA
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
CALGGFLGGLFMSLWGGLQRRAEGMVGFVILEGFFIALAGLRPSVWLVALAMFGMWFAIS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVNAHWQVLIQTKVGLELQGRVQATNQMLAMLSIPLGYWLAGPLADNLFGPLLEPNGALS
HHHCCEEEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
SSLGWLFGVGPDRGIGLLMVVVGLGAAIWALIGFNYRPLRYMEDALPDAIPDAEIASDRD
HCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHCCCCH
TIQAQADGIIAVTAKG
HHHHCCCCEEEEEECC
>Mature Secondary Structure 
TEVARQLEDLSPERRALLAQRLRQRQAAKPVPSIPALARIGEHPAFELSFAQQRLWFLS
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHH
QWQPESAAYHIPATFSIAGEINVSVLQTCLDKIIQRHEVLRSTIEVLNDQPMQVIQPFRS
CCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDLELVDLRGLSNEQQASQRQQQIERHSQQPFDLSKDLMLRGLLLHTAADHAELVLTIHH
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHEEEEEEE
IACDGWSIGVLLRELGQLYEAGLRGEQLELPALPIQYADFAVWHKRYVLEQVYQQHLNFW
HHCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEQLSGTLPLLNLPTDHARPAVKRDLGATVEYHLPWSLVEAVERLSRQERATPFMLFMAA
HHHHCCCCCEEECCCCCCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHH
FQVLLYRYSGQSDLIIGTPIANRTRREIENLIGFFVNTLPIRVNLAGSPSFRSLIAQVRQ
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHH
TSLAAFEHQDMPLEHLIDVLKVERSLSHNPLFQALFVHQTTSIQTVDSGEFGLQFGGAIE
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCEEECCEEE
TGSAKFDINLNLAANRATFEYNTDLFERSTIERMASHFHSLLEYAVTNPDASIEHLPLLS
CCCEEEEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SSERQQLLQTWNSTSANYPAVDSIVRLFEAQAARVPERTALHFEGQTLSYAELNQRANQL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
AHSLRQRGIGCDMRVGLFIDRSLDLLVGALGILKAGAAYVPIDPIYPQDRISAMLEDGAV
HHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCC
SLLLTHAELAAELPKLDLEVLCLDQAWPTIAQAPTHNLNLALEPRSLMYVLFTSGSTGRP
EEEHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCCCCCEEEECCCEEEEEEEECCCCCCC
KGVAIEHHNYVNYIQGLLQRIEAEDGWSYALVSTFAADLGTTNVYGALCSGGELHIVAYE
CCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEE
RATDPEAFAAYFRQHRIDVMKLVPSHFEAMRGLNNLADVIPKQRLILAGEASLWEQLSDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
RQLQPSVQLQNHYGPTETTVSMLTYPIPSQPHYPSSTVPLGRPLGNVQIYVLDRRMQPTP
HHHCCCHHHHCCCCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
QGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFSTEAGARLYRSGDLVRYQPDGAIEFL
CCCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHH
GRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVILREDTPGDKRLVAYIVPEAGQSLNI
HEEEEEEEEEEEEEEHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCCH
GSIREALRNSLPDYMVPTAFVELDGLPLNPNGKIERRALPAPSNERNLDSYVAPQTATEH
HHHHHHHHHCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHH
ELAGIWAEVLGLDQVGIDDNFFDLGGESFKAIRVVRKIGSHISVMTLFKYPTVRELAAHL
HHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHH
SGASSAESGGMLYELSKAQAKQHTTIVAIPYGGGSAITYQPLAQAMPKGYRLLAAELPGH
CCCCCCCCCCEEEEEHHHHHHCCCEEEEEECCCCCCEEECHHHHHCCCCEEEEEEECCCC
DFSRPDEPLQALEVVASQLASEIQTKTQGPIVLYGHCVGSAMTVEIGRLLEQAGRDVQGI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEE
VLGGNFPAARVPGRFFEWLNKLMPADRWMSDRTYRDFLRALGGFTEIVDQAEQTFVMRSL
EEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RHDAREVERYFTQAFAQKQSQQLKAPIACIIGEMDRATEYYQERYREWEYFSNNVTLHVI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
PHAGHYFLKHQASELGQIIEQQTEQWQQPRPIQPTAAKSKSHKTSMPSLRIFFMVALGQL
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VSMLGSSLSSFALGIWIYQRTGTVSDFAFTAIASMLPSLLVSPLAGAIADRWDRRWIMII
HHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ADTISALSTIVIAMLLWANKLEVWHIYLTAAISSIAGTFQRPAYAAAMTQLVPKQYLGHA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
NGVIQLGSATGGLIAPFIAGGMVAFFGLGGVFLLDFISFSLGIGVLFLVRFPNTLYHKRE
CCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
EPLLREIVRGWEYIIKRPSLVAMVLFFALGNIWFGIASISMSPLVLSFGGPAELGIVSAA
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
CALGGFLGGLFMSLWGGLQRRAEGMVGFVILEGFFIALAGLRPSVWLVALAMFGMWFAIS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVNAHWQVLIQTKVGLELQGRVQATNQMLAMLSIPLGYWLAGPLADNLFGPLLEPNGALS
HHHCCEEEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
SSLGWLFGVGPDRGIGLLMVVVGLGAAIWALIGFNYRPLRYMEDALPDAIPDAEIASDRD
HCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHCCCCH
TIQAQADGIIAVTAKG
HHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA