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The map label for this gene is nuoC

Identifier: 159899600

GI number: 159899600

Start: 3890471

End: 3890986

Strand: Direct

Name: nuoC

Synonym: Haur_3081

Alternate gene names: 159899600

Gene position: 3890471-3890986 (Clockwise)

Preceding gene: 159899599

Following gene: 159899601

Centisome position: 61.3

GC content: 50.0

Gene sequence:

>516_bases
ATGATTGATAGAGCAACCTTGGAGCAGCGCGTTTCTGCCCAATTCCCTACCGTTCGCATTGGCGATGAATCCGGCGATTT
GTGCTTGACCGTCGAACGCCAACAATTGCCTGCACTGGCTGGTTGGCTGCGCGATGAGCCAGATCTCGCGTTTACCTTTT
TAAATCAATTATGTGGGGTCGATTACCTGGGGCGTGATCCACGCTTTGAGGTGGTTGTTCATTTGACCTCATTTCAAAAT
AAAATGCGGGTAACGTTGCATATCGAAGTACCCGAAGCTGATCCAACGATTCCAACCTTGGCTCGGCTCTTTCCAACTGC
CAACTTCCAAGAGCGCGAAACCTACGATATGTTTGGCATTATCTTCACCGGGCATCCTGGCTTGGAACGTATTTTGATGC
CCGAAGATTGGTTAGGTCATCCCCAGCGCAAGGATCATCCCTTGGGCTATGAGGAAGTGGCCTTCACCCACAACGAAGAT
TGGATTTACGCCAATAAGCCCTTCGCGAAGGAGTAA

Upstream 100 bases:

>100_bases
CTAAGGCATTGCCCTACGTTGTATTTGGTGCCACCATTACGCTGGCAACGCCCTGTTGCAGCGTCTCGCCGTGGCTGCGT
CACTCTTCATTGAGGAAGCT

Downstream 100 bases:

>100_bases
TGCGCTATGGTGATGCACGCACATGCGTATCCCGATATTGAAATTCCAACACCTTCGCAAATTGCGGCGGTGGCATTAAA
TAACGAGCCTGATGAAAACG

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGVDYLGRDPRFEVVVHLTSFQN
KMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGIIFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNED
WIYANKPFAKE

Sequences:

>Translated_171_residues
MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGVDYLGRDPRFEVVVHLTSFQN
KMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGIIFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNED
WIYANKPFAKE
>Mature_171_residues
MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGVDYLGRDPRFEVVVHLTSFQN
KMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGIIFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNED
WIYANKPFAKE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=121, Percent_Identity=40.495867768595, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI145693162, Length=131, Percent_Identity=39.6946564885496, Blast_Score=97, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=121, Percent_Identity=38.8429752066116, Blast_Score=76, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32563621, Length=136, Percent_Identity=36.7647058823529, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656494, Length=115, Percent_Identity=39.1304347826087, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_HERA2 (A9B4Z6)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545847.1
- ProteinModelPortal:   A9B4Z6
- SMR:   A9B4Z6
- GeneID:   5734953
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3081
- HOGENOM:   HBG727675
- OMA:   KFNYMAC
- ProtClustDB:   CLSK974897
- BioCyc:   HAUR316274:HAUR_3081-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 19726; Mature: 19726

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGV
CCCHHHHHHHHHCCCCEEEECCCCCCEEEEECHHHCHHHHHHHCCCCCHHHHHHHHHHCC
DYLGRDPRFEVVVHLTSFQNKMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGI
CCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEE
IFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNEDWIYANKPFAKE
EEECCCCCCEEECCHHHCCCCCCCCCCCCHHHEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGV
CCCHHHHHHHHHCCCCEEEECCCCCCEEEEECHHHCHHHHHHHCCCCCHHHHHHHHHHCC
DYLGRDPRFEVVVHLTSFQNKMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGI
CCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEE
IFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNEDWIYANKPFAKE
EEECCCCCCEEECCHHHCCCCCCCCCCCCHHHEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA