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The map label for this gene is nuoD1

Identifier: 159899601

GI number: 159899601

Start: 3890993

End: 3892261

Strand: Direct

Name: nuoD1

Synonym: Haur_3082

Alternate gene names: 159899601

Gene position: 3890993-3892261 (Clockwise)

Preceding gene: 159899600

Following gene: 159899602

Centisome position: 61.31

GC content: 52.17

Gene sequence:

>1269_bases
ATGGTGATGCACGCACATGCGTATCCCGATATTGAAATTCCAACACCTTCGCAAATTGCGGCGGTGGCATTAAATAACGA
GCCTGATGAAAACGGCGAGCAATCCATGGTGCTCAGCATGGGGCCACAACACCCTTCAACGCACGGGGTGCTACGGCTAG
CCGTCGAACTCAATGGCGAAAACGTGGTGCAACTGGCTCCCGACGTGGGCTTTTTGCACACCGGCATCGAAAAAACCATC
GAAACCAAAACCTACACCAAATCAATTGTGCTGACCGACCGCATGGATTACCTTGCGCCGATGTCGAACAATATGGTGTA
TGTGGCGGCGATTGAAAAATTGATGCAGCAAGATGTGCCAGAACGCGCCCAAACCTTGCGGGTGTTGTTGCTGGAACTGA
CGCGGATCAACTCGCACTTGGTTTGGTTGGGCACGCACGCGCTCGACTTGGCCGCGATGAGTGTGTTTTTTTATGCAATG
CGTGAACGTGAGTATATTCTCGATATTTTCGAGATGCTGACTGGCGCACGTATGATGACCAGCTATTTCCGCGTTGGTGG
TTTGGCATGGGATATTCCAGCCGACTTTATTCCAACTGTGGAAGATTTCTTGACCCACTTTTTGCCCAAGGTCGATGAAT
ATGAAGATTTGTTGACCAATAACTTGTTGTGGAAACAACGCACCAAGGGCGTAGGCGTGGTCAATGCTGCTGATGCAATT
GCCCTCGGCTTGTCGGGCGCGAACCTACGGGCCAGCGGTGTCGATTGGGATTTGCGCAAAACCATGCCCTACAGCGGCTA
CGAAACCTACCAATTCGATGTACCAGTCGGCCAAGCTGGCGATATTTACGATCGCTATCGCTGTCGGGTGCAAGAAATGC
GCGAAAGCGTCAAGATTGCCCGTCAAGCGATCGAACGCGTCAAGCAAATGCATGGCCAGCCCTATGTGACCGAAAATCGT
AAGGTTGCGCCACCACCCAAGAGCGAAATTACCTACAGCATGGAATCGCTCATTCACCACTTTAAGCTGTGGACGGAAGG
CTTCCGCCCACCGCGTGGTTCGGCCTATGCGGCAATCGAATCACCACGAGGTGAAATTGGCTGTTATGTGGTGAGCGATG
GCACTCCCAAACCATGGCGTGTCCACTTCCGCGCACCGTCATTTATTAATTTGCAAGCCTTGCCCCACATCGCCAAAGGC
AAATTGATGGCCGACTTGGTGGCATTGATTGCGAGCATCGATCCGGTGCTTGGTGAAGTGGATCGTTAA

Upstream 100 bases:

>100_bases
CCAGCGCAAGGATCATCCCTTGGGCTATGAGGAAGTGGCCTTCACCCACAACGAAGATTGGATTTACGCCAATAAGCCCT
TCGCGAAGGAGTAATGCGCT

Downstream 100 bases:

>100_bases
GAAGGAGCTTAGGGTGCTGTACGAACAACACAAGGCTGAAATTGATGAAATTTTGGCCCGCTATCCTGTAGATCGCAAAC
GCTCGGCCTTGTTGCCGTTG

Product: NADH dehydrogenase I subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D 1; NDH-1 subunit D 1

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MVMHAHAYPDIEIPTPSQIAAVALNNEPDENGEQSMVLSMGPQHPSTHGVLRLAVELNGENVVQLAPDVGFLHTGIEKTI
ETKTYTKSIVLTDRMDYLAPMSNNMVYVAAIEKLMQQDVPERAQTLRVLLLELTRINSHLVWLGTHALDLAAMSVFFYAM
REREYILDIFEMLTGARMMTSYFRVGGLAWDIPADFIPTVEDFLTHFLPKVDEYEDLLTNNLLWKQRTKGVGVVNAADAI
ALGLSGANLRASGVDWDLRKTMPYSGYETYQFDVPVGQAGDIYDRYRCRVQEMRESVKIARQAIERVKQMHGQPYVTENR
KVAPPPKSEITYSMESLIHHFKLWTEGFRPPRGSAYAAIESPRGEIGCYVVSDGTPKPWRVHFRAPSFINLQALPHIAKG
KLMADLVALIASIDPVLGEVDR

Sequences:

>Translated_422_residues
MVMHAHAYPDIEIPTPSQIAAVALNNEPDENGEQSMVLSMGPQHPSTHGVLRLAVELNGENVVQLAPDVGFLHTGIEKTI
ETKTYTKSIVLTDRMDYLAPMSNNMVYVAAIEKLMQQDVPERAQTLRVLLLELTRINSHLVWLGTHALDLAAMSVFFYAM
REREYILDIFEMLTGARMMTSYFRVGGLAWDIPADFIPTVEDFLTHFLPKVDEYEDLLTNNLLWKQRTKGVGVVNAADAI
ALGLSGANLRASGVDWDLRKTMPYSGYETYQFDVPVGQAGDIYDRYRCRVQEMRESVKIARQAIERVKQMHGQPYVTENR
KVAPPPKSEITYSMESLIHHFKLWTEGFRPPRGSAYAAIESPRGEIGCYVVSDGTPKPWRVHFRAPSFINLQALPHIAKG
KLMADLVALIASIDPVLGEVDR
>Mature_422_residues
MVMHAHAYPDIEIPTPSQIAAVALNNEPDENGEQSMVLSMGPQHPSTHGVLRLAVELNGENVVQLAPDVGFLHTGIEKTI
ETKTYTKSIVLTDRMDYLAPMSNNMVYVAAIEKLMQQDVPERAQTLRVLLLELTRINSHLVWLGTHALDLAAMSVFFYAM
REREYILDIFEMLTGARMMTSYFRVGGLAWDIPADFIPTVEDFLTHFLPKVDEYEDLLTNNLLWKQRTKGVGVVNAADAI
ALGLSGANLRASGVDWDLRKTMPYSGYETYQFDVPVGQAGDIYDRYRCRVQEMRESVKIARQAIERVKQMHGQPYVTENR
KVAPPPKSEITYSMESLIHHFKLWTEGFRPPRGSAYAAIESPRGEIGCYVVSDGTPKPWRVHFRAPSFINLQALPHIAKG
KLMADLVALIASIDPVLGEVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=397, Percent_Identity=47.103274559194, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI260898743, Length=387, Percent_Identity=46.5116279069767, Blast_Score=365, Evalue=1e-101,
Organism=Escherichia coli, GI145693162, Length=408, Percent_Identity=38.4803921568627, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1789076, Length=393, Percent_Identity=27.4809160305344, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788832, Length=397, Percent_Identity=25.9445843828715, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17555284, Length=393, Percent_Identity=46.8193384223919, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17568379, Length=393, Percent_Identity=46.3104325699746, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24638644, Length=395, Percent_Identity=47.3417721518987, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI221459469, Length=389, Percent_Identity=42.6735218508997, Blast_Score=360, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD1_HERA2 (A9B4Z7)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545848.1
- ProteinModelPortal:   A9B4Z7
- SMR:   A9B4Z7
- GeneID:   5734954
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3082
- HOGENOM:   HBG459705
- OMA:   MFANEGY
- ProtClustDB:   CLSK974896
- BioCyc:   HAUR316274:HAUR_3082-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 47415; Mature: 47415

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMHAHAYPDIEIPTPSQIAAVALNNEPDENGEQSMVLSMGPQHPSTHGVLRLAVELNGE
CEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCC
NVVQLAPDVGFLHTGIEKTIETKTYTKSIVLTDRMDYLAPMSNNMVYVAAIEKLMQQDVP
CEEEECCCCCHHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCCCEEEHHHHHHHHHHCCH
ERAQTLRVLLLELTRINSHLVWLGTHALDLAAMSVFFYAMREREYILDIFEMLTGARMMT
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYFRVGGLAWDIPADFIPTVEDFLTHFLPKVDEYEDLLTNNLLWKQRTKGVGVVNAADAI
HHHHHCCEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCEEECCHHH
ALGLSGANLRASGVDWDLRKTMPYSGYETYQFDVPVGQAGDIYDRYRCRVQEMRESVKIA
EEECCCCCEEECCCCCHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
RQAIERVKQMHGQPYVTENRKVAPPPKSEITYSMESLIHHFKLWTEGFRPPRGSAYAAIE
HHHHHHHHHHCCCCEECCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
SPRGEIGCYVVSDGTPKPWRVHFRAPSFINLQALPHIAKGKLMADLVALIASIDPVLGEV
CCCCCEEEEEEECCCCCCEEEEEECCCEEEHHHCCCHHHHHHHHHHHHHHHHHCHHHHCC
DR
CC
>Mature Secondary Structure
MVMHAHAYPDIEIPTPSQIAAVALNNEPDENGEQSMVLSMGPQHPSTHGVLRLAVELNGE
CEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCC
NVVQLAPDVGFLHTGIEKTIETKTYTKSIVLTDRMDYLAPMSNNMVYVAAIEKLMQQDVP
CEEEECCCCCHHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCCCEEEHHHHHHHHHHCCH
ERAQTLRVLLLELTRINSHLVWLGTHALDLAAMSVFFYAMREREYILDIFEMLTGARMMT
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYFRVGGLAWDIPADFIPTVEDFLTHFLPKVDEYEDLLTNNLLWKQRTKGVGVVNAADAI
HHHHHCCEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCEEECCHHH
ALGLSGANLRASGVDWDLRKTMPYSGYETYQFDVPVGQAGDIYDRYRCRVQEMRESVKIA
EEECCCCCEEECCCCCHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
RQAIERVKQMHGQPYVTENRKVAPPPKSEITYSMESLIHHFKLWTEGFRPPRGSAYAAIE
HHHHHHHHHHCCCCEECCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
SPRGEIGCYVVSDGTPKPWRVHFRAPSFINLQALPHIAKGKLMADLVALIASIDPVLGEV
CCCCCEEEEEEECCCCCCEEEEEECCCEEEHHHCCCHHHHHHHHHHHHHHHHHCHHHHCC
DR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA