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The map label for this gene is nuoB1

Identifier: 159899599

GI number: 159899599

Start: 3889779

End: 3890318

Strand: Direct

Name: nuoB1

Synonym: Haur_3080

Alternate gene names: 159899599

Gene position: 3889779-3890318 (Clockwise)

Preceding gene: 159899598

Following gene: 159899600

Centisome position: 61.29

GC content: 54.81

Gene sequence:

>540_bases
ATGGGATTAGAAGAAAAAGCTGGCGATTTGGGGATTGTTACGACAACCCTCGAAGGTGTCGTCAACTGGGGTCGCACCAA
GGCGATGTGGCCGATGTTGTTTGGGTTGGCTTGCTGTGCCATCGAAATGATGGCCGGTCAAGCCTCAAATTACGATATGT
CACGCTTTGGGCTGGAGTTGATGCGGGCCTCACCGCGCCAAGCCGATTTGATGATTGTGGCTGGGCGGGTCAGCCGTAAG
ATGGCTCCAGTGTTACGCCGCCTCTACGACCAAATGCCCGAACCCAAGTGGGTTGTGGCCATGGGCGATTGTGCCTCGTG
TGGTGGGGTCTACAACAACTATGCGATCGTGCAAGGTGTTGATGAAATTGTGCCAGTTGATGTCTATGTGGCTGGCTGCC
CACCCCGCCCCGAAGCCTTGATCGACGGGATTTTGCAATTGCACGAGAAGATCAAGCGCGACAAAATCACCGATCACGCC
GATGGCAAGCCGATTCGGATCGAACAAGCAGAACGTGGCGCACTTAAGCCACTTGGCTAA

Upstream 100 bases:

>100_bases
ATTTCCGCCAAATGGGCCTATTTGGGCTAGCCGAAATGGGCGCATTTATGGGCATTCTGCTAGTTGGCTTTGTCTACATC
TGGCGGAAAGGGGCGCTCCG

Downstream 100 bases:

>100_bases
ATGTCGCCAATCTGTCGTGGGGCAATGGGCCTTGATCACCGGCGATCAAGCGCTAAGGCATTGCCCTACGTTGTATTTGG
TGCCACCATTACGCTGGCAA

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B 1; NDH-1 subunit B 1

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MGLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLELMRASPRQADLMIVAGRVSRK
MAPVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGVDEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHA
DGKPIRIEQAERGALKPLG

Sequences:

>Translated_179_residues
MGLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLELMRASPRQADLMIVAGRVSRK
MAPVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGVDEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHA
DGKPIRIEQAERGALKPLG
>Mature_178_residues
GLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLELMRASPRQADLMIVAGRVSRKM
APVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGVDEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHAD
GKPIRIEQAERGALKPLG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family

Homologues:

Organism=Homo sapiens, GI187281616, Length=144, Percent_Identity=59.7222222222222, Blast_Score=188, Evalue=3e-48,
Organism=Escherichia coli, GI1788624, Length=151, Percent_Identity=52.317880794702, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1789074, Length=111, Percent_Identity=38.7387387387387, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788834, Length=111, Percent_Identity=38.7387387387387, Blast_Score=87, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17509685, Length=140, Percent_Identity=57.1428571428571, Blast_Score=176, Evalue=4e-45,
Organism=Drosophila melanogaster, GI18859983, Length=140, Percent_Identity=58.5714285714286, Blast_Score=184, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24642371, Length=140, Percent_Identity=58.5714285714286, Blast_Score=184, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24651058, Length=138, Percent_Identity=59.4202898550725, Blast_Score=182, Evalue=1e-46,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOB1_HERA2 (A9B4Z5)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545846.1
- ProteinModelPortal:   A9B4Z5
- SMR:   A9B4Z5
- GeneID:   5734952
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3080
- HOGENOM:   HBG553221
- OMA:   SALWPET
- ProtClustDB:   PRK06411
- BioCyc:   HAUR316274:HAUR_3080-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01356
- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406
- PANTHER:   PTHR11995:SF2
- PANTHER:   PTHR11995
- TIGRFAMs:   TIGR01957

Pfam domain/function: PF01058 Oxidored_q6

EC number: =1.6.99.5

Molecular weight: Translated: 19604; Mature: 19473

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLEL
CCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
MRASPRQADLMIVAGRVSRKMAPVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGV
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCCCCCHHHCCCC
DEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHADGKPIRIEQAERGALKPLG
CHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLEL
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
MRASPRQADLMIVAGRVSRKMAPVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGV
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCCCCCHHHCCCC
DEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHADGKPIRIEQAERGALKPLG
CHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA