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The map label for this gene is yusZ [H]

Identifier: 159899452

GI number: 159899452

Start: 3708647

End: 3709540

Strand: Direct

Name: yusZ [H]

Synonym: Haur_2933

Alternate gene names: 159899452

Gene position: 3708647-3709540 (Clockwise)

Preceding gene: 159899450

Following gene: 159899454

Centisome position: 58.44

GC content: 50.34

Gene sequence:

>894_bases
ATGGCACACGCTCAAACAATTTTGGTAACTGGGAGCAGCAGCGGTTTGGGTCGGGCAATCGTCGAAACTTTGGCCCAGCA
TGGCCACACCGTATTCGCCTCAATGCGCGGGATTGCTGGCAAAAATGCCCAGGCCGCCCAAGAATTACGCGATTTTGCTA
GCCAACATGGATTAAACATCGAGCCAATCGAGCTTGATGTAGTCAATCAAGCCTCAGTCGATCAGGCAATTGCCACAATT
CAAGCCAAAGCAGGCCGCCTCGATTGTTTGATCAACAACGCGGGCGCTGGCTTGGCGGGCTTAACCGAGGCTTGTAGCAT
CGAGCAAGTTCAGCAATTATTTGATATCAATGTGTTTGGGGCATTGCGGGTTAGCAAAGCTGTTTTGCCATTAATGCGCC
AACAGCAAGCAGGCCTGTTGATCACGATCTCCAGTACCAGTACCCAAATCGTTGTGCCATTTTTGGCCGCCTATGGAGCC
AGCAAAGCTGCTGAAGAAATTATGGCCCAAAGCATGTTTTACGAATTGACCTCGCTGGGGATTGATAGCGTAATTTTGCA
ACTAGGTGGCTATGCAACCAAGTTTGGCACGAATATTCAGGTTGCCGCCGACCAAAGCCTGAATGCCGCCTATGGCTTGG
CTGGTCAATTTGCCCAAGGCATCAGCACAGGCATTGTGGCTGGGCTTGAGTATGCTGATAATCCAGTTGACGTTGGCAAT
AAAATCAACGAAATTTTGGCAATGCCCAGCGAGCAACGCCCACGCAAATATAGCATGGGCGGTGGTTCACAAGGCCTGAA
TGAACTCAACCAACAGCTTGAGCCATTGCAAGCAGGTTTGATCAGCTTGATGCAGATGGAACCATTGTTGTTGCGCAGCC
AAACTGCCAGCTAG

Upstream 100 bases:

>100_bases
AAGCCCAATTAAGTGTCAGATTTTTGGGCCTGCTGGCCCTCTCTACTACGGCAGATAATTAAGCTATATAGCTAGTTTGT
GTTGAGTAGAAAGGATTTCC

Downstream 100 bases:

>100_bases
CCTACTCGTTGAGAGTCGAGAGAGGCAGCAGGATTAATCCTCAAGCTCATTCAAATGCAATTCGATCCGGCGATCAGGCA
AGAGCCACATAATTGCTACC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAHAQTILVTGSSSGLGRAIVETLAQHGHTVFASMRGIAGKNAQAAQELRDFASQHGLNIEPIELDVVNQASVDQAIATI
QAKAGRLDCLINNAGAGLAGLTEACSIEQVQQLFDINVFGALRVSKAVLPLMRQQQAGLLITISSTSTQIVVPFLAAYGA
SKAAEEIMAQSMFYELTSLGIDSVILQLGGYATKFGTNIQVAADQSLNAAYGLAGQFAQGISTGIVAGLEYADNPVDVGN
KINEILAMPSEQRPRKYSMGGGSQGLNELNQQLEPLQAGLISLMQMEPLLLRSQTAS

Sequences:

>Translated_297_residues
MAHAQTILVTGSSSGLGRAIVETLAQHGHTVFASMRGIAGKNAQAAQELRDFASQHGLNIEPIELDVVNQASVDQAIATI
QAKAGRLDCLINNAGAGLAGLTEACSIEQVQQLFDINVFGALRVSKAVLPLMRQQQAGLLITISSTSTQIVVPFLAAYGA
SKAAEEIMAQSMFYELTSLGIDSVILQLGGYATKFGTNIQVAADQSLNAAYGLAGQFAQGISTGIVAGLEYADNPVDVGN
KINEILAMPSEQRPRKYSMGGGSQGLNELNQQLEPLQAGLISLMQMEPLLLRSQTAS
>Mature_296_residues
AHAQTILVTGSSSGLGRAIVETLAQHGHTVFASMRGIAGKNAQAAQELRDFASQHGLNIEPIELDVVNQASVDQAIATIQ
AKAGRLDCLINNAGAGLAGLTEACSIEQVQQLFDINVFGALRVSKAVLPLMRQQQAGLLITISSTSTQIVVPFLAAYGAS
KAAEEIMAQSMFYELTSLGIDSVILQLGGYATKFGTNIQVAADQSLNAAYGLAGQFAQGISTGIVAGLEYADNPVDVGNK
INEILAMPSEQRPRKYSMGGGSQGLNELNQQLEPLQAGLISLMQMEPLLLRSQTAS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=200, Percent_Identity=35.5, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4504503, Length=204, Percent_Identity=32.843137254902, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI223718074, Length=207, Percent_Identity=31.4009661835749, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI119392083, Length=198, Percent_Identity=28.2828282828283, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=26.2135922330097, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI44680136, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI44680133, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI17738292, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI142976729, Length=180, Percent_Identity=26.1111111111111, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI7706318, Length=158, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=176, Percent_Identity=22.7272727272727, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4503817, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=159, Percent_Identity=34.5911949685535, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=238, Percent_Identity=28.9915966386555, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787335, Length=174, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786701, Length=220, Percent_Identity=29.0909090909091, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082100, Length=178, Percent_Identity=33.1460674157303, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.9245283018868, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI115534660, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=174, Percent_Identity=29.8850574712644, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=201, Percent_Identity=34.3283582089552, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=189, Percent_Identity=29.1005291005291, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24651139, Length=187, Percent_Identity=33.1550802139037, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI23397609, Length=207, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=25.5, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=172, Percent_Identity=30.8139534883721, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=179, Percent_Identity=31.8435754189944, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355319, Length=191, Percent_Identity=31.413612565445, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31172; Mature: 31041

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAQTILVTGSSSGLGRAIVETLAQHGHTVFASMRGIAGKNAQAAQELRDFASQHGLNI
CCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEHHHHCCCCCCHHHHHHHHHHHHHCCCCC
EPIELDVVNQASVDQAIATIQAKAGRLDCLINNAGAGLAGLTEACSIEQVQQLFDINVFG
CCEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHCCCHHH
ALRVSKAVLPLMRQQQAGLLITISSTSTQIVVPFLAAYGASKAAEEIMAQSMFYELTSLG
HHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
IDSVILQLGGYATKFGTNIQVAADQSLNAAYGLAGQFAQGISTGIVAGLEYADNPVDVGN
HHHHHHHHCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KINEILAMPSEQRPRKYSMGGGSQGLNELNQQLEPLQAGLISLMQMEPLLLRSQTAS
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC
>Mature Secondary Structure 
AHAQTILVTGSSSGLGRAIVETLAQHGHTVFASMRGIAGKNAQAAQELRDFASQHGLNI
CCCEEEEEECCCCCCHHHHHHHHHHCCCEEEHHHHCCCCCCHHHHHHHHHHHHHCCCCC
EPIELDVVNQASVDQAIATIQAKAGRLDCLINNAGAGLAGLTEACSIEQVQQLFDINVFG
CCEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHCCCHHH
ALRVSKAVLPLMRQQQAGLLITISSTSTQIVVPFLAAYGASKAAEEIMAQSMFYELTSLG
HHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
IDSVILQLGGYATKFGTNIQVAADQSLNAAYGLAGQFAQGISTGIVAGLEYADNPVDVGN
HHHHHHHHCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KINEILAMPSEQRPRKYSMGGGSQGLNELNQQLEPLQAGLISLMQMEPLLLRSQTAS
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]