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The map label for this gene is rsbRA [H]

Identifier: 159899450

GI number: 159899450

Start: 3706287

End: 3707303

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_2931

Alternate gene names: 159899450

Gene position: 3706287-3707303 (Clockwise)

Preceding gene: 159899449

Following gene: 159899452

Centisome position: 58.4

GC content: 49.85

Gene sequence:

>1017_bases
GTGATTGCTGCGCCCCAAATTGCGCTCCAAACATTTTTGAATATTCCTAGCTCGCAAACCCTTAGCCCAAGCCAAACCCT
CGAACTTCAGATGAACCCCACCACCGCGCCAGCATTAGCCAGTGTGCTTGAGCGAATGCAGAATAACCAAAGCGGCATTC
AAACGCTCCAGGCGAACAATCAAGAACTAGTGGTAGCCAACGCTGCACTCACCTCGATCAATTGGCATATTGTGGTGGTT
GCGCCTAAAACCGAGATCACCAGTGAAGCCCAAGCGGTCACCGCCACAATCGAAACCAGTTCAGGCCGAATTGTTGGCAA
ACTGCTGTGGTTTTTGGCAGCCTTGACTATTATCACCCTGCTAGCGACTTGGTTGATCAGCAATCGGCTGAGTCAGCCAA
TCGTGGCGTTGGTGCAAAATACCCAAGCCTTAGCCGAATCGAATCAGTTTGTGCAGTTGCCCGAGCAAAGCAACGATGAG
CTAGGATTTTTGGCTCGCGCCTTCAATCAAATGGCTAGTAAAGTTCAGTCAGCGCAACAAAGTCTCCAACAAGTCAATCA
AAATCTTGAGCAAACCGTGCAGCAACGCACCCATGAGCTAGAACAAGAGCGCGAATCGTTGCAACAAACCCTTGATCAAC
TCCAACAGGCCAATAGTACAGTGGCCAAACTGACCGCGCCAATTATTCCGGTGGCCCAAGGCGTGGTGGTTGTACCAATT
ACTGGTAGCCTGAATACCGAGCGAATCGAGCAATTGCAACAAGCCATGTTGCGCACTGCTGAGCGCCTACGGATTCATAC
CGTAATTCTCGATGTGACCGGACTTGAAGTTTTGGAAGATTCTGCGACCTTTGTCCGCAGCCTTGATGCCTTGCGCTTGC
TTGGTTCAAAAGCAATGTTGGTTGGGGTAAGTGCCGATTTTGCCCAAGATTTGATTCAGAGCGGCATCAATCTTGATTCA
GTTACGACCATGGCCAATCTTCAAGCAGCTGTCCGAGCAACATTAAATCAAGCCTAG

Upstream 100 bases:

>100_bases
GCTTTATTGGTATCGATATTACACTCAATGAATTTTTGAAACAACTTGATACGATTCCACGCCCAGTAGCTATGCTTTTG
TGCTTGATCAACAGGGCGAT

Downstream 100 bases:

>100_bases
AACTTAACGAACCACATAATAAACCCCCGATCCATTTGGTATGGATCGGGGGGTTTGGTTCGATGCGGGTCTAGCGGTCA
GGAATAACATCTAAGAACAA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIAAPQIALQTFLNIPSSQTLSPSQTLELQMNPTTAPALASVLERMQNNQSGIQTLQANNQELVVANAALTSINWHIVVV
APKTEITSEAQAVTATIETSSGRIVGKLLWFLAALTIITLLATWLISNRLSQPIVALVQNTQALAESNQFVQLPEQSNDE
LGFLARAFNQMASKVQSAQQSLQQVNQNLEQTVQQRTHELEQERESLQQTLDQLQQANSTVAKLTAPIIPVAQGVVVVPI
TGSLNTERIEQLQQAMLRTAERLRIHTVILDVTGLEVLEDSATFVRSLDALRLLGSKAMLVGVSADFAQDLIQSGINLDS
VTTMANLQAAVRATLNQA

Sequences:

>Translated_338_residues
MIAAPQIALQTFLNIPSSQTLSPSQTLELQMNPTTAPALASVLERMQNNQSGIQTLQANNQELVVANAALTSINWHIVVV
APKTEITSEAQAVTATIETSSGRIVGKLLWFLAALTIITLLATWLISNRLSQPIVALVQNTQALAESNQFVQLPEQSNDE
LGFLARAFNQMASKVQSAQQSLQQVNQNLEQTVQQRTHELEQERESLQQTLDQLQQANSTVAKLTAPIIPVAQGVVVVPI
TGSLNTERIEQLQQAMLRTAERLRIHTVILDVTGLEVLEDSATFVRSLDALRLLGSKAMLVGVSADFAQDLIQSGINLDS
VTTMANLQAAVRATLNQA
>Mature_338_residues
MIAAPQIALQTFLNIPSSQTLSPSQTLELQMNPTTAPALASVLERMQNNQSGIQTLQANNQELVVANAALTSINWHIVVV
APKTEITSEAQAVTATIETSSGRIVGKLLWFLAALTIITLLATWLISNRLSQPIVALVQNTQALAESNQFVQLPEQSNDE
LGFLARAFNQMASKVQSAQQSLQQVNQNLEQTVQQRTHELEQERESLQQTLDQLQQANSTVAKLTAPIIPVAQGVVVVPI
TGSLNTERIEQLQQAMLRTAERLRIHTVILDVTGLEVLEDSATFVRSLDALRLLGSKAMLVGVSADFAQDLIQSGINLDS
VTTMANLQAAVRATLNQA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 36654; Mature: 36654

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50885 HAMP ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAPQIALQTFLNIPSSQTLSPSQTLELQMNPTTAPALASVLERMQNNQSGIQTLQANN
CCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHCCC
QELVVANAALTSINWHIVVVAPKTEITSEAQAVTATIETSSGRIVGKLLWFLAALTIITL
CEEEEEEEEEEEECEEEEEEECCCHHCCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHH
LATWLISNRLSQPIVALVQNTQALAESNQFVQLPEQSNDELGFLARAFNQMASKVQSAQQ
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLQQVNQNLEQTVQQRTHELEQERESLQQTLDQLQQANSTVAKLTAPIIPVAQGVVVVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHCCEEEEEE
TGSLNTERIEQLQQAMLRTAERLRIHTVILDVTGLEVLEDSATFVRSLDALRLLGSKAML
CCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VGVSADFAQDLIQSGINLDSVTTMANLQAAVRATLNQA
EECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAAPQIALQTFLNIPSSQTLSPSQTLELQMNPTTAPALASVLERMQNNQSGIQTLQANN
CCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHCCC
QELVVANAALTSINWHIVVVAPKTEITSEAQAVTATIETSSGRIVGKLLWFLAALTIITL
CEEEEEEEEEEEECEEEEEEECCCHHCCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHH
LATWLISNRLSQPIVALVQNTQALAESNQFVQLPEQSNDELGFLARAFNQMASKVQSAQQ
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLQQVNQNLEQTVQQRTHELEQERESLQQTLDQLQQANSTVAKLTAPIIPVAQGVVVVPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHCCEEEEEE
TGSLNTERIEQLQQAMLRTAERLRIHTVILDVTGLEVLEDSATFVRSLDALRLLGSKAML
CCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VGVSADFAQDLIQSGINLDSVTTMANLQAAVRATLNQA
EECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]