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The map label for this gene is menH [H]

Identifier: 159899328

GI number: 159899328

Start: 3570743

End: 3571558

Strand: Direct

Name: menH [H]

Synonym: Haur_2809

Alternate gene names: 159899328

Gene position: 3570743-3571558 (Clockwise)

Preceding gene: 159899327

Following gene: 159899329

Centisome position: 56.26

GC content: 45.47

Gene sequence:

>816_bases
ATGAGTAATCAATTAAGCGCTAAAACGATTAATATACACGATTTTGATTTACACTACTATACCGTAGGCAACCCCGACAA
CCCAGCTTTGATCTTAATTCATCCAGCGTTTGGCGATCATCAATGCTTTGCTCAGCAGATTGATAGCTTCGCCAAATTGC
ATTATGTCATCTTAATCGATTTACCTGGTCATGGTCGTTCGCAACCAAGCAAAGCCTTGATTGGCATCGAACGCACACCT
GAATATTTGGCCGCCATCTTGCAAAACGAAAACCAAGCACAAGCTCATGTGTTGGGCGTTTCGCTTGGCTCGTTGATCGC
TCAAGAATTCGCCTATCGGTATCCGCATTTGGTGGCTAGCGTGACGGTTGTTGGTGGCTACAGTATTTTTGGCGATCAAC
GGGCGGTGATGCGGGCGCAACGCAAAGAAATGCTCAAATGGATGTTCATGGTGCTATTTTCAATTGAGCGTTTTCGGCGC
TATGTGGCAAAGATCAGCGTGTTTTATTCGGCTGGTCAGGAATTATTTTATCAACGTATGCAGTTTTTTTCGCGCTCATC
ATTTCGCTTGATGAGCAAGTTGAATCAAATTATGCATCCAAACGAAGTAGCACCCCAACAAAAACTCTTGGTTTTGGTGG
GCGAGCACGATCAGCCAATTGCCTTGCAAGCAGCCCGCGAATGGCAACAACAGCAACCAACGATCGACTACCATGTGCTA
CCAAACGCTGGGCATTGCGCCAATATGGATAATCCAACGCTTTTCAATCAATTGGTGCTCGATTTTCTGCATTCCGCCCC
AAAACCGCATAATTAA

Upstream 100 bases:

>100_bases
GCCGATTTTCAATGGCTAACCTTGGAATATGGTGTAGCCTACTACAGTTTCAATATTAATTGGTATCAACAACTGCTAAG
CAAACTTGAGGAATCTGGCA

Downstream 100 bases:

>100_bases
TCCTGTAACAACTGCGTAACATCGCGGCGCTATGCTCAAAATATATCATTTTGAAGCAAACGAGGCCGCAATGCAAACAC
TCCTTTGGTGGATTTACTGG

Product: alpha/beta hydrolase fold-domain containing protein

Products: NA

Alternate protein names: SHCHC synthase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSNQLSAKTINIHDFDLHYYTVGNPDNPALILIHPAFGDHQCFAQQIDSFAKLHYVILIDLPGHGRSQPSKALIGIERTP
EYLAAILQNENQAQAHVLGVSLGSLIAQEFAYRYPHLVASVTVVGGYSIFGDQRAVMRAQRKEMLKWMFMVLFSIERFRR
YVAKISVFYSAGQELFYQRMQFFSRSSFRLMSKLNQIMHPNEVAPQQKLLVLVGEHDQPIALQAAREWQQQQPTIDYHVL
PNAGHCANMDNPTLFNQLVLDFLHSAPKPHN

Sequences:

>Translated_271_residues
MSNQLSAKTINIHDFDLHYYTVGNPDNPALILIHPAFGDHQCFAQQIDSFAKLHYVILIDLPGHGRSQPSKALIGIERTP
EYLAAILQNENQAQAHVLGVSLGSLIAQEFAYRYPHLVASVTVVGGYSIFGDQRAVMRAQRKEMLKWMFMVLFSIERFRR
YVAKISVFYSAGQELFYQRMQFFSRSSFRLMSKLNQIMHPNEVAPQQKLLVLVGEHDQPIALQAAREWQQQQPTIDYHVL
PNAGHCANMDNPTLFNQLVLDFLHSAPKPHN
>Mature_270_residues
SNQLSAKTINIHDFDLHYYTVGNPDNPALILIHPAFGDHQCFAQQIDSFAKLHYVILIDLPGHGRSQPSKALIGIERTPE
YLAAILQNENQAQAHVLGVSLGSLIAQEFAYRYPHLVASVTVVGGYSIFGDQRAVMRAQRKEMLKWMFMVLFSIERFRRY
VAKISVFYSAGQELFYQRMQFFSRSSFRLMSKLNQIMHPNEVAPQQKLLVLVGEHDQPIALQAAREWQQQQPTIDYHVLP
NAGHCANMDNPTLFNQLVLDFLHSAPKPHN

Specific function: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. MenH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =4.2.99.20 [H]

Molecular weight: Translated: 30916; Mature: 30785

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQLSAKTINIHDFDLHYYTVGNPDNPALILIHPAFGDHQCFAQQIDSFAKLHYVILID
CCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEEEEE
LPGHGRSQPSKALIGIERTPEYLAAILQNENQAQAHVLGVSLGSLIAQEFAYRYPHLVAS
CCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VTVVGGYSIFGDQRAVMRAQRKEMLKWMFMVLFSIERFRRYVAKISVFYSAGQELFYQRM
HHEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFFSRSSFRLMSKLNQIMHPNEVAPQQKLLVLVGEHDQPIALQAAREWQQQQPTIDYHVL
HHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEC
PNAGHCANMDNPTLFNQLVLDFLHSAPKPHN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNQLSAKTINIHDFDLHYYTVGNPDNPALILIHPAFGDHQCFAQQIDSFAKLHYVILID
CCCCCCEEEEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEEEEE
LPGHGRSQPSKALIGIERTPEYLAAILQNENQAQAHVLGVSLGSLIAQEFAYRYPHLVAS
CCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VTVVGGYSIFGDQRAVMRAQRKEMLKWMFMVLFSIERFRRYVAKISVFYSAGQELFYQRM
HHEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFFSRSSFRLMSKLNQIMHPNEVAPQQKLLVLVGEHDQPIALQAAREWQQQQPTIDYHVL
HHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEC
PNAGHCANMDNPTLFNQLVLDFLHSAPKPHN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA