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The map label for this gene is pkn1 [H]

Identifier: 159898226

GI number: 159898226

Start: 1979863

End: 1981395

Strand: Reverse

Name: pkn1 [H]

Synonym: Haur_1702

Alternate gene names: 159898226

Gene position: 1981395-1979863 (Counterclockwise)

Preceding gene: 159898230

Following gene: 159898225

Centisome position: 31.22

GC content: 44.29

Gene sequence:

>1533_bases
ATGACGGTTTCGCCAACATTTGCGGTACAGTTAAGCCAACTCAAACAAACAGCATCGATGTCAATCCGAGTCTTAAGCCA
AAAAACCGCCATCCCCGAAGATACGCTCGACGATTGGTTAAAAGGCAAAAGTCGGCCACGCAATTGGGAACGGGTGATCA
TCGTTGCGGCGGCACTCCAAGCCAATTATCAGCAAGCGAACAACCTCTTACAAGCCATCAAAACTTCACCACTTGAACTA
CTACCATGGCATCAAATTGAATATTTTATTCAGCCACGTGAACAACAGATTGGCACAAATGTGCATAAGCAAACCATTAA
TCCAATTTTAGCAATGGTCCAAACATGGTATGAGGCGCAAATCCAATTGCTGCAACAGGAGGTAAAGGCTGATTCAGTTG
ATCACGTAGAAGCACATAATCCTCAATTAGCACCAACAACTGAAGTTAAGCCAAATCCAAGTGATCCAATTGCTATCATA
CACACGGAAATTCACGAGCAAACAAAACATCAAAAACATATAAATCTAAGTCTACCCAAAAAACGTTTGTTGTGGTTATT
TGGCATTAGTAGCATTACGATTATGCTCATGGGGCTGAATCTGCAACATGCGAAATCAAACGATCAATCAGTAATAGACA
TTCCATCGCAACACAATTCAAATCTTACTAACTCCATGATTACAATTCCGGCTGGATTTTTCATTCAGGGAAGTAATTAT
GCTGATATCGCATACTATGCTCAATTATGTATTGATTATGGTGCTGCCTGTACAGAATTAGAGTTTGATGATGAATTTGA
TCAAAATGGCCAAGCGCGTCAGGTATTTCTGAATAGCTACCGCATTGATAAATATGAAGTAACGAATGCTCAATTTGCCC
AATTCGTTGAGCAAACTCAGTATATAACCTACGCTGAACGCCAAGGAGAGAGCATGATTCTTGAGGTTATCGAAACGGCT
GGCTCTAAGGAAACACTGAACTTTAGCGCGATTAAAGGCGCTTTTTGGAAACAACCATACGGCCCCAATTCATCAATTGA
CGACAAAGCCGATTATCCAGTCATTCATATTCACTATGAAGATGCAGTGGCGTACTGCACAGCCAAGCATAAACGATTGC
CCACCGAAGCCGAGTGGGAGAAAGCGGCGCGAGGCGTTGAAGGGTGGCGATTTCCGTGGGGCAATGAGTGGAAGTCTGGC
TTAAGCAATCATGCGATTCCGCTGCGATCCCATATTTTACAAGTTCGTGGTTTACAAGCAATTGGCCAATCTCCGCAAAG
TATCAGCCCATATGGGGTACACGACCTCTTAGGGAACGTAAGCGAGTGGACTGCCGATTGGTATCAGCCAAGCTATTATC
AAAATAATCCTGCTAGCCAAAACCCTCAAGGTCCCGAGCTAGGCAACAGCCATGTCAAGCGTGGAGGGAGTTGGGCAACA
CCACCTGGCTATCTGCATAATAGTTGGCGGATTGGCACTCCCGACCAAACAACCGATCGCTTAGGCTTTCGCTGCGCCGC
CGATGTAAATTAA

Upstream 100 bases:

>100_bases
AGCCAATCGGAGAATGAACAGGGATTAAGGAGCAAACCAAGGGGGAATGAGGGGGGAAATGGGGTGAAAAAGAGTGTGTA
TCACGGTTGGAGGATTTTTA

Downstream 100 bases:

>100_bases
AAACAAAAGCCTCCGTTGGATTACCAACGGAGGCTTTGTGGAGCGGTACGCATCCCCCTACGTTCCCACAGCGGGTGCTG
CAGTAGCCTCGGTGTGTGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTVSPTFAVQLSQLKQTASMSIRVLSQKTAIPEDTLDDWLKGKSRPRNWERVIIVAAALQANYQQANNLLQAIKTSPLEL
LPWHQIEYFIQPREQQIGTNVHKQTINPILAMVQTWYEAQIQLLQQEVKADSVDHVEAHNPQLAPTTEVKPNPSDPIAII
HTEIHEQTKHQKHINLSLPKKRLLWLFGISSITIMLMGLNLQHAKSNDQSVIDIPSQHNSNLTNSMITIPAGFFIQGSNY
ADIAYYAQLCIDYGAACTELEFDDEFDQNGQARQVFLNSYRIDKYEVTNAQFAQFVEQTQYITYAERQGESMILEVIETA
GSKETLNFSAIKGAFWKQPYGPNSSIDDKADYPVIHIHYEDAVAYCTAKHKRLPTEAEWEKAARGVEGWRFPWGNEWKSG
LSNHAIPLRSHILQVRGLQAIGQSPQSISPYGVHDLLGNVSEWTADWYQPSYYQNNPASQNPQGPELGNSHVKRGGSWAT
PPGYLHNSWRIGTPDQTTDRLGFRCAADVN

Sequences:

>Translated_510_residues
MTVSPTFAVQLSQLKQTASMSIRVLSQKTAIPEDTLDDWLKGKSRPRNWERVIIVAAALQANYQQANNLLQAIKTSPLEL
LPWHQIEYFIQPREQQIGTNVHKQTINPILAMVQTWYEAQIQLLQQEVKADSVDHVEAHNPQLAPTTEVKPNPSDPIAII
HTEIHEQTKHQKHINLSLPKKRLLWLFGISSITIMLMGLNLQHAKSNDQSVIDIPSQHNSNLTNSMITIPAGFFIQGSNY
ADIAYYAQLCIDYGAACTELEFDDEFDQNGQARQVFLNSYRIDKYEVTNAQFAQFVEQTQYITYAERQGESMILEVIETA
GSKETLNFSAIKGAFWKQPYGPNSSIDDKADYPVIHIHYEDAVAYCTAKHKRLPTEAEWEKAARGVEGWRFPWGNEWKSG
LSNHAIPLRSHILQVRGLQAIGQSPQSISPYGVHDLLGNVSEWTADWYQPSYYQNNPASQNPQGPELGNSHVKRGGSWAT
PPGYLHNSWRIGTPDQTTDRLGFRCAADVN
>Mature_509_residues
TVSPTFAVQLSQLKQTASMSIRVLSQKTAIPEDTLDDWLKGKSRPRNWERVIIVAAALQANYQQANNLLQAIKTSPLELL
PWHQIEYFIQPREQQIGTNVHKQTINPILAMVQTWYEAQIQLLQQEVKADSVDHVEAHNPQLAPTTEVKPNPSDPIAIIH
TEIHEQTKHQKHINLSLPKKRLLWLFGISSITIMLMGLNLQHAKSNDQSVIDIPSQHNSNLTNSMITIPAGFFIQGSNYA
DIAYYAQLCIDYGAACTELEFDDEFDQNGQARQVFLNSYRIDKYEVTNAQFAQFVEQTQYITYAERQGESMILEVIETAG
SKETLNFSAIKGAFWKQPYGPNSSIDDKADYPVIHIHYEDAVAYCTAKHKRLPTEAEWEKAARGVEGWRFPWGNEWKSGL
SNHAIPLRSHILQVRGLQAIGQSPQSISPYGVHDLLGNVSEWTADWYQPSYYQNNPASQNPQGPELGNSHVKRGGSWATP
PGYLHNSWRIGTPDQTTDRLGFRCAADVN

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=308, Percent_Identity=34.0909090909091, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI257470975, Length=300, Percent_Identity=34, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI257470977, Length=303, Percent_Identity=32.3432343234323, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI194248088, Length=312, Percent_Identity=34.6153846153846, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI194248087, Length=304, Percent_Identity=33.8815789473684, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI226437577, Length=206, Percent_Identity=39.8058252427184, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI194248090, Length=182, Percent_Identity=34.6153846153846, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20130397, Length=271, Percent_Identity=35.0553505535055, Blast_Score=137, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 57629; Mature: 57498

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSPTFAVQLSQLKQTASMSIRVLSQKTAIPEDTLDDWLKGKSRPRNWERVIIVAAALQ
CCCCCHHHHHHHHHHHHHHHEEEEEHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHHH
ANYQQANNLLQAIKTSPLELLPWHQIEYFIQPREQQIGTNVHKQTINPILAMVQTWYEAQ
HHHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
IQLLQQEVKADSVDHVEAHNPQLAPTTEVKPNPSDPIAIIHTEIHEQTKHQKHINLSLPK
HHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCEEECCCCH
KRLLWLFGISSITIMLMGLNLQHAKSNDQSVIDIPSQHNSNLTNSMITIPAGFFIQGSNY
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCCCCCCEEEECCCEEEECCCC
ADIAYYAQLCIDYGAACTELEFDDEFDQNGQARQVFLNSYRIDKYEVTNAQFAQFVEQTQ
CHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHH
YITYAERQGESMILEVIETAGSKETLNFSAIKGAFWKQPYGPNSSIDDKADYPVIHIHYE
HHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHCCHHHCCCCCCCCCCCCCCCCCEEEEEEC
DAVAYCTAKHKRLPTEAEWEKAARGVEGWRFPWGNEWKSGLSNHAIPLRSHILQVRGLQA
CHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
IGQSPQSISPYGVHDLLGNVSEWTADWYQPSYYQNNPASQNPQGPELGNSHVKRGGSWAT
HCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCC
PPGYLHNSWRIGTPDQTTDRLGFRCAADVN
CCCCCCCCEECCCCCCCHHHCCCEEECCCC
>Mature Secondary Structure 
TVSPTFAVQLSQLKQTASMSIRVLSQKTAIPEDTLDDWLKGKSRPRNWERVIIVAAALQ
CCCCHHHHHHHHHHHHHHHEEEEEHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHHH
ANYQQANNLLQAIKTSPLELLPWHQIEYFIQPREQQIGTNVHKQTINPILAMVQTWYEAQ
HHHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
IQLLQQEVKADSVDHVEAHNPQLAPTTEVKPNPSDPIAIIHTEIHEQTKHQKHINLSLPK
HHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCEEECCCCH
KRLLWLFGISSITIMLMGLNLQHAKSNDQSVIDIPSQHNSNLTNSMITIPAGFFIQGSNY
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCCCCCCEEEECCCEEEECCCC
ADIAYYAQLCIDYGAACTELEFDDEFDQNGQARQVFLNSYRIDKYEVTNAQFAQFVEQTQ
CHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHH
YITYAERQGESMILEVIETAGSKETLNFSAIKGAFWKQPYGPNSSIDDKADYPVIHIHYE
HHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHCCHHHCCCCCCCCCCCCCCCCCEEEEEEC
DAVAYCTAKHKRLPTEAEWEKAARGVEGWRFPWGNEWKSGLSNHAIPLRSHILQVRGLQA
CHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
IGQSPQSISPYGVHDLLGNVSEWTADWYQPSYYQNNPASQNPQGPELGNSHVKRGGSWAT
HCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCC
PPGYLHNSWRIGTPDQTTDRLGFRCAADVN
CCCCCCCCEECCCCCCCHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]