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The map label for this gene is arnC [H]

Identifier: 159897981

GI number: 159897981

Start: 1695525

End: 1696250

Strand: Reverse

Name: arnC [H]

Synonym: Haur_1456

Alternate gene names: 159897981

Gene position: 1696250-1695525 (Counterclockwise)

Preceding gene: 159897984

Following gene: 159897979

Centisome position: 26.73

GC content: 52.62

Gene sequence:

>726_bases
GTGAAAAGCATCACGGTGGCCTTACCCGCCTATAACGAAGCTGAAAATATTCCGGCCATGGTTGAGGAAGTGGTCAATAC
CCTCGAAAGCCTTGGCCGCGCCTATGAAGTTATTGTCGTCAACGATGGGAGCCGCGATAATACTGCGGCGGTTGTGCGTG
ACCTAGAAGCCCGCTATCCGCATGTTCGGTTGGTCGATCATGCGGTGAACCAAGGCTATGGCGCTGCGGTCTGGACAGGC
TTGACCAGCGCAAAAACCGATTTGGTCTTTTTTACTGATGCTGATCGTCAATTTGACCTTGGTGAGTTACCCAAATTGCT
GGCCAAAATTGATCAAGCCGATTTGGTGGTTGGCTATCGCTCACCACGCCGCGACCCGCTGATGCGCCGCTTAAACGGTT
GGGGCTGGAGCCGTCTGGTCACCTTGTTGTTTGGCTATACCGCCCGCGATATTGATTGCGCCTTTAAATTGATGCAACGC
CATGTCGTTGATACGCTCAAAACTGAGGTTCAATCACGTGGGGCTACGTTTAGCGCCGAATTTTTGGTTCGCGCCAAACG
GGCTGGCTTTCGCTTTGAAGAAGTTGCGATCAATGGCCATCGCCCACGGGTAGCAGGCAACCCGACCGGAGCCAAATTGA
GCGTGATTTTGCGAGCCTTCCGCGAATTGATTGCCGTTCGCAGCGAATTAGCCCGCCAAGAACAAACCAAAGCCAAACAT
ATTTAA

Upstream 100 bases:

>100_bases
TTTTATTGCGGTTAAAGGCTTTATGCTACAATAGTTGCTTGCAAGCCCATGCGTGGAGGGCTGCACTTAACCCTATCTGC
GAACAATGGGAGTTCTCAAC

Downstream 100 bases:

>100_bases
CTTTCGATCTGCAACAGTCCCACACTCCATTGATTAAGTGTGGGACTGCGATTTTAGCGAGCGGCCCATTCACCACTAAA
TTGATTCAAGCACATTCAGC

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKSITVALPAYNEAENIPAMVEEVVNTLESLGRAYEVIVVNDGSRDNTAAVVRDLEARYPHVRLVDHAVNQGYGAAVWTG
LTSAKTDLVFFTDADRQFDLGELPKLLAKIDQADLVVGYRSPRRDPLMRRLNGWGWSRLVTLLFGYTARDIDCAFKLMQR
HVVDTLKTEVQSRGATFSAEFLVRAKRAGFRFEEVAINGHRPRVAGNPTGAKLSVILRAFRELIAVRSELARQEQTKAKH
I

Sequences:

>Translated_241_residues
MKSITVALPAYNEAENIPAMVEEVVNTLESLGRAYEVIVVNDGSRDNTAAVVRDLEARYPHVRLVDHAVNQGYGAAVWTG
LTSAKTDLVFFTDADRQFDLGELPKLLAKIDQADLVVGYRSPRRDPLMRRLNGWGWSRLVTLLFGYTARDIDCAFKLMQR
HVVDTLKTEVQSRGATFSAEFLVRAKRAGFRFEEVAINGHRPRVAGNPTGAKLSVILRAFRELIAVRSELARQEQTKAKH
I
>Mature_241_residues
MKSITVALPAYNEAENIPAMVEEVVNTLESLGRAYEVIVVNDGSRDNTAAVVRDLEARYPHVRLVDHAVNQGYGAAVWTG
LTSAKTDLVFFTDADRQFDLGELPKLLAKIDQADLVVGYRSPRRDPLMRRLNGWGWSRLVTLLFGYTARDIDCAFKLMQR
HVVDTLKTEVQSRGATFSAEFLVRAKRAGFRFEEVAINGHRPRVAGNPTGAKLSVILRAFRELIAVRSELARQEQTKAKH
I

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=203, Percent_Identity=29.5566502463054, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7019323, Length=217, Percent_Identity=28.110599078341, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1788588, Length=170, Percent_Identity=33.5294117647059, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787259, Length=100, Percent_Identity=38, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788692, Length=166, Percent_Identity=28.9156626506024, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71999402, Length=203, Percent_Identity=29.5566502463054, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146207, Length=216, Percent_Identity=27.3148148148148, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325029, Length=249, Percent_Identity=24.4979919678715, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24585265, Length=204, Percent_Identity=29.9019607843137, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24582769, Length=214, Percent_Identity=30.3738317757009, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 26965; Mature: 26965

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSITVALPAYNEAENIPAMVEEVVNTLESLGRAYEVIVVNDGSRDNTAAVVRDLEARYP
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHCCC
HVRLVDHAVNQGYGAAVWTGLTSAKTDLVFFTDADRQFDLGELPKLLAKIDQADLVVGYR
CHHHHHHHHCCCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHEEEECC
SPRRDPLMRRLNGWGWSRLVTLLFGYTARDIDCAFKLMQRHVVDTLKTEVQSRGATFSAE
CCCCCHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
FLVRAKRAGFRFEEVAINGHRPRVAGNPTGAKLSVILRAFRELIAVRSELARQEQTKAKH
HHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure
MKSITVALPAYNEAENIPAMVEEVVNTLESLGRAYEVIVVNDGSRDNTAAVVRDLEARYP
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHCCC
HVRLVDHAVNQGYGAAVWTGLTSAKTDLVFFTDADRQFDLGELPKLLAKIDQADLVVGYR
CHHHHHHHHCCCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHEEEECC
SPRRDPLMRRLNGWGWSRLVTLLFGYTARDIDCAFKLMQRHVVDTLKTEVQSRGATFSAE
CCCCCHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
FLVRAKRAGFRFEEVAINGHRPRVAGNPTGAKLSVILRAFRELIAVRSELARQEQTKAKH
HHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA