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The map label for this gene is ycgM [C]

Identifier: 159897737

GI number: 159897737

Start: 1391392

End: 1392420

Strand: Reverse

Name: ycgM [C]

Synonym: Haur_1208

Alternate gene names: 159897737

Gene position: 1392420-1391392 (Counterclockwise)

Preceding gene: 159897742

Following gene: 159897734

Centisome position: 21.94

GC content: 53.94

Gene sequence:

>1029_bases
ATGAAATTTGTTTCATTTCGGCGCTATGGCGAAGGCTCCGAGGCACGAGCCGGGGCTTGGTTGCCCATGGGAATCATCGA
TCTACAAGCCGCAGCAGGCTTAGTTTTTGAAGATTTGCCCCACGATTGGTCGCTGATGAGCATGCTCAAACACGAAGCCG
ATGGCTATGGCATCGATGCCGCAATCCAGGTCGTTTCAGCAGTCGTCGATTTGCTCGGCGGTGGCGGCGATGGCATCGAA
TGGGATGATCCCGATGCGATCAACAGTATGCTTTCGCTAGGCGGCGAAACCGTGATTTACCCGCCTGATAGCGTGCGTTT
GTTAGCGCCGATTCCTCAACCACCAACGATTCGCGATTTTTATGCCTTCGAGCAGCATGTGCGTGAAATTCGTGCTCAGC
ATGGCCGCTCCGTGCCTAGCACGTGGTACGATATGCCAGTCTTTTACTTTGGTAACCCTACCACCGTGCTTGGGCCAGAT
AGCGATCTGGTAATGCCGCGCACCAGTCAACTTGATTATGAACTGGAAATTGCAGCAGTTATTGGCCGGCCATGTCGCGA
TATCGAGCCAGATGAAGCTGAATATTATATTGCTGGCTTGATGGTCATGAATGATTGGTCGGCCCGCGATATTCAGGCCC
GCGAGATGAGCGTTGGCTTGGGGCCAGCCAAGGGCAAAGATTTTGCCACCTCATTCGGGCCAGCCCTGATCACGCTTGAC
GAAATTGAGGATAAAGCGCTGGGCGATGGGCGTTACGATTTGGCGATGGTGGTGCGGGTCAATGGTGAAGAGCGTGGTCG
TGCGTCGTTCGCCGATATTTACTATACGCTCGGCGAATTGATTGCCCACGCTTCACGCGATGTCACCCTGCTGCCTGGTG
AAATTATTGGCTCGGGCACAGTTGGCACTGGCTGTTTGCTCGAAACCACCCACGGCGAAGGGCCATGGCTTGAGGTTGGC
GATGTGGTCGAACTCGAAATCGAACGCATCGGCATCTTACGCAACACAATTGTTGATCGCGATAGCTAA

Upstream 100 bases:

>100_bases
CTGCGTCTCTGCGTTAAAAACCGATCTCTAGCCAAATTCTATGTTCTAACACCCTCAACTCTCATCTATAATTGAACTAC
TATTTAAAAGAGGGCTTCTT

Downstream 100 bases:

>100_bases
TTAATCGCTATGTGGTGGCAGCCCAAACAACTGCCACCACATTGATCGCAAGCTAGACTTGACCCAAGGCAACCTGCTTT
GGTGCTTGCCGAGCCAGAAT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKFVSFRRYGEGSEARAGAWLPMGIIDLQAAAGLVFEDLPHDWSLMSMLKHEADGYGIDAAIQVVSAVVDLLGGGGDGIE
WDDPDAINSMLSLGGETVIYPPDSVRLLAPIPQPPTIRDFYAFEQHVREIRAQHGRSVPSTWYDMPVFYFGNPTTVLGPD
SDLVMPRTSQLDYELEIAAVIGRPCRDIEPDEAEYYIAGLMVMNDWSARDIQAREMSVGLGPAKGKDFATSFGPALITLD
EIEDKALGDGRYDLAMVVRVNGEERGRASFADIYYTLGELIAHASRDVTLLPGEIIGSGTVGTGCLLETTHGEGPWLEVG
DVVELEIERIGILRNTIVDRDS

Sequences:

>Translated_342_residues
MKFVSFRRYGEGSEARAGAWLPMGIIDLQAAAGLVFEDLPHDWSLMSMLKHEADGYGIDAAIQVVSAVVDLLGGGGDGIE
WDDPDAINSMLSLGGETVIYPPDSVRLLAPIPQPPTIRDFYAFEQHVREIRAQHGRSVPSTWYDMPVFYFGNPTTVLGPD
SDLVMPRTSQLDYELEIAAVIGRPCRDIEPDEAEYYIAGLMVMNDWSARDIQAREMSVGLGPAKGKDFATSFGPALITLD
EIEDKALGDGRYDLAMVVRVNGEERGRASFADIYYTLGELIAHASRDVTLLPGEIIGSGTVGTGCLLETTHGEGPWLEVG
DVVELEIERIGILRNTIVDRDS
>Mature_342_residues
MKFVSFRRYGEGSEARAGAWLPMGIIDLQAAAGLVFEDLPHDWSLMSMLKHEADGYGIDAAIQVVSAVVDLLGGGGDGIE
WDDPDAINSMLSLGGETVIYPPDSVRLLAPIPQPPTIRDFYAFEQHVREIRAQHGRSVPSTWYDMPVFYFGNPTTVLGPD
SDLVMPRTSQLDYELEIAAVIGRPCRDIEPDEAEYYIAGLMVMNDWSARDIQAREMSVGLGPAKGKDFATSFGPALITLD
EIEDKALGDGRYDLAMVVRVNGEERGRASFADIYYTLGELIAHASRDVTLLPGEIIGSGTVGTGCLLETTHGEGPWLEVG
DVVELEIERIGILRNTIVDRDS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI40786394, Length=250, Percent_Identity=29.6, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4557587, Length=228, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI66348062, Length=181, Percent_Identity=29.8342541436464, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI215422413, Length=181, Percent_Identity=29.8342541436464, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13654274, Length=181, Percent_Identity=29.8342541436464, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17568863, Length=229, Percent_Identity=27.9475982532751, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28572127, Length=238, Percent_Identity=30.2521008403361, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24663695, Length=237, Percent_Identity=28.6919831223629, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24657182, Length=248, Percent_Identity=27.8225806451613, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 37337; Mature: 37337

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVSFRRYGEGSEARAGAWLPMGIIDLQAAAGLVFEDLPHDWSLMSMLKHEADGYGIDA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHCCCCCHHHHHHHHHCCCCCCHHH
AIQVVSAVVDLLGGGGDGIEWDDPDAINSMLSLGGETVIYPPDSVRLLAPIPQPPTIRDF
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCHHHH
YAFEQHVREIRAQHGRSVPSTWYDMPVFYFGNPTTVLGPDSDLVMPRTSQLDYELEIAAV
HHHHHHHHHHHHHHCCCCCCCHHCCEEEEECCCEEEECCCCCEECCCCCCCCEEEEEEEE
IGRPCRDIEPDEAEYYIAGLMVMNDWSARDIQAREMSVGLGPAKGKDFATSFGPALITLD
CCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHEEECCCCCCCCCCHHCCCCEEEEEE
EIEDKALGDGRYDLAMVVRVNGEERGRASFADIYYTLGELIAHASRDVTLLPGEIIGSGT
HHCCHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCC
VGTGCLLETTHGEGPWLEVGDVVELEIERIGILRNTIVDRDS
CCCCEEEECCCCCCCCEECCCEEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFVSFRRYGEGSEARAGAWLPMGIIDLQAAAGLVFEDLPHDWSLMSMLKHEADGYGIDA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHCCCCCHHHHHHHHHCCCCCCHHH
AIQVVSAVVDLLGGGGDGIEWDDPDAINSMLSLGGETVIYPPDSVRLLAPIPQPPTIRDF
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCHHHH
YAFEQHVREIRAQHGRSVPSTWYDMPVFYFGNPTTVLGPDSDLVMPRTSQLDYELEIAAV
HHHHHHHHHHHHHHCCCCCCCHHCCEEEEECCCEEEECCCCCEECCCCCCCCEEEEEEEE
IGRPCRDIEPDEAEYYIAGLMVMNDWSARDIQAREMSVGLGPAKGKDFATSFGPALITLD
CCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHEEECCCCCCCCCCHHCCCCEEEEEE
EIEDKALGDGRYDLAMVVRVNGEERGRASFADIYYTLGELIAHASRDVTLLPGEIIGSGT
HHCCHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCC
VGTGCLLETTHGEGPWLEVGDVVELEIERIGILRNTIVDRDS
CCCCEEEECCCCCCCCEECCCEEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]