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The map label for this gene is cobQ

Identifier: 159897580

GI number: 159897580

Start: 1199666

End: 1201135

Strand: Reverse

Name: cobQ

Synonym: Haur_1051

Alternate gene names: 159897580

Gene position: 1201135-1199666 (Counterclockwise)

Preceding gene: 159897581

Following gene: 159897577

Centisome position: 18.93

GC content: 50.54

Gene sequence:

>1470_bases
ATGCTAGCCCCAGTTTTGATGGTTGTCGGAACCGCCTCATCAGTTGGTAAAAGCACCTTGGTTAGTGCACTTTGCCGCAT
TGCTGCCCGCCGTGGCATTCGCGTCGCACCCTTCAAAGCCCAAAATATGAGCAATAATGCTGCTGTTACCGCCAATGGCG
AAGAAATTGCTCGTAGCATTGCCGTCCAAGCAGCGGCAGCCAAACTCACGCCCAGCGTGCAGATGAACCCAATTTTGATT
AAGCCCGAAGGTCAACGTCGTAGCCAAATTATTGTGCAAGGCCGACCGTGGCAGACGCTTGAGGCAATTGATTATTGGCA
ACGCAAACAGCTGCTCTGGGAGATTGTCACCAACAGCCTCGATCAGTTGCGCCAAGCATACGATTTGGTGATAGCTGAGG
GCGCTGGTAGTCCAGTGGAATTGAATCTCAAGGCTCACGACATTACCAATATGCGCGTGGCAACTTATGCTCAAGCCCAA
ACGTTGTTGGTCGGCGATATTGATGTTGGTGGAATTTTCGCGGCGATGTTGGGCACATTGATGCTCTTGGAGCCAGAGGA
GCGTCAATTAATTGCTGGCTTAATTGTCAATCGCTTTCGTGGCGACCCCGATTTATTTACTGATGGTATTCAGATTCTCG
AACAACGCAGCAACAAACCTGTCTTGGGGGTTGTGCCATGGTTGCCGCAACTTGGCTTGCCCGAAGAAGATGCAGTTGCT
TTGGAACGACCTGATCAAACAACCAACAACGCGGCACTAACGATTGGGGTGATTCAACTGCCAGCAATCGCCAACTTCGA
CGATTTTGATCCGTTGGCCCAAGAACAGGGCGTAGCAGTACGTTACATCAACCAGCCGCATGAATTACAGCATTGCCAAG
CACTAATTTTGCCAGGCACAAAACACACGCTGGCTGCCCGGCAATGGCTCACCGAACAAGGCTTCGATCAAGCAATTCAA
CAATTTCAAGGCCCAATTGTCGGAATTTGCGGCGGCTATCAGTTGCTCGGCCAGCAAATTGATGATCCAGAGGCGGTTGA
GGGCATTGGTGGTAGCATGGCAGGCTTAGGCTTATTACCAATCACCACGATTTTTCAGCGCCACAAGCAAACGCGCCAAG
TTCAGGCGCTCAGCAATTTACCATGGGCCAAAGCTTACCCACTGGCTGGCTATGAAATTCATATGGGGCGAACTGAACTG
TTGGCTGATCAACCAGCCTTTAGCATTCAACAAGCTGAATCAACCCATGCTGATGGCTGCATGCGAGCTAATGGCAAGGT
TTGGGGCTGTTACATTCATGGCATTTTTGCGAATACAGAATTTCGCCAAGCTTGGTTGAGCAGACTTGGTTGGCAGGTTC
AGTCAGCGATTCAGCCAATCGATCCCTTTGAGCGGCTCGCCGACCATGTTGAAGCATGTTTGGAGCCAAATTTATTGACC
AAGTTGTTGGGGCAGGAGATCAGGGACTAG

Upstream 100 bases:

>100_bases
TGGTGCGCGATTGTAGCTCATTTGGTTTGCCGCAGTTTGTACGGATCGCCCCGCGCCAACCAGCGGCAAATCAACGCTTG
TTGAATGCTTGGAGAAGTTT

Downstream 100 bases:

>100_bases
TTATCAGGGGCTAGCGGTCAGAAGCCTCACGAATCCAGGATTGAGCACAATCCCCTGGTCGCTCGTCATTTGTTTTTTGT
AGAACCCAGCGGTGCAGAGA

Product: cobyric acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLAPVLMVVGTASSVGKSTLVSALCRIAARRGIRVAPFKAQNMSNNAAVTANGEEIARSIAVQAAAAKLTPSVQMNPILI
KPEGQRRSQIIVQGRPWQTLEAIDYWQRKQLLWEIVTNSLDQLRQAYDLVIAEGAGSPVELNLKAHDITNMRVATYAQAQ
TLLVGDIDVGGIFAAMLGTLMLLEPEERQLIAGLIVNRFRGDPDLFTDGIQILEQRSNKPVLGVVPWLPQLGLPEEDAVA
LERPDQTTNNAALTIGVIQLPAIANFDDFDPLAQEQGVAVRYINQPHELQHCQALILPGTKHTLAARQWLTEQGFDQAIQ
QFQGPIVGICGGYQLLGQQIDDPEAVEGIGGSMAGLGLLPITTIFQRHKQTRQVQALSNLPWAKAYPLAGYEIHMGRTEL
LADQPAFSIQQAESTHADGCMRANGKVWGCYIHGIFANTEFRQAWLSRLGWQVQSAIQPIDPFERLADHVEACLEPNLLT
KLLGQEIRD

Sequences:

>Translated_489_residues
MLAPVLMVVGTASSVGKSTLVSALCRIAARRGIRVAPFKAQNMSNNAAVTANGEEIARSIAVQAAAAKLTPSVQMNPILI
KPEGQRRSQIIVQGRPWQTLEAIDYWQRKQLLWEIVTNSLDQLRQAYDLVIAEGAGSPVELNLKAHDITNMRVATYAQAQ
TLLVGDIDVGGIFAAMLGTLMLLEPEERQLIAGLIVNRFRGDPDLFTDGIQILEQRSNKPVLGVVPWLPQLGLPEEDAVA
LERPDQTTNNAALTIGVIQLPAIANFDDFDPLAQEQGVAVRYINQPHELQHCQALILPGTKHTLAARQWLTEQGFDQAIQ
QFQGPIVGICGGYQLLGQQIDDPEAVEGIGGSMAGLGLLPITTIFQRHKQTRQVQALSNLPWAKAYPLAGYEIHMGRTEL
LADQPAFSIQQAESTHADGCMRANGKVWGCYIHGIFANTEFRQAWLSRLGWQVQSAIQPIDPFERLADHVEACLEPNLLT
KLLGQEIRD
>Mature_489_residues
MLAPVLMVVGTASSVGKSTLVSALCRIAARRGIRVAPFKAQNMSNNAAVTANGEEIARSIAVQAAAAKLTPSVQMNPILI
KPEGQRRSQIIVQGRPWQTLEAIDYWQRKQLLWEIVTNSLDQLRQAYDLVIAEGAGSPVELNLKAHDITNMRVATYAQAQ
TLLVGDIDVGGIFAAMLGTLMLLEPEERQLIAGLIVNRFRGDPDLFTDGIQILEQRSNKPVLGVVPWLPQLGLPEEDAVA
LERPDQTTNNAALTIGVIQLPAIANFDDFDPLAQEQGVAVRYINQPHELQHCQALILPGTKHTLAARQWLTEQGFDQAIQ
QFQGPIVGICGGYQLLGQQIDDPEAVEGIGGSMAGLGLLPITTIFQRHKQTRQVQALSNLPWAKAYPLAGYEIHMGRTEL
LADQPAFSIQQAESTHADGCMRANGKVWGCYIHGIFANTEFRQAWLSRLGWQVQSAIQPIDPFERLADHVEACLEPNLLT
KLLGQEIRD

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_HERA2 (A9AZZ2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001543827.1
- ProteinModelPortal:   A9AZZ2
- SMR:   A9AZZ2
- GeneID:   5732955
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_1051
- HOGENOM:   HBG302271
- OMA:   RGDIANM
- ProtClustDB:   PRK00784
- BioCyc:   HAUR316274:HAUR_1051-MONOMER
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: NA

Molecular weight: Translated: 53563; Mature: 53563

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS51274 GATASE_COBBQ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 330-330 ACT_SITE 433-433

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPVLMVVGTASSVGKSTLVSALCRIAARRGIRVAPFKAQNMSNNAAVTANGEEIARSI
CCCCEEEEEECCHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEECHHHHHHHH
AVQAAAAKLTPSVQMNPILIKPEGQRRSQIIVQGRPWQTLEAIDYWQRKQLLWEIVTNSL
HHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DQLRQAYDLVIAEGAGSPVELNLKAHDITNMRVATYAQAQTLLVGDIDVGGIFAAMLGTL
HHHHHHHHEEEECCCCCCEEEEEEECCCCCCEEEEHHCCCEEEEECCCHHHHHHHHHHHH
MLLEPEERQLIAGLIVNRFRGDPDLFTDGIQILEQRSNKPVLGVVPWLPQLGLPEEDAVA
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEE
LERPDQTTNNAALTIGVIQLPAIANFDDFDPLAQEQGVAVRYINQPHELQHCQALILPGT
EECCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCCEEEECCCCHHHHHCEEEECCCC
KHTLAARQWLTEQGFDQAIQQFQGPIVGICGGYQLLGQQIDDPEAVEGIGGSMAGLGLLP
CHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHCCCCCCHHHHHHCCCCHHCCHHHH
ITTIFQRHKQTRQVQALSNLPWAKAYPLAGYEIHMGRTELLADQPAFSIQQAESTHADGC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHCCCCCCHHHHCCCCCCCCE
MRANGKVWGCYIHGIFANTEFRQAWLSRLGWQVQSAIQPIDPFERLADHVEACLEPNLLT
EECCCCEEEEEEEEEECCCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCHHHH
KLLGQEIRD
HHHHHHHCC
>Mature Secondary Structure
MLAPVLMVVGTASSVGKSTLVSALCRIAARRGIRVAPFKAQNMSNNAAVTANGEEIARSI
CCCCEEEEEECCHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEECHHHHHHHH
AVQAAAAKLTPSVQMNPILIKPEGQRRSQIIVQGRPWQTLEAIDYWQRKQLLWEIVTNSL
HHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DQLRQAYDLVIAEGAGSPVELNLKAHDITNMRVATYAQAQTLLVGDIDVGGIFAAMLGTL
HHHHHHHHEEEECCCCCCEEEEEEECCCCCCEEEEHHCCCEEEEECCCHHHHHHHHHHHH
MLLEPEERQLIAGLIVNRFRGDPDLFTDGIQILEQRSNKPVLGVVPWLPQLGLPEEDAVA
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEE
LERPDQTTNNAALTIGVIQLPAIANFDDFDPLAQEQGVAVRYINQPHELQHCQALILPGT
EECCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCCEEEECCCCHHHHHCEEEECCCC
KHTLAARQWLTEQGFDQAIQQFQGPIVGICGGYQLLGQQIDDPEAVEGIGGSMAGLGLLP
CHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHCCCCCCHHHHHHCCCCHHCCHHHH
ITTIFQRHKQTRQVQALSNLPWAKAYPLAGYEIHMGRTELLADQPAFSIQQAESTHADGC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHCCCCCCHHHHCCCCCCCCE
MRANGKVWGCYIHGIFANTEFRQAWLSRLGWQVQSAIQPIDPFERLADHVEACLEPNLLT
EECCCCEEEEEEEEEECCCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCHHHH
KLLGQEIRD
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA