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The map label for this gene is yggV [C]

Identifier: 159897479

GI number: 159897479

Start: 1090605

End: 1091204

Strand: Reverse

Name: yggV [C]

Synonym: Haur_0950

Alternate gene names: 159897479

Gene position: 1091204-1090605 (Counterclockwise)

Preceding gene: 159897480

Following gene: 159897476

Centisome position: 17.19

GC content: 51.17

Gene sequence:

>600_bases
ATGCAAAAGCTATTAATTGGTTCAAATAATGCCCATAAAGTCGGTGAACTGCGGGCAATTTTCAGTGGCTTGCCCTTTGA
ATTGCTAACCTTGGCCGATGCAGGCATCGATTATGAGGTTGAGGAAACGGGCACAACCTTTGTTGAAAATGCCCGTTTGA
AGGCCGAAACCTATGCCCAAATCAGTGGCTTGCCAACCTTGGCCGACGATTCAGGGCTGGAAGTCGCAGCCCTTGATGGC
AAACCTGGCATCTACACCGCCCGCTGGGCCTTGCCCGACCTAAATAACCCACATCGGGCTTACGCTCGGGTACTAGAAGA
ACTCAAAGGCAAGCCATTCCACGACCGAATTGCCCGTTTCGTCTGTGTAATTGCAATTGCTTGGCCCGGCCAACCAACCG
AGGTGGTTGAGGGTATTCTGCCTGGGGTAATTGCCGAGGAGCCTCGCGGTGTTGGTGGTTTTGGCTATGATCCGGTGTTT
TACCTTTTGGATTATGATAAGCATTTGGCAGAGCTTGACCCTGAGGAAAAAAACCGCATCAGCCATCGCGGCCAAGCCTG
TGCACTTGCACGTGAGGTTTTGGAGCTTTTAGCCAAATAA

Upstream 100 bases:

>100_bases
CCGATTGGGTTGCACCTTCGGCGCGTTTCGGCGGAGTCGCCGTCGCGGTGCATCGTTATGTCTTACAACATCAAAATGTC
CGTTCCTAGGGTAAGGATGT

Downstream 100 bases:

>100_bases
GCTTTTGATCCACGAAGGGCACGAAGAGCACGAAAAATTCTGTTTCGTGTACTTTGTGCCCTTTATTTTCAATTCCGCAC
TTCTGCTTTAAGCACAAAAC

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MQKLLIGSNNAHKVGELRAIFSGLPFELLTLADAGIDYEVEETGTTFVENARLKAETYAQISGLPTLADDSGLEVAALDG
KPGIYTARWALPDLNNPHRAYARVLEELKGKPFHDRIARFVCVIAIAWPGQPTEVVEGILPGVIAEEPRGVGGFGYDPVF
YLLDYDKHLAELDPEEKNRISHRGQACALAREVLELLAK

Sequences:

>Translated_199_residues
MQKLLIGSNNAHKVGELRAIFSGLPFELLTLADAGIDYEVEETGTTFVENARLKAETYAQISGLPTLADDSGLEVAALDG
KPGIYTARWALPDLNNPHRAYARVLEELKGKPFHDRIARFVCVIAIAWPGQPTEVVEGILPGVIAEEPRGVGGFGYDPVF
YLLDYDKHLAELDPEEKNRISHRGQACALAREVLELLAK
>Mature_199_residues
MQKLLIGSNNAHKVGELRAIFSGLPFELLTLADAGIDYEVEETGTTFVENARLKAETYAQISGLPTLADDSGLEVAALDG
KPGIYTARWALPDLNNPHRAYARVLEELKGKPFHDRIARFVCVIAIAWPGQPTEVVEGILPGVIAEEPRGVGGFGYDPVF
YLLDYDKHLAELDPEEKNRISHRGQACALAREVLELLAK

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=44.8979591836735, Blast_Score=154, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920712, Length=190, Percent_Identity=35.7894736842105, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21808; Mature: 21808

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLLIGSNNAHKVGELRAIFSGLPFELLTLADAGIDYEVEETGTTFVENARLKAETYAQ
CCCEEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCHHHHCCCHHHHHHHH
ISGLPTLADDSGLEVAALDGKPGIYTARWALPDLNNPHRAYARVLEELKGKPFHDRIARF
HCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
VCVIAIAWPGQPTEVVEGILPGVIAEEPRGVGGFGYDPVFYLLDYDKHLAELDPEEKNRI
HHHHEEECCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEECCHHHHHHCCCHHHHHH
SHRGQACALAREVLELLAK
HHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKLLIGSNNAHKVGELRAIFSGLPFELLTLADAGIDYEVEETGTTFVENARLKAETYAQ
CCCEEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCHHHHCCCHHHHHHHH
ISGLPTLADDSGLEVAALDGKPGIYTARWALPDLNNPHRAYARVLEELKGKPFHDRIARF
HCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
VCVIAIAWPGQPTEVVEGILPGVIAEEPRGVGGFGYDPVFYLLDYDKHLAELDPEEKNRI
HHHHEEECCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEECCHHHHHHCCCHHHHHH
SHRGQACALAREVLELLAK
HHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA