Click here to switch to the map view.

The map label for this gene is aiiA [H]

Identifier: 159897432

GI number: 159897432

Start: 1035371

End: 1036078

Strand: Reverse

Name: aiiA [H]

Synonym: Haur_0903

Alternate gene names: 159897432

Gene position: 1036078-1035371 (Counterclockwise)

Preceding gene: 159897433

Following gene: 159897431

Centisome position: 16.32

GC content: 50.71

Gene sequence:

>708_bases
ATGATGAGCCAACAAATGCCCCAGCGTTTATATTTGATGCAGGTTGGCACGATGCCAGAATATGCGATTCCGATCGTCTG
CTATCTGGTACAAACTGGCGATGGCAAGAATATTCTGATCGATACTGGGCTACCAGAGGTGATTCCAGCAGAAGGCGCGG
ATTTCGAAAATGGGCAGGATGTGGTCGTGCAGTTGGCCAATCTTGGTTTAACCCCAGACGATATTGATACGATCATTTCG
ACCCATTATGATTTTGATCACGCAGGCCGACATGGATTATTCACCAAAGCAACCTACATTGTGCAGCGCGTTCATCATCT
GGATGCGGCGAGCAACCCACGCTTTGCCGCCAACCGCCCGCAATGGGATCAACCAAGCGAGCGAATTCAGCTCATCGATG
GTGATAGCCAACTGCTGCCTGGGTTGGAACTGATTGAAACGAGCGGACACGTGCCAGGCCATCAATCGGTGCTGGTGCGG
CTACCCAAAACGGGGCCAGTTTTATTGCCAATTGATGCAGTACCTTTCGCAACTGGCTTTACTCGTGAGCAGCCAGCCGC
TGATAACAACCCCGATGCCGAGGCGACCCACGCCAGCACAATTAAATTGCTTGATCTGGTTGAACGAGAGCAGATTAAAC
TGGTGATTTTTGGTCACGACAATGAGCAGTGGCAAACGCTCAAACAAGCCCCAGCCTTTTACGATTAA

Upstream 100 bases:

>100_bases
AATTCGCTTGCTCAAGACCACGCTTTGGGATTGACAAACAATAGAACATTTGGTCTAATTTGAATAGAATTACGATTGAC
CTATGTTCGAAAAGGAAACG

Downstream 100 bases:

>100_bases
ACGCCAAAATCCTCGATCTGTCATTGCAAGCTCCGTCAAGCATGATAGAGCTTGCTCATACTACCTCAATCGACTATTAC
TCCCCACAACGCTTTGATAA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: AHL-lactonase AiiA [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MMSQQMPQRLYLMQVGTMPEYAIPIVCYLVQTGDGKNILIDTGLPEVIPAEGADFENGQDVVVQLANLGLTPDDIDTIIS
THYDFDHAGRHGLFTKATYIVQRVHHLDAASNPRFAANRPQWDQPSERIQLIDGDSQLLPGLELIETSGHVPGHQSVLVR
LPKTGPVLLPIDAVPFATGFTREQPAADNNPDAEATHASTIKLLDLVEREQIKLVIFGHDNEQWQTLKQAPAFYD

Sequences:

>Translated_235_residues
MMSQQMPQRLYLMQVGTMPEYAIPIVCYLVQTGDGKNILIDTGLPEVIPAEGADFENGQDVVVQLANLGLTPDDIDTIIS
THYDFDHAGRHGLFTKATYIVQRVHHLDAASNPRFAANRPQWDQPSERIQLIDGDSQLLPGLELIETSGHVPGHQSVLVR
LPKTGPVLLPIDAVPFATGFTREQPAADNNPDAEATHASTIKLLDLVEREQIKLVIFGHDNEQWQTLKQAPAFYD
>Mature_235_residues
MMSQQMPQRLYLMQVGTMPEYAIPIVCYLVQTGDGKNILIDTGLPEVIPAEGADFENGQDVVVQLANLGLTPDDIDTIIS
THYDFDHAGRHGLFTKATYIVQRVHHLDAASNPRFAANRPQWDQPSERIQLIDGDSQLLPGLELIETSGHVPGHQSVLVR
LPKTGPVLLPIDAVPFATGFTREQPAADNNPDAEATHASTIKLLDLVEREQIKLVIFGHDNEQWQTLKQAPAFYD

Specific function: Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long- chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.1.81 [H]

Molecular weight: Translated: 26008; Mature: 26008

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSQQMPQRLYLMQVGTMPEYAIPIVCYLVQTGDGKNILIDTGLPEVIPAEGADFENGQD
CCCCHHHHHEEEEEECCCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHH
VVVQLANLGLTPDDIDTIISTHYDFDHAGRHGLFTKATYIVQRVHHLDAASNPRFAANRP
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
QWDQPSERIQLIDGDSQLLPGLELIETSGHVPGHQSVLVRLPKTGPVLLPIDAVPFATGF
CCCCCCCEEEEECCCCCCCCCHHEECCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCC
TREQPAADNNPDAEATHASTIKLLDLVEREQIKLVIFGHDNEQWQTLKQAPAFYD
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MMSQQMPQRLYLMQVGTMPEYAIPIVCYLVQTGDGKNILIDTGLPEVIPAEGADFENGQD
CCCCHHHHHEEEEEECCCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHH
VVVQLANLGLTPDDIDTIISTHYDFDHAGRHGLFTKATYIVQRVHHLDAASNPRFAANRP
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
QWDQPSERIQLIDGDSQLLPGLELIETSGHVPGHQSVLVRLPKTGPVLLPIDAVPFATGF
CCCCCCCEEEEECCCCCCCCCHHEECCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCC
TREQPAADNNPDAEATHASTIKLLDLVEREQIKLVIFGHDNEQWQTLKQAPAFYD
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11916693; 12147491 [H]