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The map label for this gene is cat2 [H]

Identifier: 159897338

GI number: 159897338

Start: 915957

End: 917243

Strand: Reverse

Name: cat2 [H]

Synonym: Haur_0809

Alternate gene names: 159897338

Gene position: 917243-915957 (Counterclockwise)

Preceding gene: 159897340

Following gene: 159897336

Centisome position: 14.45

GC content: 51.52

Gene sequence:

>1287_bases
ATGCGTTACGTTTCAGCGAACGAAGCTGTTCAAGCGATTAAATCACACGATCGTGTGTTTATTCATAGTGTTGCCGCAGC
ACCTCAACAATTAATTGCGGCTTTGGTTGCTCGCGCCGATGAATTACGCAGCGTCGAATTGGTGCATATTCATACCGAAG
GGCCAGCACCATATACCGATCCCAAATATCGCGAAAGTTTTCATACCCGCGCGTTATTTATTGGCTCGAATATTCGGAGC
GCCGTGGTAACTGGTGAAGCTGATTATGTTCCGGTCTTTTTGAGCGAAGTTCCAGGCTTGTTCCGGCGGGGAATTTTGCC
GCTTGATATGGCATTAATTCAAGTTTCGCCACCTGATCAACATGGGTTTTGCTCGTTGGGCGTTTCGGTCGATGTCACCC
GAGCAGCCGTCGAAGTTGCTCAATGTGTAATTGCCCAAATCAACCCGCATATGCCCCGCACCCATGGCGATGGCCACATT
CATATCAATCGGATTAACTTTGCGGTTGAGGTCGATGAGCCAATTTATGAACATGCGCCAGCCGTTTTGAGTGATGTTGA
ACGGGCGATTGGCCGCCATATTGCGGGCTTGGTCAGCGATGGCGCAACCTTGCAAATGGGTATCGGGGCGATTCCTGATG
CCGTGCTAGCTTCATTAACCACCCACAAAAATTTGGGCATTCACACCGAAATGTTTTCCGATGGGATTATCGATTTGGTT
GAACGCGGCATCATCAACGGACGCATGAAGAAAACCCACCCCGGCAAAATCGTTGGTGGTTTTATGATGGGCACGCGGCG
ATTGTATGATTTCGTCGATGATAACCCGCAGATCGCCATGCTCGACATCACCTACATCAACGATACCAGCGTGATTCGGC
GCAACCCCAATGTTACGGCAATCAACAGTGCGATTGAAGTGGATCTGACGGGCCAAGTCTGTGCTGATTCAATTGGCACG
TTCCAGTATTCAGGGGTGGGCGGCCAAATGGACTTTATGCGCGGAGCAGCGCTCTCCGAGGGCGGCAAGCCAATTATTGC
CCTGCCTTCAGCTACCCGTCGTGGCGAATCGCGGATTGTGCCAGTGCTGCACGAAGGCGCTAGCGTCGTGACCACTCGTG
CCCACGTTCAATATATCGTCACTGAATATGGCGTAGCTTATTTGTATGGCAAAACCTTGCGCGAACGCGCTAAAGCCTTG
ATCGATATTGCTCACCCTGACCATCGCGAAGCGCTCGAACGGGCCGCTTTAGAGCGGTTTCACGGCGAAGCCAGCCTGAA
ACATTAG

Upstream 100 bases:

>100_bases
TAACCCATTTCATGGCTCTTTTCACTTCGTGCTGGCAAGAAATCGGTCACAATAGAGATGTAGCCGAGGCTACACCAACC
AACGATTTAGGGGGCTTAGT

Downstream 100 bases:

>100_bases
TTAAAATCCCTCATCCCCGACCCCTCTCCCACTGCGGCGGGAGAAGGGGCGAACTTAACTGCGCACCACCAATTCTTTGG
TTCATCGGTAGATGTCTGTT

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MRYVSANEAVQAIKSHDRVFIHSVAAAPQQLIAALVARADELRSVELVHIHTEGPAPYTDPKYRESFHTRALFIGSNIRS
AVVTGEADYVPVFLSEVPGLFRRGILPLDMALIQVSPPDQHGFCSLGVSVDVTRAAVEVAQCVIAQINPHMPRTHGDGHI
HINRINFAVEVDEPIYEHAPAVLSDVERAIGRHIAGLVSDGATLQMGIGAIPDAVLASLTTHKNLGIHTEMFSDGIIDLV
ERGIINGRMKKTHPGKIVGGFMMGTRRLYDFVDDNPQIAMLDITYINDTSVIRRNPNVTAINSAIEVDLTGQVCADSIGT
FQYSGVGGQMDFMRGAALSEGGKPIIALPSATRRGESRIVPVLHEGASVVTTRAHVQYIVTEYGVAYLYGKTLRERAKAL
IDIAHPDHREALERAALERFHGEASLKH

Sequences:

>Translated_428_residues
MRYVSANEAVQAIKSHDRVFIHSVAAAPQQLIAALVARADELRSVELVHIHTEGPAPYTDPKYRESFHTRALFIGSNIRS
AVVTGEADYVPVFLSEVPGLFRRGILPLDMALIQVSPPDQHGFCSLGVSVDVTRAAVEVAQCVIAQINPHMPRTHGDGHI
HINRINFAVEVDEPIYEHAPAVLSDVERAIGRHIAGLVSDGATLQMGIGAIPDAVLASLTTHKNLGIHTEMFSDGIIDLV
ERGIINGRMKKTHPGKIVGGFMMGTRRLYDFVDDNPQIAMLDITYINDTSVIRRNPNVTAINSAIEVDLTGQVCADSIGT
FQYSGVGGQMDFMRGAALSEGGKPIIALPSATRRGESRIVPVLHEGASVVTTRAHVQYIVTEYGVAYLYGKTLRERAKAL
IDIAHPDHREALERAALERFHGEASLKH
>Mature_428_residues
MRYVSANEAVQAIKSHDRVFIHSVAAAPQQLIAALVARADELRSVELVHIHTEGPAPYTDPKYRESFHTRALFIGSNIRS
AVVTGEADYVPVFLSEVPGLFRRGILPLDMALIQVSPPDQHGFCSLGVSVDVTRAAVEVAQCVIAQINPHMPRTHGDGHI
HINRINFAVEVDEPIYEHAPAVLSDVERAIGRHIAGLVSDGATLQMGIGAIPDAVLASLTTHKNLGIHTEMFSDGIIDLV
ERGIINGRMKKTHPGKIVGGFMMGTRRLYDFVDDNPQIAMLDITYINDTSVIRRNPNVTAINSAIEVDLTGQVCADSIGT
FQYSGVGGQMDFMRGAALSEGGKPIIALPSATRRGESRIVPVLHEGASVVTTRAHVQYIVTEYGVAYLYGKTLRERAKAL
IDIAHPDHREALERAALERFHGEASLKH

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=475, Percent_Identity=24.6315789473684, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563853, Length=426, Percent_Identity=51.6431924882629, Blast_Score=450, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17538151, Length=428, Percent_Identity=49.0654205607477, Blast_Score=411, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6319456, Length=242, Percent_Identity=28.9256198347107, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358615, Length=421, Percent_Identity=53.4441805225653, Blast_Score=468, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46553; Mature: 46553

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVSANEAVQAIKSHDRVFIHSVAAAPQQLIAALVARADELRSVELVHIHTEGPAPYTD
CCCCCHHHHHHHHHHCCEEEEEHHHHCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
PKYRESFHTRALFIGSNIRSAVVTGEADYVPVFLSEVPGLFRRGILPLDMALIQVSPPDQ
CHHHHHHCCEEEEECCCCCEEEEECCCCCEEHHHHHCCHHHHCCCCCEEEEEEEECCCCC
HGFCSLGVSVDVTRAAVEVAQCVIAQINPHMPRTHGDGHIHINRINFAVEVDEPIYEHAP
CCEEEECCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCHHHHCC
AVLSDVERAIGRHIAGLVSDGATLQMGIGAIPDAVLASLTTHKNLGIHTEMFSDGIIDLV
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCEEHHHHHCHHHHHH
ERGIINGRMKKTHPGKIVGGFMMGTRRLYDFVDDNPQIAMLDITYINDTSVIRRNPNVTA
HHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEECCCEEE
INSAIEVDLTGQVCADSIGTFQYSGVGGQMDFMRGAALSEGGKPIIALPSATRRGESRIV
ECCEEEEEECCHHHHCCCCCEEECCCCCCHHHHHCCHHCCCCCEEEECCCCCCCCCCCEE
PVLHEGASVVTTRAHVQYIVTEYGVAYLYGKTLRERAKALIDIAHPDHREALERAALERF
EEEECCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
HGEASLKH
CCCCCCCC
>Mature Secondary Structure
MRYVSANEAVQAIKSHDRVFIHSVAAAPQQLIAALVARADELRSVELVHIHTEGPAPYTD
CCCCCHHHHHHHHHHCCEEEEEHHHHCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
PKYRESFHTRALFIGSNIRSAVVTGEADYVPVFLSEVPGLFRRGILPLDMALIQVSPPDQ
CHHHHHHCCEEEEECCCCCEEEEECCCCCEEHHHHHCCHHHHCCCCCEEEEEEEECCCCC
HGFCSLGVSVDVTRAAVEVAQCVIAQINPHMPRTHGDGHIHINRINFAVEVDEPIYEHAP
CCEEEECCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCHHHHCC
AVLSDVERAIGRHIAGLVSDGATLQMGIGAIPDAVLASLTTHKNLGIHTEMFSDGIIDLV
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCEEHHHHHCHHHHHH
ERGIINGRMKKTHPGKIVGGFMMGTRRLYDFVDDNPQIAMLDITYINDTSVIRRNPNVTA
HHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEECCCEEE
INSAIEVDLTGQVCADSIGTFQYSGVGGQMDFMRGAALSEGGKPIIALPSATRRGESRIV
ECCEEEEEECCHHHHCCCCCEEECCCCCCHHHHHCCHHCCCCCEEEECCCCCCCCCCCEE
PVLHEGASVVTTRAHVQYIVTEYGVAYLYGKTLRERAKALIDIAHPDHREALERAALERF
EEEECCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
HGEASLKH
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]