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The map label for this gene is holB [H]

Identifier: 159897320

GI number: 159897320

Start: 893982

End: 895004

Strand: Reverse

Name: holB [H]

Synonym: Haur_0791

Alternate gene names: 159897320

Gene position: 895004-893982 (Counterclockwise)

Preceding gene: 159897326

Following gene: 159897317

Centisome position: 14.1

GC content: 52.1

Gene sequence:

>1023_bases
GTGGGAGCATGGAATATCATCGGAAATGAGTGGGCAGTCGAATTATTACGCTTGGCAATTGCCCGTAATGCAGCCAGCCA
TGCCTATTTGCTGACAGGTTTACCCAACATTGGCAAAGCGACGCTTGCCTTGCGCATGGCTCAAGCGCTCAACTGCGAAG
CCAATAATGGTGATGTTTGTGGCAACTGCCGAGCTTGTAAGCGGATTGCTAAAGGCAATTTTCCTGATGTGCGGATTGTG
GGCTTGGCTGAACAGGCCGCCCAACAAAAGGCCAGCGAAAGCGTCAAAACCCGTTTGGGTATCGACACCGTGCGCGAATG
GCAGGCTGATATTGCCCTACGGCCTTACGAAGGGCGACGGCGGGTCTTTATTATGCACGATGCTGAAACCATGACCGAAC
AAGCCGCCAACGCTTTGCTCAAAACGCTTGAAGAGCCACCACCGTTTGCCACCTTGATTTTGGTGGCCAATAGTGCTGGC
GATTTGTTGCCGACAATCACCTCACGTTGCCATGTACTCAAATTACGCCCAGTGCCACGCCAACAAGTGACCCAAGCATT
AATCGAACACTGGCAGATTGCCCCCGATGATGCGGCGATTGTGGCTGCATGGAGCGCAGGTCGCATCGGCTGGGCCGCAG
CAGTTGCCCAATCGCCCGACTTGTTGCAAGCTCGCGCCGAACAACTTGAGAGTTTGATCGAGTTGCCAAGCAAACCGCTG
GTTGAGCGCTTCAAATGGGCAGAAGGCTGGAGCAAAGCCAATCGTGAGCGTGATGAGCTGTTTGCCATGCTTGAATTATG
GCAAGTTTGGTGGCGCGATGTGTTATTGATTGCCGCTGGCACGCAGCAAGGCCTGATTAATATTGATCGAGTTGAAGATT
TACAGGCGTTATCACGCTTGCCATTAACGGCAATTCATAAAACGCTCAAGGGCATTAACGATGCAGTAACCCAAATTCGC
GAGAATGTTAGCCCGCAATTGGCTTTAGAAGGCGTGTTGCTGAATTTAGCTGGGGCAAAGTAG

Upstream 100 bases:

>100_bases
GGCATCTATTTACCTCACATTCAGCTATTTGGTACTAGGTTATTTTCTTGGTATCATGGCTCAAATAGATCAATCGTTGG
ATGGATTGGAGCGTACAGCG

Downstream 100 bases:

>100_bases
CAACGAGGGATCAGGAGTCAGTCGTTAGGGATCAGTAAAGGTTTTTTAGCCACAGATTGGCACAGATTATCCAGATGAGA
TTCCTGCTTAGCCAAGGCTT

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGAWNIIGNEWAVELLRLAIARNAASHAYLLTGLPNIGKATLALRMAQALNCEANNGDVCGNCRACKRIAKGNFPDVRIV
GLAEQAAQQKASESVKTRLGIDTVREWQADIALRPYEGRRRVFIMHDAETMTEQAANALLKTLEEPPPFATLILVANSAG
DLLPTITSRCHVLKLRPVPRQQVTQALIEHWQIAPDDAAIVAAWSAGRIGWAAAVAQSPDLLQARAEQLESLIELPSKPL
VERFKWAEGWSKANRERDELFAMLELWQVWWRDVLLIAAGTQQGLINIDRVEDLQALSRLPLTAIHKTLKGINDAVTQIR
ENVSPQLALEGVLLNLAGAK

Sequences:

>Translated_340_residues
MGAWNIIGNEWAVELLRLAIARNAASHAYLLTGLPNIGKATLALRMAQALNCEANNGDVCGNCRACKRIAKGNFPDVRIV
GLAEQAAQQKASESVKTRLGIDTVREWQADIALRPYEGRRRVFIMHDAETMTEQAANALLKTLEEPPPFATLILVANSAG
DLLPTITSRCHVLKLRPVPRQQVTQALIEHWQIAPDDAAIVAAWSAGRIGWAAAVAQSPDLLQARAEQLESLIELPSKPL
VERFKWAEGWSKANRERDELFAMLELWQVWWRDVLLIAAGTQQGLINIDRVEDLQALSRLPLTAIHKTLKGINDAVTQIR
ENVSPQLALEGVLLNLAGAK
>Mature_339_residues
GAWNIIGNEWAVELLRLAIARNAASHAYLLTGLPNIGKATLALRMAQALNCEANNGDVCGNCRACKRIAKGNFPDVRIVG
LAEQAAQQKASESVKTRLGIDTVREWQADIALRPYEGRRRVFIMHDAETMTEQAANALLKTLEEPPPFATLILVANSAGD
LLPTITSRCHVLKLRPVPRQQVTQALIEHWQIAPDDAAIVAAWSAGRIGWAAAVAQSPDLLQARAEQLESLIELPSKPLV
ERFKWAEGWSKANRERDELFAMLELWQVWWRDVLLIAAGTQQGLINIDRVEDLQALSRLPLTAIHKTLKGINDAVTQIRE
NVSPQLALEGVLLNLAGAK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=187, Percent_Identity=28.8770053475936, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787341, Length=215, Percent_Identity=33.4883720930233, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37421; Mature: 37289

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAWNIIGNEWAVELLRLAIARNAASHAYLLTGLPNIGKATLALRMAQALNCEANNGDVC
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
GNCRACKRIAKGNFPDVRIVGLAEQAAQQKASESVKTRLGIDTVREWQADIALRPYEGRR
CCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHHCCEECCCCCCE
RVFIMHDAETMTEQAANALLKTLEEPPPFATLILVANSAGDLLPTITSRCHVLKLRPVPR
EEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCCEEEEECCCCH
QQVTQALIEHWQIAPDDAAIVAAWSAGRIGWAAAVAQSPDLLQARAEQLESLIELPSKPL
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHH
VERFKWAEGWSKANRERDELFAMLELWQVWWRDVLLIAAGTQQGLINIDRVEDLQALSRL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEHHHHHHHHHHHHC
PLTAIHKTLKGINDAVTQIRENVSPQLALEGVLLNLAGAK
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GAWNIIGNEWAVELLRLAIARNAASHAYLLTGLPNIGKATLALRMAQALNCEANNGDVC
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
GNCRACKRIAKGNFPDVRIVGLAEQAAQQKASESVKTRLGIDTVREWQADIALRPYEGRR
CCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHHCCEECCCCCCE
RVFIMHDAETMTEQAANALLKTLEEPPPFATLILVANSAGDLLPTITSRCHVLKLRPVPR
EEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCCEEEEECCCCH
QQVTQALIEHWQIAPDDAAIVAAWSAGRIGWAAAVAQSPDLLQARAEQLESLIELPSKPL
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHH
VERFKWAEGWSKANRERDELFAMLELWQVWWRDVLLIAAGTQQGLINIDRVEDLQALSRL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEHHHHHHHHHHHHC
PLTAIHKTLKGINDAVTQIRENVSPQLALEGVLLNLAGAK
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]