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The map label for this gene is uhpB [C]

Identifier: 159897131

GI number: 159897131

Start: 691823

End: 693577

Strand: Direct

Name: uhpB [C]

Synonym: Haur_0602

Alternate gene names: 159897131

Gene position: 691823-693577 (Clockwise)

Preceding gene: 159897130

Following gene: 159897132

Centisome position: 10.9

GC content: 51.4

Gene sequence:

>1755_bases
ATGTCTATCTCCGTCCCACGCATTACACCACGACTATTAATGTCCGGTGATCCATTATTTAGCTTGGTGCGGTTGATTAG
CCTTGGCTTGATTTTGGTCGTCGGCGCTCGCATCGATCAACACACGGTTATTCCGCCAACCACCCCATTTGGCCTAATTT
GGTGGGCCTATGCGATCTATGGTTTAGTGATGGCTGGCTCGGCTTTTGTGCCCCGCTTTCGCAACTTGCCCTCGTGGATC
TTTATTGTTGATTTTGGCTTTATTGCGCTCTTTGCCTTGTTTAGCGGTCTGCCCCCCGCCTTGTTGGTAGCGTTGATTAT
GTTGCCAACTGTGTGGGCTTCAACCAATCGTTCGCCTGCCCAAGCAGTTGGTACGGGTGTGGGCGCAGCGATTGTCTATG
CTGGCATTACGCTATATCGGCGCTTTGGCGATGCTGGCAATGTTGGCAGCGAAGAGATGTTTGTTAGCATTGCAGTCAAC
TGTACAGCTTTGATTTTAGTTTCGTGGTTGGTCAGCACGCTTTCTGGTCAGTCCAGCGAGATCAATCGCGAACATGTGAT
TGCCGCACGGCGTGATGTCGATAGTGCTCAGCGTGATGCCGAAGCGTATCGCGACCGCATGCGAGCACTCTACGAAGTTG
CCTATAAACTTAGTACTACCATGAATTTTCAAACGGTGCTTGATGCCACCGTGACCGAATCGATTCGTTTGATCAATGGC
CGCAGTAGCGTGGTGCTGTTACCAACTGGCGAGCCAGATGAATTGTATGTTGCTGCTGGCGTTGGAGTTGGCTCTGGTGA
TCTCAATTTGCGGATTGCGATTGAGCCAACTGGAATTATGGCCTCGATTCTGGCCTCAGGCACGCCGCGCATTTTGAACG
ATTTGCGCCAATCACATGCCTTGAGCAGCGTACCATCGATGCAAAACTGTGCGTGTGTTTGTTGTGTGCCGCTGAGCGCA
GGCCGCCGCAACTATGGCATCGTGGTCGTCGGGGTTGATCGTAACGAAATCAATGAAGATGAATTGGGTATGGTTTCGGC
CTTGGCCAATTACGCAATTATTGCCATGCTCAATGCCCAATTGGTTGGCGAATTACGCGATGAACGCACCAAACTGATTA
GCAAAGAAGAAGAAGTGCGCCAACAACTTGCCCGCGATTTGCACGATGGCCCCGCTCAATCAGTGGCCGCCATCACCATG
AATATTGAATTTGTCAAGCGTTTATTGGAGCGCGAACCAAGCCGCGTGATGCAAGAGCTGACCAAAATGGGCGAATTAGC
CCGCCGCACCACCTATGATATTCGCACGCTTTTGTTCGAGTTGCGCCCCTTGACTCTGGATAGCCAAGGCCTCGTTGCGA
CCCTGCGCGAATATGTAACCCGCTTCAAAGATGGCACGACCCAGGTAATCCTCGAAGAAACCGTCGGCGAGTTGCGGCTT
GATGCCAAACGTGAAGGCACCTTGTTCAATATTATTCAAGAAGCTAGCAACAATGCCATGAAACATGCCCAAGCCAAACA
CATCTGGATTCGGCTAACCCGCCAAGGCGATGAGTTGATGGCGACAGTGCAGGATGATGGCAAAGGCTTCGATTTGCAAG
CAGTTCGGGCTAACTACAGCAAACGTGGCTCGTTTGGCCTCTTAAATATTGATGAACGGGCACGCATGGTTGGCGGGAGT
GCCGAAATGACCTCAGCAGTTGGCGCTGGTACAACCGTTCGGGTTATTGTACCGCTTGATGCCAGTAGTATTTAG

Upstream 100 bases:

>100_bases
AAAATTCTCAAAGAGCAGCTCTACCAAGCTGCAATCGAGGGCGAACCACTGATTGACGGAATTTCCTTCTAAGATAGTTA
GTGCCGAGGAAGATTCAACC

Downstream 100 bases:

>100_bases
ATAATGAATCTACTGACCCCGCGACGAGTGCTCGTCGCGGGGTTTTATAGTTAATTGCCTTCATCCCAACCCCGCTCTCA
CTGCGGCGGGCGAGGGTAAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSISVPRITPRLLMSGDPLFSLVRLISLGLILVVGARIDQHTVIPPTTPFGLIWWAYAIYGLVMAGSAFVPRFRNLPSWI
FIVDFGFIALFALFSGLPPALLVALIMLPTVWASTNRSPAQAVGTGVGAAIVYAGITLYRRFGDAGNVGSEEMFVSIAVN
CTALILVSWLVSTLSGQSSEINREHVIAARRDVDSAQRDAEAYRDRMRALYEVAYKLSTTMNFQTVLDATVTESIRLING
RSSVVLLPTGEPDELYVAAGVGVGSGDLNLRIAIEPTGIMASILASGTPRILNDLRQSHALSSVPSMQNCACVCCVPLSA
GRRNYGIVVVGVDRNEINEDELGMVSALANYAIIAMLNAQLVGELRDERTKLISKEEEVRQQLARDLHDGPAQSVAAITM
NIEFVKRLLEREPSRVMQELTKMGELARRTTYDIRTLLFELRPLTLDSQGLVATLREYVTRFKDGTTQVILEETVGELRL
DAKREGTLFNIIQEASNNAMKHAQAKHIWIRLTRQGDELMATVQDDGKGFDLQAVRANYSKRGSFGLLNIDERARMVGGS
AEMTSAVGAGTTVRVIVPLDASSI

Sequences:

>Translated_584_residues
MSISVPRITPRLLMSGDPLFSLVRLISLGLILVVGARIDQHTVIPPTTPFGLIWWAYAIYGLVMAGSAFVPRFRNLPSWI
FIVDFGFIALFALFSGLPPALLVALIMLPTVWASTNRSPAQAVGTGVGAAIVYAGITLYRRFGDAGNVGSEEMFVSIAVN
CTALILVSWLVSTLSGQSSEINREHVIAARRDVDSAQRDAEAYRDRMRALYEVAYKLSTTMNFQTVLDATVTESIRLING
RSSVVLLPTGEPDELYVAAGVGVGSGDLNLRIAIEPTGIMASILASGTPRILNDLRQSHALSSVPSMQNCACVCCVPLSA
GRRNYGIVVVGVDRNEINEDELGMVSALANYAIIAMLNAQLVGELRDERTKLISKEEEVRQQLARDLHDGPAQSVAAITM
NIEFVKRLLEREPSRVMQELTKMGELARRTTYDIRTLLFELRPLTLDSQGLVATLREYVTRFKDGTTQVILEETVGELRL
DAKREGTLFNIIQEASNNAMKHAQAKHIWIRLTRQGDELMATVQDDGKGFDLQAVRANYSKRGSFGLLNIDERARMVGGS
AEMTSAVGAGTTVRVIVPLDASSI
>Mature_583_residues
SISVPRITPRLLMSGDPLFSLVRLISLGLILVVGARIDQHTVIPPTTPFGLIWWAYAIYGLVMAGSAFVPRFRNLPSWIF
IVDFGFIALFALFSGLPPALLVALIMLPTVWASTNRSPAQAVGTGVGAAIVYAGITLYRRFGDAGNVGSEEMFVSIAVNC
TALILVSWLVSTLSGQSSEINREHVIAARRDVDSAQRDAEAYRDRMRALYEVAYKLSTTMNFQTVLDATVTESIRLINGR
SSVVLLPTGEPDELYVAAGVGVGSGDLNLRIAIEPTGIMASILASGTPRILNDLRQSHALSSVPSMQNCACVCCVPLSAG
RRNYGIVVVGVDRNEINEDELGMVSALANYAIIAMLNAQLVGELRDERTKLISKEEEVRQQLARDLHDGPAQSVAAITMN
IEFVKRLLEREPSRVMQELTKMGELARRTTYDIRTLLFELRPLTLDSQGLVATLREYVTRFKDGTTQVILEETVGELRLD
AKREGTLFNIIQEASNNAMKHAQAKHIWIRLTRQGDELMATVQDDGKGFDLQAVRANYSKRGSFGLLNIDERARMVGGSA
EMTSAVGAGTTVRVIVPLDASSI

Specific function: Member Of The Two-Component Regulatory System Uhpb/Uhpa Involved In The Regulation Of The Uptake Of Hexose Phosphates. Uhpb Functions As A Membrane-Associated Protein Kinase That Phosphorylates Uhpa In Response To Environmental Signals. [C]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=230, Percent_Identity=29.1304347826087, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788812, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787474, Length=264, Percent_Identity=26.1363636363636, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 63730; Mature: 63598

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISVPRITPRLLMSGDPLFSLVRLISLGLILVVGARIDQHTVIPPTTPFGLIWWAYAIY
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
GLVMAGSAFVPRFRNLPSWIFIVDFGFIALFALFSGLPPALLVALIMLPTVWASTNRSPA
HHHHCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
QAVGTGVGAAIVYAGITLYRRFGDAGNVGSEEMFVSIAVNCTALILVSWLVSTLSGQSSE
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCC
INREHVIAARRDVDSAQRDAEAYRDRMRALYEVAYKLSTTMNFQTVLDATVTESIRLING
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECC
RSSVVLLPTGEPDELYVAAGVGVGSGDLNLRIAIEPTGIMASILASGTPRILNDLRQSHA
CCCEEEEECCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHH
LSSVPSMQNCACVCCVPLSAGRRNYGIVVVGVDRNEINEDELGMVSALANYAIIAMLNAQ
HHCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LVGELRDERTKLISKEEEVRQQLARDLHDGPAQSVAAITMNIEFVKRLLEREPSRVMQEL
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCHHHHHHHH
TKMGELARRTTYDIRTLLFELRPLTLDSQGLVATLREYVTRFKDGTTQVILEETVGELRL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHEE
DAKREGTLFNIIQEASNNAMKHAQAKHIWIRLTRQGDELMATVQDDGKGFDLQAVRANYS
CCCCCCHHHHHHHHHCCHHHHHHHHCEEEEEEECCCCEEEEEEECCCCCCEEHHHHCCCC
KRGSFGLLNIDERARMVGGSAEMTSAVGAGTTVRVIVPLDASSI
CCCCEEEEEHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
SISVPRITPRLLMSGDPLFSLVRLISLGLILVVGARIDQHTVIPPTTPFGLIWWAYAIY
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
GLVMAGSAFVPRFRNLPSWIFIVDFGFIALFALFSGLPPALLVALIMLPTVWASTNRSPA
HHHHCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
QAVGTGVGAAIVYAGITLYRRFGDAGNVGSEEMFVSIAVNCTALILVSWLVSTLSGQSSE
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCC
INREHVIAARRDVDSAQRDAEAYRDRMRALYEVAYKLSTTMNFQTVLDATVTESIRLING
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECC
RSSVVLLPTGEPDELYVAAGVGVGSGDLNLRIAIEPTGIMASILASGTPRILNDLRQSHA
CCCEEEEECCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHH
LSSVPSMQNCACVCCVPLSAGRRNYGIVVVGVDRNEINEDELGMVSALANYAIIAMLNAQ
HHCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LVGELRDERTKLISKEEEVRQQLARDLHDGPAQSVAAITMNIEFVKRLLEREPSRVMQEL
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCHHHHHHHH
TKMGELARRTTYDIRTLLFELRPLTLDSQGLVATLREYVTRFKDGTTQVILEETVGELRL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHEE
DAKREGTLFNIIQEASNNAMKHAQAKHIWIRLTRQGDELMATVQDDGKGFDLQAVRANYS
CCCCCCHHHHHHHHHCCHHHHHHHHCEEEEEEECCCCEEEEEEECCCCCCEEHHHHCCCC
KRGSFGLLNIDERARMVGGSAEMTSAVGAGTTVRVIVPLDASSI
CCCCEEEEEHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8661927 [H]