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The map label for this gene is cpg2 [H]

Identifier: 159897024

GI number: 159897024

Start: 574177

End: 575307

Strand: Direct

Name: cpg2 [H]

Synonym: Haur_0492

Alternate gene names: 159897024

Gene position: 574177-575307 (Clockwise)

Preceding gene: 159897020

Following gene: 159897034

Centisome position: 9.05

GC content: 51.72

Gene sequence:

>1131_bases
ATGCCTCGTCAGCTTTTAACCTATGTTGATGCTTGCCTACCCGATCTGCTGGATGAAATGCGTCAATGGATCGAAATTGA
ATCGTTTACCCGTGATATTACGGCGGTTTCTTGGATGGTCAACGTGGTTGGCGAGCGTTTGAGTAAGCTTGGTGCAAGTG
TGCGCAAATATAATGGCAAGCCCCAAGCCGACCATTTGTTGGCAAGTTGGCCAGGCGAGGGCGAACCATTGCTAATTGTG
GGCCATGTTGATACCGTTTATCCGCCAGGCACGATTGATCAATTTCCGTTCCGCATCGATGGCGATGTGGTGCGTGGGCC
TGGAGTCAGCGATATGAAGGGCTGTATTTTGCTGACTTGCGCCGCCTTGCAAGCCTTACGCCACTTTAGCCGCTGGACCA
GCCGCCCCTTGAAATTTTTAATTACGACCGATGAAGAGATTGGTAGCCCAACCTCCCGACGGTATATTGAAGAACAGGCT
CGCGGTTGTCGCGCAGCCTTGATTATCGAATCAGCAGAAGAGGGTGGTTGGCTCAAAACATGGCGCAAAAGTGTCAGTAT
GTATGACTTAACAATTACTGGCAAGCCCTCGCATGCGGGGGTAGCCCCGGAGCTTGGCATTAGCGCGATTCACGAATTAA
GCTACCAAATTGGCCAGATTTTGCCCTTGGCGCGGCCTGAAATTGGCACAACGATCAATATTGGCAAAATTAATGGTGGT
ACTGCCACCAATGTTGTAGCCGCCGAGGCCCATTGCACGATCGATGTGCGGGCATTAAAAGTTGGCGAGGCGGAACGGGT
TGATCAAGCGCTGCATCAATTAGTGCCCCATTTGGCTGGCGCAAAATTAACTTTAGAAGGTGGCGTAAATCGCCCAGCCA
TGGAACAAACGCCTGCCACAATGGCATTATATGCTGCTGCCGAGCAAATTGCCAATCAATTGGATTTGCCGATTAAAGCT
AGTGGCACTGGCGGCGGTTCGGATGGCAATTTCACGTCGGCGATCGGTGTGCCAACCCTCGATGGGCTTGGTGGCTGGGG
CAGTGATTCGCATAGCTTCGATGAATGGCTTTCGATCAGCCAATTTGCCCCACGGGCTGCCTTGCTGGCTCGTTTGATTG
AGACATTGTAG

Upstream 100 bases:

>100_bases
CTATGCTGATGCAAGATAGGCCTGATTGCGGCGATTAAGTTGGTATAGGCGCTGGCTGCGGTACAATACAGCTACGACTG
CTTAGTGATGGAGGAAGCCC

Downstream 100 bases:

>100_bases
GCATTGGGGATCGGTTACTGGGGGTTGGGGATCGGAGCGAGGGATCTGGATTCAGGGAGTTCCAGCGTTGATTCCCCCTC
GCCCGCCCAGCGGGCGAGGG

Product: peptidase M20

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MPRQLLTYVDACLPDLLDEMRQWIEIESFTRDITAVSWMVNVVGERLSKLGASVRKYNGKPQADHLLASWPGEGEPLLIV
GHVDTVYPPGTIDQFPFRIDGDVVRGPGVSDMKGCILLTCAALQALRHFSRWTSRPLKFLITTDEEIGSPTSRRYIEEQA
RGCRAALIIESAEEGGWLKTWRKSVSMYDLTITGKPSHAGVAPELGISAIHELSYQIGQILPLARPEIGTTINIGKINGG
TATNVVAAEAHCTIDVRALKVGEAERVDQALHQLVPHLAGAKLTLEGGVNRPAMEQTPATMALYAAAEQIANQLDLPIKA
SGTGGGSDGNFTSAIGVPTLDGLGGWGSDSHSFDEWLSISQFAPRAALLARLIETL

Sequences:

>Translated_376_residues
MPRQLLTYVDACLPDLLDEMRQWIEIESFTRDITAVSWMVNVVGERLSKLGASVRKYNGKPQADHLLASWPGEGEPLLIV
GHVDTVYPPGTIDQFPFRIDGDVVRGPGVSDMKGCILLTCAALQALRHFSRWTSRPLKFLITTDEEIGSPTSRRYIEEQA
RGCRAALIIESAEEGGWLKTWRKSVSMYDLTITGKPSHAGVAPELGISAIHELSYQIGQILPLARPEIGTTINIGKINGG
TATNVVAAEAHCTIDVRALKVGEAERVDQALHQLVPHLAGAKLTLEGGVNRPAMEQTPATMALYAAAEQIANQLDLPIKA
SGTGGGSDGNFTSAIGVPTLDGLGGWGSDSHSFDEWLSISQFAPRAALLARLIETL
>Mature_375_residues
PRQLLTYVDACLPDLLDEMRQWIEIESFTRDITAVSWMVNVVGERLSKLGASVRKYNGKPQADHLLASWPGEGEPLLIVG
HVDTVYPPGTIDQFPFRIDGDVVRGPGVSDMKGCILLTCAALQALRHFSRWTSRPLKFLITTDEEIGSPTSRRYIEEQAR
GCRAALIIESAEEGGWLKTWRKSVSMYDLTITGKPSHAGVAPELGISAIHELSYQIGQILPLARPEIGTTINIGKINGGT
ATNVVAAEAHCTIDVRALKVGEAERVDQALHQLVPHLAGAKLTLEGGVNRPAMEQTPATMALYAAAEQIANQLDLPIKAS
GTGGGSDGNFTSAIGVPTLDGLGGWGSDSHSFDEWLSISQFAPRAALLARLIETL

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 40538; Mature: 40407

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRQLLTYVDACLPDLLDEMRQWIEIESFTRDITAVSWMVNVVGERLSKLGASVRKYNGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PQADHLLASWPGEGEPLLIVGHVDTVYPPGTIDQFPFRIDGDVVRGPGVSDMKGCILLTC
CCCCHHEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEECCCCCCCHHHHHHHHH
AALQALRHFSRWTSRPLKFLITTDEEIGSPTSRRYIEEQARGCRAALIIESAEEGGWLKT
HHHHHHHHHHHHHCCCEEEEEECCHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHH
WRKSVSMYDLTITGKPSHAGVAPELGISAIHELSYQIGQILPLARPEIGTTINIGKINGG
HHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
TATNVVAAEAHCTIDVRALKVGEAERVDQALHQLVPHLAGAKLTLEGGVNRPAMEQTPAT
CCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHH
MALYAAAEQIANQLDLPIKASGTGGGSDGNFTSAIGVPTLDGLGGWGSDSHSFDEWLSIS
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
QFAPRAALLARLIETL
HCCHHHHHHHHHHHHC
>Mature Secondary Structure 
PRQLLTYVDACLPDLLDEMRQWIEIESFTRDITAVSWMVNVVGERLSKLGASVRKYNGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PQADHLLASWPGEGEPLLIVGHVDTVYPPGTIDQFPFRIDGDVVRGPGVSDMKGCILLTC
CCCCHHEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEECCCCCCCHHHHHHHHH
AALQALRHFSRWTSRPLKFLITTDEEIGSPTSRRYIEEQARGCRAALIIESAEEGGWLKT
HHHHHHHHHHHHHCCCEEEEEECCHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHH
WRKSVSMYDLTITGKPSHAGVAPELGISAIHELSYQIGQILPLARPEIGTTINIGKINGG
HHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
TATNVVAAEAHCTIDVRALKVGEAERVDQALHQLVPHLAGAKLTLEGGVNRPAMEQTPAT
CCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHH
MALYAAAEQIANQLDLPIKASGTGGGSDGNFTSAIGVPTLDGLGGWGSDSHSFDEWLSIS
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
QFAPRAALLARLIETL
HCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]