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The map label for this gene is tkt [H]

Identifier: 159897019

GI number: 159897019

Start: 566338

End: 568341

Strand: Direct

Name: tkt [H]

Synonym: Haur_0487

Alternate gene names: 159897019

Gene position: 566338-568341 (Clockwise)

Preceding gene: 159897016

Following gene: 159897020

Centisome position: 8.92

GC content: 53.44

Gene sequence:

>2004_bases
GTGACTCAAGCACATACACTCGATGAACGGGCCATCAATACAATCCGCATGTTGTCGGTTGATGGTGTGCAAGCGGCTAA
TTCGGGCCACCCAGGTTTACCAATGGGGGCAGCGGCCATGGCTTATGTGCTCTGGACGCGCCACCTCAAACATAATCCGG
CTAATCCAGATTGGGCTGATCGCGACCGCTTTGTGCTGTCGGCGGGCCATGGCTCAATGCTGTTGTATAGTTTGTTGCAT
CTCACGGGCTATGATCTTTCGCTCGATGATTTGAAGAATTTCCGCCAATGGCATAGTAAAACCGCTGGTCACCCAGAATA
TGGTTATGCCGCCGGCATCGAAACCACAACTGGGCCACTTGGCCAAGGATTTGCCACGGGCGTGGGTATGGCGATTGCTG
CCCGTCACTTAGCAGGCACGTTCAATCAGCCTGAACTCGAAATCGTCAAGCATCATATTTATGCGATTGTCTCCGATGGC
GATTTGGAAGAGGGGATTAGCGCCGAAGCTGCTTCGTTGGCAGGTCACCTCAAATTGGGCGAACTTATCTATCTGTATGA
TGATAACGAAATTTCGATTGAAGGCGATACCTCAATTGCCTTTACCGAAGATGTGCCAGCCCGTTTCCGCGCCTATGGCT
GGCATGTCCAAGAGATCGACGGGCTTGATCCTGAGCAAGTTGATGCAGCCTTGCATGCTGCCAAAGCGGTGACCGATCAG
CCATCGTTGATTGTGGCTCACACCGTGATTGGCTTTGGCTCGCCCAATCGGGCTGGCACGGCCAAAGCTCACGGCTCGCC
GCTCGGCCCCGATGAAGTTAAATTGACCAAGGAAGCGCTTGGTTGGCCGCTCGAACCAACCTTCTACATTCCTGAAGAAG
TCTTGGCCCACTTCCGCCAAGCCTTGGATCATGGTGCGGCGGCAGAGCAAGCCTGGAACGAATTGCTCGAACGCTACACG
GCGGCGCATCCTGAAAAAGCTGCTGATTTCAAGCAACGCATGTCGGGTGAATTGCCAGCAGGTTGGGATAGTACCTTGCC
AGTTTGGCCAGCTGATGCCAAAGGCGTGGCAACCCGCAAATCATCAGAAACTGCCTTGAATGCCTTGGCCGAGCAAATTC
CAGCGCTCATTGGCGGCTCAGCTGATTTGGCCGAATCGACCTTTACCTTGATCGAGCATGCTCAATCGTTCCAAGCCGAT
ACGCCGCAAGGCCGCAATATGCACTGGGGGATTCGTGAGCATGCTATGGTTGCTGCCGTCAACGGGATGGCGTTGCATGG
CGGCACGATTCCTTACGGCGCAACCTTCTTGGTTTTCAGCGATTATTGCCGTGCCTCGATTCGCTTGGCAGCCTTGATGG
GCATTCGCACGATTCAAGTCTTTACTCACGATAGCATTGGGGTTGGCGAAGACGGCCCAACCCACCAACCAATCGAACAC
ATTCCATCGTTGCGGATTATCCCCAATTTGAATGTGATGCGGCCTGGTGATGCCAACGAAACCAGCCAAGCTTGGCGCGT
AGCAGTCAGCCATAAAGGCCCAACCTTGCTGGCCTTGACCCGCCAAAACTTACCAACGCTTGATCGCACCCGCTATGCCT
CGGCTGAGGGTGTGGCTCAAGGTGGCTATGTCTTGGCTGATAGCGCTGGTCAACCAGAATTAATCATCATTGCAACTGGC
TCGGAATTGCAACATGCCGTGGCGGCCTACGAGCAATTGAGTGGCGAAGGAGTCAAGGTACGGGTGGTCAGTATGCCATC
AACCTTGCTGTTCGACGCTCAGTCAGTGGAATATCGCGAGAGCGTACTGCCCAAGGCTGTGACCAAACGGATTGCGATTG
AAGCTGCGCATCCCGTGACCTGGTATAAATATGTTGGGACTGAGGGCGATATTATTGGGATTGATCACTTCGGTGCTTCA
GCGCCAATTAATATTTTGATGAAGGAATTTGGCTTTACCGCCGAAAACCTGATTGCTCGTGCCAAGGCCTTGTTGGCCAA
ATAA

Upstream 100 bases:

>100_bases
CAACCAATCAATTGCTTTTAGGAGTGTACCATAGAATGACAATGGATCGGCCTCTGCTATAATTGACAGTTGGAACTGAT
ACACCACCGCAGGAGGATTT

Downstream 100 bases:

>100_bases
TTAATCGATCGATCAAACGGATAACGCGAAGGACGAGTTGCTCGTGCTTCGCGTTATGCTGTGGAAAGGCAAATGATTAT
GAAAATTGCGGTCGGAACCG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MTQAHTLDERAINTIRMLSVDGVQAANSGHPGLPMGAAAMAYVLWTRHLKHNPANPDWADRDRFVLSAGHGSMLLYSLLH
LTGYDLSLDDLKNFRQWHSKTAGHPEYGYAAGIETTTGPLGQGFATGVGMAIAARHLAGTFNQPELEIVKHHIYAIVSDG
DLEEGISAEAASLAGHLKLGELIYLYDDNEISIEGDTSIAFTEDVPARFRAYGWHVQEIDGLDPEQVDAALHAAKAVTDQ
PSLIVAHTVIGFGSPNRAGTAKAHGSPLGPDEVKLTKEALGWPLEPTFYIPEEVLAHFRQALDHGAAAEQAWNELLERYT
AAHPEKAADFKQRMSGELPAGWDSTLPVWPADAKGVATRKSSETALNALAEQIPALIGGSADLAESTFTLIEHAQSFQAD
TPQGRNMHWGIREHAMVAAVNGMALHGGTIPYGATFLVFSDYCRASIRLAALMGIRTIQVFTHDSIGVGEDGPTHQPIEH
IPSLRIIPNLNVMRPGDANETSQAWRVAVSHKGPTLLALTRQNLPTLDRTRYASAEGVAQGGYVLADSAGQPELIIIATG
SELQHAVAAYEQLSGEGVKVRVVSMPSTLLFDAQSVEYRESVLPKAVTKRIAIEAAHPVTWYKYVGTEGDIIGIDHFGAS
APINILMKEFGFTAENLIARAKALLAK

Sequences:

>Translated_667_residues
MTQAHTLDERAINTIRMLSVDGVQAANSGHPGLPMGAAAMAYVLWTRHLKHNPANPDWADRDRFVLSAGHGSMLLYSLLH
LTGYDLSLDDLKNFRQWHSKTAGHPEYGYAAGIETTTGPLGQGFATGVGMAIAARHLAGTFNQPELEIVKHHIYAIVSDG
DLEEGISAEAASLAGHLKLGELIYLYDDNEISIEGDTSIAFTEDVPARFRAYGWHVQEIDGLDPEQVDAALHAAKAVTDQ
PSLIVAHTVIGFGSPNRAGTAKAHGSPLGPDEVKLTKEALGWPLEPTFYIPEEVLAHFRQALDHGAAAEQAWNELLERYT
AAHPEKAADFKQRMSGELPAGWDSTLPVWPADAKGVATRKSSETALNALAEQIPALIGGSADLAESTFTLIEHAQSFQAD
TPQGRNMHWGIREHAMVAAVNGMALHGGTIPYGATFLVFSDYCRASIRLAALMGIRTIQVFTHDSIGVGEDGPTHQPIEH
IPSLRIIPNLNVMRPGDANETSQAWRVAVSHKGPTLLALTRQNLPTLDRTRYASAEGVAQGGYVLADSAGQPELIIIATG
SELQHAVAAYEQLSGEGVKVRVVSMPSTLLFDAQSVEYRESVLPKAVTKRIAIEAAHPVTWYKYVGTEGDIIGIDHFGAS
APINILMKEFGFTAENLIARAKALLAK
>Mature_666_residues
TQAHTLDERAINTIRMLSVDGVQAANSGHPGLPMGAAAMAYVLWTRHLKHNPANPDWADRDRFVLSAGHGSMLLYSLLHL
TGYDLSLDDLKNFRQWHSKTAGHPEYGYAAGIETTTGPLGQGFATGVGMAIAARHLAGTFNQPELEIVKHHIYAIVSDGD
LEEGISAEAASLAGHLKLGELIYLYDDNEISIEGDTSIAFTEDVPARFRAYGWHVQEIDGLDPEQVDAALHAAKAVTDQP
SLIVAHTVIGFGSPNRAGTAKAHGSPLGPDEVKLTKEALGWPLEPTFYIPEEVLAHFRQALDHGAAAEQAWNELLERYTA
AHPEKAADFKQRMSGELPAGWDSTLPVWPADAKGVATRKSSETALNALAEQIPALIGGSADLAESTFTLIEHAQSFQADT
PQGRNMHWGIREHAMVAAVNGMALHGGTIPYGATFLVFSDYCRASIRLAALMGIRTIQVFTHDSIGVGEDGPTHQPIEHI
PSLRIIPNLNVMRPGDANETSQAWRVAVSHKGPTLLALTRQNLPTLDRTRYASAEGVAQGGYVLADSAGQPELIIIATGS
ELQHAVAAYEQLSGEGVKVRVVSMPSTLLFDAQSVEYRESVLPKAVTKRIAIEAAHPVTWYKYVGTEGDIIGIDHFGASA
PINILMKEFGFTAENLIARAKALLAK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=572, Percent_Identity=27.0979020979021, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI4507521, Length=572, Percent_Identity=27.0979020979021, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI133778974, Length=587, Percent_Identity=26.4054514480409, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI225637459, Length=586, Percent_Identity=22.0136518771331, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI225637463, Length=488, Percent_Identity=22.9508196721311, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI225637461, Length=488, Percent_Identity=22.9508196721311, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI48994911, Length=659, Percent_Identity=55.9939301972686, Blast_Score=736, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=659, Percent_Identity=55.3869499241275, Blast_Score=712, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=666, Percent_Identity=25.3753753753754, Blast_Score=182, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6325331, Length=676, Percent_Identity=47.9289940828402, Blast_Score=602, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6319593, Length=676, Percent_Identity=45.4142011834319, Blast_Score=568, Evalue=1e-163,
Organism=Drosophila melanogaster, GI45551847, Length=668, Percent_Identity=26.1976047904192, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI45550715, Length=668, Percent_Identity=26.1976047904192, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24645119, Length=640, Percent_Identity=25.9375, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24666278, Length=587, Percent_Identity=24.8722316865417, Blast_Score=146, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71828; Mature: 71697

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAHTLDERAINTIRMLSVDGVQAANSGHPGLPMGAAAMAYVLWTRHLKHNPANPDWAD
CCCCCCCHHHHHCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
RDRFVLSAGHGSMLLYSLLHLTGYDLSLDDLKNFRQWHSKTAGHPEYGYAAGIETTTGPL
CCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCC
GQGFATGVGMAIAARHLAGTFNQPELEIVKHHIYAIVSDGDLEEGISAEAASLAGHLKLG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEECCCHHHCCCHHHHHHHCCEEEC
ELIYLYDDNEISIEGDTSIAFTEDVPARFRAYGWHVQEIDGLDPEQVDAALHAAKAVTDQ
CEEEEEECCEEEEECCCEEEEECCCCHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHCCC
PSLIVAHTVIGFGSPNRAGTAKAHGSPLGPDEVKLTKEALGWPLEPTFYIPEEVLAHFRQ
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEECHHHHHHHHHH
ALDHGAAAEQAWNELLERYTAAHPEKAADFKQRMSGELPAGWDSTLPVWPADAKGVATRK
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
SSETALNALAEQIPALIGGSADLAESTFTLIEHAQSFQADTPQGRNMHWGIREHAMVAAV
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHEEEEEE
NGMALHGGTIPYGATFLVFSDYCRASIRLAALMGIRTIQVFTHDSIGVGEDGPTHQPIEH
CCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCHHH
IPSLRIIPNLNVMRPGDANETSQAWRVAVSHKGPTLLALTRQNLPTLDRTRYASAEGVAQ
CCCEEEECCCCEECCCCCCCCCHHEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCCC
GGYVLADSAGQPELIIIATGSELQHAVAAYEQLSGEGVKVRVVSMPSTLLFDAQSVEYRE
CCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHH
SVLPKAVTKRIAIEAAHPVTWYKYVGTEGDIIGIDHFGASAPINILMKEFGFTAENLIAR
HHHHHHHHHHHHEECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHH
AKALLAK
HHHHHCC
>Mature Secondary Structure 
TQAHTLDERAINTIRMLSVDGVQAANSGHPGLPMGAAAMAYVLWTRHLKHNPANPDWAD
CCCCCCHHHHHCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
RDRFVLSAGHGSMLLYSLLHLTGYDLSLDDLKNFRQWHSKTAGHPEYGYAAGIETTTGPL
CCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCC
GQGFATGVGMAIAARHLAGTFNQPELEIVKHHIYAIVSDGDLEEGISAEAASLAGHLKLG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEECCCHHHCCCHHHHHHHCCEEEC
ELIYLYDDNEISIEGDTSIAFTEDVPARFRAYGWHVQEIDGLDPEQVDAALHAAKAVTDQ
CEEEEEECCEEEEECCCEEEEECCCCHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHCCC
PSLIVAHTVIGFGSPNRAGTAKAHGSPLGPDEVKLTKEALGWPLEPTFYIPEEVLAHFRQ
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEECHHHHHHHHHH
ALDHGAAAEQAWNELLERYTAAHPEKAADFKQRMSGELPAGWDSTLPVWPADAKGVATRK
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
SSETALNALAEQIPALIGGSADLAESTFTLIEHAQSFQADTPQGRNMHWGIREHAMVAAV
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHEEEEEE
NGMALHGGTIPYGATFLVFSDYCRASIRLAALMGIRTIQVFTHDSIGVGEDGPTHQPIEH
CCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCHHH
IPSLRIIPNLNVMRPGDANETSQAWRVAVSHKGPTLLALTRQNLPTLDRTRYASAEGVAQ
CCCEEEECCCCEECCCCCCCCCHHEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCCC
GGYVLADSAGQPELIIIATGSELQHAVAAYEQLSGEGVKVRVVSMPSTLLFDAQSVEYRE
CCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHH
SVLPKAVTKRIAIEAAHPVTWYKYVGTEGDIIGIDHFGASAPINILMKEFGFTAENLIAR
HHHHHHHHHHHHEECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHH
AKALLAK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]