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The map label for this gene is gph [C]

Identifier: 159896916

GI number: 159896916

Start: 455418

End: 456086

Strand: Direct

Name: gph [C]

Synonym: Haur_0384

Alternate gene names: 159896916

Gene position: 455418-456086 (Clockwise)

Preceding gene: 159896913

Following gene: 159896917

Centisome position: 7.18

GC content: 49.78

Gene sequence:

>669_bases
ATGGTCACAACTACCCAGCGATTTCAATTGTTGGCCTTCGATTTAGATGGAACGTTGGTCGATTCGGCTCAAGGGATTGT
GGATACTGTGAATCAAGTGCTGGCTGAGCATGGTTTTGCAACTGCGGCCTATAGCCAGATGGCTCCATGGATTGGCTTGC
CCTTGCAGGTATTTTGGGAGCGCTTGACTGATTTTCAGCCTGAAAACTATGGAATTTTGACTGAGCGTTATCGCACAATT
TACCGTGAAATTGCGATTCCAAGCAGCCGCTTATTTGCAGGCGTGGCCGAAACGATCGATCAACTTAAATCAGCAGGCTA
TCGTTTGACGATTGCCAGCTCAAAAATTACGCCAGTGAGCAGCGCAGTGCTGCAACAAGTTGGCTTGTTTGGCTATTTTG
ATTTGCTGATGGGCAACGATTCGGTCAGCCAACCCAAGCCCCATGCCGAAATGCTGGCTAAAACCTTGGCCCATTTTGGG
CTGAATGCGACCCAAGCCTTGATGATTGGCGATACCATCCATGACATTACGCTTGGTCACAACGCCCAAGTTGCTAGTTT
GGCAGTTACGACTGGCACCCATGATCTGGCAACATTAACTGCCGCCCAGCCACTGGCCATTTTGAATCAGCTCCATGAAC
TGCCTGCTTGGTTGGCGCAACCAGCCTGA

Upstream 100 bases:

>100_bases
AACCATGGCGATTTTTCGCATGCAAGCATGGGCAATTTGCGAAATTGGCCGAAAGTTGCATAATTATTCTTTGGATTATG
CGCCTAACTAGGAGCGGGTG

Downstream 100 bases:

>100_bases
ATGGTACAATAACAACATCTCAACTTCTGGAGGATTGTATGCCACAATATAAAAATCGTATGTATCGCAAGGAATGGCTC
TCGGAACGCCGTAAATTGGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MVTTTQRFQLLAFDLDGTLVDSAQGIVDTVNQVLAEHGFATAAYSQMAPWIGLPLQVFWERLTDFQPENYGILTERYRTI
YREIAIPSSRLFAGVAETIDQLKSAGYRLTIASSKITPVSSAVLQQVGLFGYFDLLMGNDSVSQPKPHAEMLAKTLAHFG
LNATQALMIGDTIHDITLGHNAQVASLAVTTGTHDLATLTAAQPLAILNQLHELPAWLAQPA

Sequences:

>Translated_222_residues
MVTTTQRFQLLAFDLDGTLVDSAQGIVDTVNQVLAEHGFATAAYSQMAPWIGLPLQVFWERLTDFQPENYGILTERYRTI
YREIAIPSSRLFAGVAETIDQLKSAGYRLTIASSKITPVSSAVLQQVGLFGYFDLLMGNDSVSQPKPHAEMLAKTLAHFG
LNATQALMIGDTIHDITLGHNAQVASLAVTTGTHDLATLTAAQPLAILNQLHELPAWLAQPA
>Mature_222_residues
MVTTTQRFQLLAFDLDGTLVDSAQGIVDTVNQVLAEHGFATAAYSQMAPWIGLPLQVFWERLTDFQPENYGILTERYRTI
YREIAIPSSRLFAGVAETIDQLKSAGYRLTIASSKITPVSSAVLQQVGLFGYFDLLMGNDSVSQPKPHAEMLAKTLAHFG
LNATQALMIGDTIHDITLGHNAQVASLAVTTGTHDLATLTAAQPLAILNQLHELPAWLAQPA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=233, Percent_Identity=29.1845493562232, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24106; Mature: 24106

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTTQRFQLLAFDLDGTLVDSAQGIVDTVNQVLAEHGFATAAYSQMAPWIGLPLQVFWE
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHH
RLTDFQPENYGILTERYRTIYREIAIPSSRLFAGVAETIDQLKSAGYRLTIASSKITPVS
HHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHH
SAVLQQVGLFGYFDLLMGNDSVSQPKPHAEMLAKTLAHFGLNATQALMIGDTIHDITLGH
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHEEECCCHHHEECCC
NAQVASLAVTTGTHDLATLTAAQPLAILNQLHELPAWLAQPA
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVTTTQRFQLLAFDLDGTLVDSAQGIVDTVNQVLAEHGFATAAYSQMAPWIGLPLQVFWE
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHH
RLTDFQPENYGILTERYRTIYREIAIPSSRLFAGVAETIDQLKSAGYRLTIASSKITPVS
HHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHH
SAVLQQVGLFGYFDLLMGNDSVSQPKPHAEMLAKTLAHFGLNATQALMIGDTIHDITLGH
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHEEECCCHHHEECCC
NAQVASLAVTTGTHDLATLTAAQPLAILNQLHELPAWLAQPA
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA