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The map label for this gene is sucD

Identifier: 15926829

GI number: 15926829

Start: 1232447

End: 1233355

Strand: Direct

Name: sucD

Synonym: SA1089

Alternate gene names: 15926829

Gene position: 1232447-1233355 (Clockwise)

Preceding gene: 15926828

Following gene: 15926830

Centisome position: 43.78

GC content: 38.17

Gene sequence:

>909_bases
ATGAGTGTATTTATAGATAAGAATACTAAAGTAATGGTACAAGGTATTACAGGGTCTACTGCCCTTTTCCATACAAAACA
AATGCTTGATTATGGTACGAAAATAGTAGCAGGTGTGACGCCTGGTAAAGGTGGTCAAGTTGTTGAAGGCGTTCCTGTTT
TCAACACTGTTGAAGAAGCTAAAAATGAAACTGGGGCAACGGTTTCAGTCATTTACGTTCCAGCACCATTTGCTGCAGAC
TCAATTTTAGAAGCAGCTGATGCAGACTTAGATATGGTTATTTGTATCACTGAACATATTCCTGTATTAGACATGGTTAA
AGTTAAACGCTACTTACAAGGTAGAAAAACACGTTTAGTTGGTCCGAACTGTCCAGGTGTGATTACAGCAGATGAATGTA
AAATTGGTATTATGCCTGGCTATATTCACAAAAAAGGTCATGTTGGTGTAGTATCACGTTCAGGTACACTAACATATGAA
GCAGTGCACCAATTGACTGAAGAAGGTATTGGTCAAACTACAGCTGTTGGTATTGGTGGAGACCCAGTCAACGGAACAAA
CTTTATTGATGTTTTAAAAGCATTCAATGAAGATGACGAAACGAAAGCAGTTGTTATGATTGGTGAAATCGGTGGTACAG
CTGAAGAAGAAGCAGCTGAATGGATTAAAGCGAATATGACAAAACCAGTTGTAGGCTTTATCGGTGGACAAACAGCACCT
CCTGGAAAACGTATGGGACATGCTGGTGCAATCATTTCAGGTGGTAAAGGTACTGCTGAAGAGAAAATAAAAACATTAAA
TAGTTGTGGTGTGAAAACAGCGGCAACACCTTCAGAAATTGGTTCAACATTAATTGAAGCTGCTAAAGAAGCAGGTATTT
ATGAATCATTATTAACAGTTAATAAATAA

Upstream 100 bases:

>100_bases
CTCAGGATTAGCAATTGAACCAGCAGCAACAATGGCTGAAGGTGCACAAAAAATTGTTAAACTAGTCAAAGAAGCATAAG
GAAAGGATGGGAGCACTAAG

Downstream 100 bases:

>100_bases
AGTTAAAAGATGATATAAATGGCTATAGCCCATTCCATACTTTATAAAAGTATCGGAAATGGGCTATTTGTCGTGCAATG
AATTTTAGTACACTTTTCAT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAAD
SILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYE
AVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAP
PGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYESLLTVNK

Sequences:

>Translated_302_residues
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAAD
SILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYE
AVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAP
PGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYESLLTVNK
>Mature_301_residues
SVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADS
ILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEA
VHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPP
GKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYESLLTVNK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=61.5916955017301, Blast_Score=314, Evalue=5e-86,
Organism=Homo sapiens, GI38569423, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI38569421, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786949, Length=284, Percent_Identity=65.1408450704225, Blast_Score=371, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=61.8055555555556, Blast_Score=339, Evalue=9e-94,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=58.4192439862543, Blast_Score=329, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17557344, Length=264, Percent_Identity=26.1363636363636, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=46.5986394557823, Blast_Score=255, Evalue=5e-69,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=57.1428571428571, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=55.6701030927835, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI281363477, Length=296, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281363475, Length=296, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281363473, Length=296, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SUCD_STAAC (Q5HGI6)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186121.1
- ProteinModelPortal:   Q5HGI6
- SMR:   Q5HGI6
- STRING:   Q5HGI6
- EnsemblBacteria:   EBSTAT00000010022
- GeneID:   3238355
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1263
- TIGR:   SACOL1263
- eggNOG:   COG0074
- GeneTree:   EBGT00050000024511
- HOGENOM:   HBG615372
- OMA:   ADAICEA
- ProtClustDB:   PRK05678
- BioCyc:   SAUR93062:SACOL1263-MONOMER
- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:3.40.50.261
- PIRSF:   PIRSF001553
- PRINTS:   PR01798
- SMART:   SM00881
- TIGRFAMs:   TIGR01019

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 31543; Mature: 31411

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01216 SUCCINYL_COA_LIG_1; PS00399 SUCCINYL_COA_LIG_2

Important sites: ACT_SITE 247-247

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEA
CEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCHHHHHHH
KNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLV
CCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGG
CCCCCCEEEECCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCC
DPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYESLLTV
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHC
NK
CC
>Mature Secondary Structure 
SVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEA
EEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCHHHHHHH
KNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLV
CCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGG
CCCCCCEEEECCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCC
DPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYESLLTV
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHC
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA