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The map label for this gene is sucC

Identifier: 15926828

GI number: 15926828

Start: 1231259

End: 1232425

Strand: Direct

Name: sucC

Synonym: SA1088

Alternate gene names: 15926828

Gene position: 1231259-1232425 (Clockwise)

Preceding gene: 15926827

Following gene: 15926829

Centisome position: 43.74

GC content: 35.39

Gene sequence:

>1167_bases
ATGAATATCCACGAGTATCAAGGTAAAGAAATATTTCGTTCAATGGGCGTTGCAGTTCCAGAAGGACGAGTAGCATTTAC
TGCTGAAGAAGCGGTGGAGAAAGCAAAAGAATTAAATTCTGATGTATATGTTGTAAAAGCACAAATTCATGCTGGAGGTA
GAGGTAAAGCAGGCGGAGTAAAAATTGCTAAATCTTTATCTGAGGTAGAAACATATGCAAAAGAATTATTAGGGAAAACT
TTGGTGACACATCAAACTGGTCCAGAAGGTAAAGAAATTAAACGTTTATATATCGAAGAAGGTTGTGCTATTCAAAAAGA
ATATTACGTTGGATTCGTTATTGATCGTGCGACTGACCAAGTAACATTGATGGCGTCTGAAGAAGGGGGCACTGAGATTG
AAGAAGTTGCTGCGAAGACTCCTGAAAAGATCTTCAAAGAAACTATCGATCCAGTAATCGGACTTTCACCATTCCAAGCA
AGACGAATTGCGTTTAATATTAATATTCCTAAAGAATCTGTTAACAAAGCTGCTAAATTCTTATTAGCACTTTATAATGT
ATTCATTGAAAAAGATTGTTCAATCGTAGAAATCAACCCATTAGTTACAACAGCTGATGGTGATGTATTGGCATTAGATG
CTAAAATTAATTTTGATGATAATGCATTATTCAGACATAAAGATGTTGTAGAATTACGTGATTTAGAAGAAGAAGATCCG
AAAGAGATTGAAGCGTCTAAACATGATTTATCATACATTGCATTAGATGGTGACATCGGATGTATGGTTAATGGTGCAGG
TTTAGCCATGGCAACAATGGATACGATTAATCATTTCGGTGGAAACCCAGCCAATTTCTTAGATGCAGGCGGAAGCGCTA
CTAGAGAAAAAGTAACTGAAGCATTTAAAATCATTTTAGGTGATGAAAATGTTAAAGGTATTTTTGTAAACATTTTCGGT
GGCATTATGAAATGTGATGTTATCGCAGAAGGTATCGTTGAAGCTGTAAAAGAAGTAGATTTAACTTTACCACTAGTTGT
ACGCTTAGAAGGTACAAATGTTGAGTTAGGTAAAAAAATCTTAAAAGACTCAGGATTAGCAATTGAACCAGCAGCAACAA
TGGCTGAAGGTGCACAAAAAATTGTTAAACTAGTCAAAGAAGCATAA

Upstream 100 bases:

>100_bases
ATTCAATTAAATGATAAAAAAGTAGCATTTAAGTTTACAATAGCGCTTACATTTTTTATAATTGTAAGGGAACTTAACCT
AAGTAACAGGAGGATGGAAG

Downstream 100 bases:

>100_bases
GGAAAGGATGGGAGCACTAAGATGAGTGTATTTATAGATAAGAATACTAAAGTAATGGTACAAGGTATTACAGGGTCTAC
TGCCCTTTTCCATACAAAAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKT
LVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDP
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFG
GIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA

Sequences:

>Translated_388_residues
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKT
LVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDP
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFG
GIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>Mature_388_residues
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKT
LVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
RRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDP
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFG
GIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=46.5473145780051, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=47.8835978835979, Blast_Score=337, Evalue=2e-92,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=47.5138121546961, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=50.5181347150259, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=46.0358056265985, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.3846153846154, Blast_Score=327, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.4444444444444, Blast_Score=345, Evalue=5e-96,
Organism=Drosophila melanogaster, GI161078106, Length=400, Percent_Identity=45.25, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24645208, Length=400, Percent_Identity=45.25, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI281361397, Length=401, Percent_Identity=45.3865336658354, Blast_Score=334, Evalue=5e-92,
Organism=Drosophila melanogaster, GI281361395, Length=401, Percent_Identity=45.3865336658354, Blast_Score=334, Evalue=5e-92,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=43.8461538461538, Blast_Score=315, Evalue=4e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_STAA1 (A7X1L8)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441825.1
- ProteinModelPortal:   A7X1L8
- SMR:   A7X1L8
- STRING:   A7X1L8
- EnsemblBacteria:   EBSTAT00000004489
- GeneID:   5561603
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1235
- eggNOG:   COG0045
- GeneTree:   EBGT00050000025407
- HOGENOM:   HBG315432
- OMA:   KKELYVS
- ProtClustDB:   PRK00696
- BioCyc:   SAUR418127:SAHV_1235-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42057; Mature: 42057

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGV
CCCCHHCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCE
VTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKF
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHH
LLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDP
HHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCCCCCC
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTE
HHHHCCCCCEEEEEECCCCEEEEECCCEEHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHH
AFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKI
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LKDSGLAIEPAATMAEGAQKIVKLVKEA
HHCCCCEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGV
CCCCHHCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCE
VTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKF
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHH
LLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDP
HHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEEECCCCCCEECCCCHHHHHCCCCCCC
KEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTE
HHHHCCCCCEEEEEECCCCEEEEECCCEEHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHH
AFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKI
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LKDSGLAIEPAATMAEGAQKIVKLVKEA
HHCCCCEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA