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The map label for this gene is hchA

Identifier: 15926229

GI number: 15926229

Start: 595059

End: 595937

Strand: Direct

Name: hchA

Synonym: SA0509

Alternate gene names: 15926229

Gene position: 595059-595937 (Clockwise)

Preceding gene: 161376699

Following gene: 15926230

Centisome position: 21.14

GC content: 34.36

Gene sequence:

>879_bases
ATGTCACAAGATGTAAATGAATTAAGTAAGCAACCAACGCCAGATAAAGCAGAAGATAACGCATTTTTCCCATCACCATA
TTCCCTTAGTCAATATACAGCACCTAAAACAGATTTTGATGGTGTTGAACACAAAGGTGCCTATAAAGATGGTAAATGGA
AAGTATTGATGATTGCTGCTGAAGAGAGATATGTATTATTGGAAAATGGAAAAATGTTCTCTACGGGTAATCATCCTGTT
GAAATGTTATTACCTTTACATCATTTAATGGAAGCAGGTTTTGACGTTGATGTTGCGACATTATCTGGTTATCCAGTTAA
ATTAGAATTATGGGCTATGCCAACTGAAGACGAGGCAGTTATAAGTACTTATAATAAATTGAAAGAAAAATTAAAACAGC
CAAAAAAATTAGCAGATGTGATTAAAAATGAATTAGGACCTGATTCAGACTATTTATCTGTCTTTATCCCAGGCGGACAT
GCTGCAGTTGTTGGTATTTCTGAAAGTGAGGACGTTCAACAAACATTAGATTGGGCATTAGACAATGACCGCTTTATAGT
TACATTATGTCATGGACCAGCAGCACTACTTTCAGCAGGGCTTAACAGAGAAAAATCTCCATTAGAAGGATACTCTGTTT
GTGTCTTCCCTGACTCATTAGATGAAGGTGCAAATATTGAAATAGGTTATTTACCTGGACGCTTGAAATGGTTAGTTGCT
GATTTATTAACTAAACAAGGATTAAAAGTAGTTAACGACGATATGACAGGAAGAACGTTAAAAGATCGTAAATTATTAAC
AGGTGACAGTCCTTTAGCTTCAAATGAGTTAGGAAAATTAGCAGTTAATGAAATGTTAAATGCAATACAAAATAAATAA

Upstream 100 bases:

>100_bases
ATTATTTTTGATAATGAGTATTTTAATAGTAATACATGTTTATAGTGTGTAGTATATGTCTATACTAGTAGTAACTATAT
AGAGAAAGTAGGAATAAACT

Downstream 100 bases:

>100_bases
TTAAATATTAATTAGAGGAGCCTCATATGTAAATGTATGAGGACTCTTTTTTTTGGCAAAATTTAAGTGATACTTGTAAA
ATAGAACCTATTATGAGTAT

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPV
EMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGH
AAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
DLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK

Sequences:

>Translated_292_residues
MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPV
EMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGH
AAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
DLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
>Mature_291_residues
SQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVE
MLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHA
AVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVAD
LLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily

Homologues:

Organism=Escherichia coli, GI1788278, Length=282, Percent_Identity=56.0283687943262, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HCHA_STAA1 (A7WYY0)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441139.1
- ProteinModelPortal:   A7WYY0
- SMR:   A7WYY0
- STRING:   A7WYY0
- EnsemblBacteria:   EBSTAT00000004300
- GeneID:   5559654
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0549
- eggNOG:   COG0693
- GeneTree:   EBGT00050000025075
- HOGENOM:   HBG289938
- OMA:   LPMYHLD
- ProtClustDB:   PRK04155
- BioCyc:   SAUR418127:SAHV_0549-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01046
- InterPro:   IPR017283
- InterPro:   IPR002818
- PIRSF:   PIRSF037798

Pfam domain/function: PF01965 DJ-1_PfpI

EC number: NA

Molecular weight: Translated: 32177; Mature: 32046

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: ACT_SITE 190-190 ACT_SITE 191-191 ACT_SITE 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAA
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
EERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAV
CCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCHHH
ISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWAL
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHC
DNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
CCCCEEEEEECCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHH
DLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
HHHHHCCCEEECCCCCCCEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAA
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
EERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAV
CCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCHHH
ISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWAL
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHC
DNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVA
CCCCEEEEEECCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHH
DLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK
HHHHHCCCEEECCCCCCCEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA