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The map label for this gene is purR

Identifier: 15926173

GI number: 15926173

Start: 525107

End: 525931

Strand: Direct

Name: purR

Synonym: SA0454

Alternate gene names: 15926173

Gene position: 525107-525931 (Clockwise)

Preceding gene: 15926172

Following gene: 15926174

Centisome position: 18.66

GC content: 32.24

Gene sequence:

>825_bases
ATGAGATATAAACGAAGCGAGAGAATTGTTTTTATGACGCAATATTTGATGAACCATCCGAATAAATTGATTCCATTAAC
TTTTTTTGTGAAAAAATTTAAACAGGCGAAATCTTCAATAAGTGAAGATGTCCAAATTATAAAAAATACATTCCAAAAAG
AAAAGTTAGGTACAGTAATTACTACTGCTGGCGCAAGTGGTGGTGTTACGTATAAACCAATGATGAGTAAAGAAGAGGCG
ACTGAAGTTGTTAATGAGGTCATTACTCTATTAGAAGAGAAAGAACGTTTGTTACCTGGCGGGTATTTATTTTTATCAGA
TTTGGTAGGTAATCCATCGCTACTAAACAAAGTTGGTAAGTTAATTGCCAGTATTTACATGGAAGAAAAATTAGATGCTG
TTGTTACCATTGCGACAAAAGGTATTTCATTGGCAAATGCGGTTGCTAATATTTTAAATTTACCAGTAGTAGTGATTAGA
AAAGACAACAAGGTGACTGAAGGTTCTACAGTTTCAATTAATTACGTTTCAGGATCTTCAAGAAAAATAGAGACAATGGT
ACTTTCGAAGAGAACTTTAGCAGAAAATTCAAATGTTTTAGTTGTCGATGATTTTATGAGGGCTGGTGGCTCTATTAATG
GTGTTATGAATTTAATGAATGAGTTTAAAGCCCATGTAAAAGGGGTATCAGTACTTGTAGAATCAAAAGAAGTTAAACAA
AGATTGATTGAAGATTATACTTCCTTAGTGAAATTATCTGATGTAGATGAATATAATCAAGAGTTTAACGTAGAACCTGG
CAACAGTTTATCTAAGTTTTCATAA

Upstream 100 bases:

>100_bases
GCACGAAAAGAAAGCCAAGCAAAAAATATTTATAATGCAGTTAACGGTTGTTGTAATGAAGTGTACTTAGTTAGACTATT
AGGATAGAAGGGTTGAAAAG

Downstream 100 bases:

>100_bases
AAGGAGTTTTAGTATTATGAAAATCATTAACACAACAAGATTACCGGAAGCACTTGGACCATATTCGCATGCAACAGTTG
TGAATGGTATGGTTTATACT

Product: pur operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDVQIIKNTFQKEKLGTVITTAGASGGVTYKPMMSKEEA
TEVVNEVITLLEEKERLLPGGYLFLSDLVGNPSLLNKVGKLIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIR
KDNKVTEGSTVSINYVSGSSRKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNLMNEFKAHVKGVSVLVESKEVKQ
RLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS

Sequences:

>Translated_274_residues
MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDVQIIKNTFQKEKLGTVITTAGASGGVTYKPMMSKEEA
TEVVNEVITLLEEKERLLPGGYLFLSDLVGNPSLLNKVGKLIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIR
KDNKVTEGSTVSINYVSGSSRKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNLMNEFKAHVKGVSVLVESKEVKQ
RLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS
>Mature_274_residues
MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDVQIIKNTFQKEKLGTVITTAGASGGVTYKPMMSKEEA
TEVVNEVITLLEEKERLLPGGYLFLSDLVGNPSLLNKVGKLIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIR
KDNKVTEGSTVSINYVSGSSRKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNLMNEFKAHVKGVSVLVESKEVKQ
RLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS

Specific function: Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR015265
- InterPro:   IPR010078
- InterPro:   IPR011991
- ProDom:   PD029816 [H]

Pfam domain/function: PF00156 Pribosyltran; PF09182 PuR_N [H]

EC number: NA

Molecular weight: Translated: 30396; Mature: 30396

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDVQIIKNTFQKEKLGTVI
CCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
TTAGASGGVTYKPMMSKEEATEVVNEVITLLEEKERLLPGGYLFLSDLVGNPSLLNKVGK
EECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
LIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIRKDNKVTEGSTVSINYVSGSS
HHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCC
RKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNLMNEFKAHVKGVSVLVESKEVKQ
CCHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHH
RLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS
HHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDVQIIKNTFQKEKLGTVI
CCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
TTAGASGGVTYKPMMSKEEATEVVNEVITLLEEKERLLPGGYLFLSDLVGNPSLLNKVGK
EECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
LIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIRKDNKVTEGSTVSINYVSGSS
HHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCC
RKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNLMNEFKAHVKGVSVLVESKEVKQ
CCHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHH
RLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS
HHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7638212 [H]