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The map label for this gene is 15921635

Identifier: 15921635

GI number: 15921635

Start: 1358368

End: 1359459

Strand: Direct

Name: 15921635

Synonym: ST1350

Alternate gene names: NA

Gene position: 1358368-1359459 (Clockwise)

Preceding gene: 15921634

Following gene: 15921636

Centisome position: 50.41

GC content: 32.51

Gene sequence:

>1092_bases
ATGGTTTCAATAGCTGAAGTTTCTTTCATAAAGATTGATCGCTATTATGAGTATTCTGAAAAAGATTTAGTTATAGAGGC
TTATAAGCAAATAGAAACTAAGGTAAAAGATTACATAAAACCAGATGTAGTTATAGTCTCAAGTGGTTATGCTGAGAGTA
TTGGAAAATCTTCTTTATCAGCTGTAAAACTCTCATCTTCTCTTGGATTTAAAGGGGTAAGAACATTTAGAATAGAAAAT
GGAGATAATGGAGGACCTTCTATTTATACTGCTTATTCTCTTATAAAATCTGGATTAGCAAAATCAGTACTTCTAATTGG
AGTTGATAAATTTTCAGATCTAGCTTCAAAACAGCTTAATGATGTTTTAGCTATGAATTTACTTCACGATCATGAATATC
ATTTAGGATTAACTCCCCACTCATATGCAGCTATTTTAGCTAAACTTTATATGAAAAAATATAATGTTCCATATGAATAT
TTTGCAAACTGGCCATTAAAGATGCATGATAATGCAGTAGAAAATCCGTTCGCATATTTGAGGTTCAAGACAGATCTTAA
AACTATTACTTCATCTCAATTAGTCTCTGAACCTTTAAGAATATTTGATACTGCTGCAAGAGCTGATGGAGCTGGTATTA
TATTATTAACTGATGATGAAGTAGCAAAGAAGTACACAGATACTCCAGTATATTTAGCAAATGTTCATGGAGCAATATAC
GAGTATATATATGATTTAAGTTTACCTTCTATAAGATTAGCTCTAAACGAACTTAAATATACTCCTAATAAGAATGATAT
CATAGAAATTCACGATTCTTATAGCATATTGGCTGCTTTAGAGTTAGAAGAATTAGGTCTGGGAGAAAAGGGTAAATCAT
TACTAGAACTGGATTCTTATCAGATAAACTATAGTGGTGGTCTAAAAGCTAGGGGTTATCCTGGAGGAGCTACAGCTATT
TATCAGCTAGCTGAGGTTGTTATGCAGCTTAGAGGCGAATTTCCGGGAAAGAAAGCTATAGGTGAAAGTGGGGTAGTTAT
TTCGGCAGACGATTTAGTCACATCTTCTTATATTTCAATTTTAAAGAGGTGA

Upstream 100 bases:

>100_bases
AAAAACTTGCGCCAAGAGTTGAAGATTATATTAATAATAAGAAAGTAATTTCATACTCTGTTTATGCAAAGACAACAAAC
AAATACAAGGTGTATGAGTA

Downstream 100 bases:

>100_bases
AGTTAAAAGTGAAAATTAGTCCTCCAAGAAATTGGAGGTTAAAAGAAACTTTATATTCAATTGTTTTAGGCAAGTGTGAA
AAATGCGGAAATATAATGTA

Product: acetyl-CoA synthase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MVSIAEVSFIKIDRYYEYSEKDLVIEAYKQIETKVKDYIKPDVVIVSSGYAESIGKSSLSAVKLSSSLGFKGVRTFRIEN
GDNGGPSIYTAYSLIKSGLAKSVLLIGVDKFSDLASKQLNDVLAMNLLHDHEYHLGLTPHSYAAILAKLYMKKYNVPYEY
FANWPLKMHDNAVENPFAYLRFKTDLKTITSSQLVSEPLRIFDTAARADGAGIILLTDDEVAKKYTDTPVYLANVHGAIY
EYIYDLSLPSIRLALNELKYTPNKNDIIEIHDSYSILAALELEELGLGEKGKSLLELDSYQINYSGGLKARGYPGGATAI
YQLAEVVMQLRGEFPGKKAIGESGVVISADDLVTSSYISILKR

Sequences:

>Translated_363_residues
MVSIAEVSFIKIDRYYEYSEKDLVIEAYKQIETKVKDYIKPDVVIVSSGYAESIGKSSLSAVKLSSSLGFKGVRTFRIEN
GDNGGPSIYTAYSLIKSGLAKSVLLIGVDKFSDLASKQLNDVLAMNLLHDHEYHLGLTPHSYAAILAKLYMKKYNVPYEY
FANWPLKMHDNAVENPFAYLRFKTDLKTITSSQLVSEPLRIFDTAARADGAGIILLTDDEVAKKYTDTPVYLANVHGAIY
EYIYDLSLPSIRLALNELKYTPNKNDIIEIHDSYSILAALELEELGLGEKGKSLLELDSYQINYSGGLKARGYPGGATAI
YQLAEVVMQLRGEFPGKKAIGESGVVISADDLVTSSYISILKR
>Mature_363_residues
MVSIAEVSFIKIDRYYEYSEKDLVIEAYKQIETKVKDYIKPDVVIVSSGYAESIGKSSLSAVKLSSSLGFKGVRTFRIEN
GDNGGPSIYTAYSLIKSGLAKSVLLIGVDKFSDLASKQLNDVLAMNLLHDHEYHLGLTPHSYAAILAKLYMKKYNVPYEY
FANWPLKMHDNAVENPFAYLRFKTDLKTITSSQLVSEPLRIFDTAARADGAGIILLTDDEVAKKYTDTPVYLANVHGAIY
EYIYDLSLPSIRLALNELKYTPNKNDIIEIHDSYSILAALELEELGLGEKGKSLLELDSYQINYSGGLKARGYPGGATAI
YQLAEVVMQLRGEFPGKKAIGESGVVISADDLVTSSYISILKR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344760, Length=323, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI19923233, Length=374, Percent_Identity=27.0053475935829, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI302344767, Length=293, Percent_Identity=29.6928327645051, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI302344762, Length=276, Percent_Identity=28.9855072463768, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI55956775, Length=260, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=393, Percent_Identity=23.9185750636132, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24585051, Length=377, Percent_Identity=25.7294429708223, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921506, Length=301, Percent_Identity=27.906976744186, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40224; Mature: 40224

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIAEVSFIKIDRYYEYSEKDLVIEAYKQIETKVKDYIKPDVVIVSSGYAESIGKSSLS
CCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCHHHHH
AVKLSSSLGFKGVRTFRIENGDNGGPSIYTAYSLIKSGLAKSVLLIGVDKFSDLASKQLN
HEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHH
DVLAMNLLHDHEYHLGLTPHSYAAILAKLYMKKYNVPYEYFANWPLKMHDNAVENPFAYL
HHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHCCCCEEECCCCCCCCEEEE
RFKTDLKTITSSQLVSEPLRIFDTAARADGAGIILLTDDEVAKKYTDTPVYLANVHGAIY
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCEEEEHHHHHHH
EYIYDLSLPSIRLALNELKYTPNKNDIIEIHDSYSILAALELEELGLGEKGKSLLELDSY
HHHHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEHHHCCCCCCCCHHEEECCE
QINYSGGLKARGYPGGATAIYQLAEVVMQLRGEFPGKKAIGESGVVISADDLVTSSYISI
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECHHHHHHHHHHH
LKR
HCC
>Mature Secondary Structure
MVSIAEVSFIKIDRYYEYSEKDLVIEAYKQIETKVKDYIKPDVVIVSSGYAESIGKSSLS
CCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCHHHHH
AVKLSSSLGFKGVRTFRIENGDNGGPSIYTAYSLIKSGLAKSVLLIGVDKFSDLASKQLN
HEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHH
DVLAMNLLHDHEYHLGLTPHSYAAILAKLYMKKYNVPYEYFANWPLKMHDNAVENPFAYL
HHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHCCCCEEECCCCCCCCEEEE
RFKTDLKTITSSQLVSEPLRIFDTAARADGAGIILLTDDEVAKKYTDTPVYLANVHGAIY
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCEEEEHHHHHHH
EYIYDLSLPSIRLALNELKYTPNKNDIIEIHDSYSILAALELEELGLGEKGKSLLELDSY
HHHHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEHHHCCCCCCCCHHEEECCE
QINYSGGLKARGYPGGATAIYQLAEVVMQLRGEFPGKKAIGESGVVISADDLVTSSYISI
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECHHHHHHHHHHH
LKR
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]