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The map label for this gene is lrp [C]

Identifier: 15921370

GI number: 15921370

Start: 1104652

End: 1105107

Strand: Direct

Name: lrp [C]

Synonym: ST1115

Alternate gene names: 15921370

Gene position: 1104652-1105107 (Clockwise)

Preceding gene: 15921367

Following gene: 15921375

Centisome position: 40.99

GC content: 30.48

Gene sequence:

>456_bases
ATGGATGAAATAGATTTAAAGATTCTAAAAATACTTCAGAAAGATGCAAAATACTCATTAGAAGATTTAAGTACTGAATT
GAAAATGCCTAAGTCAACAGTAGCATATAGGATTAAGAGATTGGAATCTTTAAATATTATAAAAGGGTATTATGCTCAAA
TAGATCCTACCGCATTAAATCTAGATTATATCGTAATCAGCTTAATAAGAGGCAAATACAGTAAAGACTATCATATAGAA
TTGGGCTCTAAGCTAGCTAATATTCCTGGCGTATGGGGTGTGTATTTTGTATTGGGTGATACAGATTTCATAGTAATCGC
TAGATATAGAAATAGGGAAGATTTTATGAAAAACTATTTAGAGAGAATAACAAGTATGCCAGAAGTCGAAAGATCTAGTA
CACATGTTGTAGTTAAAATAATTAAGGAGTCTCCTAATATGGTTATTTGGTGGTAA

Upstream 100 bases:

>100_bases
AATAGCGGTACTATCTTAAAATATTAGTATAAGTATATAGTTGTGTAATTTACTAAAGATATCTTTATATTCTTGTATAT
TATTCAATATTTGATGAAGA

Downstream 100 bases:

>100_bases
GTCTATGTAGCAGAAATTATGTTATATTTGCATGATTCTTAAATTATTAAATAAATAGGATTAAAATACATAATAACTAA
GAAAGAGAGCAAAAATTAAG

Product: leucine-responsive regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MDEIDLKILKILQKDAKYSLEDLSTELKMPKSTVAYRIKRLESLNIIKGYYAQIDPTALNLDYIVISLIRGKYSKDYHIE
LGSKLANIPGVWGVYFVLGDTDFIVIARYRNREDFMKNYLERITSMPEVERSSTHVVVKIIKESPNMVIWW

Sequences:

>Translated_151_residues
MDEIDLKILKILQKDAKYSLEDLSTELKMPKSTVAYRIKRLESLNIIKGYYAQIDPTALNLDYIVISLIRGKYSKDYHIE
LGSKLANIPGVWGVYFVLGDTDFIVIARYRNREDFMKNYLERITSMPEVERSSTHVVVKIIKESPNMVIWW
>Mature_151_residues
MDEIDLKILKILQKDAKYSLEDLSTELKMPKSTVAYRIKRLESLNIIKGYYAQIDPTALNLDYIVISLIRGKYSKDYHIE
LGSKLANIPGVWGVYFVLGDTDFIVIARYRNREDFMKNYLERITSMPEVERSSTHVVVKIIKESPNMVIWW

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=152, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=9e-13,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=24, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17651; Mature: 17651

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIDLKILKILQKDAKYSLEDLSTELKMPKSTVAYRIKRLESLNIIKGYYAQIDPTALN
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEEECCCEEC
LDYIVISLIRGKYSKDYHIELGSKLANIPGVWGVYFVLGDTDFIVIARYRNREDFMKNYL
HHHHHHHHHHCCCCCCEEEEECCHHCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHH
ERITSMPEVERSSTHVVVKIIKESPNMVIWW
HHHHCCCCCCCCCCEEEEEEEECCCCEEEEC
>Mature Secondary Structure
MDEIDLKILKILQKDAKYSLEDLSTELKMPKSTVAYRIKRLESLNIIKGYYAQIDPTALN
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEEECCCEEC
LDYIVISLIRGKYSKDYHIELGSKLANIPGVWGVYFVLGDTDFIVIARYRNREDFMKNYL
HHHHHHHHHHCCCCCCEEEEECCHHCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHH
ERITSMPEVERSSTHVVVKIIKESPNMVIWW
HHHHCCCCCCCCCCEEEEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA