| Definition | Sulfolobus tokodaii str. 7 chromosome, complete genome. |
|---|---|
| Accession | NC_003106 |
| Length | 2,694,756 |
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The map label for this gene is lcfB [H]
Identifier: 15921367
GI number: 15921367
Start: 1099221
End: 1100735
Strand: Direct
Name: lcfB [H]
Synonym: ST1112
Alternate gene names: 15921367
Gene position: 1099221-1100735 (Clockwise)
Preceding gene: 15921366
Following gene: 15921370
Centisome position: 40.79
GC content: 36.7
Gene sequence:
>1515_bases ATGAAATATGCAAAGGGTGAAGAGCTAGAAGAATTGAAATATCCCAAGCCAGTTACAGAAATGATTCCTTCATATGACTC TATAGCTATAGATTATTTCGGTACAAAGATAACGTATAGGGAATTAAACCTAATGATAGATTCTGTAGCCTCACAACTTG ACATAAATAAAGGAGATGTTGTGATTGTTACAATGCAAAACATTCCGCAGTTCATTATCACCGAATTTGCAGTATGGAAA AAAGGAGGAATAGTACTGCCGGTAAATCCCTCTTATACAGAGAAGGAATTAGACTATATAATAGAAAACTCTGAAGCTAA GTTAATGATAAGGTCTTGCGAGGCTATTAACACAAAAAAGATAAGGACTATAACTACTAATCCAGAAACGTTCCATGAAA TTCCTAGTGAATTGAAAGCCAAATGGAAAATAATTGATTGTGAAGAAGAATTAGACTTCAAATCGTTACATCGTGAGAAA GTTGATGTCTCTCCTAATGATCTAGCCTTATTAGTATATACCTCTGGGACCACTGGGAGACCTAAGGGAGTACCTATAAC ACATAAAAATATTTATGCTTCATCCATAATATACAAACACTGGTTTAAGTTTACTGAAAAGGATAAAGTACTGGGAATAG CGCCTTTCTTTCATATTACCGGTCAGATCTTTCACATCACAACACCATTAATTTCGGGAAGTGAGATAGTGATTTCATAC AGGTTTGATCCAACTTTAGCTTTAAGACATGTCGAGGAAAAGAAGACTACAGTAACAATGGCAGTAGCAACTGCATATCG AGCTATTCTCAATGAGTATAAGGGAGAAGATCTCTCAAGTATGAGGCTTTGGTCTTCTGGAGGGATGCCTATGCCCAGAA CGCTTGAAATTGAGTGGAGGGAAAAAATAGGACAATGGATTTACATGGCTTGGGGTCTTACGGAGACTACTTCTCCCGCA ACTCTATGGCCTTACCCTTATAATGGTGAGCTACCAGTAGATCCAGAGACTGGAGTAGTGAGTTCCGGTATACCGGTTTA TAATACTGAGATAAGTATAGCTGAAGATGGTGAAGTTTTAGTTAGAGGACCTCAAGTAGTTTCAGGTTATTGGAAGATGG AGAAATTTAGAGATGGTTGGCTCCCCACGGGAGATATAGGCAAAATAATTGATGGTTGGGTTTACATAATAGATAGAAAG AAGGATATAATTAACGCTTCTGGATTTAAGATTATGCCTAGAGAAGTGGAAGAAGTAATCTACATGCACCCAGCTGTAAG TGAAGTAGCAGTAGTAGGTTTACCAGATCAATATAGAGGTGAAACAGTTGCAGCATTTATAAAGCTAAAGGATGGTTATA CACCAAACGAAAAAGTTGAGGAGGAGATTATATCTTTATGTAGAAAAAATCTAGCGCCATATAAAGTGCCAAAAATTATT AGATTTGTTAATGAGATTCCAAAGACACCATCTGGAAAGATTATGAGAAGAGTTTTCAGAAATGAAAGAATATAA
Upstream 100 bases:
>100_bases AATGGAGATTATACATCTCCAGTTTAATACCAGAATCAAGTAAAAATATTCTGGGAATAAAATAGAAACTCCAAAATTAA GAGAACAAGAGGTATAAACG
Downstream 100 bases:
>100_bases CATCACAGTATTAGTAAACTATCTTTTGAGTGCTTCGTAACGAGATATAACAATATAGCTGTAAAAAATATGTTAAACTA CTTTGTATTTATGACATATT
Product: long-chain-fatty acid--CoA ligase
Products: NA
Alternate protein names: Long-chain acyl-CoA synthetase [H]
Number of amino acids: Translated: 504; Mature: 504
Protein sequence:
>504_residues MKYAKGEELEELKYPKPVTEMIPSYDSIAIDYFGTKITYRELNLMIDSVASQLDINKGDVVIVTMQNIPQFIITEFAVWK KGGIVLPVNPSYTEKELDYIIENSEAKLMIRSCEAINTKKIRTITTNPETFHEIPSELKAKWKIIDCEEELDFKSLHREK VDVSPNDLALLVYTSGTTGRPKGVPITHKNIYASSIIYKHWFKFTEKDKVLGIAPFFHITGQIFHITTPLISGSEIVISY RFDPTLALRHVEEKKTTVTMAVATAYRAILNEYKGEDLSSMRLWSSGGMPMPRTLEIEWREKIGQWIYMAWGLTETTSPA TLWPYPYNGELPVDPETGVVSSGIPVYNTEISIAEDGEVLVRGPQVVSGYWKMEKFRDGWLPTGDIGKIIDGWVYIIDRK KDIINASGFKIMPREVEEVIYMHPAVSEVAVVGLPDQYRGETVAAFIKLKDGYTPNEKVEEEIISLCRKNLAPYKVPKII RFVNEIPKTPSGKIMRRVFRNERI
Sequences:
>Translated_504_residues MKYAKGEELEELKYPKPVTEMIPSYDSIAIDYFGTKITYRELNLMIDSVASQLDINKGDVVIVTMQNIPQFIITEFAVWK KGGIVLPVNPSYTEKELDYIIENSEAKLMIRSCEAINTKKIRTITTNPETFHEIPSELKAKWKIIDCEEELDFKSLHREK VDVSPNDLALLVYTSGTTGRPKGVPITHKNIYASSIIYKHWFKFTEKDKVLGIAPFFHITGQIFHITTPLISGSEIVISY RFDPTLALRHVEEKKTTVTMAVATAYRAILNEYKGEDLSSMRLWSSGGMPMPRTLEIEWREKIGQWIYMAWGLTETTSPA TLWPYPYNGELPVDPETGVVSSGIPVYNTEISIAEDGEVLVRGPQVVSGYWKMEKFRDGWLPTGDIGKIIDGWVYIIDRK KDIINASGFKIMPREVEEVIYMHPAVSEVAVVGLPDQYRGETVAAFIKLKDGYTPNEKVEEEIISLCRKNLAPYKVPKII RFVNEIPKTPSGKIMRRVFRNERI >Mature_504_residues MKYAKGEELEELKYPKPVTEMIPSYDSIAIDYFGTKITYRELNLMIDSVASQLDINKGDVVIVTMQNIPQFIITEFAVWK KGGIVLPVNPSYTEKELDYIIENSEAKLMIRSCEAINTKKIRTITTNPETFHEIPSELKAKWKIIDCEEELDFKSLHREK VDVSPNDLALLVYTSGTTGRPKGVPITHKNIYASSIIYKHWFKFTEKDKVLGIAPFFHITGQIFHITTPLISGSEIVISY RFDPTLALRHVEEKKTTVTMAVATAYRAILNEYKGEDLSSMRLWSSGGMPMPRTLEIEWREKIGQWIYMAWGLTETTSPA TLWPYPYNGELPVDPETGVVSSGIPVYNTEISIAEDGEVLVRGPQVVSGYWKMEKFRDGWLPTGDIGKIIDGWVYIIDRK KDIINASGFKIMPREVEEVIYMHPAVSEVAVVGLPDQYRGETVAAFIKLKDGYTPNEKVEEEIISLCRKNLAPYKVPKII RFVNEIPKTPSGKIMRRVFRNERI
Specific function: Involved in the degradation of long-chain fatty acids [H]
COG id: COG0318
COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
Gene ontology:
Cell location: Partially Membrane-Associated [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]
Homologues:
Organism=Homo sapiens, GI156151445, Length=534, Percent_Identity=27.3408239700375, Blast_Score=171, Evalue=2e-42, Organism=Homo sapiens, GI187761345, Length=540, Percent_Identity=27.2222222222222, Blast_Score=166, Evalue=5e-41, Organism=Homo sapiens, GI187761343, Length=540, Percent_Identity=27.2222222222222, Blast_Score=166, Evalue=5e-41, Organism=Homo sapiens, GI42544132, Length=483, Percent_Identity=26.0869565217391, Blast_Score=156, Evalue=5e-38, Organism=Homo sapiens, GI122937307, Length=505, Percent_Identity=26.3366336633663, Blast_Score=143, Evalue=4e-34, Organism=Homo sapiens, GI115511026, Length=511, Percent_Identity=26.8101761252446, Blast_Score=142, Evalue=7e-34, Organism=Homo sapiens, GI58082049, Length=508, Percent_Identity=27.1653543307087, Blast_Score=141, Evalue=2e-33, Organism=Homo sapiens, GI157311624, Length=512, Percent_Identity=27.1484375, Blast_Score=139, Evalue=5e-33, Organism=Homo sapiens, GI157311622, Length=512, Percent_Identity=27.1484375, Blast_Score=139, Evalue=5e-33, Organism=Homo sapiens, GI38505220, Length=515, Percent_Identity=26.2135922330097, Blast_Score=134, Evalue=2e-31, Organism=Homo sapiens, GI28416953, Length=521, Percent_Identity=27.6391554702495, Blast_Score=126, Evalue=5e-29, Organism=Homo sapiens, GI13375727, Length=543, Percent_Identity=26.8876611418048, Blast_Score=117, Evalue=3e-26, Organism=Homo sapiens, GI8923896, Length=541, Percent_Identity=25.5083179297597, Blast_Score=108, Evalue=1e-23, Organism=Homo sapiens, GI253970489, Length=554, Percent_Identity=25.6317689530686, Blast_Score=107, Evalue=3e-23, Organism=Homo sapiens, GI40807491, Length=496, Percent_Identity=23.3870967741935, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI42544134, Length=275, Percent_Identity=22.5454545454545, Blast_Score=83, Evalue=7e-16, Organism=Escherichia coli, GI1788107, Length=531, Percent_Identity=31.4500941619586, Blast_Score=238, Evalue=9e-64, Organism=Escherichia coli, GI145693145, Length=506, Percent_Identity=26.8774703557312, Blast_Score=179, Evalue=3e-46, Organism=Escherichia coli, GI221142682, Length=504, Percent_Identity=25.9920634920635, Blast_Score=162, Evalue=7e-41, Organism=Escherichia coli, GI1790505, Length=512, Percent_Identity=26.5625, Blast_Score=150, Evalue=1e-37, Organism=Escherichia coli, GI1786810, Length=522, Percent_Identity=25.6704980842912, Blast_Score=133, Evalue=3e-32, Organism=Escherichia coli, GI1789201, Length=364, Percent_Identity=26.0989010989011, Blast_Score=111, Evalue=1e-25, Organism=Escherichia coli, GI1786529, Length=537, Percent_Identity=24.3947858472998, Blast_Score=105, Evalue=1e-23, Organism=Escherichia coli, GI1788595, Length=485, Percent_Identity=23.0927835051546, Blast_Score=96, Evalue=5e-21, Organism=Escherichia coli, GI1786801, Length=431, Percent_Identity=21.3457076566125, Blast_Score=77, Evalue=2e-15, Organism=Caenorhabditis elegans, GI32563687, Length=483, Percent_Identity=29.6066252587992, Blast_Score=185, Evalue=4e-47, Organism=Caenorhabditis elegans, GI17558820, Length=490, Percent_Identity=30.2040816326531, Blast_Score=181, Evalue=7e-46, Organism=Caenorhabditis elegans, GI17557194, Length=520, Percent_Identity=28.6538461538462, Blast_Score=169, Evalue=3e-42, Organism=Caenorhabditis elegans, GI71994690, Length=543, Percent_Identity=27.0718232044199, Blast_Score=168, Evalue=7e-42, Organism=Caenorhabditis elegans, GI71994694, Length=543, Percent_Identity=27.4401473296501, Blast_Score=168, Evalue=7e-42, Organism=Caenorhabditis elegans, GI71994703, Length=543, Percent_Identity=27.0718232044199, Blast_Score=167, Evalue=8e-42, Organism=Caenorhabditis elegans, GI17538037, Length=501, Percent_Identity=26.9461077844311, Blast_Score=162, Evalue=4e-40, Organism=Caenorhabditis elegans, GI17559526, Length=485, Percent_Identity=28.0412371134021, Blast_Score=161, Evalue=1e-39, Organism=Caenorhabditis elegans, GI17531443, Length=524, Percent_Identity=26.5267175572519, Blast_Score=147, Evalue=1e-35, Organism=Caenorhabditis elegans, GI17560308, Length=535, Percent_Identity=24.8598130841122, Blast_Score=136, Evalue=2e-32, Organism=Caenorhabditis elegans, GI71996755, Length=485, Percent_Identity=24.7422680412371, Blast_Score=117, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17560140, Length=508, Percent_Identity=23.8188976377953, Blast_Score=115, Evalue=7e-26, Organism=Caenorhabditis elegans, GI71985884, Length=357, Percent_Identity=27.7310924369748, Blast_Score=104, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17541856, Length=445, Percent_Identity=24.9438202247191, Blast_Score=96, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17556552, Length=450, Percent_Identity=25.7777777777778, Blast_Score=93, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17510401, Length=448, Percent_Identity=23.8839285714286, Blast_Score=92, Evalue=5e-19, Organism=Caenorhabditis elegans, GI25141359, Length=498, Percent_Identity=22.6907630522088, Blast_Score=92, Evalue=7e-19, Organism=Caenorhabditis elegans, GI71982997, Length=536, Percent_Identity=22.7611940298507, Blast_Score=88, Evalue=9e-18, Organism=Caenorhabditis elegans, GI71983001, Length=536, Percent_Identity=22.7611940298507, Blast_Score=88, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17551278, Length=515, Percent_Identity=24.8543689320388, Blast_Score=87, Evalue=2e-17, Organism=Caenorhabditis elegans, GI115534440, Length=515, Percent_Identity=21.3592233009709, Blast_Score=76, Evalue=4e-14, Organism=Caenorhabditis elegans, GI133901848, Length=201, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6319699, Length=506, Percent_Identity=27.2727272727273, Blast_Score=167, Evalue=2e-42, Organism=Saccharomyces cerevisiae, GI6323182, Length=529, Percent_Identity=28.5444234404537, Blast_Score=155, Evalue=2e-38, Organism=Saccharomyces cerevisiae, GI6319264, Length=542, Percent_Identity=27.3062730627306, Blast_Score=145, Evalue=1e-35, Organism=Drosophila melanogaster, GI21355181, Length=481, Percent_Identity=29.9376299376299, Blast_Score=179, Evalue=4e-45, Organism=Drosophila melanogaster, GI18859661, Length=482, Percent_Identity=26.7634854771784, Blast_Score=167, Evalue=2e-41, Organism=Drosophila melanogaster, GI24581924, Length=514, Percent_Identity=25.875486381323, Blast_Score=143, Evalue=3e-34, Organism=Drosophila melanogaster, GI19922652, Length=498, Percent_Identity=25.3012048192771, Blast_Score=122, Evalue=5e-28, Organism=Drosophila melanogaster, GI62472339, Length=545, Percent_Identity=25.5045871559633, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI24667955, Length=542, Percent_Identity=25.4612546125461, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI24648255, Length=494, Percent_Identity=26.3157894736842, Blast_Score=119, Evalue=7e-27, Organism=Drosophila melanogaster, GI24648253, Length=494, Percent_Identity=26.1133603238866, Blast_Score=118, Evalue=8e-27, Organism=Drosophila melanogaster, GI21356441, Length=510, Percent_Identity=23.921568627451, Blast_Score=111, Evalue=1e-24, Organism=Drosophila melanogaster, GI24667959, Length=374, Percent_Identity=27.0053475935829, Blast_Score=111, Evalue=1e-24, Organism=Drosophila melanogaster, GI21355225, Length=545, Percent_Identity=25.1376146788991, Blast_Score=110, Evalue=3e-24, Organism=Drosophila melanogaster, GI24656500, Length=470, Percent_Identity=23.4042553191489, Blast_Score=107, Evalue=2e-23, Organism=Drosophila melanogaster, GI24648676, Length=484, Percent_Identity=24.1735537190083, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI24648260, Length=356, Percent_Identity=26.9662921348315, Blast_Score=95, Evalue=1e-19, Organism=Drosophila melanogaster, GI21358303, Length=445, Percent_Identity=22.9213483146067, Blast_Score=93, Evalue=5e-19, Organism=Drosophila melanogaster, GI24648257, Length=354, Percent_Identity=27.4011299435028, Blast_Score=93, Evalue=5e-19, Organism=Drosophila melanogaster, GI281365686, Length=502, Percent_Identity=21.9123505976096, Blast_Score=88, Evalue=1e-17, Organism=Drosophila melanogaster, GI20130357, Length=353, Percent_Identity=26.3456090651558, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI21356947, Length=497, Percent_Identity=21.7303822937626, Blast_Score=85, Evalue=1e-16, Organism=Drosophila melanogaster, GI24653035, Length=517, Percent_Identity=21.2765957446809, Blast_Score=82, Evalue=1e-15, Organism=Drosophila melanogaster, GI161076582, Length=527, Percent_Identity=20.8728652751423, Blast_Score=76, Evalue=6e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020459 - InterPro: IPR020845 - InterPro: IPR000873 [H]
Pfam domain/function: PF00501 AMP-binding [H]
EC number: =6.2.1.3 [H]
Molecular weight: Translated: 57463; Mature: 57463
Theoretical pI: Translated: 6.35; Mature: 6.35
Prosite motif: PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKYAKGEELEELKYPKPVTEMIPSYDSIAIDYFGTKITYRELNLMIDSVASQLDINKGDV CCCCCCCCHHHHCCCCCHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHCCCCCCCE VIVTMQNIPQFIITEFAVWKKGGIVLPVNPSYTEKELDYIIENSEAKLMIRSCEAINTKK EEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHEEECCCCEEEEEECCCCCCCE IRTITTNPETFHEIPSELKAKWKIIDCEEELDFKSLHREKVDVSPNDLALLVYTSGTTGR EEEEECCCHHHHHCCHHHCCEEEEEECHHHCCHHHHHHHCCCCCCCCEEEEEEECCCCCC PKGVPITHKNIYASSIIYKHWFKFTEKDKVLGIAPFFHITGQIFHITTPLISGSEIVISY CCCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCEEEEEECCCCCCCEEEEEE RFDPTLALRHVEEKKTTVTMAVATAYRAILNEYKGEDLSSMRLWSSGGMPMPRTLEIEWR ECCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEHHH EKIGQWIYMAWGLTETTSPATLWPYPYNGELPVDPETGVVSSGIPVYNTEISIAEDGEVL HHCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCEEECCCCEEECEEEEECCCCEE VRGPQVVSGYWKMEKFRDGWLPTGDIGKIIDGWVYIIDRKKDIINASGFKIMPREVEEVI EECCHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCCCEECHHHHHHHH YMHPAVSEVAVVGLPDQYRGETVAAFIKLKDGYTPNEKVEEEIISLCRKNLAPYKVPKII HCCCCHHHEEEEECCCHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHH RFVNEIPKTPSGKIMRRVFRNERI HHHHHCCCCCCHHHHHHHHHCCCC >Mature Secondary Structure MKYAKGEELEELKYPKPVTEMIPSYDSIAIDYFGTKITYRELNLMIDSVASQLDINKGDV CCCCCCCCHHHHCCCCCHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHCCCCCCCE VIVTMQNIPQFIITEFAVWKKGGIVLPVNPSYTEKELDYIIENSEAKLMIRSCEAINTKK EEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHEEECCCCEEEEEECCCCCCCE IRTITTNPETFHEIPSELKAKWKIIDCEEELDFKSLHREKVDVSPNDLALLVYTSGTTGR EEEEECCCHHHHHCCHHHCCEEEEEECHHHCCHHHHHHHCCCCCCCCEEEEEEECCCCCC PKGVPITHKNIYASSIIYKHWFKFTEKDKVLGIAPFFHITGQIFHITTPLISGSEIVISY CCCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCEEEEEECCCCCCCEEEEEE RFDPTLALRHVEEKKTTVTMAVATAYRAILNEYKGEDLSSMRLWSSGGMPMPRTLEIEWR ECCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEHHH EKIGQWIYMAWGLTETTSPATLWPYPYNGELPVDPETGVVSSGIPVYNTEISIAEDGEVL HHCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCEEECCCCEEECEEEEECCCCEE VRGPQVVSGYWKMEKFRDGWLPTGDIGKIIDGWVYIIDRKKDIINASGFKIMPREVEEVI EECCHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCCCEECHHHHHHHH YMHPAVSEVAVVGLPDQYRGETVAAFIKLKDGYTPNEKVEEEIISLCRKNLAPYKVPKII HCCCCHHHEEEEECCCHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHH RFVNEIPKTPSGKIMRRVFRNERI HHHHHCCCCCCHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9579061; 9384377 [H]