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The map label for this gene is cdc6-1

Identifier: 15920497

GI number: 15920497

Start: 322243

End: 323439

Strand: Reverse

Name: cdc6-1

Synonym: ST0305

Alternate gene names: 15920497

Gene position: 323439-322243 (Counterclockwise)

Preceding gene: 15920498

Following gene: 15920496

Centisome position: 12.0

GC content: 32.58

Gene sequence:

>1197_bases
ATGAGTAAGATTATTGATGAGATATTATCATCCTTAAGTCGTTCTAGAATCTTTAGAAACAGAGAGTTATTATTACCAGA
TTATGTTCCAGAAGAGTTACCTCATAGAGAAGAGCAAATTAAAAGATTAGTTGAAATACTTTCTCCATTAATGCGAGGAG
AAAAACCAAATAATATTTTCATCTATGGTTTAACGGGAACTGGAAAAACTGCTGTAACAAAATTTGTGGTCAAGAAGCTT
CATGAGAAAATATCCAATTCTTTTATTTATGTATATATTAATACTAGGCAAACAGATACCCCATACAGAATTTTGGCTGA
TCTTCTTGAAAATTTAGGTTCAAAGGTCCCTTTTACAGGAATTTCTACTGCAGAATTATATAGGCGATTTATCAAAAAAG
TATTAGAATTAAAGCCAATTTTAGTTATAGTTTTAGATGAGATAGATGCCTTAGTCAAAAAGCATGGTGATGATATTTTA
TATAGATTAACTAGGGCTAATTACGAAATGGGTAAAAGTAAGGTATCTATAATAGGTATAACTAATGATATTAAATTTGT
TGAGTTTCTTGATCCTAGGGTTAAAAGTAGTTTAAGTGAAGAGGAAATAGTATTTCCTCCCTATAATGCTGAAGAATTAG
AGGACATTCTAAAAAGGAGGGCTACTTTAGCATTTTATGATTCCGTCGTTTCTGATGATGTAATTAAATTATGTGCTGCT
ATTGCTGCAAGAGATCATGGAGATGCAAGAAGGGCTTTAGATCTTTTAAGAGTTGCGGGTGAAGTAGCAGAGAGAGATGG
TGCCGAAAAATTAACTATAGAGCATGTAAACAAAGCTAGGGTTGAAATAGAAAGAGATAGAGTATATGAGGTTGTTTCAA
CTCTCCCTTTTCATTCTAAGTTAGTTCTTTTAGCTATTGTGATCGGTGTTAATGAAAAAAGGAGAACCCTTACTACTGGA
GAAGTTTATGACGTATACACTAAGTTAGCTAAGAAGATTGGTGTTGAAAGTGTTACTCAAAGGCGAGTTAGTGATATTAT
TAATGAATTAGATATGTTAGGAATTATTACTGCAAGGGTTGTGAATAGAGGGAGATATGGGAAAACTAAGGAAGTCAACC
TAGCAGTTAATGAGGAAACAGTTATTAAGGCAATTTCTGAAAAAGATAGTAAAATTGCTAGTCTCTGGGATAGATGA

Upstream 100 bases:

>100_bases
GTATTATCTTATAAATCTCCAGTGGAAACAGAGGGGTAATTTACTGGGGGGTAAAATGACTTAGGCTTTTTATGTCATAT
AGTCTCAAAATTAGAGTTTG

Downstream 100 bases:

>100_bases
TGGATACTTTCCTTTAAAATATAAGGGCAGAAACGGCCGTACGGTAATGTTATCAGTAGTTTTTAAGGATTATGATATAA
TTGACATAGATTTTGATTTT

Product: cell division control protein

Products: NA

Alternate protein names: CDC6 homolog 1

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSKIIDEILSSLSRSRIFRNRELLLPDYVPEELPHREEQIKRLVEILSPLMRGEKPNNIFIYGLTGTGKTAVTKFVVKKL
HEKISNSFIYVYINTRQTDTPYRILADLLENLGSKVPFTGISTAELYRRFIKKVLELKPILVIVLDEIDALVKKHGDDIL
YRLTRANYEMGKSKVSIIGITNDIKFVEFLDPRVKSSLSEEEIVFPPYNAEELEDILKRRATLAFYDSVVSDDVIKLCAA
IAARDHGDARRALDLLRVAGEVAERDGAEKLTIEHVNKARVEIERDRVYEVVSTLPFHSKLVLLAIVIGVNEKRRTLTTG
EVYDVYTKLAKKIGVESVTQRRVSDIINELDMLGIITARVVNRGRYGKTKEVNLAVNEETVIKAISEKDSKIASLWDR

Sequences:

>Translated_398_residues
MSKIIDEILSSLSRSRIFRNRELLLPDYVPEELPHREEQIKRLVEILSPLMRGEKPNNIFIYGLTGTGKTAVTKFVVKKL
HEKISNSFIYVYINTRQTDTPYRILADLLENLGSKVPFTGISTAELYRRFIKKVLELKPILVIVLDEIDALVKKHGDDIL
YRLTRANYEMGKSKVSIIGITNDIKFVEFLDPRVKSSLSEEEIVFPPYNAEELEDILKRRATLAFYDSVVSDDVIKLCAA
IAARDHGDARRALDLLRVAGEVAERDGAEKLTIEHVNKARVEIERDRVYEVVSTLPFHSKLVLLAIVIGVNEKRRTLTTG
EVYDVYTKLAKKIGVESVTQRRVSDIINELDMLGIITARVVNRGRYGKTKEVNLAVNEETVIKAISEKDSKIASLWDR
>Mature_397_residues
SKIIDEILSSLSRSRIFRNRELLLPDYVPEELPHREEQIKRLVEILSPLMRGEKPNNIFIYGLTGTGKTAVTKFVVKKLH
EKISNSFIYVYINTRQTDTPYRILADLLENLGSKVPFTGISTAELYRRFIKKVLELKPILVIVLDEIDALVKKHGDDILY
RLTRANYEMGKSKVSIIGITNDIKFVEFLDPRVKSSLSEEEIVFPPYNAEELEDILKRRATLAFYDSVVSDDVIKLCAAI
AARDHGDARRALDLLRVAGEVAERDGAEKLTIEHVNKARVEIERDRVYEVVSTLPFHSKLVLLAIVIGVNEKRRTLTTGE
VYDVYTKLAKKIGVESVTQRRVSDIINELDMLGIITARVVNRGRYGKTKEVNLAVNEETVIKAISEKDSKIASLWDR

Specific function: Might be involved in the initiation of DNA replication

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family

Homologues:

Organism=Homo sapiens, GI4502703, Length=400, Percent_Identity=22.75, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI299890795, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI299890793, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI31795544, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555708, Length=385, Percent_Identity=28.051948051948, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506005, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323575, Length=336, Percent_Identity=26.4880952380952, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355681, Length=415, Percent_Identity=25.3012048192771, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17137456, Length=276, Percent_Identity=26.8115942028986, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDC61_SULTO (Q975X3)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376166.1
- ProteinModelPortal:   Q975X3
- SMR:   Q975X3
- GeneID:   1458210
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0305
- NMPDR:   fig|273063.1.peg.334
- HOGENOM:   HBG553472
- OMA:   ATISFPK
- ProtClustDB:   CLSK802636
- BioCyc:   STOK273063:ST0305-MONOMER
- GO:   GO:0006915
- HAMAP:   MF_01407
- InterPro:   IPR003593
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR002182
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10763:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR02928

Pfam domain/function: PF09079 Cdc6_C; PF00931 NB-ARC

EC number: NA

Molecular weight: Translated: 45310; Mature: 45179

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIDEILSSLSRSRIFRNRELLLPDYVPEELPHREEQIKRLVEILSPLMRGEKPNNIF
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
IYGLTGTGKTAVTKFVVKKLHEKISNSFIYVYINTRQTDTPYRILADLLENLGSKVPFTG
EEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
ISTAELYRRFIKKVLELKPILVIVLDEIDALVKKHGDDILYRLTRANYEMGKSKVSIIGI
CCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEE
TNDIKFVEFLDPRVKSSLSEEEIVFPPYNAEELEDILKRRATLAFYDSVVSDDVIKLCAA
CCCCHHHHHHCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAARDHGDARRALDLLRVAGEVAERDGAEKLTIEHVNKARVEIERDRVYEVVSTLPFHSK
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LVLLAIVIGVNEKRRTLTTGEVYDVYTKLAKKIGVESVTQRRVSDIINELDMLGIITARV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRGRYGKTKEVNLAVNEETVIKAISEKDSKIASLWDR
HHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKIIDEILSSLSRSRIFRNRELLLPDYVPEELPHREEQIKRLVEILSPLMRGEKPNNIF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
IYGLTGTGKTAVTKFVVKKLHEKISNSFIYVYINTRQTDTPYRILADLLENLGSKVPFTG
EEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
ISTAELYRRFIKKVLELKPILVIVLDEIDALVKKHGDDILYRLTRANYEMGKSKVSIIGI
CCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEE
TNDIKFVEFLDPRVKSSLSEEEIVFPPYNAEELEDILKRRATLAFYDSVVSDDVIKLCAA
CCCCHHHHHHCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAARDHGDARRALDLLRVAGEVAERDGAEKLTIEHVNKARVEIERDRVYEVVSTLPFHSK
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LVLLAIVIGVNEKRRTLTTGEVYDVYTKLAKKIGVESVTQRRVSDIINELDMLGIITARV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRGRYGKTKEVNLAVNEETVIKAISEKDSKIASLWDR
HHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479